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The positive allosteric modulator of α2/3-containing GABAA receptors, KRM-II-81, is active in pharmaco-resistant models of epilepsy and reduces hyperexcitability after traumatic brain injury.

Witkin JM, Li G, Golani LK, Xiong W, Smith JL, Ping X, Rashid F, Jahan R, Cerne R, Cook JM, Jin X.

J Pharmacol Exp Ther. 2019 Nov 6. pii: jpet.119.260968. doi: 10.1124/jpet.119.260968. [Epub ahead of print]


Stereodivergent, Chemoenzymatic Synthesis of Azaphilone Natural Products.

Pyser JB, Baker Dockrey SA, Benítez AR, Joyce LA, Wiscons RA, Smith JL, Narayan ARH.

J Am Chem Soc. 2019 Nov 6. doi: 10.1021/jacs.9b09385. [Epub ahead of print]


Anatomy of the palmar cutaneous branch of the median nerve: A review.

Smith JL, Ebraheim NA.

J Orthop. 2019 Jun 5;16(6):576-579. doi: 10.1016/j.jor.2019.06.010. eCollection 2019 Nov-Dec. Review.


Factors Associated With Length of Stay in Emergency Departments for Pediatric Patients With Psychiatric Problems.

Smith JL, De Nadai AS, Petrila J, Storch EA.

Pediatr Emerg Care. 2019 Oct;35(10):716-721. doi: 10.1097/PEC.0000000000001651.


Combined ipilimumab and nivolumab first-line and after BRAF-targeted therapy in advanced melanoma.

Mason R, Dearden HC, Nguyen B, Oon JS, Smith JL, Randhawa M, Mant A, Warburton L, Lo S, Meniawy T, Guminski A, Parente P, Ali S, Haydon A, Long GV, Carlino MS, Millward M, Atkinson VG, Menzies AM.

Pigment Cell Melanoma Res. 2019 Oct 6. doi: 10.1111/pcmr.12831. [Epub ahead of print]


Flexibility in nucleic acid binding is central to APOBEC3H antiviral activity.

Bohn JA, DaSilva J, Kharytonchyk S, Mercedes M, Vosters J, Telesnitsky A, Hatziioannou T, Smith JL.

J Virol. 2019 Oct 2. pii: JVI.01275-19. doi: 10.1128/JVI.01275-19. [Epub ahead of print]


Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.

Dan Q, Newmister SA, Klas KR, Fraley AE, McAfoos TJ, Somoza AD, Sunderhaus JD, Ye Y, Shende VV, Yu F, Sanders JN, Brown WC, Zhao L, Paton RS, Houk KN, Smith JL, Sherman DH, Williams RM.

Nat Chem. 2019 Nov;11(11):972-980. doi: 10.1038/s41557-019-0326-6. Epub 2019 Sep 23.


A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport.

Shlevkov E, Basu H, Bray MA, Sun Z, Wei W, Apaydin K, Karhohs K, Chen PF, Smith JLM, Wiskow O, Roet K, Huang X, Eggan K, Carpenter AE, Kleiman RJ, Schwarz TL.

Cell Rep. 2019 Sep 17;28(12):3224-3237.e5. doi: 10.1016/j.celrep.2019.08.035.


Binge Drinking among Economically Disadvantaged African American Older Adults with Diabetes.

Assari S, Smith JL, Saqib M, Bazargan M.

Behav Sci (Basel). 2019 Sep 11;9(9). pii: E97. doi: 10.3390/bs9090097.


Getting a clinical innovation into practice: An introduction to implementation strategies.

Kirchner JE, Smith JL, Powell BJ, Waltz TJ, Proctor EK.

Psychiatry Res. 2019 Jul 2:112467. doi: 10.1016/j.psychres.2019.06.042. [Epub ahead of print]


Impact of Savoring Ability on the Relationship Between Older Adults' Activity Engagement and Well-Being.

Smith JL, Bihary JG, O'Connor D, Basic A, O'Brien CJ.

