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Items: 49

1.

A Broad Role for Cysteines in Bovine Antibody Diversity.

Haakenson JK, Deiss TC, Warner GF, Mwangi W, Criscitiello MF, Smider VV.

Immunohorizons. 2019 Oct 16;3(10):478-487. doi: 10.4049/immunohorizons.1900058.

PMID:
31619454
2.

Diversity in the Cow Ultralong CDR H3 Antibody Repertoire.

Haakenson JK, Huang R, Smider VV.

Front Immunol. 2018 Jun 4;9:1262. doi: 10.3389/fimmu.2018.01262. eCollection 2018. Review.

3.

The Unusual Genetics and Biochemistry of Bovine Immunoglobulins.

Stanfield RL, Haakenson J, Deiss TC, Criscitiello MF, Wilson IA, Smider VV.

Adv Immunol. 2018;137:135-164. doi: 10.1016/bs.ai.2017.12.004. Epub 2018 Feb 9.

4.

Immunogenetic factors driving formation of ultralong VH CDR3 in Bos taurus antibodies.

Deiss TC, Vadnais M, Wang F, Chen PL, Torkamani A, Mwangi W, Lefranc MP, Criscitiello MF, Smider VV.

Cell Mol Immunol. 2019 Jan;16(1):53-64. doi: 10.1038/cmi.2017.117. Epub 2017 Dec 4.

PMID:
29200193
5.

Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows.

Sok D, Le KM, Vadnais M, Saye-Francisco KL, Jardine JG, Torres JL, Berndsen ZT, Kong L, Stanfield R, Ruiz J, Ramos A, Liang CH, Chen PL, Criscitiello MF, Mwangi W, Wilson IA, Ward AB, Smider VV, Burton DR.

Nature. 2017 Aug 3;548(7665):108-111. doi: 10.1038/nature23301. Epub 2017 Jul 20.

6.

SMI-Ribosome inactivating protein conjugates selectively inhibit tumor cell growth.

Roy S, Axup JY, Forsyth JS, Goswami RK, Hutchins BM, Bajuri KM, Kazane SA, Smider VV, Felding BH, Sinha SC.

Chem Commun (Camb). 2017 Apr 11;53(30):4234-4237. doi: 10.1039/c7cc00745k.

7.

Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.

Stanfield RL, Wilson IA, Smider VV.

Sci Immunol. 2016 Jul;1(1). pii: aaf7962. doi: 10.1126/sciimmunol.aaf7962. Epub 2016 Jul 14.

8.

Bos taurus ultralong CDR H3 antibodies.

Vadnais ML, Smider VV.

Curr Opin Struct Biol. 2016 Jun;38:62-7. doi: 10.1016/j.sbi.2016.05.004. Epub 2016 Jun 10. Review.

9.

Antibody Therapeutics in Oncology.

Wold ED, Smider VV, Felding BH.

Immunotherapy (Los Angel). 2016 Mar;2(1). pii: 108. Epub 2016 Feb 1.

10.

Distinct antibody species: structural differences creating therapeutic opportunities.

Muyldermans S, Smider VV.

Curr Opin Immunol. 2016 Jun;40:7-13. doi: 10.1016/j.coi.2016.02.003. Epub 2016 Feb 27. Review.

11.

Fc-Small Molecule Antibody Mimetics.

Wold ED, Axup JY, Felding BH, Smider VV.

Bioconjug Chem. 2015 Dec 16;26(12):2311-4. doi: 10.1021/acs.bioconjchem.5b00530. Epub 2015 Nov 13.

12.

Structural and genetic diversity in antibody repertoires from diverse species.

de los Rios M, Criscitiello MF, Smider VV.

Curr Opin Struct Biol. 2015 Aug;33:27-41. doi: 10.1016/j.sbi.2015.06.002. Epub 2015 Jul 17. Review.

PMID:
26188469
13.

Antibody conjugates with unnatural amino acids.

Hallam TJ, Wold E, Wahl A, Smider VV.

Mol Pharm. 2015 Jun 1;12(6):1848-62. doi: 10.1021/acs.molpharmaceut.5b00082. Epub 2015 May 21. Review.

PMID:
25898256
14.

Antibody microarrays utilizing site-specific antibody-oligonucleotide conjugates.

Wold ED, McBride R, Axup JY, Kazane SA, Smider VV.

Bioconjug Chem. 2015 May 20;26(5):807-11. doi: 10.1021/acs.bioconjchem.5b00111. Epub 2015 Apr 30.

15.

Unnatural amino acids in novel antibody conjugates.

Hallam TJ, Smider VV.

Future Med Chem. 2014 Jul;6(11):1309-24. doi: 10.4155/fmc.14.79. Review.

PMID:
25163001
16.

A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes.

Furman JL, Kang M, Choi S, Cao Y, Wold ED, Sun SB, Smider VV, Schultz PG, Kim CH.

J Am Chem Soc. 2014 Jun 11;136(23):8411-7. doi: 10.1021/ja502851h. Epub 2014 May 30.

