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Items: 1 to 50 of 329


Health-Promoting Strategies for the Aging Brain.

Chen ST, Volle D, Jalil J, Wu P, Small GW.

Am J Geriatr Psychiatry. 2019 Mar;27(3):213-236. doi: 10.1016/j.jagp.2018.12.016. Epub 2018 Dec 18. Review.


Nocturnal Hypoglycemic Alarm Based on Near-Infrared Spectroscopy: In Vivo Studies with a Rat Animal Model.

Karunathilaka SR, Arnold MA, Small GW.

Anal Chem. 2019 Feb 5;91(3):1855-1862. doi: 10.1021/acs.analchem.8b03437. Epub 2019 Jan 11.


Background correction method for improving the automated detection of radioisotopes from airborne gamma-ray surveys.

Dess BW, Kroutil RT, Small GW.

J Environ Radioact. 2019 Mar;198:104-116. doi: 10.1016/j.jenvrad.2018.12.022. Epub 2018 Dec 29.


Subregional Hippocampal Thickness Abnormalities in Older Adults with a History of Heavy Cannabis Use.

Burggren AC, Siddarth P, Mahmood Z, London ED, Harrison TM, Merrill DA, Small GW, Bookheimer SY.

Cannabis Cannabinoid Res. 2018 Dec 10;3(1):242-251. doi: 10.1089/can.2018.0035. eCollection 2018.


Longer TOMM40 poly-T variants associated with higher FDDNP-PET medial temporal tau and amyloid binding.

Siddarth P, Burggren AC, Merrill DA, Ercoli LM, Mahmood Z, Barrio JR, Small GW.

PLoS One. 2018 Dec 5;13(12):e0208358. doi: 10.1371/journal.pone.0208358. eCollection 2018.


A cross-species approach to disorders affecting brain and behaviour.

Devinsky O, Boesch JM, Cerda-Gonzalez S, Coffey B, Davis K, Friedman D, Hainline B, Houpt K, Lieberman D, Perry P, Prüss H, Samuels MA, Small GW, Volk H, Summerfield A, Vite C, Wisniewski T, Natterson-Horowitz B.

Nat Rev Neurol. 2018 Nov;14(11):677-686. doi: 10.1038/s41582-018-0074-z. Review.


Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining.

Pryor JM, Conlin MP, Carvajal-Garcia J, Luedeman ME, Luthman AJ, Small GW, Ramsden DA.

Science. 2018 Sep 14;361(6407):1126-1129. doi: 10.1126/science.aat2477.


FDDNP-PET Tau Brain Protein Binding Patterns in Military Personnel with Suspected Chronic Traumatic Encephalopathy1.

Chen ST, Siddarth P, Merrill DA, Martinez J, Emerson ND, Liu J, Wong KP, Satyamurthy N, Giza CC, Huang SC, Fitzsimmons RP, Bailes J, Omalu B, Barrio JR, Small GW.

J Alzheimers Dis. 2018;65(1):79-88. doi: 10.3233/JAD-171152.


The Value of In Vitro Binding as Predictor of In Vivo Results: A Case for [18F]FDDNP PET.

Cole GB, Satyamurthy N, Liu J, Wong KP, Small GW, Huang SC, Košmrlj J, Barrio JR, Petrič A.

Mol Imaging Biol. 2019 Feb;21(1):25-34. doi: 10.1007/s11307-018-1210-2.


Response to Letter About Memory and Brain Effects of Curcumin.

Siddarth P, Barrio JR, Small GW.

Am J Geriatr Psychiatry. 2018 Jun;26(6):716-717. doi: 10.1016/j.jagp.2018.03.014. Epub 2018 Mar 29. No abstract available.


Sedentary behavior associated with reduced medial temporal lobe thickness in middle-aged and older adults.

Siddarth P, Burggren AC, Eyre HA, Small GW, Merrill DA.

PLoS One. 2018 Apr 12;13(4):e0195549. doi: 10.1371/journal.pone.0195549. eCollection 2018.


Automated detection of radioisotopes from an aircraft platform by pattern recognition analysis of gamma-ray spectra.

Dess BW, Cardarelli J 2nd, Thomas MJ, Stapleton J, Kroutil RT, Miller D, Curry T, Small GW.

J Environ Radioact. 2018 Dec;192:654-666. doi: 10.1016/j.jenvrad.2018.02.012. Epub 2018 Mar 8.


Simultaneous Aerobic Exercise and Memory Training Program in Older Adults with Subjective Memory Impairments.