J Appl Gerontol. 2019 Sep 3:733464819871876. doi: 10.1177/0733464819871876. [Epub ahead of print]


Radiological and clinical predictors of scoliosis in patients with Chiari malformation type I and spinal cord syrinx from the Park-Reeves Syringomyelia Research Consortium.

Strahle JM, Taiwo R, Averill C, Torner J, Shannon CN, Bonfield CM, Tuite GF, Bethel-Anderson T, Rutlin J, Brockmeyer DL, Wellons JC, Leonard JR, Mangano FT, Johnston JM, Shah MN, Iskandar BJ, Tyler-Kabara EC, Daniels DJ, Jackson EM, Grant GA, Couture DE, Adelson PD, Alden TD, Aldana PR, Anderson RCE, Selden NR, Baird LC, Bierbrauer K, Chern JJ, Whitehead WE, Ellenbogen RG, Fuchs HE, Guillaume DJ, Hankinson TC, Iantosca MR, Oakes WJ, Keating RF, Khan NR, Muhlbauer MS, McComb JG, Menezes AH, Ragheb J, Smith JL, Maher CO, Greene S, Kelly M, O'Neill BR, Krieger MD, Tamber M, Durham SR, Olavarria G, Stone SSD, Kaufman BA, Heuer GG, Bauer DF, Albert G, Greenfield JP, Wait SD, Van Poppel MD, Eskandari R, Mapstone T, Shimony JS, Dacey RG, Smyth MD, Park TS, Limbrick DD.

J Neurosurg Pediatr. 2019 Aug 16:1-8. doi: 10.3171/2019.5.PEDS18527. [Epub ahead of print]


Rapid-acting antidepressants.

Witkin JM, Martin AE, Golani LK, Xu NZ, Smith JL.

Adv Pharmacol. 2019;86:47-96. doi: 10.1016/bs.apha.2019.03.002. Epub 2019 Apr 24.


The value of human epileptic tissue in the characterization and development of novel antiepileptic drugs: The example of CERC-611 and KRM-II-81.

Witkin JM, Ping X, Cerne R, Mouser C, Jin X, Hobbs J, Tiruveedhula VVNPB, Li G, Jahan R, Rashid F, Kumar Golani L, Cook JM, Smith JL.

Brain Res. 2019 Nov 1;1722:146356. doi: 10.1016/j.brainres.2019.146356. Epub 2019 Jul 29. Review.


Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.

Benítez AR, Tweedy S, Baker Dockrey SA, Lukowski AL, Wymore T, Khare D, Brooks CL 3rd, Palfey BA, Smith JL, Narayan ARH.

ACS Catal. 2019 Apr 5;9(4):3633-3640. doi: 10.1021/acscatal.8b04575. Epub 2019 Mar 25.


Development and validation of a deep learning algorithm for improving Gleason scoring of prostate cancer.

Nagpal K, Foote D, Liu Y, Chen PC, Wulczyn E, Tan F, Olson N, Smith JL, Mohtashamian A, Wren JH, Corrado GS, MacDonald R, Peng LH, Amin MB, Evans AJ, Sangoi AR, Mermel CH, Hipp JD, Stumpe MC.

NPJ Digit Med. 2019 Jun 7;2:48. doi: 10.1038/s41746-019-0112-2. eCollection 2019.


A medium throughput rodent model of relapse from addiction with behavioral and pharmacological specificity.

Eiler WJA 2nd, Gleason SD, Smith JL, Witkin JM.

Pharmacol Biochem Behav. 2019 Aug;183:72-79. doi: 10.1016/j.pbb.2019.06.005. Epub 2019 Jun 14.


Structural Determinants of the APOBEC3G N-Terminal Domain for HIV-1 RNA Association.

Fukuda H, Li S, Sardo L, Smith JL, Yamashita K, Sarca AD, Shirakawa K, Standley DM, Takaori-Kondo A, Izumi T.

Front Cell Infect Microbiol. 2019 May 21;9:129. doi: 10.3389/fcimb.2019.00129. eCollection 2019.


Utility of calcium, magnesium and phosphate testing in the emergency department.

