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Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small-cell lung carcinoma: a proposal for quantitative immune-related pathologic response criteria (irPRC).

Cottrell TR, Thompson ED, Forde PM, Stein JE, Duffield AS, Anagnostou V, Rekhtman N, Anders RA, Cuda JD, Illei PB, Gabrielson E, Askin FB, Niknafs N, Smith KN, Velez MJ, Sauter JL, Isbell JM, Jones DR, Battafarano RJ, Yang SC, Danilova L, Wolchok JD, Topalian SL, Velculescu VE, Pardoll DM, Brahmer JR, Hellmann MD, Chaft JE, Cimino-Mathews A, Taube JM.

Ann Oncol. 2018 Aug 1;29(8):1853-1860. doi: 10.1093/annonc/mdy218.


The Mutation-Associated Neoantigen Functional Expansion of Specific T Cells (MANAFEST) Assay: A Sensitive Platform for Monitoring Antitumor Immunity.

Danilova L, Anagnostou V, Caushi JX, Sidhom JW, Guo H, Chan HY, Suri P, Tam A, Zhang J, Asmar ME, Marrone KA, Naidoo J, Brahmer JR, Forde PM, Baras AS, Cope L, Velculescu VE, Pardoll DM, Housseau F, Smith KN.

Cancer Immunol Res. 2018 Aug;6(8):888-899. doi: 10.1158/2326-6066.CIR-18-0129. Epub 2018 Jun 12.


Neoadjuvant PD-1 Blockade in Resectable Lung Cancer.

Forde PM, Chaft JE, Smith KN, Anagnostou V, Cottrell TR, Hellmann MD, Zahurak M, Yang SC, Jones DR, Broderick S, Battafarano RJ, Velez MJ, Rekhtman N, Olah Z, Naidoo J, Marrone KA, Verde F, Guo H, Zhang J, Caushi JX, Chan HY, Sidhom JW, Scharpf RB, White J, Gabrielson E, Wang H, Rosner GL, Rusch V, Wolchok JD, Merghoub T, Taube JM, Velculescu VE, Topalian SL, Brahmer JR, Pardoll DM.

N Engl J Med. 2018 May 24;378(21):1976-1986. doi: 10.1056/NEJMoa1716078. Epub 2018 Apr 16.


Long-term outcomes in cancer patients who did or did not pursue fertility preservation.

Moravek MB, Confino R, Smith KN, Kazer RR, Klock SC, Lawson AK, Gradishar WJ, Pavone ME.

Fertil Steril. 2018 Feb;109(2):349-355. doi: 10.1016/j.fertnstert.2017.10.029. Epub 2018 Jan 17.


Quantifying the anti-tumor immune response in patients receiving immunotherapy.

Caushi JX, Smith KN.

Discov Med. 2017 Aug;24(130):59-68. Review.


Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.

Le DT, Durham JN, Smith KN, Wang H, Bartlett BR, Aulakh LK, Lu S, Kemberling H, Wilt C, Luber BS, Wong F, Azad NS, Rucki AA, Laheru D, Donehower R, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Greten TF, Duffy AG, Ciombor KK, Eyring AD, Lam BH, Joe A, Kang SP, Holdhoff M, Danilova L, Cope L, Meyer C, Zhou S, Goldberg RM, Armstrong DK, Bever KM, Fader AN, Taube J, Housseau F, Spetzler D, Xiao N, Pardoll DM, Papadopoulos N, Kinzler KW, Eshleman JR, Vogelstein B, Anders RA, Diaz LA Jr.

Science. 2017 Jul 28;357(6349):409-413. doi: 10.1126/science.aan6733. Epub 2017 Jun 8.


Analysis of natural product regulation of cannabinoid receptors in the treatment of human disease.

Badal S, Smith KN, Rajnarayanan R.

Pharmacol Ther. 2017 Dec;180:24-48. doi: 10.1016/j.pharmthera.2017.06.003. Epub 2017 Jun 3. Review.


Long Noncoding RNA Moderates MicroRNA Activity to Maintain Self-Renewal in Embryonic Stem Cells.

Smith KN, Starmer J, Miller SC, Sethupathy P, Magnuson T.

Stem Cell Reports. 2017 Jul 11;9(1):108-121. doi: 10.1016/j.stemcr.2017.05.005. Epub 2017 Jun 1.


Disparities in Diagnosis and Treatment of Autism in Latino and Non-Latino White Families.

