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Linking internal dosimetries of the propyl metabolic series in rats and humans using physiologically based pharmacokinetic (PBPK) modeling.

Smith JN, Tyrrell KJ, Smith JP, Weitz KK, Faber W.

Regul Toxicol Pharmacol. 2019 Oct 24:104507. doi: 10.1016/j.yrtph.2019.104507. [Epub ahead of print]


Physiologically based pharmacokinetic modeling of salivary concentrations for non-invasive biomonitoring of 2,4-dichlorophenoxyacetic acid (2,4-D).

Han AA, Timchalk C, Carver ZA, Weber TJ, Tyrrell KJ, Sontag RL, Gibbins T, Chrisler WB, Weitz KK, Du D, Lin Y, Smith JN.

Toxicol Sci. 2019 Sep 24. pii: kfz206. doi: 10.1093/toxsci/kfz206. [Epub ahead of print]


Predictors of Hearing Aid Use in the Advanced Digital Era: An Investigation of Benefit, Satisfaction, and Self-Efficacy.

Jilla AM, Johnson CE, Danhauer JL, Anderson M, Smith JN, Sullivan JC, Sanchez KR.

J Am Acad Audiol. 2019 Aug 16. doi: 10.3766/jaaa.18036. [Epub ahead of print]


Novel Ionization Reagent for the Measurement of Gas Phase Ammonia and Amines using a Stand-alone Atmospheric Pressure Gas Chromatography (APGC) Source.

Perraud V, Li X, Smith JN, Finlayson-Pitts BJ.

Rapid Commun Mass Spectrom. 2019 Aug 19. doi: 10.1002/rcm.8561. [Epub ahead of print]


Unprecedented peroxidase-mimicking activity of single-atom nanozyme with atomically dispersed Fe-Nx moieties hosted by MOF derived porous carbon.

Niu X, Shi Q, Zhu W, Liu D, Tian H, Fu S, Cheng N, Li S, Smith JN, Du D, Lin Y.

Biosens Bioelectron. 2019 Oct 1;142:111495. doi: 10.1016/j.bios.2019.111495. Epub 2019 Jul 10.


An Experimental and Modeling Study of Nanoparticle Formation and Growth from Dimethylamine and Nitric Acid.

Chee S, Myllys N, Barsanti KC, Wong BM, Smith JN.

J Phys Chem A. 2019 Jul 5;123(26):5640-5648. doi: 10.1021/acs.jpca.9b03326. Epub 2019 Jun 20.


Stable Acinar Progenitor Cell Model Identifies Treacle-Dependent Radioresistance.

Weber TJ, Qian WJ, Smith JN, Gritsenko MA, Hu D, Chrisler WB, Timchalk C.

Radiat Res. 2019 Aug;192(2):135-144. doi: 10.1667/RR15342.1. Epub 2019 May 29.


Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B.

Frisch BJ, Hoffman CM, Latchney SE, LaMere MW, Myers J, Ashton J, Li AJ, Saunders J 2nd, Palis J, Perkins AS, McCabe A, Smith JN, McGrath KE, Rivera-Escalera F, McDavid A, Liesveld JL, Korshunov VA, Elliott MR, MacNamara KC, Becker MW, Calvi LM.

JCI Insight. 2019 Apr 18;5. pii: 124213. doi: 10.1172/jci.insight.124213.


Benzo[ a]pyrene Induction of Glutathione S-Transferases: An Activity-Based Protein Profiling Investigation.

Stoddard EG, Killinger BJ, Nag SA, Martin J, Corley R, Smith JN, Wright AT.

Chem Res Toxicol. 2019 Jun 17;32(6):1259-1267. doi: 10.1021/acs.chemrestox.9b00069. Epub 2019 Apr 12.


Impact of a simulated electronic health record on pharmacy students' perceptions of preparedness for clinical practice.

Smith JN, Scholtz JM.

Curr Pharm Teach Learn. 2018 Dec;10(12):1624-1630. doi: 10.1016/j.cptl.2018.09.008. Epub 2018 Sep 12.


All that is silver is not toxic: silver ion and particle kinetics reveals the role of silver ion aging and dosimetry on the toxicity of silver nanoparticles.

Smith JN, Thomas DG, Jolley H, Kodali VK, Littke MH, Munusamy P, Baer DR, Gaffrey MJ, Thrall BD, Teeguarden JG.

