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Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy.

Bertero A, Fields PA, Smith AST, Leonard A, Beussman K, Sniadecki NJ, Kim DH, Tse HF, Pabon L, Shendure J, Noble WS, Murry CE.

J Cell Biol. 2019 Aug 8. pii: jcb.201902117. doi: 10.1083/jcb.201902117. [Epub ahead of print]


Statistical Mechanics of an Elastically Pinned Membrane: Equilibrium Dynamics and Power Spectrum.

Janeš JA, Schmidt D, Blackwell R, Seifert U, Smith AS.

Biophys J. 2019 Aug 6;117(3):542-552. doi: 10.1016/j.bpj.2019.06.036. Epub 2019 Jul 9.


Oxytocin delivered nasally or intraperitoneally reaches the brain and plasma of normal and oxytocin knockout mice.

Smith AS, Korgan AC, Young WS.

Pharmacol Res. 2019 Aug;146:104324. doi: 10.1016/j.phrs.2019.104324. Epub 2019 Jun 22.


Insights from molecular dynamics simulations on structural organization and diffusive dynamics of an ionic liquid at solid and vacuum interfaces.

Vučemilović-Alagić N, Banhatti RD, Stepić R, Wick CR, Berger D, Gaimann MU, Baer A, Harting J, Smith DM, Smith AS.

J Colloid Interface Sci. 2019 Jun 6;553:350-363. doi: 10.1016/j.jcis.2019.06.017. [Epub ahead of print]


MYH9-related disease mutations cause abnormal red blood cell morphology through increased myosin-actin binding at the membrane.

Smith AS, Pal K, Nowak RB, Demenko A, Zaninetti C, Da Costa L, Favier R, Pecci A, Fowler VM.

Am J Hematol. 2019 Jun;94(6):667-677. doi: 10.1002/ajh.25472. Epub 2019 Apr 17.


The Influence of Chemical Change on Protein Dynamics: A Case Study with Pyruvate Formate-Lyase.

Hanževački M, Čondić-Jurkić K, Banhatti RD, Smith AS, Smith DM.

Chemistry. 2019 Jul 2;25(37):8741-8753. doi: 10.1002/chem.201900663. Epub 2019 May 9.


Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines.

Dwyer CJ, Knochelmann HM, Smith AS, Wyatt MM, Rangel Rivera GO, Arhontoulis DC, Bartee E, Li Z, Rubinstein MP, Paulos CM.

Front Immunol. 2019 Feb 20;10:263. doi: 10.3389/fimmu.2019.00263. eCollection 2019. Review.


Universal hidden order in amorphous cellular geometries.

Klatt MA, Lovrić J, Chen D, Kapfer SC, Schaller FM, Schönhöfer PWA, Gardiner BS, Smith AS, Schröder-Turk GE, Torquato S.

Nat Commun. 2019 Feb 18;10(1):811. doi: 10.1038/s41467-019-08360-5.


Evaluation of Holistic Treatment for ALS Reveals Possible Mechanism and Therapeutic Potential.

Lavado A, Guo X, Smith AS, Akanda N, Martin C, Cai Y, Elbrecht D, Tran M, Bryant JP, Colon A, Long CJ, Lambert S, Morgan D, Hickman JJ.

Int J Pharm Pharm Res. 2017 Dec;11(1):348-374. Epub 2017 Dec 30.


Statistical Mechanics of an Elastically Pinned Membrane: Static Profile and Correlations.

Janeš JA, Stumpf H, Schmidt D, Seifert U, Smith AS.

Biophys J. 2019 Jan 22;116(2):283-295. doi: 10.1016/j.bpj.2018.12.003. Epub 2018 Dec 8.


Mechanism of the Water-Gas Shift Reaction Catalyzed by Efficient Ruthenium-Based Catalysts: A Computational and Experimental Study.

Stepić R, Wick CR, Strobel V, Berger D, Vučemilović-Alagić N, Haumann M, Wasserscheid P, Smith AS, Smith DM.

Angew Chem Int Ed Engl. 2019 Jan 14;58(3):741-745. doi: 10.1002/anie.201811627. Epub 2018 Dec 12.


Advances and Current Challenges Associated with the Use of Human Induced Pluripotent Stem Cells in Modeling Neurodegenerative Disease.

Berry BJ, Smith AST, Young JE, Mack DL.

Cells Tissues Organs. 2018;205(5-6):331-349. doi: 10.1159/000493018. Epub 2018 Oct 9. Review.


