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Items: 1 to 50 of 58

1.

Detecting molecular forms of antithrombin by LC-MRM-MS: defining the measurands.

Ruhaak LR, Romijn FPHTM, Smit NPM, van der Laarse A, Pieterse MM, de Maat MPM, Haas FJLM, Kluft C, Amiral J, Meijer P, Cobbaert CM.

Clin Chem Lab Med. 2018 May 1. pii: /j/cclm.ahead-of-print/cclm-2017-1111/cclm-2017-1111.xml. doi: 10.1515/cclm-2017-1111. [Epub ahead of print]

PMID:
29708875
2.

Robust and Accurate 2-Year Performance of a Quantitative Mass Spectrometry-Based Apolipoprotein Test in a Clinical Chemistry Laboratory.

Ruhaak LR, Smit NPM, Romijn FPHTM, Pieterse MM, van der Laarse A, van der Burgt YEM, Cobbaert CM.

Clin Chem. 2018 Apr;64(4):747-749. doi: 10.1373/clinchem.2017.285098. Epub 2018 Jan 29. No abstract available.

PMID:
29378689
3.

Automated Multiplex LC-MS/MS Assay for Quantifying Serum Apolipoproteins A-I, B, C-I, C-II, C-III, and E with Qualitative Apolipoprotein E Phenotyping.

van den Broek I, Romijn FP, Nouta J, van der Laarse A, Drijfhout JW, Smit NP, van der Burgt YE, Cobbaert CM.

Clin Chem. 2016 Jan;62(1):188-97. doi: 10.1373/clinchem.2015.246702. Epub 2015 Nov 19.

4.

Quantification of serum apolipoproteins A-I and B-100 in clinical samples using an automated SISCAPA-MALDI-TOF-MS workflow.

van den Broek I, Nouta J, Razavi M, Yip R, Bladergroen MR, Romijn FP, Smit NP, Drews O, Paape R, Suckau D, Deelder AM, van der Burgt YE, Pearson TW, Anderson NL, Cobbaert CM.

Methods. 2015 Jun 15;81:74-85. doi: 10.1016/j.ymeth.2015.03.001. Epub 2015 Mar 9.

PMID:
25766926
5.

Quantifying protein measurands by peptide measurements: where do errors arise?

van den Broek I, Romijn FP, Smit NP, van der Laarse A, Drijfhout JW, van der Burgt YE, Cobbaert CM.

J Proteome Res. 2015 Feb 6;14(2):928-42. doi: 10.1021/pr5011179. Epub 2015 Jan 6.

PMID:
25494833
6.

Metrological traceability in mass spectrometry-based targeted protein quantitation: a proof-of-principle study for serum apolipoproteins A-I and B100.

Smit NP, Romijn FP, van den Broek I, Drijfhout JW, Haex M, van der Laarse A, van der Burgt YE, Cobbaert CM.

J Proteomics. 2014 Sep 23;109:143-61. doi: 10.1016/j.jprot.2014.06.015. Epub 2014 Jun 25.

PMID:
24972322
7.

Evaluation of interspecimen trypsin digestion efficiency prior to multiple reaction monitoring-based absolute protein quantification with native protein calibrators.

van den Broek I, Smit NP, Romijn FP, van der Laarse A, Deelder AM, van der Burgt YE, Cobbaert CM.

J Proteome Res. 2013 Dec 6;12(12):5760-74. doi: 10.1021/pr400763d. Epub 2013 Nov 13.

PMID:
24168082
8.

Antifibrinolytics attenuate inflammatory gene expression after cardiac surgery.

Later AF, Sitniakowsky LS, van Hilten JA, van de Watering L, Brand A, Smit NP, Klautz RJ.

J Thorac Cardiovasc Surg. 2013 Jun;145(6):1611-6, 1616.e1-4. doi: 10.1016/j.jtcvs.2012.11.042. Epub 2013 Jan 16.

9.

Effects of arsenite and UVA-1 radiation on calcineurin signaling.

Musson RE, Mullenders LH, Smit NP.

Mutat Res. 2012 Jul 1;735(1-2):32-8. doi: 10.1016/j.mrfmmm.2012.04.007. Epub 2012 May 4.

PMID:
22564430
10.

Molecular diagnostics of calcineurin-related pathologies.

Musson RE, Cobbaert CM, Smit NP.

