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Darolutamide in Nonmetastatic, Castration-Resistant Prostate Cancer.

Fizazi K, Shore N, Tammela TL, Ulys A, Vjaters E, Polyakov S, Jievaltas M, Luz M, Alekseev B, Kuss I, Kappeler C, Snapir A, Sarapohja T, Smith MR; ARAMIS Investigators.

N Engl J Med. 2019 Feb 14. doi: 10.1056/NEJMoa1815671. [Epub ahead of print]


When Smoke Does Not Always Mean There Is Fire: Using Isoproterenol for Better Visualization of the Left Atrial Appendage Prior to Transcatheter Closure.

Pandey AC, Smith MR, Olson N, Price MJ, Gibson DN.

JACC Clin Electrophysiol. 2019 Jan;5(1):136-137. doi: 10.1016/j.jacep.2018.09.018. No abstract available.


Homogeneous electrocatalytic oxidation of ammonia to N2 under mild conditions.

Habibzadeh F, Miller SL, Hamann TW, Smith MR 3rd.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2849-2853. doi: 10.1073/pnas.1813368116. Epub 2019 Jan 17.


A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition.

Smith MR, Shock DD, Beard WA, Greenberg MM, Freudenthal BD, Wilson SH.

Nucleic Acids Res. 2019 Jan 16. doi: 10.1093/nar/gkz002. [Epub ahead of print]


Source-Sink Relationships in Crop Plants and Their Influence on Yield Development and Nutritional Quality.

Smith MR, Rao IM, Merchant A.

Front Plant Sci. 2018 Dec 20;9:1889. doi: 10.3389/fpls.2018.01889. eCollection 2018. Review.


Limitations to using phloem sap to assess tree water and nutrient status.

Smith MR, Merchant A.

Tree Physiol. 2018 Dec 14. doi: 10.1093/treephys/tpy132. [Epub ahead of print]


Chemical and isotopic markers detect water deficit and its influence on nutrient allocation in Phaseolus vulgaris.

Smith MR, Fuentes D, Merchant A.

Physiol Plant. 2018 Dec 11. doi: 10.1111/ppl.12899. [Epub ahead of print]


An algorithm for morphological phylogenetic analysis with inapplicable data.

Brazeau MD, Guillerme T, Smith MR.

Syst Biol. 2018 Dec 11. doi: 10.1093/sysbio/syy083. [Epub ahead of print]


Low-dose cadmium disrupts mitochondrial citric acid cycle and lipid metabolism in mouse lung.

Hu X, Chandler JD, Park S, Liu K, Fernandes J, Orr M, Smith MR, Ma C, Kang SM, Uppal K, Jones DP, Go YM.

Free Radic Biol Med. 2019 Feb 1;131:209-217. doi: 10.1016/j.freeradbiomed.2018.12.005. Epub 2018 Dec 6.


Reliability, usefulness and construct validity of the Combined Basketball Skill Test (CBST).

Conte D, Smith MR, Santolamazza F, Favero TG, Tessitore A, Coutts A.

J Sports Sci. 2018 Nov 30:1-7. doi: 10.1080/02640414.2018.1551046. [Epub ahead of print]


Critical period plasticity-related transcriptional aberrations in schizophrenia and bipolar disorder.

Smith MR, Readhead B, Dudley JT, Morishita H.

Schizophr Res. 2018 Nov 12. pii: S0920-9964(18)30623-6. doi: 10.1016/j.schres.2018.10.021. [Epub ahead of print]


Evaluation of Dynamic Time Warp Barycenter Averaging (DBA) for its Potential in Generating a Consensus Nanopore Signal for Genetic and Epigenetic Sequences.

Chan RSL, Gordon P, Smith MR.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:2821-2824. doi: 10.1109/EMBC.2018.8512873.


Integrative bioinformatics identifies postnatal lead (Pb) exposure disrupts developmental cortical plasticity.

Smith MR, Yevoo P, Sadahiro M, Austin C, Amarasiriwardena C, Awawda M, Arora M, Dudley JT, Morishita H.