Part Fibre Toxicol. 2018 Dec 5;15(1):47. doi: 10.1186/s12989-018-0283-z.


Impact of lithiated cobalt oxide and phosphate nanoparticles on rainbow trout gill epithelial cells.

Melby ES, Cui Y, Borgatta J, Mensch AC, Hang MN, Chrisler WB, Dohnalkova A, Van Gilder JM, Alvarez CM, Smith JN, Hamers RJ, Orr G.

Nanotoxicology. 2018 Dec;12(10):1166-1181. doi: 10.1080/17435390.2018.1508785. Epub 2018 Nov 19.


Lens-regulated retinoic acid signalling controls expansion of the developing eye.

Smith JN, Walker HM, Thompson H, Collinson JM, Vargesson N, Erskine L.

Development. 2018 Oct 10;145(19). pii: dev167171. doi: 10.1242/dev.167171.


Describing pharmacy student participation in an international, interprofessional medical mission trip as part of an advanced pharmacy practice experience (APPE).

Smith JN, Phan Y, Johnson M, Emmerson K, West BO, Adams J, McGiness T, Otsuka S.

Curr Pharm Teach Learn. 2018 Jul;10(7):940-945. doi: 10.1016/j.cptl.2018.04.009. Epub 2018 Apr 27.


Impact of an interprofessional transition of care service on 30-day hospital reutilizations.

Otsuka S, Smith JN, Pontiggia L, Patel RV, Day SC, Grande DT.

J Interprof Care. 2018 Aug 29:1-6. doi: 10.1080/13561820.2018.1513466. [Epub ahead of print]


Rapid growth of organic aerosol nanoparticles over a wide tropospheric temperature range.

Stolzenburg D, Fischer L, Vogel AL, Heinritzi M, Schervish M, Simon M, Wagner AC, Dada L, Ahonen LR, Amorim A, Baccarini A, Bauer PS, Baumgartner B, Bergen A, Bianchi F, Breitenlechner M, Brilke S, Buenrostro Mazon S, Chen D, Dias A, Draper DC, Duplissy J, El Haddad I, Finkenzeller H, Frege C, Fuchs C, Garmash O, Gordon H, He X, Helm J, Hofbauer V, Hoyle CR, Kim C, Kirkby J, Kontkanen J, Kürten A, Lampilahti J, Lawler M, Lehtipalo K, Leiminger M, Mai H, Mathot S, Mentler B, Molteni U, Nie W, Nieminen T, Nowak JB, Ojdanic A, Onnela A, Passananti M, Petäjä T, Quéléver LLJ, Rissanen MP, Sarnela N, Schallhart S, Tauber C, Tomé A, Wagner R, Wang M, Weitz L, Wimmer D, Xiao M, Yan C, Ye P, Zha Q, Baltensperger U, Curtius J, Dommen J, Flagan RC, Kulmala M, Smith JN, Worsnop DR, Hansel A, Donahue NM, Winkler PM.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9122-9127. doi: 10.1073/pnas.1807604115. Epub 2018 Aug 28.


Evaluation of non-invasive biomonitoring of 2,4-Dichlorophenoxyacetic acid (2,4-D) in saliva.

Carver ZA, Han AA, Timchalk C, Weber TJ, Tyrrell KJ, Sontag RL, Luders T, Chrisler WB, Weitz KK, Smith JN.

Toxicology. 2018 Dec 1;410:171-181. doi: 10.1016/j.tox.2018.08.003. Epub 2018 Aug 16.


Type I IFNs drive hematopoietic stem and progenitor cell collapse via impaired proliferation and increased RIPK1-dependent cell death during shock-like ehrlichial infection.

Smith JNP, Zhang Y, Li JJ, McCabe A, Jo HJ, Maloney J, MacNamara KC.

PLoS Pathog. 2018 Aug 6;14(8):e1007234. doi: 10.1371/journal.ppat.1007234. eCollection 2018 Aug.


Multifunctional Activity-Based Protein Profiling of the Developing Lung.

Stoddard EG, Volk RF, Carson JP, Ljungberg CM, Murphree TA, Smith JN, Sadler NC, Shukla AK, Ansong C, Wright AT.

J Proteome Res. 2018 Aug 3;17(8):2623-2634. doi: 10.1021/acs.jproteome.8b00086. Epub 2018 Jul 18.


Spatially Resolved Proteome Mapping of Laser Capture Microdissected Tissue with Automated Sample Transfer to Nanodroplets.

