Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 498

1.

Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators.

Pinkerton AB, Peddibhotla S, Yamamoto F, Slosky LM, Bai Y, Maloney P, Hershberger P, Hedrick MP, Falter B, Ardecky RJ, Smith LH, Chung TDY, Jackson MR, Caron MG, Barak LS.

J Med Chem. 2019 Sep 12;62(17):8357-8363. doi: 10.1021/acs.jmedchem.9b00340. Epub 2019 Aug 20.

PMID:
31390201
2.

The future of pediatric nursing science.

Harrison TM, Steward D, Tucker S, Fortney CA, Militello LK, Smith LH, Thrane S, Tubbs-Cooley HL, Pickler RH.

Nurs Outlook. 2019 Jun 27. pii: S0029-6554(18)30748-6. doi: 10.1016/j.outlook.2019.06.020. [Epub ahead of print]

PMID:
31375348
3.

Mediational E-values: Approximate Sensitivity Analysis for Unmeasured Mediator-Outcome Confounding.

Smith LH, VanderWeele TJ.

Epidemiology. 2019 Nov;30(6):835-837. doi: 10.1097/EDE.0000000000001064.

PMID:
31348008
4.

"Bringing Tap Back": Expanding the "Sodabriety" Teen Advisory Council Approach in Tennessee High Schools.

Smith LH, Sexton C, Pettigrew K, Eastburn S.

J Sch Nurs. 2019 May 20:1059840519850881. doi: 10.1177/1059840519850881. [Epub ahead of print]

PMID:
31109240
5.

Bounding Bias Due to Selection.

Smith LH, VanderWeele TJ.

Epidemiology. 2019 Jul;30(4):509-516. doi: 10.1097/EDE.0000000000001032.

6.

Sugar-sweetened beverage behaviors of Tennessee school children: How do parent- and child-report compare on school days and nonschool days?

Smith LH, Baumker E.

J Spec Pediatr Nurs. 2019 Jan;24(1):e12231. doi: 10.1111/jspn.12231. Epub 2019 Jan 19.

PMID:
30659751
7.

Rates of Obesity and Obesogenic Behaviors of Rural Appalachian Adolescents: How Do They Compare to Other Adolescents or Recommendations?

Smith LH, Laurent D, Baumker E, Petosa RL.

J Phys Act Health. 2018 Nov 1;15(11):874-881. doi: 10.1123/jpah.2017-0602. Epub 2018 Oct 13.

8.

A Pharmacochaperone-Based High-Throughput Screening Assay for the Discovery of Chemical Probes of Orphan Receptors.

Morfa CJ, Bassoni D, Szabo A, McAnally D, Sharir H, Hood BL, Vasile S, Wehrman T, Lamerdin J, Smith LH.

Assay Drug Dev Technol. 2018 Oct;16(7):384-396. doi: 10.1089/adt.2018.868. Epub 2018 Sep 22.

9.

Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization.

McAnally D, Siddiquee K, Gomaa A, Szabo A, Vasile S, Maloney PR, Divlianska DB, Peddibhotla S, Morfa CJ, Hershberger P, Falter R, Williamson R, Terry DB, Farjo R, Pinkerton AB, Qi X, Quigley J, Boulton ME, Grant MB, Smith LH.

PLoS One. 2018 Sep 12;13(9):e0202436. doi: 10.1371/journal.pone.0202436. eCollection 2018.

11.

Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan.

Rai R, Ghosh AK, Eren M, Mackie AR, Levine DC, Kim SY, Cedernaes J, Ramirez V, Procissi D, Smith LH, Woodruff TK, Bass J, Vaughan DE.

Cell Rep. 2017 Nov 7;21(6):1471-1480. doi: 10.1016/j.celrep.2017.10.057.

12.

Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress.

Kirby RJ, Divlianska DB, Whig K, Bryan N, Morfa CJ, Koo A, Nguyen KH, Maloney P, Peddibhotla S, Sessions EH, Hershberger PM, Smith LH, Malany S.

J Pharmacol Exp Ther. 2018 Jan;364(1):87-96. doi: 10.1124/jpet.117.243717. Epub 2017 Nov 3. Erratum in: J Pharmacol Exp Ther. 2018 Feb;364(2):179.

