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Items: 25

1.

Cyclin C: The Story of a Non-Cycling Cyclin.

Ježek J, Smethurst DGJ, Stieg DC, Kiss ZAC, Hanley SE, Ganesan V, Chang KT, Cooper KF, Strich R.

Biology (Basel). 2019 Jan 4;8(1). pii: E3. doi: 10.3390/biology8010003. Review.

2.

ER fatalities-The role of ER-mitochondrial contact sites in yeast life and death decisions.

Smethurst DGJ, Cooper KF.

Mech Ageing Dev. 2017 Jan;161(Pt B):225-233. doi: 10.1016/j.mad.2016.07.007. Epub 2016 Aug 6. Review.

3.

Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort.

Kvale MN, Hesselson S, Hoffmann TJ, Cao Y, Chan D, Connell S, Croen LA, Dispensa BP, Eshragh J, Finn A, Gollub J, Iribarren C, Jorgenson E, Kushi LH, Lao R, Lu Y, Ludwig D, Mathauda GK, McGuire WB, Mei G, Miles S, Mittman M, Patil M, Quesenberry CP Jr, Ranatunga D, Rowell S, Sadler M, Sakoda LC, Shapero M, Shen L, Shenoy T, Smethurst D, Somkin CP, Van Den Eeden SK, Walter L, Wan E, Webster T, Whitmer RA, Wong S, Zau C, Zhan Y, Schaefer C, Kwok PY, Risch N.

Genetics. 2015 Aug;200(4):1051-60. doi: 10.1534/genetics.115.178905. Epub 2015 Jun 19.

4.

Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort.

Lapham K, Kvale MN, Lin J, Connell S, Croen LA, Dispensa BP, Fang L, Hesselson S, Hoffmann TJ, Iribarren C, Jorgenson E, Kushi LH, Ludwig D, Matsuguchi T, McGuire WB, Miles S, Quesenberry CP Jr, Rowell S, Sadler M, Sakoda LC, Smethurst D, Somkin CP, Van Den Eeden SK, Walter L, Whitmer RA, Kwok PY, Risch N, Schaefer C, Blackburn EH.

Genetics. 2015 Aug;200(4):1061-72. doi: 10.1534/genetics.115.178624. Epub 2015 Jun 19.

5.

Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort.

Banda Y, Kvale MN, Hoffmann TJ, Hesselson SE, Ranatunga D, Tang H, Sabatti C, Croen LA, Dispensa BP, Henderson M, Iribarren C, Jorgenson E, Kushi LH, Ludwig D, Olberg D, Quesenberry CP Jr, Rowell S, Sadler M, Sakoda LC, Sciortino S, Shen L, Smethurst D, Somkin CP, Van Den Eeden SK, Walter L, Whitmer RA, Kwok PY, Schaefer C, Risch N.

Genetics. 2015 Aug;200(4):1285-95. doi: 10.1534/genetics.115.178616. Epub 2015 Jun 19.

6.

Randomized phase Ib/II trial of rilotumumab or ganitumab with panitumumab versus panitumumab alone in patients with wild-type KRAS metastatic colorectal cancer.

Van Cutsem E, Eng C, Nowara E, Swieboda-Sadlej A, Tebbutt NC, Mitchell E, Davidenko I, Stephenson J, Elez E, Prenen H, Deng H, Tang R, McCaffery I, Oliner KS, Chen L, Gansert J, Loh E, Smethurst D, Tabernero J.

Clin Cancer Res. 2014 Aug 15;20(16):4240-50. doi: 10.1158/1078-0432.CCR-13-2752. Epub 2014 Jun 11.

7.

Actin - a biosensor that determines cell fate in yeasts.

Smethurst DG, Dawes IW, Gourlay CW.

FEMS Yeast Res. 2014 Feb;14(1):89-95. doi: 10.1111/1567-1364.12119. Epub 2013 Nov 26. Review.

8.

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma.

Linette GP, Stadtmauer EA, Maus MV, Rapoport AP, Levine BL, Emery L, Litzky L, Bagg A, Carreno BM, Cimino PJ, Binder-Scholl GK, Smethurst DP, Gerry AB, Pumphrey NJ, Bennett AD, Brewer JE, Dukes J, Harper J, Tayton-Martin HK, Jakobsen BK, Hassan NJ, Kalos M, June CH.

Blood. 2013 Aug 8;122(6):863-71. doi: 10.1182/blood-2013-03-490565. Epub 2013 Jun 14.

9.

A pharmacologic perspective on newly emerging T-cell manipulation technologies.

Smethurst D.

Br J Clin Pharmacol. 2013 Aug;76(2):173-87. doi: 10.1111/j.1365-2125.2012.04475.x. Review.

10.

First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: a phase I/II open-label and double-blind study.

Demetri GD, Le Cesne A, Chawla SP, Brodowicz T, Maki RG, Bach BA, Smethurst DP, Bray S, Hei YJ, Blay JY.