Zhu Y, Dou M, Piehowski PD, Liang Y, Wang F, Chu RK, Chrisler WB, Smith JN, Schwarz KC, Shen Y, Shukla AK, Moore RJ, Smith RD, Qian WJ, Kelly RT.

Mol Cell Proteomics. 2018 Sep;17(9):1864-1874. doi: 10.1074/mcp.TIR118.000686. Epub 2018 Jun 24.


Directed evolution and biophysical characterization of a full-length, soluble, human caveolin-1 variant.

Smith JN, Edgar JM, Balk JM, Iftikhar M, Fong JC, Olsen TJ, Fishman DA, Majumdar S, Weiss GA.

Biochim Biophys Acta Proteins Proteom. 2018 Sep;1866(9):963-972. doi: 10.1016/j.bbapap.2018.05.014. Epub 2018 May 29.


Hematopoietic stem cell loss and hematopoietic failure in severe aplastic anemia is driven by macrophages and aberrant podoplanin expression.

McCabe A, Smith JNP, Costello A, Maloney J, Katikaneni D, MacNamara KC.

Haematologica. 2018 Sep;103(9):1451-1461. doi: 10.3324/haematol.2018.189449. Epub 2018 May 17.


Echolocation click source parameters of Australian snubfin dolphins (Orcaella heinsohni).

de Freitas M, Smith JN, Jensen FH, Beedholm K, Madsen PT.

J Acoust Soc Am. 2018 Apr;143(4):2564. doi: 10.1121/1.5034174.


Rigid tetraarylene-bridged cavitands from reduced-symmetry resorcin[4]arene derivatives.

Smith JN, Lucas NT.

Chem Commun (Camb). 2018 May 7;54(37):4716-4719. doi: 10.1039/c8cc01903g. Epub 2018 Apr 23.


Dual-Readout Immunochromatographic Assay by Utilizing MnO2 Nanoflowers as the Unique Colorimetric/Chemiluminescent Probe.

Ouyang H, Lu Q, Wang W, Song Y, Tu X, Zhu C, Smith JN, Du D, Fu Z, Lin Y.

Anal Chem. 2018 Apr 17;90(8):5147-5152. doi: 10.1021/acs.analchem.7b05247. Epub 2018 Apr 4.


Practical approaches for overcoming challenges in heightened characterization of antibody-drug conjugates with new methodologies and ultrahigh-resolution mass spectrometry.

Friese OV, Smith JN, Brown PW, Rouse JC.

MAbs. 2018 Apr;10(3):335-345. doi: 10.1080/19420862.2018.1433973. Epub 2018 Feb 20. Review.


Zika virus infection elicits auto-antibodies to C1q.

Koma T, Veljkovic V, Anderson DE, Wang LF, Rossi SL, Shan C, Shi PY, Beasley DW, Bukreyeva N, Smith JN, Hallam S, Huang C, von Messling V, Paessler S.

Sci Rep. 2018 Jan 30;8(1):1882. doi: 10.1038/s41598-018-20185-8.


ISD3: a particokinetic model for predicting the combined effects of particle sedimentation, diffusion and dissolution on cellular dosimetry for in vitro systems.

Thomas DG, Smith JN, Thrall BD, Baer DR, Jolley H, Munusamy P, Kodali V, Demokritou P, Cohen J, Teeguarden JG.

Part Fibre Toxicol. 2018 Jan 25;15(1):6. doi: 10.1186/s12989-018-0243-7.


SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids.

Zhang X, Romm M, Zheng X, Zink EM, Kim YM, Burnum-Johnson KE, Orton DJ, Apffel A, Ibrahim YM, Monroe ME, Moore RJ, Smith JN, Ma J, Renslow RS, Thomas DG, Blackwell AE, Swinford G, Sausen J, Kurulugama RT, Eno N, Darland E, Stafford G, Fjeldsted J, Metz TO, Teeguarden JG, Smith RD, Baker ES.

Clin Mass Spectrom. 2016 Dec;2:1-10. doi: 10.1016/j.clinms.2016.11.002. Epub 2016 Dec 29.


Superphenylphosphines: Nanographene-Based Ligands That Control Coordination Geometry and Drive Supramolecular Assembly.

Smith JN, Hook JM, Lucas NT.

J Am Chem Soc. 2018 Jan 24;140(3):1131-1141. doi: 10.1021/jacs.7b12251. Epub 2018 Jan 9.


