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Items: 33

1.

Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy.

Lu T, Schubert C, Cummings MD, Bignan G, Connolly PJ, Smans K, Ludovici D, Parker MH, Meyer C, Rocaboy C, Alexander R, Grasberger B, De Breucker S, Esser N, Fraiponts E, Gilissen R, Janssens B, Peeters D, Van Nuffel L, Vermeulen P, Bischoff J, Meerpoel L.

Bioorg Med Chem Lett. 2018 Jul 1;28(12):2159-2164. doi: 10.1016/j.bmcl.2018.05.014. Epub 2018 May 8.

PMID:
29779975
2.

Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors.

Bijvelds MJC, Tresadern G, Hellemans A, Smans K, Nieuwenhuijze NDA, Meijsen KF, Bongartz JP, Ver Donck L, de Jonge HR, Schuurkes JAJ, De Maeyer JH.

J Biol Chem. 2018 May 25;293(21):8173-8181. doi: 10.1074/jbc.RA118.002835. Epub 2018 Apr 13.

3.

Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment.

Daniëls VW, Smans K, Royaux I, Chypre M, Swinnen JV, Zaidi N.

PLoS One. 2014 Sep 12;9(9):e106913. doi: 10.1371/journal.pone.0106913. eCollection 2014.

4.

Atypical plasma lipid profile in cancer patients: cause or consequence?

Munir R, Usman H, Hasnain S, Smans K, Kalbacher H, Zaidi N.

Biochimie. 2014 Jul;102:9-18. doi: 10.1016/j.biochi.2014.03.010. Epub 2014 Apr 2. Review.

PMID:
24704108
5.

Lipogenesis and lipolysis: the pathways exploited by the cancer cells to acquire fatty acids.

Zaidi N, Lupien L, Kuemmerle NB, Kinlaw WB, Swinnen JV, Smans K.

Prog Lipid Res. 2013 Oct;52(4):585-9. doi: 10.1016/j.plipres.2013.08.005. Epub 2013 Aug 31. Review.

6.

ATP-citrate lyase: a key player in cancer metabolism.

Zaidi N, Swinnen JV, Smans K.

Cancer Res. 2012 Aug 1;72(15):3709-14. doi: 10.1158/0008-5472.CAN-11-4112. Epub 2012 Jul 10. Review.

7.

ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms.

Zaidi N, Royaux I, Swinnen JV, Smans K.

Mol Cancer Ther. 2012 Sep;11(9):1925-35. doi: 10.1158/1535-7163.MCT-12-0095. Epub 2012 Jun 20.

8.

ATP-citrate lyase: a mini-review.

Chypre M, Zaidi N, Smans K.

Biochem Biophys Res Commun. 2012 May 25;422(1):1-4. doi: 10.1016/j.bbrc.2012.04.144. Epub 2012 May 3. Review.

PMID:
22575446
9.

De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation.

Rysman E, Brusselmans K, Scheys K, Timmermans L, Derua R, Munck S, Van Veldhoven PP, Waltregny D, Daniëls VW, Machiels J, Vanderhoydonc F, Smans K, Waelkens E, Verhoeven G, Swinnen JV.

Cancer Res. 2010 Oct 15;70(20):8117-26. doi: 10.1158/0008-5472.CAN-09-3871. Epub 2010 Sep 28.

10.

Validation of an image simulation technique for two computed radiography systems: an application to neonatal imaging.

Smans K, Vandenbroucke D, Pauwels H, Struelens L, Vanhavere F, Bosmans H.

Med Phys. 2010 May;37(5):2092-100.

PMID:
20527542
11.

Simulation of image detectors in radiology for determination of scatter-to-primary ratios using Monte Carlo radiation transport code MCNP/MCNPX.

Smans K, Zoetelief J, Verbrugge B, Haeck W, Struelens L, Vanhavere F, Bosmans H.

Med Phys. 2010 May;37(5):2082-91.

PMID:
20527541
12.

Cu filtration for dose reduction in neonatal chest imaging.

Smans K, Struelens L, Smet M, Bosmans H, Vanhavere F.

Radiat Prot Dosimetry. 2010 Apr-May;139(1-3):281-6. doi: 10.1093/rpd/ncq061. Epub 2010 Feb 23.

PMID:
20179072
13.

Effective dose analysis of three-dimensional rotational angiography during catheter ablation procedures.

Wielandts JY, Smans K, Ector J, De Buck S, Heidbüchel H, Bosmans H.

Phys Med Biol. 2010 Feb 7;55(3):563-79. doi: 10.1088/0031-9155/55/3/001. Epub 2010 Jan 7.

PMID:
20057012
14.

Experimental validation of Monte Carlo calculations with a voxelized Rando-Alderson phantom: a study on influence parameters.

Struelens L, Vanhavere F, Smans K.

Phys Med Biol. 2008 Oct 21;53(20):5831-44. doi: 10.1088/0031-9155/53/20/018. Epub 2008 Sep 30.

PMID:
18827320
15.

Patient dose in neonatal units.

Smans K, Struelens L, Smet M, Bosmans H, Vanhavere F.

Radiat Prot Dosimetry. 2008;131(1):143-7. doi: 10.1093/rpd/ncn237. Epub 2008 Aug 30.

PMID:
18757900
16.

Calculation of organ doses in x-ray examinations of premature babies.

Smans K, Tapiovaara M, Cannie M, Struelens L, Vanhavere F, Smet M, Bosmans H.