McEwen SC, Siddarth P, Abedelsater B, Kim Y, Mui W, Wu P, Emerson ND, Lee J, Greenberg S, Shelton T, Kaiser S, Small GW, Merrill DA.

J Alzheimers Dis. 2018;62(2):795-806. doi: 10.3233/JAD-170846.


Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial.

Small GW, Siddarth P, Li Z, Miller KJ, Ercoli L, Emerson ND, Martinez J, Wong KP, Liu J, Merrill DA, Chen ST, Henning SM, Satyamurthy N, Huang SC, Heber D, Barrio JR.

Am J Geriatr Psychiatry. 2018 Mar;26(3):266-277. doi: 10.1016/j.jagp.2017.10.010. Epub 2017 Oct 27.


Gene expression and linkage analysis implicate CBLB as a mediator of rituximab resistance.

Jack J, Small GW, Brown CC, Havener TM, McLeod HL, Motsinger-Reif AA, Richards KL.

Pharmacogenomics J. 2018 May 22;18(3):467-473. doi: 10.1038/tpj.2017.41. Epub 2017 Dec 5.


Postmortem Autopsy-Confirmation of Antemortem [F-18]FDDNP-PET Scans in a Football Player With Chronic Traumatic Encephalopathy.

Omalu B, Small GW, Bailes J, Ercoli LM, Merrill DA, Wong KP, Huang SC, Satyamurthy N, Hammers JL, Lee J, Fitzsimmons RP, Barrio JR.

Neurosurgery. 2018 Feb 1;82(2):237-246. doi: 10.1093/neuros/nyx536.


In Vivo Brain Plaque and Tangle Burden Mediates the Association Between Diastolic Blood Pressure and Cognitive Functioning in Nondemented Adults.

Roussotte FF, Siddarth P, Merrill DA, Narr KL, Ercoli LM, Martinez J, Emerson ND, Barrio JR, Small GW.

Am J Geriatr Psychiatry. 2018 Jan;26(1):13-22. doi: 10.1016/j.jagp.2017.09.001. Epub 2017 Sep 15.


DNA Ligase IV Guides End-Processing Choice during Nonhomologous End Joining.

Conlin MP, Reid DA, Small GW, Chang HH, Watanabe G, Lieber MR, Ramsden DA, Rothenberg E.

Cell Rep. 2017 Sep 19;20(12):2810-2819. doi: 10.1016/j.celrep.2017.08.091.


Nocturnal hypoglycemic alarm based on near-infrared spectroscopy: In vitro simulation studies.

Karunathilaka SR, Small GW.

Anal Chim Acta. 2017 Sep 22;987:81-90. doi: 10.1016/j.aca.2017.08.035. Epub 2017 Aug 28.


The C677T variant in MTHFR modulates associations between brain integrity, mood, and cognitive functioning in old age.

Roussotte FF, Hua X, Narr KL, Small GW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Apr;2(3):280-288. doi: 10.1016/j.bpsc.2016.09.005.


Hippocampal thinning linked to longer TOMM40 poly-T variant lengths in the absence of the APOE ε4 variant.

Burggren AC, Mahmood Z, Harrison TM, Siddarth P, Miller KJ, Small GW, Merrill DA, Bookheimer SY.

Alzheimers Dement. 2017 Jul;13(7):739-748. doi: 10.1016/j.jalz.2016.12.009. Epub 2017 Feb 7.


Neural correlates of apathy in late-life depression: a pilot [18 F]FDDNP positron emission tomography study.

Eyre HA, Siddarth P, van Dyk K, St Cyr N, Baune BT, Barrio JR, Small GW, Lavretsky H.

Psychogeriatrics. 2017 May;17(3):186-193. doi: 10.1111/psyg.12213. Epub 2017 Jan 28.


Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP.

Doran E, Keator D, Head E, Phelan MJ, Kim R, Totoiu M, Barrio JR, Small GW, Potkin SG, Lott IT.

J Alzheimers Dis. 2017;56(2):459-470. doi: 10.3233/JAD-160836.


Detection and Prevention of Cognitive Decline.

Small GW.

Am J Geriatr Psychiatry. 2016 Dec;24(12):1142-1150. doi: 10.1016/j.jagp.2016.08.013. Epub 2016 Aug 25. Review.


Progressive Focal Gray Matter Volume Loss in a Former High School Football Player: A Possible Magnetic Resonance Imaging Volumetric Signature for Chronic Traumatic Encephalopathy.