CAR T Cells in Solid Tumors: Blueprints for Building Effective Therapies.

Knochelmann HM, Smith AS, Dwyer CJ, Wyatt MM, Mehrotra S, Paulos CM.

Front Immunol. 2018 Jul 27;9:1740. doi: 10.3389/fimmu.2018.01740. eCollection 2018. Review.


Physiological Aβ Concentrations Produce a More Biomimetic Representation of the Alzheimer's Disease Phenotype in iPSC Derived Human Neurons.

Berry BJ, Smith AST, Long CJ, Martin CC, Hickman JJ.

ACS Chem Neurosci. 2018 Jul 18;9(7):1693-1701. doi: 10.1021/acschemneuro.8b00067. Epub 2018 May 22.


Clinical prediction rules for abusive head trauma: a systematic review.

Pfeiffer H, Crowe L, Kemp AM, Cowley LE, Smith AS, Babl FE; Paediatric Research in Emergency Departments International Collaborative (PREDICT).

Arch Dis Child. 2018 Aug;103(8):776-783. doi: 10.1136/archdischild-2017-313748. Epub 2018 Apr 5.


Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability.

Smith AS, Nowak RB, Zhou S, Giannetto M, Gokhin DS, Papoin J, Ghiran IC, Blanc L, Wan J, Fowler VM.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4377-E4385. doi: 10.1073/pnas.1718285115. Epub 2018 Apr 2. Erratum in: Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6385.


Regulation of skeletal myotube formation and alignment by nanotopographically controlled cell-secreted extracellular matrix.

Jiao A, Moerk CT, Penland N, Perla M, Kim J, Smith AST, Murry CE, Kim DH.

J Biomed Mater Res A. 2018 Jun;106(6):1543-1551. doi: 10.1002/jbm.a.36351. Epub 2018 Feb 19.


Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence.

Bailey SR, Nelson MH, Majchrzak K, Bowers JS, Wyatt MM, Smith AS, Neal LR, Shirai K, Carpenito C, June CH, Zilliox MJ, Paulos CM.

Nat Commun. 2017 Dec 6;8(1):1961. doi: 10.1038/s41467-017-01867-9.


High-Resolution Fluorescence Microscope Imaging of Erythroblast Structure.

Smith AS, Nowak RB, Fowler VM.

Methods Mol Biol. 2018;1698:205-228. doi: 10.1007/978-1-4939-7428-3_12.


Vasopressinergic Neurocircuitry Regulating Social Attachment in a Monogamous Species.

Tickerhoof MC, Smith AS.

Front Endocrinol (Lausanne). 2017 Oct 11;8:265. doi: 10.3389/fendo.2017.00265. eCollection 2017. Review.


PI3Kδ Inhibition Enhances the Antitumor Fitness of Adoptively Transferred CD8+ T Cells.

Bowers JS, Majchrzak K, Nelson MH, Aksoy BA, Wyatt MM, Smith AS, Bailey SR, Neal LR, Hammerbacher JE, Paulos CM.

Front Immunol. 2017 Sep 29;8:1221. doi: 10.3389/fimmu.2017.01221. eCollection 2017.


Structural basis for the shielding function of the dynamic trypanosome variant surface glycoprotein coat.

Bartossek T, Jones NG, Schäfer C, Cvitković M, Glogger M, Mott HR, Kuper J, Brennich M, Carrington M, Smith AS, Fenz S, Kisker C, Engstler M.

Nat Microbiol. 2017 Nov;2(11):1523-1532. doi: 10.1038/s41564-017-0013-6. Epub 2017 Sep 11.


Effects of pair bonding on parental behavior and dopamine activity in the nucleus accumbens in male prairie voles.

Lei K, Liu Y, Smith AS, Lonstein JS, Wang Z.

Eur J Neurosci. 2017 Oct;46(7):2276-2284. doi: 10.1111/ejn.13673. Epub 2017 Sep 18.


Improving Care With a Portfolio of Physician-Led Cancer Quality Measures at an Academic Center.

Porter JB, Rosenthal EL, Winget M, Smith AS, Seshadri SB, Vetteth Y, Kiamanesh EF, Badwe A, Advani RH, Buyyounouski MK, Coutre S, Dirbas F, Divi V, Dorigo O, Ganjoo KN, Johnston LJ, Recht LD, Shrager JB, Skinner EC, Swetter SM, Visser BC, Blayney DW.

