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Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors.

Powers RK, Culp-Hill R, Ludwig MP, Smith KP, Waugh KA, Minter R, Tuttle KD, Lewis HC, Rachubinski AL, Granrath RE, Carmona-Iragui M, Wilkerson RB, Kahn DE, Joshi M, Lleó A, Blesa R, Fortea J, D'Alessandro A, Costello JC, Sullivan KD, Espinosa JM.

Nat Commun. 2019 Oct 18;10(1):4766. doi: 10.1038/s41467-019-12739-9.


Bringing antimicrobial susceptibility testing for new drugs into the clinical laboratory: removing obstacles in our fight against multidrug-resistant pathogens.

Kirby JE, Brennan-Krohn T, Smith KP.

J Clin Microbiol. 2019 Sep 18. pii: JCM.01270-19. doi: 10.1128/JCM.01270-19. [Epub ahead of print]


Rapid Susceptibility Testing Methods.

Smith KP, Kirby JE.

Clin Lab Med. 2019 Sep;39(3):333-344. doi: 10.1016/j.cll.2019.04.001. Epub 2019 Jun 12. Review.


Multi-trait Improvement by Predicting Genetic Correlations in Breeding Crosses.

Neyhart JL, Lorenz AJ, Smith KP.

G3 (Bethesda). 2019 Oct 7;9(10):3153-3165. doi: 10.1534/g3.119.400406.


Development of a Multiparent Population for Genetic Mapping and Allele Discovery in Six-Row Barley.

Hemshrot A, Poets AM, Tyagi P, Lei L, Carter CK, Hirsch CN, Li L, Brown-Guedira G, Morrell PL, Muehlbauer GJ, Smith KP.

Genetics. 2019 Oct;213(2):595-613. doi: 10.1534/genetics.119.302046. Epub 2019 Jul 29.


Emergency department-based peer support for opioid use disorder: Emergent functions and forms.

McGuire AB, Powell KG, Treitler PC, Wagner KD, Smith KP, Cooperman N, Robinson L, Carter J, Ray B, Watson DP.

J Subst Abuse Treat. 2019 Jun 19. pii: S0740-5472(19)30082-0. doi: 10.1016/j.jsat.2019.06.013. [Epub ahead of print]


A Whole-Cell Screen for Adjunctive and Direct Antimicrobials Active against Carbapenem-Resistant Enterobacteriaceae.

Smith KP, Dowgiallo MG, Chiaraviglio L, Parvatkar P, Kim C, Manetsch R, Kirby JE.

SLAS Discov. 2019 Sep;24(8):842-853. doi: 10.1177/2472555219859592. Epub 2019 Jul 3.


Quantifying cereal crop movement through hemispherical video analysis of agricultural plots.

Susko AQ, Marchetto P, Jo Heuschele D, Smith KP.

Plant Methods. 2019 May 24;15:55. doi: 10.1186/s13007-019-0437-5. eCollection 2019.


"Another tool for the tool box? I'll take it!": Feasibility and acceptability of mobile recovery outreach teams (MROT) for opioid overdose patients in the emergency room.

Wagner KD, Oman RF, Smith KP, Harding RW, Dawkins AD, Lu M, Woodard S, Berry MN, Roget NA.

J Subst Abuse Treat. 2019 May 1. pii: S0740-5472(19)30062-5. doi: 10.1016/j.jsat.2019.04.011. [Epub ahead of print]


Complete Genome Sequences of 12 B1 Cluster Mycobacteriophages, Gareth, JangoPhett, Kailash, MichaelPhcott, PhenghisKhan, Phleuron, Phergie, PhrankReynolds, PhrodoBaggins, Phunky, Vaticameos, and Virapocalypse.