PMID:
29101218
13.

Maternal Prepregnancy Weight and Children's Behavioral and Emotional Outcomes.

Deardorff J, Smith LH, Petito L, Kim H, Abrams BF.

Am J Prev Med. 2017 Oct;53(4):432-440. doi: 10.1016/j.amepre.2017.05.013. Epub 2017 Jul 13.

14.

The Use of Endometrial Cancer Patient-Derived Organoid Culture for Drug Sensitivity Testing Is Feasible.

Girda E, Huang EC, Leiserowitz GS, Smith LH.

Int J Gynecol Cancer. 2017 Oct;27(8):1701-1707. doi: 10.1097/IGC.0000000000001061.

15.

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

Li J, Yakushi T, Parlati F, Mackinnon AL, Perez C, Ma Y, Carter KP, Colayco S, Magnuson G, Brown B, Nguyen K, Vasile S, Suyama E, Smith LH, Sergienko E, Pinkerton AB, Chung TDY, Palmer AE, Pass I, Hess S, Cohen SM, Deshaies RJ.

Nat Chem Biol. 2017 May;13(5):486-493. doi: 10.1038/nchembio.2326. Epub 2017 Feb 28.

16.

Assessment of drug-induced arrhythmic risk using limit cycle and autocorrelation analysis of human iPSC-cardiomyocyte contractility.

Kirby RJ, Qi F, Phatak S, Smith LH, Malany S.

Toxicol Appl Pharmacol. 2016 Aug 15;305:250-258. doi: 10.1016/j.taap.2016.06.025. Epub 2016 Jun 23.

PMID:
27343406
17.

Effective Practices to Improve Recruitment, Retention, and Partnerships in School-Based Studies.

Smith LH, Petosa RL.

J Pediatr Health Care. 2016 Sep-Oct;30(5):495-8. doi: 10.1016/j.pedhc.2016.05.004. Epub 2016 Jun 16. No abstract available.

18.

A Structured Peer-Mentoring Method for Physical Activity Behavior Change Among Adolescents.

Smith LH, Petosa RL.

J Sch Nurs. 2016 Oct;32(5):315-23. doi: 10.1177/1059840516644955. Epub 2016 May 4. Review.

19.

Nonlinear mappings between discrete and simultaneous motions to decrease training burden of simultaneous pattern recognition myoelectric control.

Ingraham KA, Smith LH, Simon AM, Hargrove LJ.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:1675-8. doi: 10.1109/EMBC.2015.7318698.

PMID:
26736598
20.

Real-time simultaneous myoelectric control by transradial amputees using linear and probability-weighted regression.

Smith LH, Kuiken TA, Hargrove LJ.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:1119-23. doi: 10.1109/EMBC.2015.7318562.

PMID:
26736462
21.

Use of probabilistic weights to enhance linear regression myoelectric control.

Smith LH, Kuiken TA, Hargrove LJ.

J Neural Eng. 2015 Dec;12(6):066030. doi: 10.1088/1741-2560/12/6/066030. Epub 2015 Nov 23.

22.

In Vitro and In Vivo Assessment of ADME and PK Properties During Lead Selection and Lead Optimization – Guidelines, Benchmarks and Rules of Thumb.

Chung TDY, Terry DB, Smith LH.

In: Sittampalam GS, Grossman A, Brimacombe K, Arkin M, Auld D, Austin CP, Baell J, Bejcek B, Caaveiro JMM, Chung TDY, Coussens NP, Dahlin JL, Devanaryan V, Foley TL, Glicksman M, Hall MD, Haas JV, Hoare SRJ, Inglese J, Iversen PW, Kahl SD, Kales SC, Kirshner S, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Saradjian P, Trask OJ Jr., Weidner JR, Wildey MJ, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.
2015 Sep 9.

23.

Exploring Environment-Intervention Fit: A Study of a Work Environment Intervention Program for the Care Sector.

Smith LH, Aust B, Flyvholm MA.

ScientificWorldJournal. 2015;2015:272347. doi: 10.1155/2015/272347. Epub 2015 Aug 25.

