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Items: 1 to 50 of 309

1.

Early restoration of parvalbumin interneuron activity prevents memory loss and network hyperexcitability in a mouse model of Alzheimer's disease.

Hijazi S, Heistek TS, Scheltens P, Neumann U, Shimshek DR, Mansvelder HD, Smit AB, van Kesteren RE.

Mol Psychiatry. 2019 Aug 20. doi: 10.1038/s41380-019-0483-4. [Epub ahead of print]

PMID:
31431685
2.

The autism- and schizophrenia-associated protein CYFIP1 regulates bilateral brain connectivity and behaviour.

Domínguez-Iturza N, Lo AC, Shah D, Armendáriz M, Vannelli A, Mercaldo V, Trusel M, Li KW, Gastaldo D, Santos AR, Callaerts-Vegh Z, D'Hooge R, Mameli M, Van der Linden A, Smit AB, Achsel T, Bagni C.

Nat Commun. 2019 Aug 1;10(1):3454. doi: 10.1038/s41467-019-11203-y.

3.

SALM1 controls synapse development by promoting F-actin/PIP2-dependent Neurexin clustering.

Brouwer M, Farzana F, Koopmans F, Chen N, Brunner JW, Oldani S, Li KW, van Weering JR, Smit AB, Toonen RF, Verhage M.

EMBO J. 2019 Aug 1:e101289. doi: 10.15252/embj.2018101289. [Epub ahead of print]

PMID:
31368584
4.

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse.

Koopmans F, van Nierop P, Andres-Alonso M, Byrnes A, Cijsouw T, Coba MP, Cornelisse LN, Farrell RJ, Goldschmidt HL, Howrigan DP, Hussain NK, Imig C, de Jong APH, Jung H, Kohansalnodehi M, Kramarz B, Lipstein N, Lovering RC, MacGillavry H, Mariano V, Mi H, Ninov M, Osumi-Sutherland D, Pielot R, Smalla KH, Tang H, Tashman K, Toonen RFG, Verpelli C, Reig-Viader R, Watanabe K, van Weering J, Achsel T, Ashrafi G, Asi N, Brown TC, De Camilli P, Feuermann M, Foulger RE, Gaudet P, Joglekar A, Kanellopoulos A, Malenka R, Nicoll RA, Pulido C, de Juan-Sanz J, Sheng M, Südhof TC, Tilgner HU, Bagni C, Bayés À, Biederer T, Brose N, Chua JJE, Dieterich DC, Gundelfinger ED, Hoogenraad C, Huganir RL, Jahn R, Kaeser PS, Kim E, Kreutz MR, McPherson PS, Neale BM, O'Connor V, Posthuma D, Ryan TA, Sala C, Feng G, Hyman SE, Thomas PD, Smit AB, Verhage M.

Neuron. 2019 Jul 17;103(2):217-234.e4. doi: 10.1016/j.neuron.2019.05.002. Epub 2019 Jun 3.

PMID:
31171447
5.

Transcriptome and proteome profiling of neural stem cells from the human subventricular zone in Parkinson's disease.

Donega V, Burm SM, van Strien ME, van Bodegraven EJ, Paliukhovich I, Geut H, van de Berg WDJ, Li KW, Smit AB, Basak O, Hol EM.

Acta Neuropathol Commun. 2019 Jun 3;7(1):84. doi: 10.1186/s40478-019-0736-0. Erratum in: Acta Neuropathol Commun. 2019 Aug 14;7(1):131.

6.

Combined cellomics and proteomics analysis reveals shared neuronal morphology and molecular pathway phenotypes for multiple schizophrenia risk genes.

Rosato M, Stringer S, Gebuis T, Paliukhovich I, Li KW, Posthuma D, Sullivan PF, Smit AB, van Kesteren RE.

Mol Psychiatry. 2019 May 29. doi: 10.1038/s41380-019-0436-y. [Epub ahead of print]

PMID:
31142819
7.

Memory strength gates the involvement of a CREB-dependent cortical fear engram in remote memory.

Matos MR, Visser E, Kramvis I, van der Loo RJ, Gebuis T, Zalm R, Rao-Ruiz P, Mansvelder HD, Smit AB, van den Oever MC.

