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Leucocytosis is associated with retinopathy of prematurity in extremely preterm infants.

Lundgren P, Klevebro S, Brodin P, Smith LEH, Hallberg B, Hellström A.

Acta Paediatr. 2019 Jul;108(7):1357-1358. doi: 10.1111/apa.14798. Epub 2019 Apr 12. No abstract available.


Tailored vs Static Oxygen Saturation Targets to Prevent Retinopathy of Prematurity.

Hellström A, Hård AL, Smith LEH.

JAMA Ophthalmol. 2019 Feb 14. doi: 10.1001/jamaophthalmol.2018.6940. [Epub ahead of print] No abstract available.


Knowledge, attitudes and practices with regard to schistosomiasis prevention and control: Two cross-sectional household surveys before and after a Community Dialogue intervention in Nampula province, Mozambique.

Rassi C, Martin S, Graham K, de Cola MA, Christiansen-Jucht C, Smith LE, Jive E, Phillips AE, Newell JN, Massangaie M.

PLoS Negl Trop Dis. 2019 Feb 7;13(2):e0007138. doi: 10.1371/journal.pntd.0007138. eCollection 2019 Feb.


Sounds Impossible, but It's Knot.

Smith LE, Heath DR, Riess ML.

Anesthesiology. 2019 May;130(5):824. doi: 10.1097/ALN.0000000000002585. No abstract available.


Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on stunting and anaemia among HIV-exposed children in rural Zimbabwe: a cluster-randomised controlled trial.

Prendergast AJ, Chasekwa B, Evans C, Mutasa K, Mbuya MNN, Stoltzfus RJ, Smith LE, Majo FD, Tavengwa NV, Mutasa B, Mangwadu GT, Chasokela CM, Chigumira A, Moulton LH, Ntozini R, Humphrey JH; SHINE Trial Team.

Lancet Child Adolesc Health. 2019 Feb;3(2):77-90. doi: 10.1016/S2352-4642(18)30340-7. Epub 2018 Dec 18.


Review shows that donor milk does not promote the growth and development of preterm infants as well as maternal milk.

Hård AL, Nilsson AK, Lund AM, Hansen-Pupp I, Smith LEH, Hellström A.

Acta Paediatr. 2019 Jun;108(6):998-1007. doi: 10.1111/apa.14702. Epub 2019 Jan 25. Review.


Independent and combined effects of improved water, sanitation, and hygiene, and improved complementary feeding, on child stunting and anaemia in rural Zimbabwe: a cluster-randomised trial.

Humphrey JH, Mbuya MNN, Ntozini R, Moulton LH, Stoltzfus RJ, Tavengwa NV, Mutasa K, Majo F, Mutasa B, Mangwadu G, Chasokela CM, Chigumira A, Chasekwa B, Smith LE, Tielsch JM, Jones AD, Manges AR, Maluccio JA, Prendergast AJ; Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial Team.

Lancet Glob Health. 2019 Jan;7(1):e132-e147. doi: 10.1016/S2214-109X(18)30374-7.


Development of a Retinopathy of Prematurity Activity Scale and Clinical Outcome Measures for Use in Clinical Trials.

Smith LEH, Hellström A, Stahl A, Fielder A, Chambers W, Moseley J, Toth C, Wallace D, Darlow BA, Aranda JV, Hallberg B, Davis JM; Retinopathy of Prematurity Workgroup of the International Neonatal Consortium.

JAMA Ophthalmol. 2018 Dec 13. doi: 10.1001/jamaophthalmol.2018.5984. [Epub ahead of print]


rhIGF-1/rhIGFBP-3 in Preterm Infants: A Phase 2 Randomized Controlled Trial.

Ley D, Hallberg B, Hansen-Pupp I, Dani C, Ramenghi LA, Marlow N, Beardsall K, Bhatti F, Dunger D, Higginson JD, Mahaveer A, Mezu-Ndubuisi OJ, Reynolds P, Giannantonio C, van Weissenbruch M, Barton N, Tocoian A, Hamdani M, Jochim E, Mangili A, Chung JK, Turner MA, Smith LEH, Hellström A; study team.