Date PA, Smith JL, Spencer WS, de Tonnerre EJ, Yeoh MJ, Taylor DM.

Emerg Med Australas. 2019 Jun 2. doi: 10.1111/1742-6723.13332. [Epub ahead of print]


Assessing malaria risk at night-time venues in a low-transmission setting: a time-location sampling study in Zambezi, Namibia.

Jacobson JO, Smith JL, Cueto C, Chisenga M, Roberts K, Hsiang M, Gosling R, Mumbengegwi D, Bennett A.

Malar J. 2019 May 22;18(1):179. doi: 10.1186/s12936-019-2807-x.


Susceptibility of Different Instars of Striacosta albicosta (Lepidoptera: Noctuidae) to Vip3A, a Bacillus thuringiensis (Bacillaceae: Bacillales) Protein.

Farhan Y, Smith JL, Schaafsma AW.

J Econ Entomol. 2019 Sep 23;112(5):2335-2344. doi: 10.1093/jee/toz118.


FLASH: a next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences.

Quan J, Langelier C, Kuchta A, Batson J, Teyssier N, Lyden A, Caldera S, McGeever A, Dimitrov B, King R, Wilheim J, Murphy M, Ares LP, Travisano KA, Sit R, Amato R, Mumbengegwi DR, Smith JL, Bennett A, Gosling R, Mourani PM, Calfee CS, Neff NF, Chow ED, Kim PS, Greenhouse B, DeRisi JL, Crawford ED.

Nucleic Acids Res. 2019 Aug 22;47(14):e83. doi: 10.1093/nar/gkz418.


Chronic Respiratory Disease and Health-Related Quality of Life of African American Older Adults in an Economically Disadvantaged Area of Los Angeles.

Bazargan M, Smith JL, Robinson P, Uyanne J, Abdulrahoof R, Chuku C, Assari S.

Int J Environ Res Public Health. 2019 May 17;16(10). pii: E1756. doi: 10.3390/ijerph16101756.


Copy number variant and runs of homozygosity detection by microarrays enabled more precise molecular diagnoses in 11,020 clinical exome cases.

Dharmadhikari AV, Ghosh R, Yuan B, Liu P, Dai H, Al Masri S, Scull J, Posey JE, Jiang AH, He W, Vetrini F, Braxton AA, Ward P, Chiang T, Qu C, Gu S, Shaw CA, Smith JL, Lalani S, Stankiewicz P, Cheung SW, Bacino CA, Patel A, Breman AM, Wang X, Meng L, Xiao R, Xia F, Muzny D, Gibbs RA, Beaudet AL, Eng CM, Lupski JR, Yang Y, Bi W.

Genome Med. 2019 May 17;11(1):30. doi: 10.1186/s13073-019-0639-5.


Designing malaria surveillance strategies for mobile and migrant populations in Nepal: a mixed-methods study.

Smith JL, Ghimire P, Rijal KR, Maglior A, Hollis S, Andrade-Pacheco R, Das Thakur G, Adhikari N, Thapa Shrestha U, Banjara MR, Lal BK, Jacobson JO, Bennett A.

Malar J. 2019 May 3;18(1):158. doi: 10.1186/s12936-019-2791-1.


A Fluorescence-Activated Single-Droplet Dispenser for High Accuracy Single-Droplet and Single-Cell Sorting and Dispensing.

Qin Y, Wu L, Wang J, Han R, Shen J, Wang J, Xu S, Paguirigan AL, Smith JL, Radich JP, Chiu DT.

Anal Chem. 2019 May 21;91(10):6815-6819. doi: 10.1021/acs.analchem.9b01017. Epub 2019 May 9.


Current barriers, facilitators and future improvements to advance quality of abortion care: views of women.

Smith JL, Cameron S.

BMJ Sex Reprod Health. 2019 Apr 26. pii: bmjsrh-2018-200264. doi: 10.1136/bmjsrh-2018-200264. [Epub ahead of print]


An Emergency Medicine Remediation Consult Service: Access to Expert Remediation Advice and Resources.

Egan DJ, Gentges J, Regan L, Smith JL, Williamson K, Murano T.