Zuckerman KE, Lindly OJ, Reyes NM, Chavez AE, Macias K, Smith KN, Reynolds A.

Pediatrics. 2017 May;139(5). pii: e20163010. doi: 10.1542/peds.2016-3010.


Disparities in Counseling Female Cancer Patients for Fertility Preservation.

Lawson AK, McGuire JM, Noncent E, Olivieri JF Jr, Smith KN, Marsh EE.

J Womens Health (Larchmt). 2017 Aug;26(8):886-891. doi: 10.1089/jwh.2016.5997. Epub 2017 May 12.


Does Including Public Health Students on Interprofessional Teams Increase Attainment of Interprofessional Practice Competencies?

Duffy PA, Ronnebaum JA, Stumbo TA, Smith KN, Reimer RA.

J Am Osteopath Assoc. 2017 Apr 1;117(4):244-252. doi: 10.7556/jaoa.2017.042.


Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer.

Anagnostou V, Smith KN, Forde PM, Niknafs N, Bhattacharya R, White J, Zhang T, Adleff V, Phallen J, Wali N, Hruban C, Guthrie VB, Rodgers K, Naidoo J, Kang H, Sharfman W, Georgiades C, Verde F, Illei P, Li QK, Gabrielson E, Brock MV, Zahnow CA, Baylin SB, Scharpf RB, Brahmer JR, Karchin R, Pardoll DM, Velculescu VE.

Cancer Discov. 2017 Mar;7(3):264-276. doi: 10.1158/2159-8290.CD-16-0828. Epub 2016 Dec 28.


The impact of fertility preservation on treatment delay and progression-free survival in women with lymphoma: a single-centre experience.

Allen PB, Pavone ME, Smith KN, Kazer RR, Rademaker A, Lawson AK, Moravek MB, Confino R, Gordon LI, Winter JN.

Br J Haematol. 2018 Mar;180(6):901-904. doi: 10.1111/bjh.14466. Epub 2016 Dec 16. No abstract available.


Plasma glucose and insulin response to two oral nutrition supplements in adults with type 2 diabetes mellitus.

Huhmann MB, Smith KN, Schwartz SL, Haller SK, Irvin S, Cohen SS.

BMJ Open Diabetes Res Care. 2016 Aug 31;4(1):e000240. doi: 10.1136/bmjdrc-2016-000240. eCollection 2016.


Erratum for Smith et al., Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells.

Smith KN, Mailliard RB, Piazza PA, Fischer W, Korber BT, Fecek RJ, Ratner D, Gupta P, Mullins JI, Rinaldo CR.

MBio. 2016 Jul 12;7(4). pii: e01012-16. doi: 10.1128/mBio.01012-16. No abstract available.


Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells.

Smith KN, Mailliard RB, Piazza PA, Fischer W, Korber BT, Fecek RJ, Ratner D, Gupta P, Mullins JI, Rinaldo CR.

MBio. 2016 May 31;7(3). pii: e00473-16. doi: 10.1128/mBio.00473-16. Erratum in: MBio. 2016;7(4). pii: e01012-16. doi: 10.1128/mBio.01012-16.


The Effects of Breakfast Consumption and Composition on Metabolic Wellness with a Focus on Carbohydrate Metabolism.

Maki KC, Phillips-Eakley AK, Smith KN.

Adv Nutr. 2016 May 16;7(3):613S-21S. doi: 10.3945/an.115.010314. Print 2016 May. Review.


Documentation of Fertility Preservation Discussions for Young Adults With Cancer: Examining Compliance With Treatment Guidelines.

Salsman JM, Yanez B, Smith KN, Beaumont JL, Snyder MA, Barnes K, Clayman ML.

J Natl Compr Canc Netw. 2016 Mar;14(3):301-9.


Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis.

Housseau F, Wu S, Wick EC, Fan H, Wu X, Llosa NJ, Smith KN, Tam A, Ganguly S, Wanyiri JW, Iyadorai T, Malik AA, Roslani AC, Vadivelu JS, Van Meerbeke S, Huso DL, Pardoll DM, Sears CL.

Cancer Res. 2016 Apr 15;76(8):2115-24. doi: 10.1158/0008-5472.CAN-15-0749. Epub 2016 Feb 15.


In vitro follicle growth supports human oocyte meiotic maturation.

Xiao S, Zhang J, Romero MM, Smith KN, Shea LD, Woodruff TK.