J Pediatr. 2019 Mar;206:56-65.e8. doi: 10.1016/j.jpeds.2018.10.033. Epub 2018 Nov 22.


Association of Somatic GNAQ Mutation With Capillary Malformations in a Case of Choroidal Hemangioma.

Bichsel CA, Goss J, Alomari M, Alexandrescu S, Robb R, Smith LE, Hochman M, Greene A, Bischoff J.

JAMA Ophthalmol. 2019 Jan 1;137(1):91-95. doi: 10.1001/jamaophthalmol.2018.5141.


Erythropoietin serum levels, versus anaemia as risk factors for severe retinopathy of prematurity.

Lundgren P, Hellgren G, Pivodic A, Sävman K, Smith LEH, Hellström A.

Pediatr Res. 2018 Sep 18. doi: 10.1038/s41390-018-0186-6. [Epub ahead of print]


Thrombocytopenia is associated with severe retinopathy of prematurity.

Cakir B, Liegl R, Hellgren G, Lundgren P, Sun Y, Klevebro S, Löfqvist C, Mannheimer C, Cho S, Poblete A, Duran R, Hallberg B, Canas J, Lorenz V, Liu ZJ, Sola-Visner MC, Smith LE, Hellström A.

JCI Insight. 2018 Oct 4;3(19). pii: 99448. doi: 10.1172/jci.insight.99448.


Retinal Vasculature in Development and Diseases.

Sun Y, Smith LEH.

Annu Rev Vis Sci. 2018 Sep 15;4:101-122. doi: 10.1146/annurev-vision-091517-034018. Review.


"Click" Chemistry for Medicine and Biology.

Pokorski JK, Smith LE.

Mol Pharm. 2018 Aug 6;15(8):2891. doi: 10.1021/acs.molpharmaceut.8b00743. No abstract available.


Measuring wealth in rural communities: Lessons from the Sanitation, Hygiene, Infant Nutrition Efficacy (SHINE) trial.

Chasekwa B, Maluccio JA, Ntozini R, Moulton LH, Wu F, Smith LE, Matare CR, Stoltzfus RJ, Mbuya MNN, Tielsch JM, Martin SL, Jones AD, Humphrey JH, Fielding K; SHINE Trial Team.

PLoS One. 2018 Jun 28;13(6):e0199393. doi: 10.1371/journal.pone.0199393. eCollection 2018.


A Dosing Study of Bevacizumab for Retinopathy of Prematurity: Late Recurrences and Additional Treatments.

Wallace DK, Dean TW, Hartnett ME, Kong L, Smith LE, Hubbard GB, McGregor ML, Jordan CO, Mantagos IS, Bell EF, Kraker RT; Pediatric Eye Disease Investigator Group.

Ophthalmology. 2018 Dec;125(12):1961-1966. doi: 10.1016/j.ophtha.2018.05.001. Epub 2018 Jun 7.


Convergence and Divergence in Statistical and Programmatic Approaches to Address Child Stunting and Wasting.

Smith LE.

J Nutr. 2018 Jun 1;148(6):823-824. doi: 10.1093/jn/nxy098. No abstract available.


Parental Expectation of Side Effects Following Vaccination Is Self-fulfilling: A Prospective Cohort Study.

Smith LE, Weinman J, Amlôt R, Yiend J, Rubin GJ.

Ann Behav Med. 2019 Mar 1;53(3):267-282. doi: 10.1093/abm/kay040.


Plastic ingestion by Scyliorhinus canicula trawl captured in the North Sea.

Smith LE.

Mar Pollut Bull. 2018 May;130:6-7. doi: 10.1016/j.marpolbul.2018.03.001. Epub 2018 Mar 7.


A thumbwheel mechanism for APOA1 activation of LCAT activity in HDL.