Nat Commun. 2019 May 24;10(1):2315. doi: 10.1038/s41467-019-10266-1.

8.

A Fast and Economical Sample Preparation Protocol for Interaction Proteomics Analysis.

Gonzalez-Lozano MA, Koopmans F, Paliukhovich I, Smit AB, Li KW.

Proteomics. 2019 May;19(9):e1900027. doi: 10.1002/pmic.201900027. Epub 2019 Apr 18.

PMID:
30864274
9.

Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.

Jansen PR, Watanabe K, Stringer S, Skene N, Bryois J, Hammerschlag AR, de Leeuw CA, Benjamins JS, Muñoz-Manchado AB, Nagel M, Savage JE, Tiemeier H, White T; 23andMe Research Team, Tung JY, Hinds DA, Vacic V, Wang X, Sullivan PF, van der Sluis S, Polderman TJC, Smit AB, Hjerling-Leffler J, Van Someren EJW, Posthuma D.

Nat Genet. 2019 Mar;51(3):394-403. doi: 10.1038/s41588-018-0333-3. Epub 2019 Feb 25.

PMID:
30804565
10.

Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays.

Otvos RA, Still KBM, Somsen GW, Smit AB, Kool J.

SLAS Discov. 2019 Mar;24(3):362-385. doi: 10.1177/2472555218822098. Epub 2019 Jan 25.

11.

A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms.

Arias-Vásquez A, Groffen AJ, Spijker S, Ouwens KG, Klein M, Vojinovic D, Galesloot TE, Bralten J, Hottenga JJ, van der Most PJ, Kattenberg VM, Pool R, Nolte IM, Penninx BWJH, Fedko IO, Dolan CV, Nivard MG, den Braber A, van Duijn CM, Hoekstra PJ, Buitelaar JK, Kiemeney LA, Hoogman M, Middeldorp CM, Draisma HHM, Vermeulen SH, Sánchez-Mora C, Ramos-Quiroga JA, Ribasés M; EAGLE-ADHD Consortium, Hartman CA, Kooij JJS, Amin N, Smit AB, Franke B, Boomsma DI.

Behav Genet. 2019 May;49(3):270-285. doi: 10.1007/s10519-018-09947-2. Epub 2019 Jan 18.

PMID:
30659475
12.

Stress vulnerability promotes an alcohol-prone phenotype in a preclinical model of sustained depression.

Riga D, Schmitz LJM, van Mourik Y, Hoogendijk WJG, De Vries TJ, Smit AB, Spijker S.

Addict Biol. 2018 Dec 18. doi: 10.1111/adb.12701. [Epub ahead of print]

PMID:
30561063
13.

Comparative Hippocampal Synaptic Proteomes of Rodents and Primates: Differences in Neuroplasticity-Related Proteins.

Koopmans F, Pandya NJ, Franke SK, Phillippens IHCMH, Paliukhovich I, Li KW, Smit AB.

Front Mol Neurosci. 2018 Oct 2;11:364. doi: 10.3389/fnmol.2018.00364. eCollection 2018.

14.

Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells.

Gupta I, Collier PG, Haase B, Mahfouz A, Joglekar A, Floyd T, Koopmans F, Barres B, Smit AB, Sloan SA, Luo W, Fedrigo O, Ross ME, Tilgner HU.

Nat Biotechnol. 2018 Oct 15. doi: 10.1038/nbt.4259. [Epub ahead of print]

PMID:
30320766
15.

Proteomics of neurodegenerative diseases: analysis of human post-mortem brain.

Li KW, Ganz AB, Smit AB.

J Neurochem. 2018 Oct 5. doi: 10.1111/jnc.14603. [Epub ahead of print] Review.

PMID:
30289976
16.

Noelin1 Affects Lateral Mobility of Synaptic AMPA Receptors.

Pandya NJ, Seeger C, Babai N, Gonzalez-Lozano MA, Mack V, Lodder JC, Gouwenberg Y, Mansvelder HD, Danielson UH, Li KW, Heine M, Spijker S, Frischknecht R, Smit AB.

Cell Rep. 2018 Jul 31;24(5):1218-1230. doi: 10.1016/j.celrep.2018.06.102.

17.

Neuropathology and cognitive performance in self-reported cognitively healthy centenarians.