Plasma Protein Turnover Rates in Rats Using Stable Isotope Labeling, Global Proteomics, and Activity-Based Protein Profiling.

Smith JN, Tyrrell KJ, Hansen JR, Thomas DG, Murphree TA, Shukla A, Luders T, Madden JM, Li Y, Wright AT, Piehowski PD.

Anal Chem. 2017 Dec 19;89(24):13559-13566. doi: 10.1021/acs.analchem.7b03984. Epub 2017 Dec 6.


Activity-Based Probes for Isoenzyme- and Site-Specific Functional Characterization of Glutathione S-Transferases.

Stoddard EG, Killinger BJ, Nair RN, Sadler NC, Volk RF, Purvine SO, Shukla AK, Smith JN, Wright AT.

J Am Chem Soc. 2017 Nov 15;139(45):16032-16035. doi: 10.1021/jacs.7b07378. Epub 2017 Nov 1.


Recent Transport History of Fukushima Radioactivity in the Northeast Pacific Ocean.

Smith JN, Rossi V, Buesseler KO, Cullen JT, Cornett J, Nelson R, Macdonald AM, Robert M, Kellogg J.

Environ Sci Technol. 2017 Sep 19;51(18):10494-10502. doi: 10.1021/acs.est.7b02712. Epub 2017 Sep 6.


A 3D-Printed, Portable, Optical-Sensing Platform for Smartphones Capable of Detecting the Herbicide 2,4-Dichlorophenoxyacetic Acid.

Wang Y, Zeinhom MMA, Yang M, Sun R, Wang S, Smith JN, Timchalk C, Li L, Lin Y, Du D.

Anal Chem. 2017 Sep 5;89(17):9339-9346. doi: 10.1021/acs.analchem.7b02139. Epub 2017 Aug 21.


Preliminary estimates of the abundance and fidelity of dolphins associating with a demersal trawl fishery.

Allen SJ, Pollock KH, Bouchet PJ, Kobryn HT, McElligott DB, Nicholson KE, Smith JN, Loneragan NR.

Sci Rep. 2017 Jul 10;7(1):4995. doi: 10.1038/s41598-017-05189-0.


Central Arterial Function Measured by Non-invasive Pulse Wave Analysis is Abnormal in Patients with Duchenne Muscular Dystrophy.

Ryan TD, Parent JJ, Gao Z, Khoury PR, Dupont E, Smith JN, Wong B, Urbina EM, Jefferies JL.

Pediatr Cardiol. 2017 Aug;38(6):1269-1276. doi: 10.1007/s00246-017-1657-y. Epub 2017 Jun 21.


Protein Folding Using a Vortex Fluidic Device.

Britton J, Smith JN, Raston CL, Weiss GA.

Methods Mol Biol. 2017;1586:211-220. doi: 10.1007/978-1-4939-6887-9_13.


Accountable Care in Transitions (ACTion): A Team-Based Approach to Reducing Hospital Utilization in a Patient-Centered Medical Home.

Hawes EM, Smith JN, Pinelli NR, Adams R, Tong G, Weir S, Gwynne M.

J Pharm Pract. 2018 Apr;31(2):175-182. doi: 10.1177/0897190017707118. Epub 2017 May 3.


Pontellid copepods, Labidocera spp., affected by ocean acidification: A field study at natural CO2 seeps.

Smith JN, Richter C, Fabricius KE, Cornils A.

PLoS One. 2017 May 3;12(5):e0175663. doi: 10.1371/journal.pone.0175663. eCollection 2017.


Predicting Transport of 3,5,6-Trichloro-2-Pyridinol Into Saliva Using a Combination Experimental and Computational Approach.

Smith JN, Carver ZA, Weber TJ, Timchalk C.

Toxicol Sci. 2017 Jun 1;157(2):438-450. doi: 10.1093/toxsci/kfx055.


Use of a probabilistic PBPK/PD model to calculate Data Derived Extrapolation Factors for chlorpyrifos.

Poet TS, Timchalk C, Bartels MJ, Smith JN, McDougal R, Juberg DR, Price PS.

Regul Toxicol Pharmacol. 2017 Jun;86:59-73. doi: 10.1016/j.yrtph.2017.02.014. Epub 2017 Feb 24.


DSCAM promotes axon fasciculation and growth in the developing optic pathway.

Bruce FM, Brown S, Smith JN, Fuerst PG, Erskine L.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1702-1707. doi: 10.1073/pnas.1618606114. Epub 2017 Jan 30.