Med Phys. 2008 Feb;35(2):556-68.

PMID:
18383677
17.

A study of the correlation between dose area product and effective dose in vascular radiology.

Smans K, Struelens L, Hoornaert MT, Bleeser F, Buls N, Berus D, Clerinx P, Malchair F, Vanhavere F, Bosmans H.

Radiat Prot Dosimetry. 2008;130(3):300-8. doi: 10.1093/rpd/ncn050. Epub 2008 Feb 29.

PMID:
18310610
18.

Results of a European survey on patient doses in paediatric radiology.

Smans K, Vaño E, Sanchez R, Schultz FW, Zoetelief J, Kiljunen T, Maccia C, Järvinen H, Bly R, Kosunen A, Faulkner K, Bosmans H.

Radiat Prot Dosimetry. 2008;129(1-3):204-10. doi: 10.1093/rpd/ncn031. Epub 2008 Feb 29.

PMID:
18310099
19.

Radiation dose survey in a paediatric cardiac catheterisation laboratory equipped with flat-panel detectors.

Dragusin O, Gewillig M, Desmet W, Smans K, Struelens L, Bosmans H.

Radiat Prot Dosimetry. 2008;129(1-3):91-5. doi: 10.1093/rpd/ncn035. Epub 2008 Feb 18.

PMID:
18285320
20.

Diagnostic reference levels in angiography and interventional radiology: a Belgian multi-centre study.

Bleeser F, Hoornaert MT, Smans K, Struelens L, Buls N, Berus D, Clerinx P, Hambach L, Malchair F, Bosmans H.

Radiat Prot Dosimetry. 2008;129(1-3):50-5. doi: 10.1093/rpd/ncn028. Epub 2008 Feb 18.

PMID:
18283058
21.

Image quality assessment using the CD-DISC phantom for vascular radiology and vascular surgery.

Struelens L, Hambach L, Buls N, Smans K, Malchair F, Hoornaert MT, Vanhavere F, Bosmans H.

Eur J Radiol. 2008 Aug;67(2):348-56. Epub 2007 Sep 10.

PMID:
17826937
22.

Downregulation of two novel genes in Sl/Sld and W(LacZ)/Wv mouse jejunum.

Wouters MM, Neefs JM, Kerchove d'Exaerde Ad, Vanderwinden JM, Smans KA.

Biochem Biophys Res Commun. 2006 Jul 28;346(2):491-500. Epub 2006 Jun 2.

PMID:
16765319
23.

Towards a proposition of a diagnostic (dose) reference level for mammographic acquisitions in breast screening measurements in Belgium.

Smans K, Bosmans H, Xiao M, Carton AK, Marchal G.

Radiat Prot Dosimetry. 2005;117(1-3):321-6. Epub 2006 Feb 7.

PMID:
16464839
24.

Subtractive hybridization unravels a role for the ion cotransporter NKCC1 in the murine intestinal pacemaker.

Wouters M, De Laet A, Donck LV, Delpire E, van Bogaert PP, Timmermans JP, de Kerchove d'Exaerde A, Smans K, Vanderwinden JM.

Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1219-27. Epub 2005 Aug 25.

25.

WZsGreen/+: a new green fluorescent protein knock-in mouse model for the study of KIT-expressing cells in gut and cerebellum.

Wouters M, Smans K, Vanderwinden JM.

Physiol Genomics. 2005 Aug 11;22(3):412-21. Epub 2005 Jun 14.

26.

Transferrin-mediated uptake of aluminium by human parathyroid cells results in reduced parathyroid hormone secretion.

Smans KA, D'Haese PC, Van Landeghem GF, Andries LJ, Lamberts LV, Hendy GN, De Broe ME.

Nephrol Dial Transplant. 2000 Sep;15(9):1328-36.

PMID:
10978387
28.

Bispecific antibody-mediated lysis of primary cultures of ovarian carcinoma cells using multiple target antigens.

Smans KA, Ingvarsson MB, Lindgren P, Canevari S, Walt H, Stigbrand T, Bäckström T, Millán JL.

Int J Cancer. 1999 Oct 8;83(2):270-7.

29.

Is there a link between erythropoietin therapy and adynamic bone disease?

Smans KA, Van Landeghem FG, D'Haese PC, Couttenye MM, De Broe ME.

Nephrol Dial Transplant. 1996 Jul;11(7):1248-9. Review. No abstract available.

PMID:
8672017
30.

Bispecific antibody-mediated lysis of placental and germ cell alkaline phosphatase targeted solid tumors in immunocompetent mice.

Smans KA, Hoylaerts MF, Narisawa S, Millán JL, De Broe ME.

Cancer Res. 1995 Oct 1;55(19):4383-90.

31.

Requirement of monocytes and T-helper cells during development of tumor cell cytotoxicity in targeted T cells.

Smans KA, Hoylaerts MF, De Broe ME.

Cancer Immunol Immunother. 1994 Jan;38(1):43-52.

PMID:
8299118
32.

Transgenic mice expressing the tumor marker germ cell alkaline phosphatase: an in vivo tumor model for human cancer antigens.

Narisawa S, Smans KA, Avis J, Hoylaerts MF, Millán JL.

Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5081-5.

33.

Tumor-cell lysis by in-situ-activated human peripheral-blood mononuclear cells.

Smans KA, Hoylaerts MF, Hendrickx HF, Goergen MJ, De Broe ME.

Int J Cancer. 1991 Feb 1;47(3):431-8.

PMID:
1993552

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