24.

Evaluation of Linear Regression Simultaneous Myoelectric Control Using Intramuscular EMG.

Smith LH, Kuiken TA, Hargrove LJ.

IEEE Trans Biomed Eng. 2016 Apr;63(4):737-46. doi: 10.1109/TBME.2015.2469741. Epub 2015 Aug 20.

25.

Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes.

Peddibhotla S, Fontaine P, Leung CK, Maloney P, Hershberger PM, Wang Y, Bousquet MS, Luesch H, Mangravita-Novo A, Pinkerton AB, Smith LH, Malany S, Choe K.

ACS Chem Biol. 2015 Aug 21;10(8):1871-9. doi: 10.1021/acschembio.5b00304. Epub 2015 May 22.

PMID:
25946346
26.

Small Molecules Targeting the Mitochondrial Permeability Transition.

Sileikyte J, Roy S, Porubsky P, Neuenswander B, Wang J, Hedrick M, Pinkerton AB, Salaniwal S, Kung P, Mangravita-Novo A, Smith LH, Bourdette DN, Jackson MR, Aubé J, Chung TDY, Schoenen FJ, Forte MA, Bernardi P.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2014 Apr 15 [updated 2015 Jan 16].

27.

Functional Antagonists of EBI-2.

Ardecky R, Sergienko E, Zou J, Ganji S, Brown B, Sun Q, Ma CT, Hood B, Nguyen K, Vasile S, Suyama E, Mangravita-Novo A, Salaniwal S, Kung P, Smith LH, Chung TDY, Jackson MR, Pinkerton AB, Rickert R.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2014 Apr 15 [updated 2015 Jan 16].

28.

Allosteric Small Molecule Inhibitors of LMPTP.

Ardecky RJ, Hedrick MP, Stanford SM, Bliss MR, Zou J, Gosalia P, Yamamoto F, Milewski M, Barron N, Sun Q, Ganji S, Mehta A, Sugarman E, Nguyen K, Vasile S, Suyama E, Mangravita-Novo A, Salaniwal S, Kung P, Smith LH, Sergienko E, Chung TDY, Pinkerton AB, Bottini N.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2014 Apr 15 [updated 2015 Jan 16].

29.

Inhibitors of Myocyte Triacylglyceride Accumulation.

Hershberger PM, Sugarman E, Maloney P, Peddibhotla S, Koo A, Suyama E, Ruidiaz ME, Heynen-Genel S, Nguyen KH, Vasile S, Mangravita-Novo A, Smith LH, Soundarapandian MM, Salaniwal S, Kung P, Vega RB, Chung TDY, Pinkerton AB, Malany S, Kelly DP.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Dec 15 [updated 2015 Feb 11].

30.

Targeting α-synuclein oligomers by protein-fragment complementation for drug discovery in synucleinopathies.

Moussaud S, Malany S, Mehta A, Vasile S, Smith LH, McLean PJ.

Expert Opin Ther Targets. 2015 May;19(5):589-603. doi: 10.1517/14728222.2015.1009448. Epub 2015 Mar 18.

31.

Myoelectric Control System and Task-Specific Characteristics Affect Voluntary Use of Simultaneous Control.

Smith LH, Kuiken TA, Hargrove LJ.

IEEE Trans Neural Syst Rehabil Eng. 2016 Jan;24(1):109-16. doi: 10.1109/TNSRE.2015.2410755. Epub 2015 Mar 6.

32.

Targeted muscle reinnervation and advanced prosthetic arms.

Cheesborough JE, Smith LH, Kuiken TA, Dumanian GA.

Semin Plast Surg. 2015 Feb;29(1):62-72. doi: 10.1055/s-0035-1544166.

33.

Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response.

Flaherty DP, Miller JR, Garshott DM, Hedrick M, Gosalia P, Li Y, Milewski M, Sugarman E, Vasile S, Salaniwal S, Su Y, Smith LH, Chung TD, Pinkerton AB, Aubé J, Callaghan MU, Golden JE, Fribley AM, Kaufman RJ.

ACS Med Chem Lett. 2014 Oct 29;5(12):1278-1283. eCollection 2014 Dec 11.