Apellido KA, Balchander D, Erlich MC, Gocal JK, Gocal WA, Haile S, Kang AK, Koduri S, Natrajan M, Parikh AA, Tata RK, Walor TA, Wong BM, Nako S, Tran T, Islam E, Mammen MP; Drexel University SEA-PHAGES annotators 2016; Drexel University SEA-PHAGES annotators 2017; Drexel University SEA-PHAGES annotators 2018, Ball SL, Bollivar DW, Butela KA, Pope WH, McDonald MT, Tang CA, Dalia RR, Smith KPW, Little JL, Moyer AE, Gurney SMR.

Microbiol Resour Announc. 2019 Feb 21;8(8). pii: e01387-18. doi: 10.1128/MRA.01387-18. eCollection 2019 Feb.


Evaluation of apramycin against spectinomycin-resistant and -susceptible strains of Neisseria gonorrhoeae.

Riedel S, Vijayakumar D, Berg G, Kang AD, Smith KP, Kirby JE.

J Antimicrob Chemother. 2019 May 1;74(5):1311-1316. doi: 10.1093/jac/dkz012.


Trypanosoma brucei PRMT1 Is a Nucleic Acid Binding Protein with a Role in Energy Metabolism and the Starvation Stress Response.

Kafková L, Tu C, Pazzo KL, Smith KP, Debler EW, Paul KS, Qu J, Read LK.

MBio. 2018 Dec 18;9(6). pii: e02430-18. doi: 10.1128/mBio.02430-18.


QTL Mapping of Fusarium Head Blight and Correlated Agromorphological Traits in an Elite Barley Cultivar Rasmusson.

Huang Y, Haas M, Heinen S, Steffenson BJ, Smith KP, Muehlbauer GJ.

Front Plant Sci. 2018 Aug 28;9:1260. doi: 10.3389/fpls.2018.01260. eCollection 2018.


Cdt1 stabilizes kinetochore-microtubule attachments via an Aurora B kinase-dependent mechanism.

Agarwal S, Smith KP, Zhou Y, Suzuki A, McKenney RJ, Varma D.

J Cell Biol. 2018 Oct 1;217(10):3446-3463. doi: 10.1083/jcb.201705127. Epub 2018 Aug 28.


Effects of Interrupting Sedentary Behavior With Short Bouts of Moderate Physical Activity on Glucose Tolerance in Children With Overweight and Obesity: A Randomized Crossover Trial.

Broadney MM, Belcher BR, Berrigan DA, Brychta RJ, Tigner IL Jr, Shareef F, Papachristopoulou A, Hattenbach JD, Davis EK, Brady SM, Bernstein SB, Courville AB, Drinkard BE, Smith KP, Rosing DR, Wolters PL, Chen KY, Yanovski JA.

Diabetes Care. 2018 Oct;41(10):2220-2228. doi: 10.2337/dc18-0774. Epub 2018 Aug 6.


Evaluation of apramycin activity against methicillin-resistant, methicillin-sensitive, and vancomycin-intermediate Staphylococcus aureus clinical isolates.

Truelson KA, Brennan-Krohn T, Smith KP, Kirby JE.

Diagn Microbiol Infect Dis. 2018 Oct;92(2):168-171. doi: 10.1016/j.diagmicrobio.2018.05.018. Epub 2018 May 29.


A home-based mentored vegetable gardening intervention demonstrates feasibility and improvements in physical activity and performance among breast cancer survivors.

Bail JR, Frugé AD, Cases MG, De Los Santos JF, Locher JL, Smith KP, Cantor AB, Cohen HJ, Demark-Wahnefried W.

Cancer. 2018 Aug;124(16):3427-3435. doi: 10.1002/cncr.31559. Epub 2018 Jun 22.


The Inoculum Effect in the Era of Multidrug Resistance: Minor Differences in Inoculum Have Dramatic Effect on MIC Determination.

Smith KP, Kirby JE.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00433-18. doi: 10.1128/AAC.00433-18. Print 2018 Aug.


Complete Genome Sequence of Cluster J Mycobacteriophage Superphikiman.

