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Items: 23


Deficiency of the tumor promoter gene wip1 induces insulin resistance.

Armata HL, Chamberland S, Watts L, Ko HJ, Lee Y, Jung DY, Kim JK, Sluss HK.

Mol Endocrinol. 2015 Jan;29(1):28-39. doi: 10.1210/me.2014-1136.


Glucose Tolerance in Mice is Linked to the Dose of the p53 Transactivation Domain.

Franck D, Tracy L, Armata HL, Delaney CL, Jung DY, Ko HJ, Ong H, Kim JK, Scrable H, Sluss HK.

Endocr Res. 2013 Aug;38(3):139-150. doi: 10.3109/07435800.2012.735735. Epub 2012 Oct 26.


Loss of p53 Ser18 and Atm results in embryonic lethality without cooperation in tumorigenesis.

Armata HL, Shroff P, Garlick DE, Penta K, Tapper AR, Sluss HK.

PLoS One. 2011;6(9):e24813. doi: 10.1371/journal.pone.0024813. Epub 2011 Sep 27.


Mice defective in p53 nuclear localization signal 1 exhibit exencephaly.

Regeling A, Armata HL, Gallant J, Jones SN, Sluss HK.

Transgenic Res. 2011 Aug;20(4):899-912. doi: 10.1007/s11248-010-9468-4. Epub 2010 Dec 3.


Requirement of the ATM/p53 tumor suppressor pathway for glucose homeostasis.

Armata HL, Golebiowski D, Jung DY, Ko HJ, Kim JK, Sluss HK.

Mol Cell Biol. 2010 Dec;30(24):5787-94. doi: 10.1128/MCB.00347-10. Epub 2010 Oct 18.


Role of JNK in a Trp53-dependent mouse model of breast cancer.

Cellurale C, Weston CR, Reilly J, Garlick DS, Jerry DJ, Sluss HK, Davis RJ.

PLoS One. 2010 Aug 30;5(8):e12469. doi: 10.1371/journal.pone.0012469.


p53 represses class switch recombination to IgG2a through its antioxidant function.

Guikema JE, Schrader CE, Brodsky MH, Linehan EK, Richards A, El Falaky N, Li DH, Sluss HK, Szomolanyi-Tsuda E, Stavnezer J.

J Immunol. 2010 Jun 1;184(11):6177-87. doi: 10.4049/jimmunol.0904085. Epub 2010 May 5. Erratum in: J Immunol. 2011 Nov 1;187(9):4920.


Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.

Sluss HK, Gannon H, Coles AH, Shen Q, Eischen CM, Jones SN.

Mol Cancer Res. 2010 Feb;8(2):216-22. doi: 10.1158/1541-7786.MCR-09-0324. Epub 2010 Feb 9.


The ataxia telangiectasia-mutated target site Ser18 is required for p53-mediated tumor suppression.

Armata HL, Garlick DS, Sluss HK.

Cancer Res. 2007 Dec 15;67(24):11696-703.


Suppression of p53-dependent senescence by the JNK signal transduction pathway.

Das M, Jiang F, Sluss HK, Zhang C, Shokat KM, Flavell RA, Davis RJ.

Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15759-64. Epub 2007 Sep 24.


Phosphorylation of serine 18 regulates distinct p53 functions in mice.

Sluss HK, Armata H, Gallant J, Jones SN.

Mol Cell Biol. 2004 Feb;24(3):976-84.


Absence of p21 partially rescues Mdm4 loss and uncovers an antiproliferative effect of Mdm4 on cell growth.

Steinman HA, Sluss HK, Sands AT, Pihan G, Jones SN.

Oncogene. 2004 Jan 8;23(1):303-6.


Suppression of Ras-stimulated transformation by the JNK signal transduction pathway.

Kennedy NJ, Sluss HK, Jones SN, Bar-Sagi D, Flavell RA, Davis RJ.

Genes Dev. 2003 Mar 1;17(5):629-37.


Analysing p53 tumour suppressor functions in mice.

Sluss HK, Jones SN.

Expert Opin Ther Targets. 2003 Feb;7(1):89-99. Review.


A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.

Sluss HK, Han Z, Barrett T, Goberdhan DC, Wilson C, Davis RJ, Ip YT.

Genes Dev. 1996 Nov 1;10(21):2745-58. Erratum in: Genes Dev. 1997 Feb 15;11(4):541. Goberdhan, D C [added]; Wilson, C [added].


Selective interaction of JNK protein kinase isoforms with transcription factors.

Gupta S, Barrett T, Whitmarsh AJ, Cavanagh J, Sluss HK, Dérijard B, Davis RJ.

EMBO J. 1996 Jun 3;15(11):2760-70.


p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest.

Ewen ME, Oliver CJ, Sluss HK, Miller SJ, Peeper DS.

Genes Dev. 1995 Jan 15;9(2):204-17.


JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation.

Kallunki T, Su B, Tsigelny I, Sluss HK, Dérijard B, Moore G, Davis R, Karin M.

Genes Dev. 1994 Dec 15;8(24):2996-3007.


Signal transduction by tumor necrosis factor mediated by JNK protein kinases.

Sluss HK, Barrett T, Dérijard B, Davis RJ.

Mol Cell Biol. 1994 Dec;14(12):8376-84.


TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest.

Ewen ME, Sluss HK, Whitehouse LL, Livingston DM.

Cell. 1993 Sep 24;74(6):1009-20.


Functional interactions of the retinoblastoma protein with mammalian D-type cyclins.

Ewen ME, Sluss HK, Sherr CJ, Matsushime H, Kato J, Livingston DM.

Cell. 1993 May 7;73(3):487-97.


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