Sci Rep. 2018 Nov 6;8(1):16388. doi: 10.1038/s41598-018-34592-4.


Mental Fatigue in Football: Is it Time to Shift the Goalposts? An Evaluation of the Current Methodology.

Thompson CJ, Fransen J, Skorski S, Smith MR, Meyer T, Barrett S, Coutts AJ.

Sports Med. 2019 Feb;49(2):177-183. doi: 10.1007/s40279-018-1016-z.


Hyoliths with pedicles illuminate the origin of the brachiopod body plan.

Sun H, Smith MR, Zeng H, Zhao F, Li G, Zhu M.

Proc Biol Sci. 2018 Sep 26;285(1887). pii: 20181780. doi: 10.1098/rspb.2018.1780.


Pharmacological risk factors associated with hospital readmission rates in a psychiatric cohort identified using prescriptome data mining.

Shameer K, Perez-Rodriguez MM, Bachar R, Li L, Johnson A, Johnson KW, Glicksberg BS, Smith MR, Readhead B, Scarpa J, Jebakaran J, Kovatch P, Lim S, Goodman W, Reich DL, Kasarskis A, Tatonetti NP, Dudley JT.

BMC Med Inform Decis Mak. 2018 Sep 14;18(Suppl 3):79. doi: 10.1186/s12911-018-0653-3.


Predicting nutrient content of ray-finned fishes using phylogenetic information.

Vaitla B, Collar D, Smith MR, Myers SS, Rice BL, Golden CD.

Nat Commun. 2018 Sep 25;9(1):3742. doi: 10.1038/s41467-018-06199-w.


Effect of apalutamide on health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: an analysis of the SPARTAN randomised, placebo-controlled, phase 3 trial.

Saad F, Cella D, Basch E, Hadaschik BA, Mainwaring PN, Oudard S, Graff JN, McQuarrie K, Li S, Hudgens S, Lawson J, Lopez-Gitlitz A, Yu MK, Smith MR, Small EJ.

Lancet Oncol. 2018 Oct;19(10):1404-1416. doi: 10.1016/S1470-2045(18)30456-X. Epub 2018 Sep 10.


Clinical Development of Darolutamide: A Novel Androgen Receptor Antagonist for the Treatment of Prostate Cancer.

Fizazi K, Smith MR, Tombal B.

Clin Genitourin Cancer. 2018 Oct;16(5):332-340. doi: 10.1016/j.clgc.2018.07.017. Epub 2018 Jul 24. Review.


Achieving High Ortho Selectivity in Aniline C-H Borylations by Modifying Boron Substituents.

Smith MR 3rd, Bisht R, Haldar C, Pandey G, Dannatt JE, Ghaffari B, Maleczka RE Jr, Chattopadhyay B.

ACS Catal. 2018 Jul 6;8(7):6216-6223. doi: 10.1021/acscatal.8b00641. Epub 2018 May 9.


The relationship between deficit in digit span and genotype in nonsense mutation Duchenne muscular dystrophy.

Thangarajh M, Elfring GL, Trifillis P, McIntosh J, Peltz SW; Ataluren Phase 2b Study Group.

Neurology. 2018 Sep 25;91(13):e1215-e1219. doi: 10.1212/WNL.0000000000006245. Epub 2018 Aug 22.


Assessment of the Stability of von Willebrand Profile Clotting Factors and Platelet Dense Granule Testing Following Air Transport.

Mai DB, Smith MR, Gunning WT 3rd.

Clin Appl Thromb Hemost. 2018 Nov;24(8):1261-1266. doi: 10.1177/1076029618794298. Epub 2018 Aug 16.


Impact of Historical Changes in Coarse Cereals Consumption in India on Micronutrient Intake and Anemia Prevalence.

DeFries R, Chhatre A, Davis KF, Dutta A, Fanzo J, Ghosh-Jerath S, Myers S, Rao ND, Smith MR.