Pradhan P, Nako S, Tran T, Aluri LS, Anandarajan D, Betini N, Bhatt SD, Chengalvala S, Cox NE, Delvadia BP, Desai AS, Devaney AM, Doyle BK, Edgerton AO, Erlich MC, Fitzpatrick KC, Gajjar EA, Ganguly A, Gill RS, Good PM, Gupta N, Haddad LM, Han EJ, Jain S, Jiang A, Jurgielewicz AD, Kainth DK, Karam JM, Kodavatiganti M, Kriete SJ, MacDonald CE, Maret JP, Mathew AE, Natrajan M, Nishu NM, Patel N, Patel PD, Patel S, Patra K, Rai KK, Sarkar A, Shah P, Tata RK, Tawfik AH, Thuremella BT, Toma J, Veera S, Vemulapalli VK, Vidas TV, Vieira KS, Vijayakumar G, Walor TA, White CR, Wong BM, Zhao SL, Bollivar DW, McDonald MT, Dalia RR, Smith KPW, Little JL, Gurney SMR.

Genome Announc. 2018 Feb 1;6(5). pii: e01538-17. doi: 10.1128/genomeA.01538-17.


Pharmacy Residency School-wide Match Rates and Modifiable Predictors in ACPE-accredited Colleges and Schools of Pharmacy.

Whittaker A, Smith KP, Shan G.

Am J Pharm Educ. 2017 Dec;81(10):6109. doi: 10.5688/ajpe6109.


Efficacy of Apramycin against Multidrug-Resistant Acinetobacter baumannii in the Murine Neutropenic Thigh Model.

Kang AD, Smith KP, Berg AH, Truelson KA, Eliopoulos GM, McCoy C, Kirby JE.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02585-17. doi: 10.1128/AAC.02585-17. Print 2018 Apr.


Pilot Randomized Controlled Trial of a Home Vegetable Gardening Intervention among Older Cancer Survivors Shows Feasibility, Satisfaction, and Promise in Improving Vegetable and Fruit Consumption, Reassurance of Worth, and the Trajectory of Central Adiposity.

Demark-Wahnefried W, Cases MG, Cantor AB, Frugé AD, Smith KP, Locher J, Cohen HJ, Tsuruta Y, Daniel M, Kala R, De Los Santos JF.

J Acad Nutr Diet. 2018 Apr;118(4):689-704. doi: 10.1016/j.jand.2017.11.001. Epub 2018 Jan 2.


Automated Interpretation of Blood Culture Gram Stains by Use of a Deep Convolutional Neural Network.

Smith KP, Kang AD, Kirby JE.

J Clin Microbiol. 2018 Feb 22;56(3). pii: e01521-17. doi: 10.1128/JCM.01521-17. Print 2018 Mar.


Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation.

Sullivan KD, Evans D, Pandey A, Hraha TH, Smith KP, Markham N, Rachubinski AL, Wolter-Warmerdam K, Hickey F, Espinosa JM, Blumenthal T.

Sci Rep. 2017 Nov 1;7(1):14818. doi: 10.1038/s41598-017-13858-3.


Screening for synergistic activity of antimicrobial combinations against carbapenem-resistant Enterobacteriaceae using inkjet printer-based technology.

Brennan-Krohn T, Truelson KA, Smith KP, Kirby JE.

J Antimicrob Chemother. 2017 Oct 1;72(10):2775-2781. doi: 10.1093/jac/dkx241.


Development of MAST: A Microscopy-Based Antimicrobial Susceptibility Testing Platform.

Smith KP, Richmond DL, Brennan-Krohn T, Elliott HL, Kirby JE.

SLAS Technol. 2017 Dec;22(6):662-674. doi: 10.1177/2472630317727721. Epub 2017 Aug 24.


Activity of minocycline against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae clinical isolates, with comparison to doxycycline and tigecycline.