J Oncol Pract. 2017 Aug;13(8):e673-e682. doi: 10.1200/JOP.2017.021139. Epub 2017 Jul 20.


Micro- and nano-patterned conductive graphene-PEG hybrid scaffolds for cardiac tissue engineering.

Smith AST, Yoo H, Yi H, Ahn EH, Lee JH, Shao G, Nagornyak E, Laflamme MA, Murry CE, Kim DH.

Chem Commun (Camb). 2017 Jun 29;53(53):7412-7415. doi: 10.1039/c7cc01988b.


Measuring the Invisible: Determining the Size of Growing Nanodomains Using the "Inverse FCS".

Fenz SF, Smith AS, Monzel C.

Biophys J. 2017 Jun 6;112(11):2245-2246. doi: 10.1016/j.bpj.2017.04.014. No abstract available.


Effect of body deformability on microswimming.

Pande J, Merchant L, Krüger T, Harting J, Smith AS.

Soft Matter. 2017 May 31;13(21):3984-3993. doi: 10.1039/c7sm00181a.


Spatially explicit methodology for coordinated manure management in shared watersheds.

Sharara M, Sampat A, Good LW, Smith AS, Porter P, Zavala VM, Larson R, Runge T.

J Environ Manage. 2017 May 1;192:48-56. doi: 10.1016/j.jenvman.2017.01.033. Epub 2017 Jan 28.


Lattice Boltzmann simulations of the bead-spring microswimmer with a responsive stroke-from an individual to swarms.

Pickl K, Pande J, Köstler H, Rüde U, Smith AS.

J Phys Condens Matter. 2017 Mar 29;29(12):124001. doi: 10.1088/1361-648X/aa5a40. Epub 2017 Jan 18.


Human iPSC-derived cardiomyocytes and tissue engineering strategies for disease modeling and drug screening.

Smith AS, Macadangdang J, Leung W, Laflamme MA, Kim DH.

Biotechnol Adv. 2017 Jan - Feb;35(1):77-94. doi: 10.1016/j.biotechadv.2016.12.002. Epub 2016 Dec 20. Review.


Limits of Applicability of the Voronoi Tessellation Determined by Centers of Cell Nuclei to Epithelium Morphology.

Kaliman S, Jayachandran C, Rehfeldt F, Smith AS.

Front Physiol. 2016 Nov 25;7:551. eCollection 2016.


Aerogel Cherenkov detector for characterizing the intense flash x-ray source, Cygnus, spectrum.

Kim Y, Herrmann HW, McEvoy AM, Young CS, Hamilton C, Schwellenbach DD, Malone RM, Kaufman MI, Smith AS.

Rev Sci Instrum. 2016 Nov;87(11):11E723.


Creating Interactions between Tissue-Engineered Skeletal Muscle and the Peripheral Nervous System.

Smith AS, Passey SL, Martin NR, Player DJ, Mudera V, Greensmith L, Lewis MP.

Cells Tissues Organs. 2016;202(3-4):143-158. Epub 2016 Nov 9.


Nanometric thermal fluctuations of weakly confined biomembranes measured with microsecond time-resolution.

Monzel C, Schmidt D, Seifert U, Smith AS, Merkel R, Sengupta K.

Soft Matter. 2016 May 25;12(21):4755-68. doi: 10.1039/c6sm00412a.


Muscular dystrophy in a dish: engineered human skeletal muscle mimetics for disease modeling and drug discovery.

Smith AST, Davis J, Lee G, Mack DL, Kim DH.

Drug Discov Today. 2016 Sep;21(9):1387-1398. doi: 10.1016/j.drudis.2016.04.013. Epub 2016 Apr 22. Review.


Corrigendum: Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake.

Nakajima K, Cui Z, Li C, Meister J, Cui Y, Fu O, Smith AS, Jain S, Lowell BB, Krashes MJ, Wess J.

Nat Commun. 2016 Mar 3;7:11019. doi: 10.1038/ncomms11019. No abstract available.


Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues.

Mengsteab PY, Uto K, Smith AS, Frankel S, Fisher E, Nawas Z, Macadangdang J, Ebara M, Kim DH.

Biomaterials. 2016 Apr;86:1-10. doi: 10.1016/j.biomaterials.2016.01.062. Epub 2016 Feb 4.


Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells.

Carson D, Hnilova M, Yang X, Nemeth CL, Tsui JH, Smith AS, Jiao A, Regnier M, Murry CE, Tamerler C, Kim DH.