Food Nutr Bull. 2018 Sep;39(3):377-392. doi: 10.1177/0379572118783492. Epub 2018 Aug 1.


Lenalidomide consolidation benefits patients with CLL receiving chemoimmunotherapy: results for CALGB 10404 (Alliance).

Byrd JC, Ruppert AS, Heerema NA, Halvorson AE, Hoke E, Smith MR, Godwin JE, Couban S, Fehniger TA, Thirman MJ, Tallman MS, Appelbaum FR, Stone RM, Robinson S, Chang JE, Mandrekar SJ, Larson RA.

Blood Adv. 2018 Jul 24;2(14):1705-1718. doi: 10.1182/bloodadvances.2017015396.


Possible Drug-nutraceutical Interaction leading to Unexpected Sequelae after Inguinal Hernia Repair.

Smith MR, Faingold C, Mellinger JD.

Am J Case Rep. 2018 Jul 17;19:836-838. doi: 10.12659/AJCR.908117.


Apalutamide and Metastasis-free Survival in Prostate Cancer.

Smith MR, Yu MK, Small EJ.

N Engl J Med. 2018 Jun 28;378(26):2542. doi: 10.1056/NEJMc1806189. No abstract available.


Progress in Nonmetastatic Prostate Cancer.

Smith MR.

N Engl J Med. 2018 Jun 28;378(26):2531-2532. doi: 10.1056/NEJMe1805733. No abstract available.


Early Generated B-1-Derived B Cells Have the Capacity To Progress To Become Mantle Cell Lymphoma-like Neoplasia in Aged Mice.

Hayakawa K, Formica AM, Nakao Y, Ichikawa D, Shinton SA, Brill-Dashoff J, Smith MR, Morse HC 3rd, Hardy RR.

J Immunol. 2018 Jul 15;201(2):804-813. doi: 10.4049/jimmunol.1800400. Epub 2018 Jun 13.


Reply to C. Ren et al.

Heller G, McCormack R, Kheoh T, Molina A, Smith MR, Dreicer R, Saad F, de Wit R, Aftab DT, Hirmand M, Limon-Carrera A, Fizazi K, Fleisher M, de Bono JS, Scher HI.

J Clin Oncol. 2018 Aug 1;36(22):2354-2356. doi: 10.1200/JCO.2018.78.2672. Epub 2018 Jun 12. No abstract available.


Nonmammalian Models of Huntington's Disease.

Chongtham A, Barbaro B, Filip T, Syed A, Huang W, Smith MR, Marsh JL.

Methods Mol Biol. 2018;1780:75-96. doi: 10.1007/978-1-4939-7825-0_5.


Optimal use of novel agents in chronic lymphocytic leukemia.

Smith MR, Weiss RF.

Leuk Res. 2018 May 7;70:37-40. doi: 10.1016/j.leukres.2018.05.001. [Epub ahead of print]


Protein-Scaffold Directed Nanoscale Assembly of T Cell Ligands: Artificial Antigen Presentation with Defined Valency, Density, and Ratio.

Smith MR, Tolbert SV, Wen F.

ACS Synth Biol. 2018 Jun 15;7(6):1629-1639. doi: 10.1021/acssynbio.8b00119. Epub 2018 May 21.


Integrative metabolomics and transcriptomics signatures of clinical tolerance to Plasmodium vivax reveal activation of innate cell immunity and T cell signaling.

Gardinassi LG, Arévalo-Herrera M, Herrera S, Cordy RJ, Tran V, Smith MR, Johnson MS, Chacko B, Liu KH, Darley-Usmar VM, Go YM; MaHPIC Consortium, Jones DP, Galinski MR, Li S.

Redox Biol. 2018 Jul;17:158-170. doi: 10.1016/j.redox.2018.04.011. Epub 2018 Apr 11.


Mental Fatigue and Soccer: Current Knowledge and Future Directions.

Smith MR, Thompson C, Marcora SM, Skorski S, Meyer T, Coutts AJ.