Clin Chem. 2012 Mar;58(3):511-22. doi: 10.1373/clinchem.2011.167296. Epub 2011 Oct 20. Review.

11.

Coat color dilution in mice because of inactivation of the melanoma antigen MART-1.

Aydin IT, Hummler E, Smit NP, Beermann F.

Pigment Cell Melanoma Res. 2012 Jan;25(1):37-46. doi: 10.1111/j.1755-148X.2011.00910.x. Epub 2011 Oct 7.

PMID:
21943097
12.

The effect of RBC transfusions on cytokine gene expression after cardiac surgery in patients developing post-operative multiple organ failure.

Sitniakowsky LS, Later AF, van de Watering LM, Bogaerts M, Brand A, Klautz RJ, Smit NP, van Hilten JA.

Transfus Med. 2011 Aug;21(4):236-46. doi: 10.1111/j.1365-3148.2011.01075.x. Epub 2011 Apr 24.

PMID:
21518046
13.

Potent cytotoxic effects of Calomeria amaranthoides on ovarian cancers.

van Haaften C, Duke CC, Weerheim AM, Smit NP, van Haard PM, Darroudi F, Trimbos BJ.

J Exp Clin Cancer Res. 2011 Mar 14;30:29. doi: 10.1186/1756-9966-30-29.

14.

UVA1 radiation inhibits calcineurin through oxidative damage mediated by photosensitization.

Musson RE, Hensbergen PJ, Westphal AH, Temmink WP, Deelder AM, van Pelt J, Mullenders LH, Smit NP.

Free Radic Biol Med. 2011 May 15;50(10):1392-9. doi: 10.1016/j.freeradbiomed.2011.02.019. Epub 2011 Feb 24.

PMID:
21354304
15.

Regulatory mechanisms of calcineurin phosphatase activity.

Musson RE, Smit NP.

Curr Med Chem. 2011;18(2):301-15. Review.

PMID:
21110798
16.

A spectrophotometric assay for routine measurement of mammalian target of rapamycin activity in cell lysates.

Dekter HE, Romijn FP, Temmink WP, van Pelt J, de Fijter JW, Smit NP.

Anal Biochem. 2010 Aug;403(1-2):79-87. doi: 10.1016/j.ab.2010.04.022. Epub 2010 Apr 24.

PMID:
20417611
17.

Everolimus and sirolimus antagonize tacrolimus based calcineurin inhibition via competition for FK-binding protein 12.

van Rossum HH, Romijn FP, Smit NP, de Fijter JW, van Pelt J.

Biochem Pharmacol. 2009 Apr 1;77(7):1206-12. doi: 10.1016/j.bcp.2008.12.009. Epub 2008 Dec 30.

PMID:
19154728
18.

Non-transferrin bound iron measurement is influenced by chelator concentration.

Kolb AM, Smit NP, Lentz-Ljuboje R, Osanto S, van Pelt J.

Anal Biochem. 2009 Feb 1;385(1):13-9. doi: 10.1016/j.ab.2008.11.003. Epub 2008 Nov 7.

PMID:
19026979
19.

Increased melanogenesis is a risk factor for oxidative DNA damage--study on cultured melanocytes and atypical nevus cells.

Smit NP, van Nieuwpoort FA, Marrot L, Out C, Poorthuis B, van Pelt H, Meunier JR, Pavel S.

Photochem Photobiol. 2008 May-Jun;84(3):550-5. doi: 10.1111/j.1751-1097.2007.00242.x.

PMID:
18435613
20.

Variation in leukocyte subset concentrations affects calcineurin activity measurement: implications for pharmacodynamic monitoring strategies.

van Rossum HH, Romijn FP, Sellar KJ, Smit NP, van der Boog PJ, de Fijter JW, van Pelt J.

Clin Chem. 2008 Mar;54(3):517-24. doi: 10.1373/clinchem.2007.097253. Epub 2008 Jan 24.

21.

Calcineurin activity and inhibition in skin and (epi)dermal cell cultures.

Smit NP, Van Rossum HH, Romijn FP, Sellar KJ, Breetveld M, Gibbs S, Van Pelt J.

J Invest Dermatol. 2008 Jul;128(7):1686-90. doi: 10.1038/sj.jid.5701244. Epub 2008 Jan 17.

22.

Spectrophotometric assay for calcineurin activity in leukocytes isolated from human blood.

Sellar KJ, van Rossum HH, Romijn FP, Smit NP, de Fijter JW, van Pelt J.

