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Items: 1 to 50 of 912

1.

Osimertinib treatment for patients with EGFR exon 20 mutation positive non-small cell lung cancer.

van Veggel B, Madeira R Santos JFV, Hashemi SMS, Paats MS, Monkhorst K, Heideman DAM, Groves M, Radonic T, Smit EF, Schuuring E, van der Wekken AJ, de Langen AJ.

Lung Cancer. 2019 Dec 20;141:9-13. doi: 10.1016/j.lungcan.2019.12.013. [Epub ahead of print]

PMID:
31926441
2.

Effects of checkpoint inhibitors in advanced non-small cell lung cancer at population level from the National Immunotherapy Registry.

Smit HJM, Aerts J, van den Heuvel M, Hiltermann TJN, Bahce I, Smit EF, Dingemans AC, Hendriks LE, Stigt JA, Schramel FMNH, van Tinteren H, Groen HJM; all participants of NVALT Immunotherapy Register (see addendum).

Lung Cancer. 2019 Dec 28;140:107-112. doi: 10.1016/j.lungcan.2019.12.011. [Epub ahead of print]

PMID:
31911323
3.

Tumour growth rate as a tool for response evaluation during PD-1 treatment for non-small cell lung cancer: a retrospective analysis.

Ten Berge DMHJ, Hurkmans DP, den Besten I, Kloover JS, Mathijssen RHJ, Debets RJEMA, Smit EF, Aerts JGJV.

ERJ Open Res. 2019 Dec 16;5(4). pii: 00179-2019. doi: 10.1183/23120541.00179-2019. eCollection 2019 Oct.

4.

Perceived Discrimination and Trajectories of C-Reactive Protein: The Jackson Heart Study.

Sims KD, Sims M, Glover LM, Smit E, Odden MC.

Am J Prev Med. 2019 Dec 10. pii: S0749-3797(19)30428-3. doi: 10.1016/j.amepre.2019.09.019. [Epub ahead of print]

PMID:
31831294
5.

Customization in mobile health apps: explaining effects on physical activity intentions by the need for autonomy.

Bol N, Høie NM, Nguyen MH, Smit ES.

Digit Health. 2019 Nov 10;5:2055207619888074. doi: 10.1177/2055207619888074. eCollection 2019 Jan-Dec.

6.

Brigatinib in Crizotinib-Refractory ALK+ Non-Small Cell Lung Cancer: 2-Year Follow-up on Systemic and Intracranial Outcomes in the Phase 2 ALTA Trial.

Huber RM, Hansen KH, Paz-Ares Rodríguez L, West HL, Reckamp KL, Leighl NB, Tiseo M, Smit EF, Kim DW, Gettinger SN, Hochmair MJ, Kim SW, Langer CJ, Ahn MJ, Kim ES, Kerstein D, Groen HJM, Camidge DR.

J Thorac Oncol. 2019 Nov 19. pii: S1556-0864(19)33645-7. doi: 10.1016/j.jtho.2019.11.004. [Epub ahead of print]

7.

Correction: Clonality analysis of pulmonary tumors by genome-wide copy number profiling.

Vincenten JPL, van Essen HF, Lissenberg-Witte BI, Bulkmans NWJ, Krijgsman O, Sie D, Eijk PP, Smit EF, Ylstra B, Thunnissen E.

PLoS One. 2019 Nov 19;14(11):e0225733. doi: 10.1371/journal.pone.0225733. eCollection 2019.

8.

Health-related quality of life after prophylactic cranial irradiation for stage III non-small cell lung cancer patients: Results from the NVALT-11/DLCRG-02 phase III study.

Witlox WJA, Ramaekers BLT, Joore MA, Dingemans AC, Praag J, Belderbos J, Tissing-Tan C, Herder G, Haitjema T, Ubbels JF, Lagerwaard J, El Sharouni SY, Stigt JA, Smit EF, van Tinteren H, van der Noort V, Groen HJM, De Ruysscher DKM.

Radiother Oncol. 2019 Nov 13;144:65-71. doi: 10.1016/j.radonc.2019.10.016. [Epub ahead of print]

PMID:
31733490
9.

DLL3 expression in large cell neuroendocrine carcinoma (LCNEC) and association with molecular subtypes and neuroendocrine profile.