Sci Rep. 2015 Nov 27;5:17323. doi: 10.1038/srep17323.


Alternative translation initiation codons for the plastid maturase MatK: unraveling the pseudogene misconception in the Orchidaceae.

Barthet MM, Moukarzel K, Smith KN, Patel J, Hilu KW.

BMC Evol Biol. 2015 Sep 29;15:210. doi: 10.1186/s12862-015-0491-1.


Psychological Counseling of Female Fertility Preservation Patients.

Lawson AK, Klock SC, Pavone ME, Hirshfeld-Cytron J, Smith KN, Kazer RR.

J Psychosoc Oncol. 2015;33(4):333-53. doi: 10.1080/07347332.2015.1045677. Review.


An unexpected journey: how cancer immunotherapy has paved the way for an HIV-1 cure.

Smith KN, Housseau F.

Discov Med. 2015 Mar;19(104):229-38. Review.


Programming T cell Killers for an HIV Cure: Teach the New Dogs New Tricks and Let the Sleeping Dogs Lie.

Smith KN, Mailliard RB, Rinaldo CR.

For Immunopathol Dis Therap. 2015;6(1-2):67-77. doi: 10.1615/ForumImmunDisTher.2016014160.


Prospective study of depression and anxiety in female fertility preservation and infertility patients.

Lawson AK, Klock SC, Pavone ME, Hirshfeld-Cytron J, Smith KN, Kazer RR.

Fertil Steril. 2014 Nov;102(5):1377-84. doi: 10.1016/j.fertnstert.2014.07.765. Epub 2014 Aug 22.


Dendritic cells restore CD8+ T cell reactivity to autologous HIV-1.

Smith KN, Mailliard RB, Larsen BB, Wong K, Gupta P, Mullins JI, Rinaldo CR.

J Virol. 2014 Sep 1;88(17):9976-90. doi: 10.1128/JVI.01275-14. Epub 2014 Jun 18.


The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8⁺ T cell responses.

Melhem NM, Smith KN, Huang XL, Colleton BA, Jiang W, Mailliard RB, Mullins JI, Rinaldo CR.

Virology. 2014 Feb;450-451:34-48. doi: 10.1016/j.virol.2013.10.015. Epub 2013 Dec 20.


Square Pegs, Round Hole? Ensuring Fit in the AYAO Spectrum for Adolescents and Young Adults with Genetic Risk for Cancer.

Sanford SD, O'Connor ML, Smith KN, Young AE.

J Adolesc Young Adult Oncol. 2013 Sep;2(3):130-132.


Selective induction of CTL helper rather than killer activity by natural epitope variants promotes dendritic cell-mediated HIV-1 dissemination.

Mailliard RB, Smith KN, Fecek RJ, Rappocciolo G, Nascimento EJ, Marques ET, Watkins SC, Mullins JI, Rinaldo CR.

J Immunol. 2013 Sep 1;191(5):2570-80. doi: 10.4049/jimmunol.1300373. Epub 2013 Aug 2.


Chromosome X loci and spontaneous granulosa cell tumor development in SWR mice: epigenetics and epistasis at work for an ovarian phenotype.

Dorward AM, Yaskowiak ES, Smith KN, Stanford KR, Shultz KL, Beamer WG.

Epigenetics. 2013 Feb;8(2):184-91. doi: 10.4161/epi.23399. Epub 2013 Jan 8.


Fine map of the Gct1 spontaneous ovarian granulosa cell tumor locus.

Smith KN, Halfyard SJ, Yaskowiak ES, Shultz KL, Beamer WG, Dorward AM.

Mamm Genome. 2013 Feb;24(1-2):63-71. doi: 10.1007/s00335-012-9439-6. Epub 2012 Nov 18.


Characterization of null and hypomorphic alleles of the Drosophila l(2)dtl/cdt2 gene: Larval lethality and male fertility.

Sloan RS, Swanson CI, Gavilano L, Smith KN, Malek PY, Snow-Smith M, Duronio RJ, Key SC.

Fly (Austin). 2012 Jul-Sep;6(3):173-83. doi: 10.4161/fly.20247. Epub 2012 Jun 22.


Myc orchestrates a regulatory network required for the establishment and maintenance of pluripotency.

Smith KN, Lim JM, Wells L, Dalton S.

Cell Cycle. 2011 Feb 15;10(4):592-7. Epub 2011 Feb 15.


Increased A1C among adult emergency department patients with type 2 diabetes.