Anal Biochem. 2006 Nov 1;358(1):104-10. Epub 2006 Aug 24.

PMID:
16979577
23.

Ultraviolet-A (UVA-1) radiation suppresses immunoglobulin production of activated B lymphocytes in vitro.

Polderman MC, van Kooten C, Smit NP, Kamerling SW, Pavel S.

Clin Exp Immunol. 2006 Sep;145(3):528-34.

24.

Mechanistic studies of melanogenesis: the influence of N-substitution on dopamine quinone cyclization.

Borovansky J, Edge R, Land EJ, Navaratnam S, Pavel S, Ramsden CA, Riley PA, Smit NP.

Pigment Cell Res. 2006 Apr;19(2):170-8.

PMID:
16524433
25.

Glutamate receptors on human melanocytes regulate the expression of MiTF.

Hoogduijn MJ, Hitchcock IS, Smit NP, Gillbro JM, Schallreuter KU, Genever PG.

Pigment Cell Res. 2006 Feb;19(1):58-67.

PMID:
16420247
26.

Expression and function of the apoptosis effector Apaf-1 in melanoma.

Peltenburg LT, de Bruin EC, Meersma D, Smit NP, Schrier PI, Medema JP.

Cell Death Differ. 2005 Jun;12(6):678-9. No abstract available.

27.

[Risk factors for skin melanoma: genetic factors probably more important than exposure to sunlight].

Pavel S, Smit NP.

Ned Tijdschr Geneeskd. 2004 Nov 13;148(46):2267-72. Review. Dutch.

PMID:
15584541
28.

Disturbed melanin synthesis and chronic oxidative stress in dysplastic naevi.

Pavel S, van Nieuwpoort F, van der Meulen H, Out C, Pizinger K, Cetkovská P, Smit NP, Koerten HK.

Eur J Cancer. 2004 Jun;40(9):1423-30.

PMID:
15177503
29.

Tyrosine-induced melanogenesis shows differences in morphologic and melanogenic preferences of melanosomes from light and dark skin types.

van Nieuwpoort F, Smit NP, Kolb R, van der Meulen H, Koerten H, Pavel S.

J Invest Dermatol. 2004 May;122(5):1251-5.

30.

Biochemical characterization of a new melanoma model--the minipig MeLiM strain.

Borovanský J, Horák V, Elleder M, Fortýn K, Smit NP, Kolb AM.

Melanoma Res. 2003 Dec;13(6):543-8.

PMID:
14646615
31.

p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: possible implications for melanoma progression.

Sviderskaya EV, Gray-Schopfer VC, Hill SP, Smit NP, Evans-Whipp TJ, Bond J, Hill L, Bataille V, Peters G, Kipling D, Wynford-Thomas D, Bennett DC.

J Natl Cancer Inst. 2003 May 21;95(10):723-32.

PMID:
12759390
32.

Homozygous germline mutation of CDKN2A/p16 and glucose-6-phosphate dehydrogenase deficiency in a multiple melanoma case.

Pavel S, Smit NP, van der Meulen H, Kolb RM, de Groot AJ, van der Velden PA, Gruis NA, Bergman W.

Melanoma Res. 2003 Apr;13(2):171-8.

PMID:
12690301
33.

Melanin has a role in Ca2+ homeostasis in human melanocytes.

Hoogduijn MJ, Smit NP, van der Laarse A, van Nieuwpoort AF, Wood JM, Thody AJ.

Pigment Cell Res. 2003 Apr;16(2):127-32.

PMID:
12622789
34.

Keratinocytes control the pheo/eumelanin ratio in cultured normal human melanocytes.

Duval C, Smit NP, Kolb AM, Régnier M, Pavel S, Schmidt R.

Pigment Cell Res. 2002 Dec;15(6):440-6.

PMID:
12453186
35.

Ligand-dependent activation of the melanocortin 5 receptor: cAMP production and ryanodine receptor-dependent elevations of [Ca(2+)](I).

Hoogduijn MJ, McGurk S, Smit NP, Nibbering PH, Ancans J, van der Laarse A, Thody AJ.

Biochem Biophys Res Commun. 2002 Jan 18;290(2):844-50.

PMID:
11785979
36.

Melanin offers protection against induction of cyclobutane pyrimidine dimers and 6-4 photoproducts by UVB in cultured human melanocytes.