Hermans BCM, Derks JL, Thunnissen E, van Suylen RJ, den Bakker MA, Groen HJM, Smit EF, Damhuis RA, van den Broek EC; PALGA-group, Ruland A, Speel EJM, Dingemans AMC.

Lung Cancer. 2019 Dec;138:102-108. doi: 10.1016/j.lungcan.2019.10.010. Epub 2019 Oct 13.

PMID:
31678831
10.

Identifying the Most Autonomy-Supportive Message Frame in Digital Health Communication: A 2x2 Between-Subjects Experiment.

Smit ES, Zeidler C, Resnicow K, de Vries H.

J Med Internet Res. 2019 Oct 30;21(10):e14074. doi: 10.2196/14074.

11.

Pan-cancer whole-genome analyses of metastatic solid tumours.

Priestley P, Baber J, Lolkema MP, Steeghs N, de Bruijn E, Shale C, Duyvesteyn K, Haidari S, van Hoeck A, Onstenk W, Roepman P, Voda M, Bloemendal HJ, Tjan-Heijnen VCG, van Herpen CML, Labots M, Witteveen PO, Smit EF, Sleijfer S, Voest EE, Cuppen E.

Nature. 2019 Nov;575(7781):210-216. doi: 10.1038/s41586-019-1689-y. Epub 2019 Oct 23.

12.

ALK immunohistochemistry positive, FISH negative NSCLC is infrequent, but associated with impaired survival following treatment with crizotinib.

Thunnissen E, Lissenberg-Witte BI, van den Heuvel MM, Monkhorst K, Skov BG, Sørensen JB, Mellemgaard A, Dingemans AMC, Speel EJM, de Langen AJ, Hashemi SMS, Bahce I, van der Drift MA, Looijen-Salamon MG, Gosney J, Postmus PE, Samii SMS, Duplaquet F, Weynand B, Durando X, Penault-Llorca F, Finn S, Grady AO, Oz B, Akyurek N, Buettner R, Wolf J, Bubendorf L, Duin S, Marondel I, Heukamp LC, Timens W, Schuuring EMD, Pauwels P, Smit EF.

Lung Cancer. 2019 Dec;138:13-18. doi: 10.1016/j.lungcan.2019.09.023. Epub 2019 Oct 3.

PMID:
31630043
13.

Functional genomic screen in mesothelioma reveals that loss of function of BRCA1-associated-protein-1 induces chemoresistance to ribonucleotide reductase inhibition.

Okonska A, Bühler S, Rao V, Ronner M, Blijlevens M, van der Meulen-Muileman IH, de Menezes RX, Wipplinger M, Oehl K, Smit EF, Weder W, Stahel RA, Penengo L, van Beusechem VW, Felley-Bosco E.

Mol Cancer Ther. 2019 Oct 16. pii: molcanther.0356.2019. doi: 10.1158/1535-7163.MCT-19-0356. [Epub ahead of print]

PMID:
31619462
14.

Clonality analysis of pulmonary tumors by genome-wide copy number profiling.

Vincenten JPL, van Essen HF, Lissenberg-Witte BI, Bulkmans NWJ, Krijgsman O, Sie D, Eijk PP, Smit EF, Ylstra B, Thunnissen E.

PLoS One. 2019 Oct 16;14(10):e0223827. doi: 10.1371/journal.pone.0223827. eCollection 2019. Erratum in: PLoS One. 2019 Nov 19;14(11):e0225733.

15.

The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.

van der Velden DL, Hoes LR, van der Wijngaart H, van Berge Henegouwen JM, van Werkhoven E, Roepman P, Schilsky RL, de Leng WWJ, Huitema ADR, Nuijen B, Nederlof PM, van Herpen CML, de Groot DJA, Devriese LA, Hoeben A, de Jonge MJA, Chalabi M, Smit EF, de Langen AJ, Mehra N, Labots M, Kapiteijn E, Sleijfer S, Cuppen E, Verheul HMW, Gelderblom H, Voest EE.

Nature. 2019 Oct;574(7776):127-131. doi: 10.1038/s41586-019-1600-x. Epub 2019 Sep 30.

PMID:
31570881
16.

Definition of Synchronous Oligometastatic Non-Small Cell Lung Cancer-A Consensus Report.