In vitro metabolism of benzo[a]pyrene-7,8-dihydrodiol and dibenzo[def,p]chrysene-11,12 diol in rodent and human hepatic microsomes.

Smith JN, Mehinagic D, Nag S, Crowell SR, Corley RA.

Toxicol Lett. 2017 Mar 5;269:23-32. doi: 10.1016/j.toxlet.2017.01.008. Epub 2017 Jan 21.


Anticancer properties of baicalein: a review.

Gao Y, Snyder SA, Smith JN, Chen YC.

Med Chem Res. 2016 Aug;25(8):1515-1523. doi: 10.1007/s00044-016-1607-x. Epub 2016 Jun 29.


Could the Transition movement help solve the NHS's problems?

Smith JN, Hopkins R, Pencheon D.

J Public Health (Oxf). 2017 Dec 1;39(4):841-845. doi: 10.1093/pubmed/fdw129.


Amazon boundary layer aerosol concentration sustained by vertical transport during rainfall.

Wang J, Krejci R, Giangrande S, Kuang C, Barbosa HM, Brito J, Carbone S, Chi X, Comstock J, Ditas F, Lavric J, Manninen HE, Mei F, Moran-Zuloaga D, Pöhlker C, Pöhlker ML, Saturno J, Schmid B, Souza RA, Springston SR, Tomlinson JM, Toto T, Walter D, Wimmer D, Smith JN, Kulmala M, Machado LA, Artaxo P, Andreae MO, Petäjä T, Martin ST.

Nature. 2016 Nov 17;539(7629):416-419. doi: 10.1038/nature19819. Epub 2016 Oct 24.


Global atmospheric particle formation from CERN CLOUD measurements.

Dunne EM, Gordon H, Kürten A, Almeida J, Duplissy J, Williamson C, Ortega IK, Pringle KJ, Adamov A, Baltensperger U, Barmet P, Benduhn F, Bianchi F, Breitenlechner M, Clarke A, Curtius J, Dommen J, Donahue NM, Ehrhart S, Flagan RC, Franchin A, Guida R, Hakala J, Hansel A, Heinritzi M, Jokinen T, Kangasluoma J, Kirkby J, Kulmala M, Kupc A, Lawler MJ, Lehtipalo K, Makhmutov V, Mann G, Mathot S, Merikanto J, Miettinen P, Nenes A, Onnela A, Rap A, Reddington CL, Riccobono F, Richards NA, Rissanen MP, Rondo L, Sarnela N, Schobesberger S, Sengupta K, Simon M, Sipilä M, Smith JN, Stozkhov Y, Tomé A, Tröstl J, Wagner PE, Wimmer D, Winkler PM, Worsnop DR, Carslaw KS.

Science. 2016 Dec 2;354(6316):1119-1124. Epub 2016 Oct 27.


Hematopoietic Stem Cell Regulation by Type I and II Interferons in the Pathogenesis of Acquired Aplastic Anemia.

Smith JN, Kanwar VS, MacNamara KC.

Front Immunol. 2016 Aug 29;7:330. doi: 10.3389/fimmu.2016.00330. eCollection 2016. Review.


Effect of dimethylamine on the gas phase sulfuric acid concentration measured by Chemical Ionization Mass Spectrometry.

Rondo L, Ehrhart S, Kürten A, Adamov A, Bianchi F, Breitenlechner M, Duplissy J, Franchin A, Dommen J, Donahue NM, Dunne EM, Flagan RC, Hakala J, Hansel A, Keskinen H, Kim J, Jokinen T, Lehtipalo K, Leiminger M, Praplan A, Riccobono F, Rissanen MP, Sarnela N, Schobesberger S, Simon M, Sipilä M, Smith JN, Tomé A, Tröstl J, Tsagkogeorgas G, Vaattovaara P, Winkler PM, Williamson C, Wimmer D, Baltensperger U, Kirkby J, Kulmala M, Petäjä T, Worsnop DR, Curtius J.

J Geophys Res Atmos. 2016 Mar 27;121(6):3036-3049. Epub 2016 Mar 24.


The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor.

Koma T, Huang C, Aronson JF, Walker AG, Miller M, Smith JN, Patterson M, Paessler S.

PLoS Negl Trop Dis. 2016 Aug 31;10(8):e0004969. doi: 10.1371/journal.pntd.0004969. eCollection 2016 Aug.

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