17.

Recruiting cytotoxic T cells to folate-receptor-positive cancer cells.

Kularatne SA, Deshmukh V, Gymnopoulos M, Biroc SL, Xia J, Srinagesh S, Sun Y, Zou N, Shimazu M, Pinkstaff J, Ensari S, Knudsen N, Manibusan A, Axup J, Kim C, Smider V, Javahishvili T, Schultz PG.

Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12101-12104. doi: 10.1002/anie.201306866. Epub 2013 Sep 25. No abstract available.

18.

A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.

Grover RK, Zhu X, Nieusma T, Jones T, Boreo I, MacLeod AS, Mark A, Niessen S, Kim HJ, Kong L, Assad-Garcia N, Kwon K, Chesi M, Smider VV, Salomon DR, Jelinek DF, Kyle RA, Pyles RB, Glass JI, Ward AB, Wilson IA, Lerner RA.

Science. 2014 Feb 7;343(6171):656-661. doi: 10.1126/science.1246135.

19.

Bispecific small molecule-antibody conjugate targeting prostate cancer.

Kim CH, Axup JY, Lawson BR, Yun H, Tardif V, Choi SH, Zhou Q, Dubrovska A, Biroc SL, Marsden R, Pinstaff J, Smider VV, Schultz PG.

Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17796-801. doi: 10.1073/pnas.1316026110. Epub 2013 Oct 14.

20.

Functional antibody CDR3 fusion proteins with enhanced pharmacological properties.

Zhang Y, Wang D, de Lichtervelde L, Sun SB, Smider VV, Schultz PG, Wang F.

Angew Chem Int Ed Engl. 2013 Aug 5;52(32):8295-8. doi: 10.1002/anie.201303656. Epub 2013 Jun 21. No abstract available.

21.

Reshaping antibody diversity.

Wang F, Ekiert DC, Ahmad I, Yu W, Zhang Y, Bazirgan O, Torkamani A, Raudsepp T, Mwangi W, Criscitiello MF, Wilson IA, Schultz PG, Smider VV.

Cell. 2013 Jun 6;153(6):1379-93. doi: 10.1016/j.cell.2013.04.049.

22.

Identification of metal ion binding peptides containing unnatural amino acids by phage display.

Day JW, Kim CH, Smider VV, Schultz PG.

Bioorg Med Chem Lett. 2013 May 1;23(9):2598-600. doi: 10.1016/j.bmcl.2013.02.106. Epub 2013 Mar 7.

PMID:
23541674
23.

Arrayed antibody library technology for therapeutic biologic discovery.

Bentley CA, Bazirgan OA, Graziano JJ, Holmes EM, Smider VV.

Methods. 2013 Mar 15;60(1):91-8. doi: 10.1016/j.ymeth.2013.02.003. Epub 2013 Feb 26.

PMID:
23485577
24.

Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation.

Wang F, Sen S, Zhang Y, Ahmad I, Zhu X, Wilson IA, Smider VV, Magliery TJ, Schultz PG.

Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4261-6. doi: 10.1073/pnas.1301810110. Epub 2013 Feb 25. Retraction in: Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7855.

25.

Self-assembled antibody multimers through peptide nucleic acid conjugation.

Kazane SA, Axup JY, Kim CH, Ciobanu M, Wold ED, Barluenga S, Hutchins BA, Schultz PG, Winssinger N, Smider VV.

J Am Chem Soc. 2013 Jan 9;135(1):340-6. doi: 10.1021/ja309505c. Epub 2012 Dec 21.

26.

Synthesis of site-specific antibody-drug conjugates using unnatural amino acids.

Axup JY, Bajjuri KM, Ritland M, Hutchins BM, Kim CH, Kazane SA, Halder R, Forsyth JS, Santidrian AF, Stafin K, Lu Y, Tran H, Seller AJ, Biroc SL, Szydlik A, Pinkstaff JK, Tian F, Sinha SC, Felding-Habermann B, Smider VV, Schultz PG.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16101-6. doi: 10.1073/pnas.1211023109. Epub 2012 Sep 17.

27.

Electrophoretic mobility shift assays for protein-DNA complexes involved in DNA repair.

Tsai C, Smider V, Hwang BJ, Chu G.

Methods Mol Biol. 2012;920:53-78. doi: 10.1007/978-1-61779-998-3_5.

28.

Synthesis of bispecific antibodies using genetically encoded unnatural amino acids.

Kim CH, Axup JY, Dubrovska A, Kazane SA, Hutchins BA, Wold ED, Smider VV, Schultz PG.

J Am Chem Soc. 2012 Jun 20;134(24):9918-21. doi: 10.1021/ja303904e. Epub 2012 Jun 6.

29.

Arrayed protein library technology for therapeutic biologic discovery.

Mao H, Graziano J, Smider VV.

Biotechnol Genet Eng Rev. 2012;28:131-45. Review. No abstract available.

PMID:
22616485
30.

Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR.