34.

Real-time simultaneous and proportional myoelectric control using intramuscular EMG.

Smith LH, Kuiken TA, Hargrove LJ.

J Neural Eng. 2014 Dec;11(6):066013. doi: 10.1088/1741-2560/11/6/066013. Epub 2014 Nov 14.

35.

A high throughput screen for inhibitors of nematode detoxification genes.

Peddibhotla S, Leung CK, Maloney P, Hershberger PM, Nguyen K, Vasile S, Suyama E, Kane A, Bousquet MS, Leusch H, Stonich D, Mangravita-Novo A, Salaniwal S, Kung P, Diwan J, Smith LH, Chung TDY, Pinkerton AB, Malany S, Choe K.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Apr 11 [updated 2014 Jan 13].

36.

Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus.

Schroeder CE, Yao T, Sotsky J, Smith RA, Roy S, Chu YK, Guo H, Tower NA, Noah JW, McKellip S, Sosa M, Rasmussen L, Smith LH, White EL, Aubé J, Jonsson CB, Chung D, Golden JE.

J Med Chem. 2014 Oct 23;57(20):8608-21. doi: 10.1021/jm501203v. Epub 2014 Oct 7.

37.

Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma.

Brun SN, Markant SL, Esparza LA, Garcia G, Terry D, Huang JM, Pavlyukov MS, Li XN, Grant GA, Crawford JR, Levy ML, Conway EM, Smith LH, Nakano I, Berezov A, Greene MI, Wang Q, Wechsler-Reya RJ.

Oncogene. 2015 Jul;34(29):3770-9. doi: 10.1038/onc.2014.304. Epub 2014 Sep 22.

38.

Exendin-4 improves cardiac function in mice overexpressing monocyte chemoattractant protein-1 in cardiomyocytes.

Younce CW, Niu J, Ayala J, Burmeister MA, Smith LH, Kolattukudy P, Ayala JE.

J Mol Cell Cardiol. 2014 Nov;76:172-6. doi: 10.1016/j.yjmcc.2014.08.022. Epub 2014 Sep 6.

39.

Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.

Bravo Y, Teriete P, Dhanya RP, Dahl R, Lee PS, Kiffer-Moreira T, Ganji SR, Sergienko E, Smith LH, Farquharson C, Millán JL, Cosford ND.

Bioorg Med Chem Lett. 2014 Sep 1;24(17):4308-11. doi: 10.1016/j.bmcl.2014.07.013. Epub 2014 Jul 15.

40.

Clinical pharmacogenetics implementation consortium guidelines for CYP2C9 and HLA-B genotypes and phenytoin dosing.

Caudle KE, Rettie AE, Whirl-Carrillo M, Smith LH, Mintzer S, Lee MT, Klein TE, Callaghan JT; Clinical Pharmacogenetics Implementation Consortium.

Clin Pharmacol Ther. 2014 Nov;96(5):542-8. doi: 10.1038/clpt.2014.159. Epub 2014 Aug 6.

41.

Small-molecule antagonists of Gli function.

Ardecky R, Magnuson GK, Zou J, Ganji SR, Brown B, Ngo T, Lee J, Zeng FY, Sun Q, Stonich D, Salaniwal S, Sakata T, Rack PG, Casabar JKT, Mangravita-Novo A, Smith LH, Sergienko E, Chung TDY, Pinkerton AB, Pass I, Chen JK.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Dec 17 [updated 2014 May 13].

42.

Probing the CXCR6/CXCL16 Axis: Targeting Prevention of Prostate Cancer Metastasis.

Hershberger PM, Peddibhotla S, Sugarman E, Maloney P, Key D, Suyama E, Nguyen K, Vasile S, Kraft M, Stonich D, Mangravita-Novo A, Vicchiarelli M, Gosalia P, Milewski M, Li L, Hedrick M, Sun Q, Sergienko E, Cheltsov A, Salanawil S, Diwan J, Smith LH, Taichman RS, Chung TDY, Pinkerton AB, Malany S, Roth GP.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Dec 15 [updated 2014 May 13].

43.