Dingemans AC, Hendriks LEL, Berghmans T, Levy A, Hasan B, Faivre-Finn C, Giaj-Levra M, Giaj-Levra N, Girard N, Greillier L, Lantuéjoul S, Edwards J, O'Brien M, Reck M, Smit EF, Van Schil P, Postmus PE, Ramella S, Lievens Y, Gaga M, Peled N, Scagliotti GV, Senan S, Paz-Ares L, Guckenberger M, McDonald F, Ekman S, Cufer T, Gietema H, Infante M, Dziadziuszko R, Peters S, Porta RR, Vansteenkiste J, Dooms C, de Ruysscher D, Besse B, Novello S.

J Thorac Oncol. 2019 Dec;14(12):2109-2119. doi: 10.1016/j.jtho.2019.07.025. Epub 2019 Aug 6.

PMID:
31398540
17.

An economic evaluation of a computer-tailored e-learning program to promote smoking cessation counseling guideline adherence among practice nurses.

de Ruijter D, Hoving C, Evers S, Hudales R, de Vries H, Smit E.

Patient Educ Couns. 2019 Oct;102(10):1802-1811. doi: 10.1016/j.pec.2019.07.015. Epub 2019 Jul 30.

PMID:
31395391
18.

Cancer patients' needs for support in expressing instrumental concerns and emotions.

Linn AJ, van der Goot MJ, Brandes K, van Weert JCM, Smit EG.

Eur J Cancer Care (Engl). 2019 Nov;28(6):e13138. doi: 10.1111/ecc.13138. Epub 2019 Aug 7.

PMID:
31392806
19.

Psycho-Social Effects of Father-Daughter Incest: Views of South African Social Workers.

Gqgabi RB, Smit EI.

J Child Sex Abus. 2019 Oct;28(7):840-859. doi: 10.1080/10538712.2019.1581870. Epub 2019 Aug 5.

PMID:
31381495
20.

Randomised phase 3 study of adjuvant chemotherapy with or without nadroparin in patients with completely resected non-small-cell lung cancer: the NVALT-8 study.

Groen HJM, van der Heijden EHFM, Klinkenberg TJ, Biesma B, Aerts J, Verhagen A, Kloosterziel C, Pieterman R, van den Borne B, Smit HJM, Hoekstra O, Schramel FMNH, van der Noort V, van Tinteren H, Smit EF, Dingemans AC; NVALT Study Group, the Netherlands.

Br J Cancer. 2019 Aug;121(5):372-377. doi: 10.1038/s41416-019-0533-3. Epub 2019 Jul 24.

PMID:
31337877
21.

Perception of affect in unfamiliar musical chords.

Smit EA, Milne AJ, Dean RT, Weidemann G.

PLoS One. 2019 Jun 21;14(6):e0218570. doi: 10.1371/journal.pone.0218570. eCollection 2019.

22.

The prognostic value of early onset, CT derived loss of muscle and adipose tissue during chemotherapy in metastatic non-small cell lung cancer.

Degens JHRJ, Sanders KJC, de Jong EEC, Groen HJM, Smit EF, Aerts JG, Schols AMWJ, Dingemans AC.

Lung Cancer. 2019 Jul;133:130-135. doi: 10.1016/j.lungcan.2019.05.021. Epub 2019 May 20.

23.

Iodine Maps from Subtraction CT or Dual-Energy CT to Detect Pulmonary Emboli with CT Angiography: A Multiple-Observer Study.

Grob D, Smit E, Prince J, Kist J, Stöger L, Geurts B, Snoeren MM, van Dijk R, Oostveen LJ, Prokop M, Schaefer-Prokop CM, Sechopoulos I, Brink M.

Radiology. 2019 Jul;292(1):197-205. doi: 10.1148/radiol.2019182666. Epub 2019 May 14.

PMID:
31084482
24.

Arsenic exposure and serum antibody concentrations to diphtheria and tetanus toxoid in children at age 5: A prospective birth cohort in Bangladesh.

Welch BM, Branscum A, Ahmed SM, Hystad P, Smit E, Afroz S, Megowan M, Golam M, Ibne Hasan MOS, Rahman ML, Quamruzzaman Q, Christiani DC, Kile ML.