Smit NP, Vink AA, Kolb RM, Steenwinkel MJ, van den Berg PT, van Nieuwpoort F, Roza L, Pavel S.

Photochem Photobiol. 2001 Sep;74(3):424-30.

PMID:
11594056
37.

Melanin content of cultured human melanocytes and UV-induced cytotoxicity.

De Leeuw SM, Smit NP, Van Veldhoven M, Pennings EM, Pavel S, Simons JW, Schothorst AA.

J Photochem Photobiol B. 2001 Aug 30;61(3):106-13.

PMID:
11535409
38.

Melanosomal pH controls rate of melanogenesis, eumelanin/phaeomelanin ratio and melanosome maturation in melanocytes and melanoma cells.

Ancans J, Tobin DJ, Hoogduijn MJ, Smit NP, Wakamatsu K, Thody AJ.

Exp Cell Res. 2001 Aug 1;268(1):26-35.

PMID:
11461115
39.

Study of DT-diaphorase in pigment-producing cells.

Smit NP, Hoogduijn MJ, Riley PA, Pavel S.

Cell Mol Biol (Noisy-le-grand). 1999 Nov;45(7):1041-6.

PMID:
10644008
40.

(Pheo)melanin photosensitizes UVA-induced DNA damage in cultured human melanocytes.

Wenczl E, Van der Schans GP, Roza L, Kolb RM, Timmerman AJ, Smit NP, Pavel S, Schothorst AA.

J Invest Dermatol. 1998 Oct;111(4):678-82.

41.

Variations in melanin formation by cultured melanocytes from different skin types.

Smit NP, Kolb RM, Lentjes EG, Noz KC, van der Meulen H, Koerten HK, Vermeer BJ, Pavel S.

Arch Dermatol Res. 1998 Jun;290(6):342-9.

PMID:
9705167
42.

Cytotoxic interactions of Zn2+ in vitro: melanoma cells are more susceptible than melanocytes.

Borovanský J, Blasko M, Siracký J, Schothorst AA, Smit NP, Pavel S.

Melanoma Res. 1997 Dec;7(6):449-53.

PMID:
9464616
43.

Melanogenesis in cultured melanocytes can be substantially influenced by L-tyrosine and L-cysteine.

Smit NP, Van der Meulen H, Koerten HK, Kolb RM, Mommaas AM, Lentjes EG, Pavel S.

J Invest Dermatol. 1997 Dec;109(6):796-800.

44.

Determination of pheomelanin by measurement of aminohydroxyphenylalanine isomers with high-performance liquid chromatography.

Kolb AM, Lentjes EG, Smit NP, Schothorst A, Vermeer BJ, Pavel S.

Anal Biochem. 1997 Oct 15;252(2):293-8.

PMID:
9344416
45.

Evidence of the indirect formation of the catecholic intermediate substrate responsible for the autoactivation kinetics of tyrosinase.

Cooksey CJ, Garratt PJ, Land EJ, Pavel S, Ramsden CA, Riley PA, Smit NP.

J Biol Chem. 1997 Oct 17;272(42):26226-35.

46.

Melanogenesis in transfected fibroblasts induces lysosomal activation.

Borovanský J, Mommaas AM, Smit NP, Eygendaal D, Winder AJ, Vermeer BJ, Pavel S.

Arch Dermatol Res. 1997 Feb;289(3):145-50.

PMID:
9128762
47.

Loss of adhesion to basement membrane components but not to keratinocytes in proliferating melanocytes.

Danen EH, Jansen KF, Klein CE, Smit NP, Ruiter DJ, van Muijen GN.

Eur J Cell Biol. 1996 May;70(1):69-75.

PMID:
8738421
48.

Metabolic interference of melanogenesis in pigment cells.

Pavel S, Smit NP.

Sb Lek. 1996;97(1):29-39. Review.

PMID:
8711416
49.

Induction of cytotoxicity in melanoma cells through inhibition of catechol-O-methyltransferase.

Smit NP, Pavel S.

Biochem Pharmacol. 1995 Dec 22;50(12):1955-62. Review. No abstract available.

PMID:
8849320
50.

Some aspects of melanin formation of melanocytes cultured on collagen-coated microcarrier beads.

Smit NP, Westerhof W, Smit W, Nanninga B, Pavel S.

Pigment Cell Res. 1995 Apr;8(2):89-96.

PMID:
7659682

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