Kazane SA, Sok D, Cho EH, Uson ML, Kuhn P, Schultz PG, Smider VV.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3731-6. doi: 10.1073/pnas.1120682109. Epub 2012 Feb 15.

31.

Selective formation of covalent protein heterodimers with an unnatural amino acid.

Hutchins BM, Kazane SA, Staflin K, Forsyth JS, Felding-Habermann B, Smider VV, Schultz PG.

Chem Biol. 2011 Mar 25;18(3):299-303. doi: 10.1016/j.chembiol.2011.01.006.

32.

Site-specific coupling and sterically controlled formation of multimeric antibody fab fragments with unnatural amino acids.

Hutchins BM, Kazane SA, Staflin K, Forsyth JS, Felding-Habermann B, Schultz PG, Smider VV.

J Mol Biol. 2011 Mar 4;406(4):595-603. doi: 10.1016/j.jmb.2011.01.011. Epub 2011 Jan 13.

33.

Spatially addressed combinatorial protein libraries for recombinant antibody discovery and optimization.

Mao H, Graziano JJ, Chase TM, Bentley CA, Bazirgan OA, Reddy NP, Song BD, Smider VV.

Nat Biotechnol. 2010 Nov;28(11):1195-202. doi: 10.1038/nbt.1694. Epub 2010 Oct 24.

PMID:
20972421
34.

A human germ line antibody light chain with hydrolytic properties associated with multimerization status.

Sharma V, Heriot W, Trisler K, Smider V.

J Biol Chem. 2009 Nov 27;284(48):33079-87. doi: 10.1074/jbc.M109.036087. Epub 2009 Oct 2.

35.

Mutagenesis and evolution of sulfated antibodies using an expanded genetic code.

Liu CC, Choe H, Farzan M, Smider VV, Schultz PG.

Biochemistry. 2009 Sep 22;48(37):8891-8. doi: 10.1021/bi9011429.

36.

Evolution of proteins with genetically encoded "chemical warheads".

Liu CC, Mack AV, Brustad EM, Mills JH, Groff D, Smider VV, Schultz PG.

J Am Chem Soc. 2009 Jul 22;131(28):9616-7. doi: 10.1021/ja902985e.

37.

Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids.

Grünewald J, Hunt GS, Dong L, Niessen F, Wen BG, Tsao ML, Perera R, Kang M, Laffitte BA, Azarian S, Ruf W, Nasoff M, Lerner RA, Schultz PG, Smider VV.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4337-42. doi: 10.1073/pnas.0900507106. Epub 2009 Feb 25.

38.

Protein evolution with an expanded genetic code.

Liu CC, Mack AV, Tsao ML, Mills JH, Lee HS, Choe H, Farzan M, Schultz PG, Smider VV.

Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17688-93. doi: 10.1073/pnas.0809543105. Epub 2008 Nov 11.

39.

Immunochemical termination of self-tolerance.

Grünewald J, Tsao ML, Perera R, Dong L, Niessen F, Wen BG, Kubitz DM, Smider VV, Ruf W, Nasoff M, Lerner RA, Schultz PG.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11276-80. doi: 10.1073/pnas.0804157105. Epub 2008 Aug 6.

40.

A metalloantibody that irreversibly binds a protein antigen.

Trisler K, Looger LL, Sharma V, Baker M, Benson DE, Trauger S, Schultz PG, Smider VV.

J Biol Chem. 2007 Sep 7;282(36):26344-53. Epub 2007 Jul 6.

41.
42.

Co-expression of antibody fab heavy and light chain genes from separate evolved compatible replicons in E. coli.

Leonard B, Sharma V, Smider V.

J Immunol Methods. 2006 Dec 20;317(1-2):56-63. Epub 2006 Oct 4.

PMID:
17049550
43.

Electrophoretic mobility shift assays to study protein binding to damaged DNA.

Smider V, Hwang BJ, Chu G.

Methods Mol Biol. 2006;314:323-44.

PMID:
16673891
44.

Directed evolution and identification of control regions of ColE1 plasmid replication origins using only nucleotide deletions.

Kim D, Rhee Y, Rhodes D, Sharma V, Sorenson O, Greener A, Smider V.

J Mol Biol. 2005 Aug 26;351(4):763-75.

PMID:
16051272
45.

The use of electrophoretic mobility shift assays to study DNA repair.

Hwang BJ, Smider V, Chu G.

Methods Mol Biol. 1999;113:103-20. No abstract available.

PMID:
10443414
46.
47.

The end-joining reaction in V(D)J recombination.

Smider V, Chu G.

Semin Immunol. 1997 Jun;9(3):189-97. Review.

PMID:
9200330
48.

Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants.

Errami A, Smider V, Rathmell WK, He DM, Hendrickson EA, Zdzienicka MZ, Chu G.

Mol Cell Biol. 1996 Apr;16(4):1519-26.

49.

Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA.

Smider V, Rathmell WK, Lieber MR, Chu G.

Science. 1994 Oct 14;266(5183):288-91.

PMID:
7939667

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