Environ Int. 2019 Jun;127:810-818. doi: 10.1016/j.envint.2019.04.015. Epub 2019 Apr 30.

25.

Baseline bio-accumulation concentrations and resulting oxidative stress in Synodontis zambezensis after an acute laboratory exposure to 4,4'-DDT.

Volschenk CM, Ikenaka Y, Yohannes YB, Nakayama SM, Ishizuka M, Smit E, van Vuren JHJ, Greenfield R.

Pestic Biochem Physiol. 2019 May;156:44-55. doi: 10.1016/j.pestbp.2019.02.005. Epub 2019 Feb 6.

PMID:
31027580
26.

Human Herpes-8 virus copy to cell ratio: A diagnostic tool in primary effusion lymphoma.

Carne S, Smit E, Price N, Paul J, Guiver M, Tedder R.

J Clin Virol. 2019 Jul;116:7-10. doi: 10.1016/j.jcv.2019.03.013. Epub 2019 Mar 22.

PMID:
30991238
27.

Safety and Efficacy of Crizotinib in Patients With Advanced or Metastatic ROS1-Rearranged Lung Cancer (EUCROSS): A European Phase II Clinical Trial.

Michels S, Massutí B, Schildhaus HU, Franklin J, Sebastian M, Felip E, Grohé C, Rodriguez-Abreu D, Abdulla DSY, Bischoff H, Brandts C, Carcereny E, Corral J, Dingemans AC, Pereira E, Fassunke J, Fischer RN, Gardizi M, Heukamp L, Insa A, Kron A, Menon R, Persigehl T, Reck M, Riedel R, Rothschild SI, Scheel AH, Scheffler M, Schmalz P, Smit EF, Limburg M, Provencio M, Karachaliou N, Merkelbach-Bruse S, Hellmich M, Nogova L, Büttner R, Rosell R, Wolf J.

J Thorac Oncol. 2019 Jul;14(7):1266-1276. doi: 10.1016/j.jtho.2019.03.020. Epub 2019 Apr 9.

PMID:
30978502
28.

Pembrolizumab for all PD-L1-positive NSCLC.

Smit EF, de Langen AJ.

Lancet. 2019 May 4;393(10183):1776-1778. doi: 10.1016/S0140-6736(18)32559-5. Epub 2019 Apr 4. No abstract available.

PMID:
30955976
29.

Food insecurity and physical functioning limitations among older U.S. adults.

Jackson JA, Branscum A, Tang A, Smit E.

Prev Med Rep. 2019 Feb 18;14:100829. doi: 10.1016/j.pmedr.2019.100829. eCollection 2019 Jun.

30.

Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions.

Hummelink K, Muller M, Linders TC, van der Noort V, Nederlof PM, Baas P, Burgers S, Smit EF, Meijer GA, van den Heuvel MM, van den Broek D, Monkhorst K.

ERJ Open Res. 2019 Mar 25;5(1). pii: 00016-2019. doi: 10.1183/23120541.00016-2019. eCollection 2019 Feb.

31.

Stepped care targeting psychological distress in head and neck cancer and lung cancer patients: which groups specifically benefit? Secondary analyses of a randomized controlled trial.

Jansen F, Lissenberg-Witte BI, Krebber AMH, Cuijpers P, de Bree R, Becker-Commissaris A, Smit EF, van Straten A, Eeckhout GM, Beekman ATF, Leemans CR, Verdonck-de Leeuw IM.

Support Care Cancer. 2019 Dec;27(12):4543-4553. doi: 10.1007/s00520-019-04714-3. Epub 2019 Mar 27.

32.

How to make the best use of immunotherapy as first-line treatment of advanced/metastatic non-small-cell lung cancer.

Peters S, Reck M, Smit EF, Mok T, Hellmann MD.

Ann Oncol. 2019 Jun 1;30(6):884-896. doi: 10.1093/annonc/mdz109.

PMID:
30912805
33.

"I was Right about Vaccination": Confirmation Bias and Health Literacy in Online Health Information Seeking.

Meppelink CS, Smit EG, Fransen ML, Diviani N.

J Health Commun. 2019;24(2):129-140. doi: 10.1080/10810730.2019.1583701. Epub 2019 Mar 21.