Selective UBC 13 Inhibitors.

Ardecky R, Madiraj C, Matsuzawa S, Zou J, Ganji S, Pass I, Ngo TA, Pinkerton AB, Sergienko E, Su Y, Stonich D, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Diwan J, Chung TDY, Matsuzawa Y, Wimer C, Diaz PW, Reed JC.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Apr 16 [updated 2014 May 13].

44.

Potent inhibitors of lipid droplet formation.

Zou J, Ganji S, Pass I, Ardecky R, Peddibhotla M, Loribelle M, Heynen-Genel S, Sauer M, Pass I, Vasile S, Suyama E, Malany S, Mangravita-Novo A, Vicchiarelli M, McAnally D, Cheltsov A, Derek S, Shi S, Su Y, Zeng FY, Pinkerton AB, Smith LH, Kim S, Ngyuen H, Zeng FY, Diwan J, Heisel AJ, Coleman R, McDonough PM, Chung TDY.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Oct 31 [updated 2014 May 13].

45.

Real-time and offline performance of pattern recognition myoelectric control using a generic electrode grid with targeted muscle reinnervation patients.

Tkach DC, Young AJ, Smith LH, Rouse EJ, Hargrove LJ.

IEEE Trans Neural Syst Rehabil Eng. 2014 Jul;22(4):727-34. doi: 10.1109/TNSRE.2014.2302799. Epub 2014 Feb 11.

PMID:
24760931
46.

Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence.

Dhanya RP, Sheffler DJ, Dahl R, Davis M, Lee PS, Yang L, Nickols HH, Cho HP, Smith LH, D'Souza MS, Conn PJ, Der-Avakian A, Markou A, Cosford ND.

J Med Chem. 2014 May 22;57(10):4154-72. doi: 10.1021/jm5000563. Epub 2014 May 9.

47.

Selective inhibitors of FAS-TE.

Ardecky R, Hedrick MP, Gosalia P, Yamamoto F, Milewski M, Barron N, Sun Q, Zhou J, Ganji S, Mehta A, Sugarman E, Nguyen K, Vasile S, Suyama E, Teriete P, Sheffler D, Lee PS, Mattmann M, De Ingeniis J, Stonich D, Mangravita-Novo A, Salaniwal S, Kung P, Diwan J, Smith LH, Sergienko E, Chung TDY, Pinkerton AB, Cosford NDP, Smith JW.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Apr 12 [updated 2014 Jan 13].

48.

Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor.

Peddibhotla S, Hedrick MP, Hershberger P, Maloney PR, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, Salaniwal S, Stonich D, Su Y, Mangravita-Novo A, Vicchiarelli M, Roth GP, Smith LH, Chung TD, Hanson GR, Thomas JB, Caron MG, Barak LS, Pinkerton AB.

ACS Med Chem Lett. 2013 Jul 20;4(9):846-851.

49.

Small Molecule Agonists for the Neurotensin 1 Receptor (NTR1 Agonists).

Hershberger P, Hedrick M, Peddibhotla S, Maloney P, Li Y, Milewski M, Gosalia P, Gray W, Mehta A, Sugarman E, Hood B, Suyama E, Nguyen K, Heynen-Genel S, Vasile S, Salaniwal S, Stonich D, Su Y, Mangravita-Novo A, Vicchiarelli M, Smith LH, Roth G, Diwan J, Chung TDY, Caron MG, Thomas JB, Pinkerton AB, Barak LR.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Apr 8 [updated 2013 Mar 7].

50.

A 2nd Selective Inhibitor of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase (PfG6PDH) - Probe 2.

Maloney P, Hedrick M, Peddibhotla S, Hershberger P, Milewski M, Gosalia P, Li L, Preuss J, Sugarman E, Hood B, Suyama E, Nguyen K, Vasile S, Sergienko E, Salanawil S, Stonich D, Su Y, Dahl R, Mangravita-Novo A, Vicchiarelli M, McAnally D, Smith LH, Roth G, Diwan J, Chung TDY, Pinkerton AB, Bode L, Becker K.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Mar 28 [updated 2013 Mar 14].

Supplemental Content

Loading ...
Support Center