Ganz AB, Beker N, Hulsman M, Sikkes S, Netherlands Brain Bank, Scheltens P, Smit AB, Rozemuller AJM, Hoozemans JJM, Holstege H.

Acta Neuropathol Commun. 2018 Jul 23;6(1):64. doi: 10.1186/s40478-018-0558-5.

18.

Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer's disease.

Hondius DC, Eigenhuis KN, Morrema THJ, van der Schors RC, van Nierop P, Bugiani M, Li KW, Hoozemans JJM, Smit AB, Rozemuller AJM.

Acta Neuropathol Commun. 2018 Jun 4;6(1):46. doi: 10.1186/s40478-018-0540-2.

19.

Author Correction: Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS.

Taskesen E, Mishra A, van der Sluis S, Ferrari R; International FTD-Genomics Consortium, Veldink JH, van Es MA, Smit AB, Posthuma D, Pijnenburg Y.

Sci Rep. 2018 May 14;8(1):7789. doi: 10.1038/s41598-018-21308-x.

20.

Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling.

Slagboom J, Otvos RA, Cardoso FC, Iyer J, Visser JC, van Doodewaerd BR, McCleary RJR, Niessen WMA, Somsen GW, Lewis RJ, Kini RM, Smit AB, Casewell NR, Kool J.

Toxicon. 2018 Jun 15;148:213-222. doi: 10.1016/j.toxicon.2018.04.022. Epub 2018 May 4.

21.

Correction: The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory.

Schmitz LJM, Klaassen RV, Ruiperez-Alonso M, Zamri AE, Stroeder J, Rao-Ruiz P, Lodder JC, van der Loo RJ, Mansvelder HD, Smit AB, Spijker S.

Elife. 2018 May 4;7. pii: e36711. doi: 10.7554/eLife.36711. No abstract available.

22.

MIR137 schizophrenia-associated locus controls synaptic function by regulating synaptogenesis, synapse maturation and synaptic transmission.

He E, Lozano MAG, Stringer S, Watanabe K, Sakamoto K, den Oudsten F, Koopmans F, Giamberardino SN, Hammerschlag A, Cornelisse LN, Li KW, van Weering J, Posthuma D, Smit AB, Sullivan PF, Verhage M.

Hum Mol Genet. 2018 Jun 1;27(11):1879-1891. doi: 10.1093/hmg/ddy089.

23.

Treatment of Phonological Disorder: A Feasibility Study With Focus on Outcome Measures.

Smit AB, Brumbaugh KM, Weltsch B, Hilgers M.

Am J Speech Lang Pathol. 2018 May 3;27(2):536-552. doi: 10.1044/2017_AJSLP-16-0225.

PMID:
29466550
24.

A Laser Microdissection-Liquid Chromatography-Tandem Mass Spectrometry Workflow for Post-mortem Analysis of Brain Tissue.

Hondius DC, Hoozemans JJM, Rozemuller AJM, Li KW, Smit AB.

Methods Mol Biol. 2018;1723:371-383. doi: 10.1007/978-1-4939-7558-7_21.

PMID:
29344872
25.

Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats.

Riga D, Kramvis I, Koskinen MK, van Bokhoven P, van der Harst JE, Heistek TS, Jaap Timmerman A, van Nierop P, van der Schors RC, Pieneman AW, de Weger A, van Mourik Y, Schoffelmeer ANM, Mansvelder HD, Meredith RM, Hoogendijk WJG, Smit AB, Spijker S.

Sci Transl Med. 2017 Dec 20;9(421). pii: eaai8753. doi: 10.1126/scitranslmed.aai8753.

PMID:
29263233
26.

Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders.

Nguyen HT, Bryois J, Kim A, Dobbyn A, Huckins LM, Munoz-Manchado AB, Ruderfer DM, Genovese G, Fromer M, Xu X, Pinto D, Linnarsson S, Verhage M, Smit AB, Hjerling-Leffler J, Buxbaum JD, Hultman C, Sklar P, Purcell SM, Lage K, He X, Sullivan PF, Stahl EA.

Genome Med. 2017 Dec 20;9(1):114. doi: 10.1186/s13073-017-0497-y.

27.

The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory.