PMID:
30895889
34.

Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers.

Trebeschi S, Drago SG, Birkbak NJ, Kurilova I, Cǎlin AM, Delli Pizzi A, Lalezari F, Lambregts DMJ, Rohaan MW, Parmar C, Rozeman EA, Hartemink KJ, Swanton C, Haanen JBAG, Blank CU, Smit EF, Beets-Tan RGH, Aerts HJWL.

Ann Oncol. 2019 Jun 1;30(6):998-1004. doi: 10.1093/annonc/mdz108.

35.

Prevalence and prognostic value of PD-L1 expression in molecular subtypes of metastatic large cell neuroendocrine carcinoma (LCNEC).

Hermans BCM, Derks JL, Thunnissen E, van Suylen RJ, den Bakker MA, Groen HJM, Smit EF, Damhuis RA, van den Broek EC, Stallinga CM, Roemen GM, Speel EJM, Dingemans AC; PALGA-group.

Lung Cancer. 2019 Apr;130:179-186. doi: 10.1016/j.lungcan.2019.02.022. Epub 2019 Feb 21.

PMID:
30885341
36.

Image Quality of Iodine Maps for Pulmonary Embolism: A Comparison of Subtraction CT and Dual-Energy CT.

Grob D, Smit E, Oostveen LJ, Snoeren MM, Prokop M, Schaefer-Prokop CM, Sechopoulos I, Brink M.

AJR Am J Roentgenol. 2019 Mar 12:1-7. doi: 10.2214/AJR.18.20786. [Epub ahead of print]

PMID:
30860897
37.

Should or could? Testing the use of autonomy-supportive language and the provision of choice in online computer-tailored alcohol reduction communication.

Altendorf MB, van Weert JCM, Hoving C, Smit ES.

Digit Health. 2019 Feb 27;5:2055207619832767. doi: 10.1177/2055207619832767. eCollection 2019 Jan-Dec.

38.

Afatinib in NSCLC With HER2 Mutations: Results of the Prospective, Open-Label Phase II NICHE Trial of European Thoracic Oncology Platform (ETOP).

Dziadziuszko R, Smit EF, Dafni U, Wolf J, Wasąg B, Biernat W, Finn SP, Kammler R, Tsourti Z, Rabaglio M, Ruepp B, Roschitzki-Voser H, Stahel RA, Felip E, Peters S.

J Thorac Oncol. 2019 Jun;14(6):1086-1094. doi: 10.1016/j.jtho.2019.02.017. Epub 2019 Feb 27.

PMID:
30825613
39.

Repeatability of [18F]FDG PET/CT total metabolic active tumour volume and total tumour burden in NSCLC patients.

Kolinger GD, Vállez García D, Kramer GM, Frings V, Smit EF, de Langen AJ, Dierckx RAJO, Hoekstra OS, Boellaard R.

EJNMMI Res. 2019 Feb 7;9(1):14. doi: 10.1186/s13550-019-0481-1.

40.

Partial-volume correction in dynamic PET-CT: effect on tumor kinetic parameter estimation and validation of simplified metrics.

Cysouw MCF, Golla SVS, Frings V, Smit EF, Hoekstra OS, Kramer GM, Boellaard R; QuIC-ConCePT Consortium.

EJNMMI Res. 2019 Feb 4;9(1):12. doi: 10.1186/s13550-019-0483-z.

41.

Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Planchard D, Popat S, Kerr K, Novello S, Smit EF, Faivre-Finn C, Mok TS, Reck M, Van Schil PE, Hellmann MD, Peters S.

Ann Oncol. 2019 May 1;30(5):863-870. doi: 10.1093/annonc/mdy474. No abstract available.

PMID:
30715168
42.

Proteome analysis of non-small cell lung cancer cell line secretomes and patient sputum reveals biofluid biomarker candidates for cisplatin response prediction.

Böttger F, Schaaij-Visser TB, de Reus I, Piersma SR, Pham TV, Nagel R, Brakenhoff RH, Thunnissen E, Smit EF, Jimenez CR.

J Proteomics. 2019 Mar 30;196:106-119. doi: 10.1016/j.jprot.2019.01.018. Epub 2019 Jan 30.

PMID:
30710758
43.

