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Items: 1 to 50 of 159

1.

Load Adaptation of Lamellipodial Actin Networks.

Mueller J, Szep G, Nemethova M, de Vries I, Lieber AD, Winkler C, Kruse K, Small JV, Schmeiser C, Keren K, Hauschild R, Sixt M.

Cell. 2017 Sep 21;171(1):188-200.e16. doi: 10.1016/j.cell.2017.07.051. Epub 2017 Aug 31.

PMID:
28867286
2.

Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes.

Leithner A, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J, de Gorter DJ, Schur F, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai FP, Moser M, Kerjaschki D, Rottner K, Small JV, Stradal TE, Sixt M.

Nat Cell Biol. 2016 Nov;18(11):1253-1259. doi: 10.1038/ncb3426. Epub 2016 Oct 24.

PMID:
27775702
3.

KCNJ15/Kir4.2 couples with polyamines to sense weak extracellular electric fields in galvanotaxis.

Nakajima K, Zhu K, Sun YH, Hegyi B, Zeng Q, Murphy CJ, Small JV, Chen-Izu Y, Izumiya Y, Penninger JM, Zhao M.

Nat Commun. 2015 Oct 9;6:8532. doi: 10.1038/ncomms9532.

4.

Pushing with actin: from cells to pathogens.

Small JV.

Biochem Soc Trans. 2015 Feb;43(1):84-91. doi: 10.1042/BST20140184.

PMID:
25619250
5.

MTSS1 is a metastasis driver in a subset of human melanomas.

Mertz KD, Pathria G, Wagner C, Saarikangas J, Sboner A, Romanov J, Gschaider M, Lenz F, Neumann F, Schreiner W, Nemethova M, Glassmann A, Lappalainen P, Stingl G, Small JV, Fink D, Chin L, Wagner SN.

Nat Commun. 2014 Mar 17;5:3465. doi: 10.1038/ncomms4465.

PMID:
24632752
6.

Electron tomography and simulation of baculovirus actin comet tails support a tethered filament model of pathogen propulsion.

Mueller J, Pfanzelter J, Winkler C, Narita A, Le Clainche C, Nemethova M, Carlier MF, Maeda Y, Welch MD, Ohkawa T, Schmeiser C, Resch GP, Small JV.

PLoS Biol. 2014 Jan;12(1):e1001765. doi: 10.1371/journal.pbio.1001765. Epub 2014 Jan 14.

7.

Spectrally coded optical nanosectioning (SpecON) with biocompatible metal-dielectric-coated substrates.

Elsayad K, Urich A, Tan PS, Nemethova M, Small JV, Unterrainer K, Heinze KG.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20069-74. doi: 10.1073/pnas.1307222110. Epub 2013 Nov 25.

8.

Inhibitory signalling to the Arp2/3 complex steers cell migration.

Dang I, Gorelik R, Sousa-Blin C, Derivery E, Guérin C, Linkner J, Nemethova M, Dumortier JG, Giger FA, Chipysheva TA, Ermilova VD, Vacher S, Campanacci V, Herrada I, Planson AG, Fetics S, Henriot V, David V, Oguievetskaia K, Lakisic G, Pierre F, Steffen A, Boyreau A, Peyriéras N, Rottner K, Zinn-Justin S, Cherfils J, Bièche I, Alexandrova AY, David NB, Small JV, Faix J, Blanchoin L, Gautreau A.

Nature. 2013 Nov 14;503(7475):281-4. doi: 10.1038/nature12611. Epub 2013 Oct 16.

PMID:
24132237
9.

Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin.

Koestler SA, Steffen A, Nemethova M, Winterhoff M, Luo N, Holleboom JM, Krupp J, Jacob S, Vinzenz M, Schur F, Schlüter K, Gunning PW, Winkler C, Schmeiser C, Faix J, Stradal TE, Small JV, Rottner K.

Mol Biol Cell. 2013 Sep;24(18):2861-75. doi: 10.1091/mbc.E12-12-0857. Epub 2013 Jul 24.

10.

ADF/cofilin-mediated actin retrograde flow directs neurite formation in the developing brain.