Schmitz LJM, Klaassen RV, Ruiperez-Alonso M, Zamri AE, Stroeder J, Rao-Ruiz P, Lodder JC, van der Loo RJ, Mansvelder HD, Smit AB, Spijker S.

Elife. 2017 Dec 4;6. pii: e24192. doi: 10.7554/eLife.24192. Erratum in: Elife. 2018 May 04;7:.

28.

Comparative Analyses of Data Independent Acquisition Mass Spectrometric Approaches: DIA, WiSIM-DIA, and Untargeted DIA.

Koopmans F, Ho JTC, Smit AB, Li KW.

Proteomics. 2018 Jan;18(1). doi: 10.1002/pmic.201700304.

29.

Correlation profiling of brain sub-cellular proteomes reveals co-assembly of synaptic proteins and subcellular distribution.

Pandya NJ, Koopmans F, Slotman JA, Paliukhovich I, Houtsmuller AB, Smit AB, Li KW.

Sci Rep. 2017 Sep 21;7(1):12107. doi: 10.1038/s41598-017-11690-3.

30.

Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease.

Korecka JA, Moloney EB, Eggers R, Hobo B, Scheffer S, Ras-Verloop N, Pasterkamp RJ, Swaab DF, Smit AB, van Kesteren RE, Bossers K, Verhaagen J.

J Neurosci. 2017 Sep 27;37(39):9361-9379. doi: 10.1523/JNEUROSCI.0084-17.2017. Epub 2017 Aug 21.

31.

Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS.

Taskesen E, Mishra A, van der Sluis S, Ferrari R; International FTD-Genomics Consortium, Veldink JH, van Es MA, Smit AB, Posthuma D, Pijnenburg Y.

Sci Rep. 2017 Aug 21;7(1):8899. doi: 10.1038/s41598-017-09320-z. Erratum in: Sci Rep. 2018 May 14;8(1):7789.

32.

High Content Analysis of Hippocampal Neuron-Astrocyte Co-cultures Shows a Positive Effect of Fortasyn Connect on Neuronal Survival and Postsynaptic Maturation.

van Deijk AF, Broersen LM, Verkuyl JM, Smit AB, Verheijen MHG.

Front Neurosci. 2017 Aug 4;11:440. doi: 10.3389/fnins.2017.00440. eCollection 2017.

33.

Temporal profiling of depression vulnerability in a preclinical model of sustained depression.

Riga D, Schmitz LJM, Hoogendijk WJG, Smit AB, Spijker S.

Sci Rep. 2017 Aug 17;7(1):8570. doi: 10.1038/s41598-017-06984-5.

34.

Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains.

Geerts CJ, Mancini R, Chen N, Koopmans FTW, Li KW, Smit AB, van Weering JRT, Verhage M, Groffen AJA.

PLoS One. 2017 Jul 26;12(7):e0180912. doi: 10.1371/journal.pone.0180912. eCollection 2017.

35.

Multi-level characterization of balanced inhibitory-excitatory cortical neuron network derived from human pluripotent stem cells.

Nadadhur AG, Emperador Melero J, Meijer M, Schut D, Jacobs G, Li KW, Hjorth JJJ, Meredith RM, Toonen RF, Van Kesteren RE, Smit AB, Verhage M, Heine VM.

PLoS One. 2017 Jun 6;12(6):e0178533. doi: 10.1371/journal.pone.0178533. eCollection 2017.

36.

Age-Dependent Protein Aggregation Initiates Amyloid-β Aggregation.

Groh N, Bühler A, Huang C, Li KW, van Nierop P, Smit AB, Fändrich M, Baumann F, David DC.

Front Aging Neurosci. 2017 May 17;9:138. doi: 10.3389/fnagi.2017.00138. eCollection 2017.

37.

Oligodendroglial myelination requires astrocyte-derived lipids.

Camargo N, Goudriaan A, van Deijk AF, Otte WM, Brouwers JF, Lodder H, Gutmann DH, Nave KA, Dijkhuizen RM, Mansvelder HD, Chrast R, Smit AB, Verheijen MHG.

PLoS Biol. 2017 May 26;15(5):e1002605. doi: 10.1371/journal.pbio.1002605. eCollection 2017 May.

38.

Gene-set analysis shows association between FMRP targets and autism spectrum disorder.