Raji CA, Merrill DA, Barrio JR, Omalu B, Small GW.

Am J Geriatr Psychiatry. 2016 Oct;24(10):784-90. doi: 10.1016/j.jagp.2016.07.018. Epub 2016 Jul 28.


An Alzheimer's Disease Genetic Risk Score Predicts Longitudinal Thinning of Hippocampal Complex Subregions in Healthy Older Adults.

Harrison TM, Mahmood Z, Lau EP, Karacozoff AM, Burggren AC, Small GW, Bookheimer SY.

eNeuro. 2016 Jul 15;3(3). pii: ENEURO.0098-16.2016. doi: 10.1523/ENEURO.0098-16.2016. eCollection 2016 May-Jun.


Modifiable Risk Factors and Brain Positron Emission Tomography Measures of Amyloid and Tau in Nondemented Adults with Memory Complaints.

Merrill DA, Siddarth P, Raji CA, Emerson ND, Rueda F, Ercoli LM, Miller KJ, Lavretsky H, Harris LM, Burggren AC, Bookheimer SY, Barrio JR, Small GW.

Am J Geriatr Psychiatry. 2016 Sep;24(9):729-37. doi: 10.1016/j.jagp.2016.05.007. Epub 2016 May 13.


The C677T variant in MTHFR modulates associations between blood-based and cerebrospinal fluid biomarkers of neurodegeneration.

Roussotte FF, Narr KL, Small GW, Thompson PM; Alzheimer’s Disease Neuroimaging Initiative.

Neuroreport. 2016 Aug 17;27(12):948-51. doi: 10.1097/WNR.0000000000000636.



Lavretsky H, Small GW.

J Clin Psychiatry. 2016 Jan;77(1):116. doi: 10.4088/JCP.15f10522. No abstract available.


Current and Future Treatments for Alzheimer Disease.

Small GW, Greenfield S.

Am J Geriatr Psychiatry. 2015 Nov;23(11):1101-5. doi: 10.1016/j.jagp.2015.08.006. Epub 2015 Sep 9. No abstract available.


Altered memory-related functional connectivity of the anterior and posterior hippocampus in older adults at increased genetic risk for Alzheimer's disease.

Harrison TM, Burggren AC, Small GW, Bookheimer SY.

Hum Brain Mapp. 2016 Jan;37(1):366-80. doi: 10.1002/hbm.23036. Epub 2015 Oct 27.


Neuropsychological tests for predicting cognitive decline in older adults.

Baerresen KM, Miller KJ, Hanson ER, Miller JS, Dye RV, Hartman RE, Vermeersch D, Small GW.

Neurodegener Dis Manag. 2015;5(3):191-201. doi: 10.2217/nmt.15.7.


Design and characterization of protein films for modeling near-infrared spectra of human tissue.

Karunathilaka SR, Small GW.

Analyst. 2015 Jun 21;140(12):3981-8. doi: 10.1039/c5an00258c. Epub 2015 Apr 20.


In vivo characterization of chronic traumatic encephalopathy using [F-18]FDDNP PET brain imaging.

Barrio JR, Small GW, Wong KP, Huang SC, Liu J, Merrill DA, Giza CC, Fitzsimmons RP, Omalu B, Bailes J, Kepe V.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E2039-47. doi: 10.1073/pnas.1409952112. Epub 2015 Apr 6. Erratum in: Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):E2981.


Calibration diagnostic and updating strategy based on quantitative modeling of near-infrared spectral residuals.

Yu H, Small GW.

Analyst. 2015 Feb 7;140(3):786-96. doi: 10.1039/c4an01849d.


Automated movement correction for dynamic PET/CT images: evaluation with phantom and patient data.

Ye H, Wong KP, Wardak M, Dahlbom M, Kepe V, Barrio JR, Nelson LD, Small GW, Huang SC.

PLoS One. 2014 Aug 11;9(8):e103745. doi: 10.1371/journal.pone.0103745. eCollection 2014.


Modifiable risk factors for Alzheimer disease and subjective memory impairment across age groups.

Chen ST, Siddarth P, Ercoli LM, Merrill DA, Torres-Gil F, Small GW.

PLoS One. 2014 Jun 4;9(6):e98630. doi: 10.1371/journal.pone.0098630. eCollection 2014.


Life extension factor klotho enhances cognition.

Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, Sturm VE, Kim D, Klein E, Yu GQ, Ho K, Eilertson KE, Yu L, Kuro-o M, De Jager PL, Coppola G, Small GW, Bennett DA, Kramer JH, Abraham CR, Miller BL, Mucke L.