Flynn KC, Hellal F, Neukirchen D, Jacob S, Tahirovic S, Dupraz S, Stern S, Garvalov BK, Gurniak C, Shaw AE, Meyn L, Wedlich-Söldner R, Bamburg JR, Small JV, Witke W, Bradke F.

Neuron. 2012 Dec 20;76(6):1091-107. doi: 10.1016/j.neuron.2012.09.038.

11.

Reconstructing the orientation distribution of actin filaments in the lamellipodium of migrating keratocytes from electron microscopy tomography data.

Weichsel J, Urban E, Small JV, Schwarz US.

Cytometry A. 2012 Jun;81(6):496-507. doi: 10.1002/cyto.a.22050. Epub 2012 Apr 12.

12.

Direct determination of actin polarity in the cell.

Narita A, Mueller J, Urban E, Vinzenz M, Small JV, Maéda Y.

J Mol Biol. 2012 Jun 22;419(5):359-68. doi: 10.1016/j.jmb.2012.03.015. Epub 2012 Mar 26.

13.

Actin branching in the initiation and maintenance of lamellipodia.

Vinzenz M, Nemethova M, Schur F, Mueller J, Narita A, Urban E, Winkler C, Schmeiser C, Koestler SA, Rottner K, Resch GP, Maeda Y, Small JV.

J Cell Sci. 2012 Jun 1;125(Pt 11):2775-85. doi: 10.1242/jcs.107623. Epub 2012 Mar 19.

14.

Actin filament tracking in electron tomograms of negatively stained lamellipodia using the localized radon transform.

Winkler C, Vinzenz M, Small JV, Schmeiser C.

J Struct Biol. 2012 Apr;178(1):19-28. doi: 10.1016/j.jsb.2012.02.011. Epub 2012 Mar 1.

PMID:
22387240
15.

Cofilin cooperates with fascin to disassemble filopodial actin filaments.

Breitsprecher D, Koestler SA, Chizhov I, Nemethova M, Mueller J, Goode BL, Small JV, Rottner K, Faix J.

J Cell Sci. 2011 Oct 1;124(Pt 19):3305-18. doi: 10.1242/jcs.086934.

16.

Microtubules as platforms for assaying actin polymerization in vivo.

Oelkers JM, Vinzenz M, Nemethova M, Jacob S, Lai FP, Block J, Szczodrak M, Kerkhoff E, Backert S, Schlüter K, Stradal TE, Small JV, Koestler SA, Rottner K.

PLoS One. 2011;6(5):e19931. doi: 10.1371/journal.pone.0019931. Epub 2011 May 16.

17.

Molecular mechanism of Ena/VASP-mediated actin-filament elongation.

Breitsprecher D, Kiesewetter AK, Linkner J, Vinzenz M, Stradal TE, Small JV, Curth U, Dickinson RB, Faix J.

EMBO J. 2011 Feb 2;30(3):456-67. doi: 10.1038/emboj.2010.348. Epub 2011 Jan 7.

18.

Dicing with dogma: de-branching the lamellipodium.

Small JV.

Trends Cell Biol. 2010 Nov;20(11):628-33. doi: 10.1016/j.tcb.2010.08.006.

19.

Electron tomography reveals unbranched networks of actin filaments in lamellipodia.

Urban E, Jacob S, Nemethova M, Resch GP, Small JV.

Nat Cell Biol. 2010 May;12(5):429-35. doi: 10.1038/ncb2044. Epub 2010 Apr 25.

PMID:
20418872
20.

Shifting views on the leading role of the lamellipodium in cell migration: speckle tracking revisited.

Vallotton P, Small JV.

J Cell Sci. 2009 Jun 15;122(Pt 12):1955-8. doi: 10.1242/jcs.042036. Review. No abstract available.

21.

Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.

Lai FP, Szczodrak M, Oelkers JM, Ladwein M, Acconcia F, Benesch S, Auinger S, Faix J, Small JV, Polo S, Stradal TE, Rottner K.

Mol Biol Cell. 2009 Jul;20(14):3209-23. doi: 10.1091/mbc.E08-12-1180. Epub 2009 May 20.