Cooke AL, Morris J, Melchior JT, Street SE, Jerome WG, Huang R, Herr AB, Smith LE, Segrest JP, Remaley AT, Shah AS, Thompson TB, Davidson WS.

J Lipid Res. 2018 Jul;59(7):1244-1255. doi: 10.1194/jlr.M085332. Epub 2018 May 17.


Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 Aug;21(3):425-532. doi: 10.1007/s10456-018-9613-x. Review.


Influence of Human Milk and Parenteral Lipid Emulsions on Serum Fatty Acid Profiles in Extremely Preterm Infants.

Nilsson AK, Löfqvist C, Najm S, Hellgren G, Sävman K, Andersson MX, Smith LEH, Hellström A.

JPEN J Parenter Enteral Nutr. 2019 Jan;43(1):152-161. doi: 10.1002/jpen.1172. Epub 2018 Apr 21.


Relation of Retinopathy of Prematurity to Brain Volumes at Term Equivalent Age and Developmental Outcome at 2 Years of Corrected Age in Very Preterm Infants.

Sveinsdóttir K, Ley D, Hövel H, Fellman V, Hüppi PS, Smith LEH, Hellström A, Hansen Pupp I.

Neonatology. 2018;114(1):46-52. doi: 10.1159/000487847. Epub 2018 Apr 12.


Racial and Ethnic Disparities and Bias in the Evaluation and Reporting of Abusive Head Trauma.

Hymel KP, Laskey AL, Crowell KR, Wang M, Armijo-Garcia V, Frazier TN, Tieves KS, Foster R, Weeks K; Pediatric Brain Injury Research Network (PediBIRN) Investigators.

J Pediatr. 2018 Jul;198:137-143.e1. doi: 10.1016/j.jpeds.2018.01.048. Epub 2018 Mar 29.


Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice.

Fu Z, Wang Z, Liu CH, Gong Y, Cakir B, Liegl R, Sun Y, Meng SS, Burnim SB, Arellano I, Moran E, Duran R, Poblete A, Cho SS, Talukdar S, Akula JD, Hellström A, Smith LEH.

Diabetes. 2018 May;67(5):974-985. doi: 10.2337/db17-0830. Epub 2018 Feb 27.


Long-chain polyunsaturated fatty acids decline rapidly in milk from mothers delivering extremely preterm indicating the need for supplementation.

Nilsson AK, Löfqvist C, Najm S, Hellgren G, Sävman K, Andersson MX, Smith LEH, Hellström A.

Acta Paediatr. 2018 Jun;107(6):1020-1027. doi: 10.1111/apa.14275. Epub 2018 Mar 13.


Association of Retinopathy of Prematurity With Low Levels of Arachidonic Acid: A Secondary Analysis of a Randomized Clinical Trial.

Löfqvist CA, Najm S, Hellgren G, Engström E, Sävman K, Nilsson AK, Andersson MX, Hård AL, Smith LEH, Hellström A.

JAMA Ophthalmol. 2018 Mar 1;136(3):271-277. doi: 10.1001/jamaophthalmol.2017.6658.


Comparing Alternative Ranibizumab Dosages for Safety and Efficacy in Retinopathy of Prematurity: A Randomized Clinical Trial.

Stahl A, Krohne TU, Eter N, Oberacher-Velten I, Guthoff R, Meltendorf S, Ehrt O, Aisenbrey S, Roider J, Gerding H, Jandeck C, Smith LEH, Walz JM; Comparing Alternative Ranibizumab Dosages for Safety and Efficacy in Retinopathy of Prematurity (CARE-ROP) Study Group.

JAMA Pediatr. 2018 Mar 1;172(3):278-286. doi: 10.1001/jamapediatrics.2017.4838.


A general approach to risk modeling using partial surrogate markers with application to perioperative acute kidney injury.

Smith DK, Smith LE, Billings FT 4th, Blume JD.