AEM Educ Train. 2019 Mar 14;3(2):193-196. doi: 10.1002/aet2.10330. eCollection 2019 Apr.


Perceived risk of colorectal and breast cancers among women who are overweight or with obesity.

Hall IJ, Soman A, Smith JL, White A, Crawford A.

Prev Med Rep. 2019 Mar 22;14:100845. doi: 10.1016/j.pmedr.2019.100845. eCollection 2019 Jun.


CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling.

Mou H, Ozata DM, Smith JL, Sheel A, Kwan SY, Hough S, Kucukural A, Kennedy Z, Cao Y, Xue W.

Genome Med. 2019 Apr 16;11(1):21. doi: 10.1186/s13073-019-0627-9.


Cigarette Smoking among Economically Disadvantaged African-American Older Adults in South Los Angeles: Gender Differences.

Assari S, Smith JL, Zimmerman MA, Bazargan M.

Int J Environ Res Public Health. 2019 Apr 4;16(7). pii: E1208. doi: 10.3390/ijerph16071208.


Emergency Department Utilization among Underserved African American Older Adults in South Los Angeles.

Bazargan M, Smith JL, Cobb S, Barkley L, Wisseh C, Ngula E, Thomas RJ, Assari S.

Int J Environ Res Public Health. 2019 Apr 2;16(7). pii: E1175. doi: 10.3390/ijerph16071175.


Neonicotinoid insecticide residues in subsurface drainage and open ditch water around maize fields in southwestern Ontario.

Schaafsma AW, Limay-Rios V, Baute TS, Smith JL.

PLoS One. 2019 Apr 4;14(4):e0214787. doi: 10.1371/journal.pone.0214787. eCollection 2019.


Using parasite genetic and human mobility data to infer local and cross-border malaria connectivity in Southern Africa.

Tessema S, Wesolowski A, Chen A, Murphy M, Wilheim J, Mupiri AR, Ruktanonchai NW, Alegana VA, Tatem AJ, Tambo M, Didier B, Cohen JM, Bennett A, Sturrock HJ, Gosling R, Hsiang MS, Smith DL, Mumbengegwi DR, Smith JL, Greenhouse B.

Elife. 2019 Apr 2;8. pii: e43510. doi: 10.7554/eLife.43510.


Comprehensive Summary of Anastomoses between the Median and Ulnar Nerves in the Forearm and Hand.

Smith JL, Siddiqui SA, Ebraheim NA.

J Hand Microsurg. 2019 Apr;11(1):1-5. doi: 10.1055/s-0038-1672335. Epub 2018 Oct 29. Review.


Impact of prey occupancy and other ecological and anthropogenic factors on tiger distribution in Thailand's western forest complex.

Duangchantrasiri S, Jornburom P, Jinamoy S, Pattanavibool A, Hines JE, Arnold TW, Fieberg J, Smith JLD.

Ecol Evol. 2019 Feb 18;9(5):2449-2458. doi: 10.1002/ece3.4845. eCollection 2019 Mar. Erratum in: Ecol Evol. 2019 May 29;9(10):6165.


Structural and dynamical rationale for fatty acid unsaturation in Escherichia coli.

Dodge GJ, Patel A, Jaremko KL, McCammon JA, Smith JL, Burkart MD.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6775-6783. doi: 10.1073/pnas.1818686116. Epub 2019 Mar 14.


Dietary Sodium Intake is Predicted by Antihypertensive Medication Regimen in Patients With Heart Failure.

Smith JL, Lennie TA, Chung ML, Mudd-Martin G.

J Cardiovasc Nurs. 2019 Jul/Aug;34(4):313-318. doi: 10.1097/JCN.0000000000000570.


The α2,3-selective potentiator of GABAA receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats.

Witkin JM, Cerne R, Davis PG, Freeman KB, do Carmo JM, Rowlett JK, Methuku KR, Okun A, Gleason SD, Li X, Krambis MJ, Poe M, Li G, Schkeryantz JM, Jahan R, Yang L, Guo W, Golani LK, Anderson WH, Catlow JT, Jones TM, Porreca F, Smith JL, Knopp KL, Cook JM.