22.

Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization.

Colombelli J, Besser A, Kress H, Reynaud EG, Girard P, Caussinus E, Haselmann U, Small JV, Schwarz US, Stelzer EH.

J Cell Sci. 2009 May 15;122(Pt 10):1665-79. doi: 10.1242/jcs.042986. Epub 2009 Apr 28. Erratum in: J Cell Sci. 2009 Jun 1;122(Pt 11):1928.

23.

F- and G-actin concentrations in lamellipodia of moving cells.

Koestler SA, Rottner K, Lai F, Block J, Vinzenz M, Small JV.

PLoS One. 2009;4(3):e4810. doi: 10.1371/journal.pone.0004810. Epub 2009 Mar 11.

24.

Modeling of the actin-cytoskeleton in symmetric lamellipodial fragments.

Oelz D, Schmeiser C, Small JV.

Cell Adh Migr. 2008 Apr-May;2(2):117-26. Review.

25.

Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation.

Breitsprecher D, Kiesewetter AK, Linkner J, Urbanke C, Resch GP, Small JV, Faix J.

EMBO J. 2008 Nov 19;27(22):2943-54. doi: 10.1038/emboj.2008.211. Epub 2008 Oct 16.

26.

Filopodia formation induced by active mDia2/Drf3.

Block J, Stradal TE, Hänisch J, Geffers R, Köstler SA, Urban E, Small JV, Rottner K, Faix J.

J Microsc. 2008 Sep;231(3):506-17. doi: 10.1111/j.1365-2818.2008.02063.x.

27.

Unravelling the structure of the lamellipodium.

Small JV, Auinger S, Nemethova M, Koestler S, Goldie KN, Hoenger A, Resch GP.

J Microsc. 2008 Sep;231(3):479-85. doi: 10.1111/j.1365-2818.2008.02060.x. Review.

28.

Live imaging of glioblastoma cells in brain tissue shows requirement of actin bundles for migration.

Caspani EM, Echevarria D, Rottner K, Small JV.

Neuron Glia Biol. 2006 May;2(2):105-14. doi: 10.1017/S1740925X06000111.

PMID:
18634584
29.

Correlated light and electron microscopy of the cytoskeleton.

Auinger S, Small JV.

Methods Cell Biol. 2008;88:257-72. doi: 10.1016/S0091-679X(08)00414-7. Review.

PMID:
18617038
30.

Role of desmin in active force transmission and maintenance of structure during growth of urinary bladder.

Scott RS, Li Z, Paulin D, Uvelius B, Small JV, Arner A.

Am J Physiol Cell Physiol. 2008 Aug;295(2):C324-31. doi: 10.1152/ajpcell.90622.2007. Epub 2008 Jun 18.

31.

Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella.

Nemethova M, Auinger S, Small JV.

J Cell Biol. 2008 Mar 24;180(6):1233-44. doi: 10.1083/jcb.200709134.

32.

Arp2/3 complex interactions and actin network turnover in lamellipodia.

Lai FP, Szczodrak M, Block J, Faix J, Breitsprecher D, Mannherz HG, Stradal TE, Dunn GA, Small JV, Rottner K.

EMBO J. 2008 Apr 9;27(7):982-92. doi: 10.1038/emboj.2008.34. Epub 2008 Feb 28.

33.

Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front.

Koestler SA, Auinger S, Vinzenz M, Rottner K, Small JV.

Nat Cell Biol. 2008 Mar;10(3):306-13. doi: 10.1038/ncb1692. Epub 2008 Feb 17.

PMID:
18278037
34.

Facing up to Mena: Tes(ting) times for EVH1 domains.

Small JV.

Nat Cell Biol. 2008 Feb;10(2):118-20. doi: 10.1038/ncb0208-118. No abstract available.

PMID:
18246036
35.

Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites.

Efimov A, Schiefermeier N, Grigoriev I, Ohi R, Brown MC, Turner CE, Small JV, Kaverina I.

J Cell Sci. 2008 Jan 15;121(Pt 2):196-204. doi: 10.1242/jcs.012666. Erratum in: J Cell Sci. 2008 Feb 1;121(Pt 3):405. Ohi, Ryoma [added].