Jansen A, Dieleman GC, Smit AB, Verhage M, Verhulst FC, Polderman TJC, Posthuma D.

Eur J Hum Genet. 2017 Jun;25(7):863-868. doi: 10.1038/ejhg.2017.55. Epub 2017 Apr 19.

39.

AHCODA-DB: a data repository with web-based mining tools for the analysis of automated high-content mouse phenomics data.

Koopmans B, Smit AB, Verhage M, Loos M.

BMC Bioinformatics. 2017 Apr 4;18(1):200. doi: 10.1186/s12859-017-1612-1.

40.

A one-week 5-choice serial reaction time task to measure impulsivity and attention in adult and adolescent mice.

Remmelink E, Chau U, Smit AB, Verhage M, Loos M.

Sci Rep. 2017 Feb 15;7:42519. doi: 10.1038/srep42519.

41.

Astrocyte lipid metabolism is critical for synapse development and function in vivo.

van Deijk AF, Camargo N, Timmerman J, Heistek T, Brouwers JF, Mogavero F, Mansvelder HD, Smit AB, Verheijen MH.

Glia. 2017 Apr;65(4):670-682. doi: 10.1002/glia.23120. Epub 2017 Feb 7.

PMID:
28168742
42.

Complex Genetics of Behavior: BXDs in the Automated Home-Cage.

Loos M, Verhage M, Spijker S, Smit AB.

Methods Mol Biol. 2017;1488:519-530.

PMID:
27933542
43.

Measuring discrimination- and reversal learning in mouse models within 4 days and without prior food deprivation.

Remmelink E, Smit AB, Verhage M, Loos M.

Learn Mem. 2016 Oct 17;23(11):660-667. doi: 10.1101/lm.042085.116. Print 2016 Nov.

44.

Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development.

Gonzalez-Lozano MA, Klemmer P, Gebuis T, Hassan C, van Nierop P, van Kesteren RE, Smit AB, Li KW.

Sci Rep. 2016 Oct 17;6:35456. doi: 10.1038/srep35456.

45.

Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex.

Pandya NJ, Klaassen RV, van der Schors RC, Slotman JA, Houtsmuller A, Smit AB, Li KW.

Proteomics. 2016 Oct;16(20):2698-2705. doi: 10.1002/pmic.201500400. Epub 2016 Sep 12.

46.

Cognitive flexibility deficits in a mouse model for the absence of full-length dystrophin.

Remmelink E, Aartsma-Rus A, Smit AB, Verhage M, Loos M, van Putten M.

Genes Brain Behav. 2016 Jul;15(6):558-67. doi: 10.1111/gbb.12301.

47.

Functional characterisation of human synaptic genes expressed in the Drosophila brain.

Zografos L, Tang J, Hesse F, Wanker EE, Li KW, Smit AB, Davies RW, Armstrong JD.

Biol Open. 2016 May 15;5(5):662-7. doi: 10.1242/bio.016261.

48.

Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1.

Schmitz SK, King C, Kortleven C, Huson V, Kroon T, Kevenaar JT, Schut D, Saarloos I, Hoetjes JP, de Wit H, Stiedl O, Spijker S, Li KW, Mansvelder HD, Smit AB, Cornelisse LN, Verhage M, Toonen RF.

EMBO J. 2016 Jun 1;35(11):1236-50. doi: 10.15252/embj.201592244. Epub 2016 Apr 7.

49.

Development of an Online Cell-Based Bioactivity Screening Method by Coupling Liquid Chromatography to Flow Cytometry with Parallel Mass Spectrometry.

Otvos RA, van Nierop P, Niessen WM, Kini RM, Somsen GW, Smit AB, Kool J.

Anal Chem. 2016 May 3;88(9):4825-32. doi: 10.1021/acs.analchem.6b00455. Epub 2016 Apr 20.

PMID:
27046509
50.

Individual and Familial Susceptibility to MPTP in a Common Marmoset Model for Parkinson's Disease.

Franke SK, van Kesteren RE, Hofman S, Wubben JA, Smit AB, Philippens IH.

Neurodegener Dis. 2016;16(5-6):293-303. doi: 10.1159/000442574. Epub 2016 Mar 22.

PMID:
26999593

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