Sports Med. 2018 Jul;48(7):1525-1532. doi: 10.1007/s40279-018-0908-2. Review.


Co-expression of MYC and BCL2 predicts poorer outcomes for relapsed/refractory diffuse large B-cell lymphoma with R-ICE and intent to transplant.

Allen J, Ruano Mendez AL, Rybicki L, Sawalha Y, Jagadeesh D, Dean R, Pohlman B, Smith MR, Hsi ED, Hill BT.

Ther Adv Hematol. 2018 Apr;9(4):81-87. doi: 10.1177/2040620718759249. Epub 2018 Mar 29.


In cell mutational interference mapping experiment (in cell MIME) identifies the 5' polyadenylation signal as a dual regulator of HIV-1 genomic RNA production and packaging.

Smyth RP, Smith MR, Jousset AC, Despons L, Laumond G, Decoville T, Cattenoz P, Moog C, Jossinet F, Mougel M, Paillart JC, von Kleist M, Marquet R.

Nucleic Acids Res. 2018 May 18;46(9):e57. doi: 10.1093/nar/gky152.


Shaping a valued learning journey: Student satisfaction with learning in undergraduate nursing programs, a grounded theory study.

Smith MR, Grealish L, Henderson S.

Nurse Educ Today. 2018 May;64:175-179. doi: 10.1016/j.nedt.2018.02.020. Epub 2018 Feb 22.


Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer.

Smith MR, Saad F, Chowdhury S, Oudard S, Hadaschik BA, Graff JN, Olmos D, Mainwaring PN, Lee JY, Uemura H, Lopez-Gitlitz A, Trudel GC, Espina BM, Shu Y, Park YC, Rackoff WR, Yu MK, Small EJ; SPARTAN Investigators.

N Engl J Med. 2018 Apr 12;378(15):1408-1418. doi: 10.1056/NEJMoa1715546. Epub 2018 Feb 8.


An RNA-Based Digital Circulating Tumor Cell Signature Is Predictive of Drug Response and Early Dissemination in Prostate Cancer.

Miyamoto DT, Lee RJ, Kalinich M, LiCausi JA, Zheng Y, Chen T, Milner JD, Emmons E, Ho U, Broderick K, Silva E, Javaid S, Kwan TT, Hong X, Dahl DM, McGovern FJ, Efstathiou JA, Smith MR, Sequist LV, Kapur R, Wu CL, Stott SL, Ting DT, Giobbie-Hurder A, Toner M, Maheswaran S, Haber DA.

Cancer Discov. 2018 Mar;8(3):288-303. doi: 10.1158/2159-8290.CD-16-1406. Epub 2018 Jan 4.


Mental Fatigue Impairs Physical Performance in Young Swimmers.

Penna EM, Filho E, Wanner SP, Campos BT, Quinan GR, Mendes TT, Smith MR, Prado LS.

Pediatr Exerc Sci. 2018 May 1;30(2):208-215. doi: 10.1123/pes.2017-0128. Epub 2017 Dec 23.


Circulating Tumor Cell Number as a Response Measure of Prolonged Survival for Metastatic Castration-Resistant Prostate Cancer: A Comparison With Prostate-Specific Antigen Across Five Randomized Phase III Clinical Trials.

Heller G, McCormack R, Kheoh T, Molina A, Smith MR, Dreicer R, Saad F, de Wit R, Aftab DT, Hirmand M, Limon A, Fizazi K, Fleisher M, de Bono JS, Scher HI.

J Clin Oncol. 2018 Feb 20;36(6):572-580. doi: 10.1200/JCO.2017.75.2998. Epub 2017 Dec 22.


Frequency distribution of osteochondral fragmentation of the dorsoproximal articular surface of the proximal phalanx in racing Thoroughbreds in the UK.

Walsh R, Smith MRW, Wright IM.

Equine Vet J. 2018 Sep;50(5):624-628. doi: 10.1111/evj.12795. Epub 2018 Jan 25.


Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.