36.

PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins.

Jenzora A, Behrendt B, Small JV, Wehland J, Stradal TE.

FEBS Lett. 2006 May 22;580(12):455-63.

PMID:
16783873
37.

Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes.

Steffen A, Faix J, Resch GP, Linkner J, Wehland J, Small JV, Rottner K, Stradal TE.

Mol Biol Cell. 2006 Jun;17(6):2581-91. Epub 2006 Apr 5.

38.

E-cadherin endocytosis regulates the activity of Rap1: a traffic light GTPase at the crossroads between cadherin and integrin function.

Balzac F, Avolio M, Degani S, Kaverina I, Torti M, Silengo L, Small JV, Retta SF.

J Cell Sci. 2005 Oct 15;118(Pt 20):4765-83.

39.

The comings and goings of actin: coupling protrusion and retraction in cell motility.

Small JV, Resch GP.

Curr Opin Cell Biol. 2005 Oct;17(5):517-23. Review.

PMID:
16099152
40.

The last but not the least: the origin and significance of trailing adhesions in fibroblastic cells.

Rid R, Schiefermeier N, Grigoriev I, Small JV, Kaverina I.

Cell Motil Cytoskeleton. 2005 Jul;61(3):161-71.

PMID:
15909298
41.

Raf-1 regulates Rho signaling and cell migration.

Ehrenreiter K, Piazzolla D, Velamoor V, Sobczak I, Small JV, Takeda J, Leung T, Baccarini M.

J Cell Biol. 2005 Mar 14;168(6):955-64. Epub 2005 Mar 7.

42.

PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins.

Jenzora A, Behrendt B, Small JV, Wehland J, Stradal TE.

FEBS Lett. 2005 Jan 17;579(2):455-63.

43.

Biomedical research publication system.

Wang YL, Burridge K, Dembo M, Gabbiani G, Hanks SK, Hosoya H, Janmey P, Karlsson R, Lindberg U, Mabuchi I, Otey C, Rottner K, Small JV, Wang CL, Zigmond S.

Science. 2004 Mar 26;303(5666):1974-6. No abstract available.

PMID:
15044785
44.

Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport.

Hoogenraad CC, Wulf P, Schiefermeier N, Stepanova T, Galjart N, Small JV, Grosveld F, de Zeeuw CI, Akhmanova A.

EMBO J. 2003 Nov 17;22(22):6004-15.

45.

SWAP-70 identifies a transitional subset of actin filaments in motile cells.

Hilpelä P, Oberbanscheidt P, Hahne P, Hund M, Kalhammer G, Small JV, Bähler M.

Mol Biol Cell. 2003 Aug;14(8):3242-53. Epub 2003 Apr 17.

46.

Nanometer targeting of microtubules to focal adhesions.

Krylyshkina O, Anderson KI, Kaverina I, Upmann I, Manstein DJ, Small JV, Toomre DK.

J Cell Biol. 2003 Jun 9;161(5):853-9. Epub 2003 Jun 2.

47.

IRSp53 is colocalised with WAVE2 at the tips of protruding lamellipodia and filopodia independently of Mena.

Nakagawa H, Miki H, Nozumi M, Takenawa T, Miyamoto S, Wehland J, Small JV.

J Cell Sci. 2003 Jun 15;116(Pt 12):2577-83. Epub 2003 May 6.

48.

Microtubules meet substrate adhesions to arrange cell polarity.

Small JV, Kaverina I.

Curr Opin Cell Biol. 2003 Feb;15(1):40-7. Review.

PMID:
12517702
49.

How do microtubules guide migrating cells?

Small JV, Geiger B, Kaverina I, Bershadsky A.

Nat Rev Mol Cell Biol. 2002 Dec;3(12):957-64. doi: 10.1038/nrm971. Review.

PMID:
12461561
50.

Pure F-actin networks are distorted and branched by steps in the critical-point drying method.

Resch GP, Goldie KN, Hoenger A, Small JV.

J Struct Biol. 2002 Mar;137(3):305-12.

PMID:
12096898

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