Eur J Cancer. 2012 Mar;48(4):547-63. doi: 10.1016/j.ejca.2011.12.008. Epub 2012 Jan 11.

PMID:
22240283
11.

Randomized phase II study of dulanermin in combination with paclitaxel, carboplatin, and bevacizumab in advanced non-small-cell lung cancer.

Soria JC, Márk Z, Zatloukal P, Szima B, Albert I, Juhász E, Pujol JL, Kozielski J, Baker N, Smethurst D, Hei YJ, Ashkenazi A, Stern H, Amler L, Pan Y, Blackhall F.

J Clin Oncol. 2011 Nov 20;29(33):4442-51. doi: 10.1200/JCO.2011.37.2623. Epub 2011 Oct 17.

PMID:
22010015
12.

Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm.

Hoffmann TJ, Zhan Y, Kvale MN, Hesselson SE, Gollub J, Iribarren C, Lu Y, Mei G, Purdy MM, Quesenberry C, Rowell S, Shapero MH, Smethurst D, Somkin CP, Van den Eeden SK, Walter L, Webster T, Whitmer RA, Finn A, Schaefer C, Kwok PY, Risch N.

Genomics. 2011 Dec;98(6):422-30. doi: 10.1016/j.ygeno.2011.08.007. Epub 2011 Aug 28.

13.

Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array.

Hoffmann TJ, Kvale MN, Hesselson SE, Zhan Y, Aquino C, Cao Y, Cawley S, Chung E, Connell S, Eshragh J, Ewing M, Gollub J, Henderson M, Hubbell E, Iribarren C, Kaufman J, Lao RZ, Lu Y, Ludwig D, Mathauda GK, McGuire W, Mei G, Miles S, Purdy MM, Quesenberry C, Ranatunga D, Rowell S, Sadler M, Shapero MH, Shen L, Shenoy TR, Smethurst D, Van den Eeden SK, Walter L, Wan E, Wearley R, Webster T, Wen CC, Weng L, Whitmer RA, Williams A, Wong SC, Zau C, Finn A, Schaefer C, Kwok PY, Risch N.

Genomics. 2011 Aug;98(2):79-89. doi: 10.1016/j.ygeno.2011.04.005. Epub 2011 Apr 30.

14.

Why cosmetic demand will never be satisfied.

Smethurst DP.

J Cosmet Dermatol. 2003 Jul;2(3-4):186-9.

PMID:
17163927
15.

A first-in-man phase I tolerability and pharmacokinetic study of the cyclin-dependent kinase-inhibitor AZD5438 in healthy male volunteers.

Camidge DR, Smethurst D, Growcott J, Barrass NC, Foster JR, Febbraro S, Swaisland H, Hughes A.

Cancer Chemother Pharmacol. 2007 Aug;60(3):391-8. Epub 2006 Nov 18.

PMID:
17115157
16.

Pharmaceutical medicine: making the leap.

Smethurst D.

BMJ. 2003 Nov 22;327(7425):s161-2. No abstract available.

PMID:
14630784
17.

Atopic eczema.

Smethurst D, Macfarlane S.

Clin Evid. 2002 Dec;(8):1664-82. Review. No abstract available.

PMID:
12603963
18.

Atopic eczema.

Smethurst D.

Clin Evid. 2002 Jun;(7):1467-82. Review. No abstract available. Update in: Clin Evid. 2002 Dec;(8):1664-82.

PMID:
12230763
19.

The pharmacoeconomic impact of generics: an evolutionary tale.

Smethurst D.

Expert Opin Pharmacother. 2002 Sep;3(9):1235-8.

PMID:
12186615
20.

Self-regulation in hospital waiting lists.

Smethurst DP, Williams HC.

J R Soc Med. 2002 Jun;95(6):287-9.

21.

Self-regulation in hospital waiting lists.

Smethurst DP, Williams HC.

J R Soc Med. 2002 Apr;95(4):220. No abstract available.

22.

Power laws. Are hospital waiting lists self-regulating?

Smethurst DP, Williams HC.

Nature. 2001 Apr 5;410(6829):652-3. No abstract available.

PMID:
11287943
23.

Percussion--a new way to diagnose a pneumothorax.

Winter R, Smethurst D.

Br J Anaesth. 1999 Dec;83(6):960-1.

24.

Improved manufacture and application of an agarose magnetizable solid-phase support.

Davies MJ, Smethurst DE, Howard KM, Todd M, Higgins LM, Bruce IJ.

Appl Biochem Biotechnol. 1997 Oct-Nov;68(1-2):95-112.

PMID:
9373932
25.

Magnetizable solid-phase supports for purification of nucleic acids.

Bruce IJ, Davies MJ, Howard K, Smethurst DE, Todd M.

J Pharm Pharmacol. 1996 Feb;48(2):147-9.

PMID:
8935162

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