High-throughput RNAi screening reveals cancer-selective lethal targets in the RNA spliceosome.

Blijlevens M, van der Meulen-Muileman IH, de Menezes RX, Smit EF, van Beusechem VW.

Oncogene. 2019 May;38(21):4142-4153. doi: 10.1038/s41388-019-0711-z. Epub 2019 Jan 31.

PMID:
30705407
44.

Long-term expanding human airway organoids for disease modeling.

Sachs N, Papaspyropoulos A, Zomer-van Ommen DD, Heo I, Böttinger L, Klay D, Weeber F, Huelsz-Prince G, Iakobachvili N, Amatngalim GD, de Ligt J, van Hoeck A, Proost N, Viveen MC, Lyubimova A, Teeven L, Derakhshan S, Korving J, Begthel H, Dekkers JF, Kumawat K, Ramos E, van Oosterhout MF, Offerhaus GJ, Wiener DJ, Olimpio EP, Dijkstra KK, Smit EF, van der Linden M, Jaksani S, van de Ven M, Jonkers J, Rios AC, Voest EE, van Moorsel CH, van der Ent CK, Cuppen E, van Oudenaarden A, Coenjaerts FE, Meyaard L, Bont LJ, Peters PJ, Tans SJ, van Zon JS, Boj SF, Vries RG, Beekman JM, Clevers H.

EMBO J. 2019 Feb 15;38(4). pii: e100300. doi: 10.15252/embj.2018100300. Epub 2019 Jan 14.

45.

Induction of Peripheral Effector CD8 T-cell Proliferation by Combination of Paclitaxel, Carboplatin, and Bevacizumab in Non-small Cell Lung Cancer Patients.

de Goeje PL, Poncin M, Bezemer K, Kaijen-Lambers MEH, Groen HJM, Smit EF, Dingemans AC, Kunert A, Hendriks RW, Aerts JGJV.

Clin Cancer Res. 2019 Apr 1;25(7):2219-2227. doi: 10.1158/1078-0432.CCR-18-2243. Epub 2019 Jan 14.

PMID:
30642911
46.

Position of a panel of international lung cancer experts on the approval decision for use of durvalumab in stage III non-small-cell lung cancer (NSCLC) by the Committee for Medicinal Products for Human Use (CHMP).

Peters S, Dafni U, Boyer M, De Ruysscher D, Faivre-Finn C, Felip E, Garrido P, Girard N, Guckenberger M, Haanen J, Le Pechoux C, Mornex F, Ozsahin M, Paz-Ares L, Planchard D, Raben D, Ramalingam S, Reck M, Smit E, Stahel R, Stenzinger A, Swanton C, Vallone S, Garassino MC.

Ann Oncol. 2019 Feb 1;30(2):161-165. doi: 10.1093/annonc/mdy553. No abstract available.

PMID:
30624547
47.

Goal-setting in geriatric rehabilitation: a systematic review and meta-analysis.

Smit EB, Bouwstra H, Hertogh CM, Wattel EM, van der Wouden JC.

Clin Rehabil. 2019 Mar;33(3):395-407. doi: 10.1177/0269215518818224. Epub 2018 Dec 12.

48.

Outcomes and costs of single-step hepatitis C testing in primary care, Birmingham, United Kingdom.

Munang M, Smit E, Barnett T, Atherton C, Tahir M, Atabani SF.

Public Health. 2019 Jan;166:40-44. doi: 10.1016/j.puhe.2018.09.024.

PMID:
30448691
49.

Measurement Properties of the Barthel Index in Geriatric Rehabilitation.

Bouwstra H, Smit EB, Wattel EM, van der Wouden JC, Hertogh CMPM, Terluin B, Terwee CB.

J Am Med Dir Assoc. 2019 Apr;20(4):420-425.e1. doi: 10.1016/j.jamda.2018.09.033. Epub 2018 Nov 16.

PMID:
30448338
50.

The effects of persuasive messages on cancer patients' attitudes, norms and intention to express concerns.

Brandes K, Linn AJ, van Weert JCM, Verdam MGE, Smit EG.

Patient Educ Couns. 2019 Mar;102(3):443-451. doi: 10.1016/j.pec.2018.10.031. Epub 2018 Nov 2.

PMID:
30448042

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