Neelapu SS, Locke FL, Bartlett NL, Lekakis LJ, Miklos DB, Jacobson CA, Braunschweig I, Oluwole OO, Siddiqi T, Lin Y, Timmerman JM, Stiff PJ, Friedberg JW, Flinn IW, Goy A, Hill BT, Smith MR, Deol A, Farooq U, McSweeney P, Munoz J, Avivi I, Castro JE, Westin JR, Chavez JC, Ghobadi A, Komanduri KV, Levy R, Jacobsen ED, Witzig TE, Reagan P, Bot A, Rossi J, Navale L, Jiang Y, Aycock J, Elias M, Chang D, Wiezorek J, Go WY.

N Engl J Med. 2017 Dec 28;377(26):2531-2544. doi: 10.1056/NEJMoa1707447. Epub 2017 Dec 10.


Loss-of-function of neuroplasticity-related genes confers risk for human neurodevelopmental disorders.

Smith MR, Glicksberg BS, Li L, Chen R, Morishita H, Dudley JT.

Pac Symp Biocomput. 2018;23:68-79.


Efficacy of Standard Dose R-CHOP Alternating With R-HDAC Followed by Autologous Hematopoietic Cell Transplantation as Initial Therapy of Mantle Cell Lymphoma, a Single-Institution Experience.

Sawalha Y, Hill BT, Rybicki LA, Sun D, Dean RM, Jagadeesh D, Hamilton BK, Gerds AT, Sobecks RM, Andresen S, Liu HK, Majhail NS, Pohlman B, Kalaycio ME, Bolwell BJ, Smith MR.

Clin Lymphoma Myeloma Leuk. 2018 Jan;18(1):e95-e102. doi: 10.1016/j.clml.2017.11.002. Epub 2017 Dec 6.


Radium-223 Safety, Efficacy, and Concurrent Use with Abiraterone or Enzalutamide: First U.S. Experience from an Expanded Access Program.

Sartor O, Vogelzang NJ, Sweeney C, Fernandez DC, Almeida F, Iagaru A, Brown A Jr, Smith MR, Agrawal M, Dicker AP, Garcia JA, Lutzky J, Wong YN, Petrenciuc O, Gratt J, Shore ND, Morris MJ; U.S. Expanded Access Program Investigators.

Oncologist. 2018 Feb;23(2):193-202. doi: 10.1634/theoncologist.2017-0413. Epub 2017 Nov 28.


Orthrozanclus elongata n. sp. and the significance of sclerite-covered taxa for early trochozoan evolution.

Zhao F, Smith MR, Yin Z, Zeng H, Li G, Zhu M.

Sci Rep. 2017 Nov 24;7(1):16232. doi: 10.1038/s41598-017-16304-6.


Molecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors.

Meixenberger K, Yousef KP, Smith MR, Somogyi S, Fiedler S, Bartmeyer B, Hamouda O, Bannert N, von Kleist M, Kücherer C.

Virol J. 2017 Nov 14;14(1):223. doi: 10.1186/s12985-017-0887-1.


Experiences of women discharged less than 24 hours post vaginal birth: a systematic review protocol.

Cusack L, Smith MR.

JBI Database System Rev Implement Rep. 2017 Nov;15(11):2599-2603. doi: 10.11124/JBISRIR-2017-003411.


Naming disease states for clinical utility in prostate cancer: a rose by any other name might not smell as sweet.

Armstrong AJ, Antonarakis ES, Taplin ME, Kelly WK, Beltran H, Fizazi K, Dahut WL, Shore N, Slovin S, George D, Carducci MA, Corn P, Danila D, Dreicer R, Heath E, Rathkopf D, Liu G, Nanus D, Stein M, Smith MR, Sternberg C, Wilding G, Nelson PS, Halabi S, Kantoff P, Clarke NW, Evans CP, Heidenreich A, Mottet N, Gleave M, Morris MJ, Scher HI.

Ann Oncol. 2018 Jan 1;29(1):23-25. doi: 10.1093/annonc/mdx648. No abstract available.

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