ACS Appl Mater Interfaces. 2016 Aug 31;8(34):21923-32. doi: 10.1021/acsami.5b11671. Epub 2016 Feb 11.


Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs.

Oleaga C, Bernabini C, Smith AS, Srinivasan B, Jackson M, McLamb W, Platt V, Bridges R, Cai Y, Santhanam N, Berry B, Najjar S, Akanda N, Guo X, Martin C, Ekman G, Esch MB, Langer J, Ouedraogo G, Cotovio J, Breton L, Shuler ML, Hickman JJ.

Sci Rep. 2016 Feb 3;6:20030. doi: 10.1038/srep20030.


Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake.

Nakajima K, Cui Z, Li C, Meister J, Cui Y, Fu O, Smith AS, Jain S, Lowell BB, Krashes MJ, Wess J.

Nat Commun. 2016 Jan 8;7:10268. doi: 10.1038/ncomms10268. Erratum in: Nat Commun. 2016;7:11019.


Targeted activation of the hippocampal CA2 area strongly enhances social memory.

Smith AS, Williams Avram SK, Cymerblit-Sabba A, Song J, Young WS.

Mol Psychiatry. 2016 Aug;21(8):1137-44. doi: 10.1038/mp.2015.189. Epub 2016 Jan 5.


Computer Simulations Imply Forelimb-Dominated Underwater Flight in Plesiosaurs.

Liu S, Smith AS, Gu Y, Tan J, Liu CK, Turk G.

PLoS Comput Biol. 2015 Dec 18;11(12):e1004605. doi: 10.1371/journal.pcbi.1004605. eCollection 2015 Dec.


Measuring fast stochastic displacements of bio-membranes with dynamic optical displacement spectroscopy.

Monzel C, Schmidt D, Kleusch C, Kirchenbüchler D, Seifert U, Smith AS, Sengupta K, Merkel R.

Nat Commun. 2015 Oct 6;6:8162. doi: 10.1038/ncomms9162.


Local oxytocin tempers anxiety by activating GABAA receptors in the hypothalamic paraventricular nucleus.

Smith AS, Tabbaa M, Lei K, Eastham P, Butler MJ, Linton L, Altshuler R, Liu Y, Wang Z.

Psychoneuroendocrinology. 2016 Jan;63:50-8. doi: 10.1016/j.psyneuen.2015.09.017. Epub 2015 Sep 21.


Charcot-Marie-Tooth Disease Type 4H Resulting from Compound Heterozygous Mutations in FGD4 from Nonconsanguineous Korean Families.

Hyun YS, Lee J, Kim HJ, Hong YB, Koo H, Smith AS, Kim DH, Choi BO, Chung KW.

Ann Hum Genet. 2015 Nov;79(6):460-9. doi: 10.1111/ahg.12134. Epub 2015 Sep 24.


Nanopatterned Human iPSC-based Model of a Dystrophin-Null Cardiomyopathic Phenotype.

Macadangdang J, Guan X, Smith AS, Lucero R, Czerniecki S, Childers MK, Mack DL, Kim DH.

Cell Mol Bioeng. 2015 Sep;8(3):320-332.


Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems.

Berry BJ, Akanda N, Smith AS, Long CJ, Schnepper MT, Guo X, Hickman JJ.

Biotechnol Prog. 2015 Nov-Dec;31(6):1613-22. doi: 10.1002/btpr.2160. Epub 2015 Sep 11.


Complementary Molecular Dynamics and X-ray Reflectivity Study of an Imidazolium-Based Ionic Liquid at a Neutral Sapphire Interface.

Brkljača Z, Klimczak M, Miličević Z, Weisser M, Taccardi N, Wasserscheid P, Smith DM, Magerl A, Smith AS.

J Phys Chem Lett. 2015 Feb 5;6(3):549-55. doi: 10.1021/jz5024493. Epub 2015 Jan 26.


Crowding of receptors induces ring-like adhesions in model membranes.

Schmidt D, Bihr T, Fenz S, Merkel R, Seifert U, Sengupta K, Smith AS.

Biochim Biophys Acta. 2015 Nov;1853(11 Pt B):2984-91. doi: 10.1016/j.bbamcr.2015.05.025. Epub 2015 May 28.


Forces and shapes as determinants of micro-swimming: effect on synchronisation and the utilisation of drag.

Pande J, Smith AS.

Soft Matter. 2015 Mar 28;11(12):2364-71. doi: 10.1039/c4sm02611j.


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