Silverman RA, Arora H, Kwiatkowski TM, Graff KK, Baneman E, Kohn N, Foss Bowman C, Smith KN, Lesser ML.

Ann Emerg Med. 2011 Jun;57(6):575-81. doi: 10.1016/j.annemergmed.2010.11.016. Epub 2011 Jan 12.


Reinvigorating performance evaluation: first steps in a local health department.

Smith KN, Gunzenhauser JD, Fielding JE.

Public Health Nurs. 2010 Sep-Oct;27(5):425-32. doi: 10.1111/j.1525-1446.2010.00875.x.


Myc represses primitive endoderm differentiation in pluripotent stem cells.

Smith KN, Singh AM, Dalton S.

Cell Stem Cell. 2010 Sep 3;7(3):343-54. doi: 10.1016/j.stem.2010.06.023.


Siamangs (Hylobates syndactylus) and white-cheeked gibbons (Hylobates leucogenys) show few behavioral differences related to zoo attendance.

Smith KN, Kuhar CW.

J Appl Anim Welf Sci. 2010;13(2):154-63. doi: 10.1080/10888700903579895.


Pyruvate kinase deficiency as a cause of extreme hyperbilirubinemia in neonates from a polygamist community.

Christensen RD, Eggert LD, Baer VL, Smith KN.

J Perinatol. 2010 Mar;30(3):233-6. doi: 10.1038/jp.2009.118.


The quality improvement experience in a high-performing local health department: Los Angeles County.

Gunzenhauser JD, Eggena ZP, Fielding JE, Smith KN, Jacobson DM, Bazini-Barakat N.

J Public Health Manag Pract. 2010 Jan-Feb;16(1):39-48. doi: 10.1097/PHH.0b013e3181bedcf1.


Determination of the active site of Sphingobium chlorophenolicum 2,6-dichlorohydroquinone dioxygenase (PcpA).

Machonkin TE, Holland PL, Smith KN, Liberman JS, Dinescu A, Cundari TR, Rocks SS.

J Biol Inorg Chem. 2010 Mar;15(3):291-301. doi: 10.1007/s00775-009-0602-9.


Pup development and maternal behavior in captive Key Largo woodrats (Neotoma floridana smalli).

Alligood CA, Wheaton CJ, Forde HM, Smith KN, Daneault AJ, Carlson RC, Savage A.

Zoo Biol. 2008 Sep;27(5):394-405. doi: 10.1002/zoo.20205.


Physiological effects of concentrated barley beta-glucan in mildly hypercholesterolemic adults.

Smith KN, Queenan KM, Thomas W, Fulcher RG, Slavin JL.

J Am Coll Nutr. 2008 Jun;27(3):434-40.


Kinetics and mechanism of nucleophilic addition to nitric oxide: secondary amine diazeniumdiolation.

Bohle DS, Smith KN.

Inorg Chem. 2008 May 19;47(10):3925-7. doi: 10.1021/ic800027m. Epub 2008 Apr 12.


Conservation partnerships between Zoos and Aquariums, federal and state agencies, and nongovernmental organizations.

Smith KN, Shaw JH, Bettinger T, Caniglia B, Carter T.

Zoo Biol. 2007 Nov;26(6):471-86. doi: 10.1002/zoo.20142.


E/Z conformation and the vibrational spectroscopy of Me2NN(O)=NOMe.

Bohle DS, Ivanic J, Saavedra JE, Smith KN, Wang YN.

J Phys Chem A. 2005 Dec 15;109(49):11317-21.


Chemistry of the diazeniumdiolates. O- versus N-alkylation of the RNH[N(O)NO](-) ion.

Saavedra JE, Bohle DS, Smith KN, George C, Deschamps JR, Parrish D, Ivanic J, Wang YN, Citro ML, Keefer LK.

J Am Chem Soc. 2004 Oct 13;126(40):12880-7.


Trolox selectively enhances arsenic-mediated oxidative stress and apoptosis in APL and other malignant cell lines.

Diaz Z, Colombo M, Mann KK, Su H, Smith KN, Bohle DS, Schipper HM, Miller WH Jr.

Blood. 2005 Feb 1;105(3):1237-45. Epub 2004 Oct 5.


Spinal 2-chloroprocaine: a dose-ranging study and the effect of added epinephrine.

Smith KN, Kopacz DJ, McDonald SB.

Anesth Analg. 2004 Jan;98(1):81-8, table of contents.


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