Pharmacol Biochem Behav. 2019 May;180:22-31. doi: 10.1016/j.pbb.2019.02.013. Epub 2019 Feb 27.


Can Inhibitory Training Produce Reductions in Drinking? Evaluating the Influence of the Control Condition.

Liu Q, Hu L, Smith JL, Mewton LR.

J Stud Alcohol Drugs. 2019 Jan;80(1):96-101.


Deferiprone has anti-inflammatory properties and reduces fibroblast migration in vitro.

Ramezanpour M, Smith JLP, Ooi ML, Gouzos M, Psaltis AJ, Wormald PJ, Vreugde S.

Sci Rep. 2019 Feb 20;9(1):2378. doi: 10.1038/s41598-019-38902-2.


Incidence, features and management of radionecrosis in melanoma patients treated with cerebral radiotherapy and anti-PD-1 antibodies.

Pires da Silva I, Glitza IC, Haydu LE, Johnpulle R, Banks PD, Grass GD, Goldinger SMA, Smith JL, Everett AS, Koelblinger P, Roberts-Thomson R, Millward M, Atkinson VG, Guminski A, Kapoor R, Conry RM, Carlino MS, Wang W, Shackleton MJ, Eroglu Z, Lo S, Hong AM, Long GV, Johnson DB, Menzies AM.

Pigment Cell Melanoma Res. 2019 Jul;32(4):553-563. doi: 10.1111/pcmr.12775. Epub 2019 Mar 3.


Prey Lysate Enhances Growth and Toxin Production in an Isolate of Dinophysis acuminata.

Gao H, Tong M, An X, Smith JL.

Toxins (Basel). 2019 Jan 21;11(1). pii: E57. doi: 10.3390/toxins11010057.


Remediation Strategies for Emergency Medicine Patient Care Milestones.

Murano T, Smith JL, Weizberg M.

Cureus. 2018 Nov 7;10(11):e3557. doi: 10.7759/cureus.3557.


Leptospirosis: An important infectious disease in North American horses.

Divers TJ, Chang YF, Irby NL, Smith JL, Carter CN.

Equine Vet J. 2019 May;51(3):287-292. doi: 10.1111/evj.13069. Epub 2019 Jan 28. Review.


Fluctuating Team Science: Perceiving Science as Collaborative Improves Science Motivation.

Allen J, Smith JL, Thoman DB, Walters RW.

Motiv Sci. 2018 Dec;4(4):347-361. doi: 10.1037/mot0000099. Epub 2018 Mar 12. No abstract available.


Structural Basis of Polyketide Synthase O-Methylation.

Skiba MA, Bivins MM, Schultz JR, Bernard SM, Fiers WD, Dan Q, Kulkarni S, Wipf P, Gerwick WH, Sherman DH, Aldrich CC, Smith JL.

ACS Chem Biol. 2018 Dec 21;13(12):3221-3228. doi: 10.1021/acschembio.8b00687. Epub 2018 Dec 3.


Genome-Wide Evolutionary Analysis of Natural History and Adaptation in the World's Tigers.

Liu YC, Sun X, Driscoll C, Miquelle DG, Xu X, Martelli P, Uphyrkina O, Smith JLD, O'Brien SJ, Luo SJ.

Curr Biol. 2018 Dec 3;28(23):3840-3849.e6. doi: 10.1016/j.cub.2018.09.019. Epub 2018 Oct 25.


Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta.

Moss NA, Leão T, Rankin MR, McCullough TM, Qu P, Korobeynikov A, Smith JL, Gerwick L, Gerwick WH.

ACS Chem Biol. 2018 Dec 21;13(12):3385-3395. doi: 10.1021/acschembio.8b00910. Epub 2018 Dec 3.


Understanding and repurposing CRISPR-mediated alternative splicing.

Smith JL, Mou H, Xue W.

Genome Biol. 2018 Nov 6;19(1):184. doi: 10.1186/s13059-018-1565-3.

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