Diagn Progn Res. 2017 Dec 28;1:21. doi: 10.1186/s41512-017-0022-1. eCollection 2017.


Increased postnatal concentrations of pro-inflammatory cytokines are associated with reduced IGF-I levels and retinopathy of prematurity.

Hellgren G, Löfqvist C, Hansen-Pupp I, Gram M, Smith LE, Ley D, Hellström A.

Growth Horm IGF Res. 2018 Apr;39:19-24. doi: 10.1016/j.ghir.2017.11.006. Epub 2017 Nov 27.


Cell sheets in cell therapies.

Kirby GTS, Michelmore A, Smith LE, Whittle JD, Short RD.

Cytotherapy. 2018 Feb;20(2):169-180. doi: 10.1016/j.jcyt.2017.11.004. Epub 2017 Dec 15. Review.


Duration of anaemia during the first week of life is an independent risk factor for retinopathy of prematurity.

Lundgren P, Athikarisamy SE, Patole S, Lam GC, Smith LE, Simmer K.

Acta Paediatr. 2018 May;107(5):759-766. doi: 10.1111/apa.14187. Epub 2018 Jan 11.


High-Density Lipoprotein Cholesterol Concentration and Acute Kidney Injury After Cardiac Surgery.

Smith LE, Smith DK, Blume JD, Linton MF, Billings FT 4th.

J Am Heart Assoc. 2017 Dec 9;6(12). pii: e006975. doi: 10.1161/JAHA.117.006975.


PPARα is essential for retinal lipid metabolism and neuronal survival.

Pearsall EA, Cheng R, Zhou K, Takahashi Y, Matlock HG, Vadvalkar SS, Shin Y, Fredrick TW, Gantner ML, Meng S, Fu Z, Gong Y, Kinter M, Humphries KM, Szweda LI, Smith LEH, Ma JX.

BMC Biol. 2017 Nov 28;15(1):113. doi: 10.1186/s12915-017-0451-x.


Photoreceptor glucose metabolism determines normal retinal vascular growth.

Fu Z, Löfqvist CA, Liegl R, Wang Z, Sun Y, Gong Y, Liu CH, Meng SS, Burnim SB, Arellano I, Chouinard MT, Duran R, Poblete A, Cho SS, Akula JD, Kinter M, Ley D, Pupp IH, Talukdar S, Hellström A, Smith LE.

EMBO Mol Med. 2018 Jan;10(1):76-90. doi: 10.15252/emmm.201707966.


Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism.

Joyal JS, Gantner ML, Smith LEH.

Prog Retin Eye Res. 2018 May;64:131-156. doi: 10.1016/j.preteyeres.2017.11.002. Epub 2017 Nov 22. Review. No abstract available.


Effects of a lipid emulsion containing fish oil on polyunsaturated fatty acid profiles, growth and morbidities in extremely premature infants: A randomized controlled trial.

Najm S, Löfqvist C, Hellgren G, Engström E, Lundgren P, Hård AL, Lapillonne A, Sävman K, Nilsson AK, Andersson MX, Smith LEH, Hellström A.

Clin Nutr ESPEN. 2017 Aug;20:17-23. doi: 10.1016/j.clnesp.2017.04.004. Epub 2017 May 3.


A systematic review of factors affecting vaccine uptake in young children.

Smith LE, Amlôt R, Weinman J, Yiend J, Rubin GJ.

Vaccine. 2017 Oct 27;35(45):6059-6069. doi: 10.1016/j.vaccine.2017.09.046. Epub 2017 Sep 30. Review.


IGF-1 as a Drug for Preterm Infants: A Step-Wise Clinical Development.

Hellstrom A, Ley D, Hallberg B, Lofqvist C, Hansen-Pupp I, Ramenghi LA, Borg J, Smith LEH, Hard AL.

Curr Pharm Des. 2017;23(38):5964-5970. doi: 10.2174/1381612823666171002114545.


Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis.