Chen A, Smith KP, Whitfield BA, Zucchi PC, Lasco TM, Bias TE, Kirby JE, Hirsch EB.

Diagn Microbiol Infect Dis. 2017 Aug;88(4):365-367. doi: 10.1016/j.diagmicrobio.2017.05.004. Epub 2017 May 11.


The Poisoned Well: Enhancing the Predictive Value of Antimicrobial Susceptibility Testing in the Era of Multidrug Resistance.

Brennan-Krohn T, Smith KP, Kirby JE.

J Clin Microbiol. 2017 Aug;55(8):2304-2308. doi: 10.1128/JCM.00511-17. Epub 2017 May 3.


Invitro Apramycin Activity against multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa.

Kang AD, Smith KP, Eliopoulos GM, Berg AH, McCoy C, Kirby JE.

Diagn Microbiol Infect Dis. 2017 Jun;88(2):188-191. doi: 10.1016/j.diagmicrobio.2017.03.006. Epub 2017 Mar 16.


Evaluating Methods of Updating Training Data in Long-Term Genomewide Selection.

Neyhart JL, Tiede T, Lorenz AJ, Smith KP.

G3 (Bethesda). 2017 May 5;7(5):1499-1510. doi: 10.1534/g3.117.040550.


Improved Accuracy of Cefepime Susceptibility Testing for Extended-Spectrum-Beta-Lactamase-Producing Enterobacteriaceae with an On-Demand Digital Dispensing Method.

Smith KP, Brennan-Krohn T, Weir S, Kirby JE.

J Clin Microbiol. 2017 Feb;55(2):470-478. doi: 10.1128/JCM.02128-16. Epub 2016 Nov 30.


Evaluation of apramycin activity against carbapenem-resistant and -susceptible strains of Enterobacteriaceae.

Smith KP, Kirby JE.

Diagn Microbiol Infect Dis. 2016 Dec;86(4):439-441. doi: 10.1016/j.diagmicrobio.2016.09.002. Epub 2016 Sep 8.


How inkjet printing technology can defeat multidrug-resistant pathogens.

Smith KP, Kirby JE.

Future Microbiol. 2016 Oct;11:1375-1377. Epub 2016 Oct 27. No abstract available.


Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.

Klosowiak JL, Park S, Smith KP, French ME, Focia PJ, Freymann DM, Rice SE.

Sci Rep. 2016 Sep 8;6:33019. doi: 10.1038/srep33019.


Detailed methods of two home-based vegetable gardening intervention trials to improve diet, physical activity, and quality of life in two different populations of cancer survivors.

Cases MG, Frugé AD, De Los Santos JF, Locher JL, Cantor AB, Smith KP, Glover TA, Cohen HJ, Daniel M, Morrow CD, Moellering DR, Demark-Wahnefried W.

Contemp Clin Trials. 2016 Sep;50:201-12. doi: 10.1016/j.cct.2016.08.014. Epub 2016 Aug 23.


Genome-Wide Association Study of Spot Form of Net Blotch Resistance in the Upper Midwest Barley Breeding Programs.

Burlakoti RR, Gyawali S, Chao S, Smith KP, Horsley RD, Cooper B, Muehlbauer GJ, Neate SM.

Phytopathology. 2017 Jan;107(1):100-108. Epub 2016 Oct 11.


Trisomy 21 consistently activates the interferon response.

Sullivan KD, Lewis HC, Hill AA, Pandey A, Jackson LP, Cabral JM, Smith KP, Liggett LA, Gomez EB, Galbraith MD, DeGregori J, Espinosa JM.

Elife. 2016 Jul 29;5. pii: e16220. doi: 10.7554/eLife.16220.


Verification of an Automated, Digital Dispensing Platform for At-Will Broth Microdilution-Based Antimicrobial Susceptibility Testing.

Smith KP, Kirby JE.

J Clin Microbiol. 2016 Sep;54(9):2288-93. doi: 10.1128/JCM.00932-16. Epub 2016 Jun 22.