Cell Rep. 2014 May 22;7(4):1065-76. doi: 10.1016/j.celrep.2014.03.076. Epub 2014 May 10.


Treating dementia and agitation.

Small GW.

JAMA. 2014 Feb 19;311(7):677-8. doi: 10.1001/jama.2014.94. No abstract available.


KIAA1462, a coronary artery disease associated gene, is a candidate gene for late onset Alzheimer disease in APOE carriers.

Murdock DG, Bradford Y, Schnetz-Boutaud N, Mayo P, Allen MJ, D'Aoust LN, Liang X, Mitchell SL, Zuchner S, Small GW, Gilbert JR, Pericak-Vance MA, Haines JL.

PLoS One. 2013 Dec 12;8(12):e82194. doi: 10.1371/journal.pone.0082194. eCollection 2013.


VH1-44 gene usage defines a subset of canine B-cell lymphomas associated with better patient survival.

Chen HW, Small GW, Motsinger-Reif A, Suter SE, Richards KL.

Vet Immunol Immunopathol. 2014 Feb 15;157(3-4):125-30. doi: 10.1016/j.vetimm.2013.10.020. Epub 2013 Nov 21.


APOE associated hemispheric asymmetry of entorhinal cortical thickness in aging and Alzheimer's disease.

Donix M, Burggren AC, Scharf M, Marschner K, Suthana NA, Siddarth P, Krupa AK, Jones M, Martin-Harris L, Ercoli LM, Miller KJ, Werner A, von Kummer R, Sauer C, Small GW, Holthoff VA, Bookheimer SY.

Psychiatry Res. 2013 Dec 30;214(3):212-20. doi: 10.1016/j.pscychresns.2013.09.006. Epub 2013 Sep 27.


Expression of asparagine synthetase predicts in vitro response to L-asparaginase in canine lymphoid cell lines.

Smallwood TL, Small GW, Suter SE, Richards KL.

Leuk Lymphoma. 2014 Jun;55(6):1357-65. doi: 10.3109/10428194.2013.842980. Epub 2013 Nov 14.


Pomegranate juice augments memory and FMRI activity in middle-aged and older adults with mild memory complaints.

Bookheimer SY, Renner BA, Ekstrom A, Li Z, Henning SM, Brown JA, Jones M, Moody T, Small GW.

Evid Based Complement Alternat Med. 2013;2013:946298. doi: 10.1155/2013/946298. Epub 2013 Jul 22.


Gene profiling of canine B-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human DLBCL.

Richards KL, Motsinger-Reif AA, Chen HW, Fedoriw Y, Fan C, Nielsen DM, Small GW, Thomas R, Smith C, Dave SS, Perou CM, Breen M, Borst LB, Suter SE.

Cancer Res. 2013 Aug 15;73(16):5029-39. doi: 10.1158/0008-5472.CAN-12-3546. Epub 2013 Jun 19.


Analysis of innate and acquired resistance to anti-CD20 antibodies in malignant and nonmalignant B cells.

Small GW, McLeod HL, Richards KL.

PeerJ. 2013 Feb 12;1:e31. doi: 10.7717/peerj.31. Print 2013.


PET imaging of neuropathology in tauopathies: progressive supranuclear palsy.

Kepe V, Bordelon Y, Boxer A, Huang SC, Liu J, Thiede FC, Mazziotta JC, Mendez MF, Donoghue N, Small GW, Barrio JR.

J Alzheimers Dis. 2013;36(1):145-53. doi: 10.3233/JAD-130032.


Postmortem 3-D brain hemisphere cortical tau and amyloid-β pathology mapping and quantification as a validation method of neuropathology imaging.

Smid LM, Kepe V, Vinters HV, Bresjanac M, Toyokuni T, Satyamurthy N, Wong KP, Huang SC, Silverman DH, Miller K, Small GW, Barrio JR.

J Alzheimers Dis. 2013;36(2):261-74. doi: 10.3233/JAD-122434.


Psychological well-being and regional brain amyloid and tau in mild cognitive impairment.

Chen ST, Siddarth P, Saito NY, Rueda F, Haight T, Ercoli LM, Miller KJ, Lavretsky H, Barrio JR, Bookheimer SY, Small GW, Merrill DA.

Am J Geriatr Psychiatry. 2014 Apr;22(4):362-9. doi: 10.1016/j.jagp.2012.09.002. Epub 2013 Mar 26.

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