Xie YL, Chakravorty S, Armstrong DT, Hall SL, Via LE, Song T, Yuan X, Mo X, Zhu H, Xu P, Gao Q, Lee M, Lee J, Smith LE, Chen RY, Joh JS, Cho Y, Liu X, Ruan X, Liang L, Dharan N, Cho SN, Barry CE 3rd, Ellner JJ, Dorman SE, Alland D.

N Engl J Med. 2017 Sep 14;377(11):1043-1054. doi: 10.1056/NEJMoa1614915.


Implementing higher oxygen saturation targets reduced the impact of poor weight gain as a predictor for retinopathy of prematurity.

Lundgren P, Hård AL, Wilde Å, Löfqvist C, Smith LEH, Hellström A.

Acta Paediatr. 2018 May;107(5):767-773. doi: 10.1111/apa.14049. Epub 2017 Sep 20.


VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis.

Chen J, Fu Y, Day DS, Sun Y, Wang S, Liang X, Gu F, Zhang F, Stevens SM, Zhou P, Li K, Zhang Y, Lin RZ, Smith LEH, Zhang J, Sun K, Melero-Martin JM, Han Z, Park PJ, Zhang B, Pu WT.

Nat Commun. 2017 Aug 29;8(1):383. doi: 10.1038/s41467-017-00405-x.


Prognostic variables and scores identifying the end of life in COPD: a systematic review.

Smith LE, Moore E, Ali I, Smeeth L, Stone P, Quint JK.

Int J Chron Obstruct Pulmon Dis. 2017 Jul 31;12:2239-2256. doi: 10.2147/COPD.S137868. eCollection 2017. Review.


Acute GI bleed due to leiomyoma of the jejunum: a case report.

Smith LE.

J Surg Case Rep. 2017 Jul 28;2017(7):rjx138. doi: 10.1093/jscr/rjx138. eCollection 2017 Jul.


Adiponectin Mediates Dietary Omega-3 Long-Chain Polyunsaturated Fatty Acid Protection Against Choroidal Neovascularization in Mice.

Fu Z, Liegl R, Wang Z, Gong Y, Liu CH, Sun Y, Cakir B, Burnim SB, Meng SS, Löfqvist C, SanGiovanni JP, Hellström A, Smith LEH.

Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3862-3870. doi: 10.1167/iovs.17-21796.


Factors associated with sustained community employment among adults with autism and co-occurring intellectual disability.

Chan W, Smith LE, Hong J, Greenberg JS, Lounds Taylor J, Mailick MR.

Autism. 2018 Oct;22(7):794-803. doi: 10.1177/1362361317703760. Epub 2017 Jul 9.


Validating the social responsiveness scale for adults with autism.

Chan W, Smith LE, Hong J, Greenberg JS, Mailick MR.

Autism Res. 2017 Oct;10(10):1663-1671. doi: 10.1002/aur.1813. Epub 2017 Jun 22.


Cerebellar Exposure to Cell-Free Hemoglobin Following Preterm Intraventricular Hemorrhage: Causal in Cerebellar Damage?

Agyemang AA, Sveinsdóttir K, Vallius S, Sveinsdóttir S, Bruschettini M, Romantsik O, Hellström A, Smith LEH, Ohlsson L, Holmqvist B, Gram M, Ley D.

Transl Stroke Res. 2017 Jun 10. doi: 10.1007/s12975-017-0539-1. [Epub ahead of print]


Determinants of recent aflatoxin exposure among pregnant women in rural Zimbabwe.

Smith LE, Mbuya MNN, Prendergast AJ, Turner PC, Ruboko S, Humphrey JH, Nelson RJ, Chigumira A, Kembo G, Stoltzfus RJ.

Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201601049. Epub 2017 Jul 19.


Retinopathy of prematurity: the need for prevention.

Liegl R, Hellström A, Smith LE.

Eye Brain. 2016 May 20;8:91-102. doi: 10.2147/EB.S99038. eCollection 2016. Review.

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