The Role of Deleterious Substitutions in Crop Genomes.

Kono TJ, Fu F, Mohammadi M, Hoffman PJ, Liu C, Stupar RM, Smith KP, Tiffin P, Fay JC, Morrell PL.

Mol Biol Evol. 2016 Sep;33(9):2307-17. doi: 10.1093/molbev/msw102. Epub 2016 Jun 14.


Impact of a bronchial genomic classifier on clinical decision making in patients undergoing diagnostic evaluation for lung cancer.

Ferguson JS, Van Wert R, Choi Y, Rosenbluth MJ, Smith KP, Huang J, Spira A.

BMC Pulm Med. 2016 May 17;16(1):66. doi: 10.1186/s12890-016-0217-1.


Development and Genetic Characterization of an Advanced Backcross-Nested Association Mapping (AB-NAM) Population of Wild × Cultivated Barley.

Nice LM, Steffenson BJ, Brown-Guedira GL, Akhunov ED, Liu C, Kono TJ, Morrell PL, Blake TK, Horsley RD, Smith KP, Muehlbauer GJ.

Genetics. 2016 Jul;203(3):1453-67. doi: 10.1534/genetics.116.190736. Epub 2016 May 10.


Analytical performance of a bronchial genomic classifier.

Hu Z, Whitney D, Anderson JR, Cao M, Ho C, Choi Y, Huang J, Frink R, Smith KP, Monroe R, Kennedy GC, Walsh PS.

BMC Cancer. 2016 Feb 26;16:161. doi: 10.1186/s12885-016-2153-0.


Inner-membrane protein MorC is involved in fimbriae production and biofilm formation in Aggregatibacter actinomycetemcomitans.

Smith KP, Ruiz T, Mintz KP.

Microbiology. 2016 Mar;162(3):513-25. doi: 10.1099/mic.0.000246. Epub 2016 Jan 20.


The Effects of Both Recent and Long-Term Selection and Genetic Drift Are Readily Evident in North American Barley Breeding Populations.

Poets AM, Mohammadi M, Seth K, Wang H, Kono TJ, Fang Z, Muehlbauer GJ, Smith KP, Morrell PL.

G3 (Bethesda). 2015 Dec 29;6(3):609-22. doi: 10.1534/g3.115.024349.


Effects of Interrupting Children's Sedentary Behaviors With Activity on Metabolic Function: A Randomized Trial.

Belcher BR, Berrigan D, Papachristopoulou A, Brady SM, Bernstein SB, Brychta RJ, Hattenbach JD, Tigner IL Jr, Courville AB, Drinkard BE, Smith KP, Rosing DR, Wolters PL, Chen KY, Yanovski JA.

J Clin Endocrinol Metab. 2015 Oct;100(10):3735-43. doi: 10.1210/jc.2015-2803. Epub 2015 Aug 27.


Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley.

Graebner RC, Wise M, Cuesta-Marcos A, Geniza M, Blake T, Blake VC, Butler J, Chao S, Hole DJ, Horsley R, Jaiswal P, Obert D, Smith KP, Ullrich S, Hayes PM.

PLoS One. 2015 Jul 24;10(7):e0133767. doi: 10.1371/journal.pone.0133767. eCollection 2015.


The conserved carboxyl domain of MorC, an inner membrane protein of Aggregatibacter actinomycetemcomitans, is essential for membrane function.

Smith KP, Voogt RD, Ruiz T, Mintz KP.

Mol Oral Microbiol. 2016 Feb;31(1):43-58. doi: 10.1111/omi.12120. Epub 2015 Sep 15.


Mercury-impacted scrap metal: Source and nature of the mercury.

Finster ME, Raymond MR, Scofield MA, Smith KP.

J Environ Manage. 2015 Sep 15;161:303-308. doi: 10.1016/j.jenvman.2015.05.041. Epub 2015 Jul 18. Review.


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