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Items: 1 to 50 of 99

1.

SUMOylation coordinates BERosome assembly in active DNA demethylation during cell differentiation.

Steinacher R, Barekati Z, Botev P, Kuśnierczyk A, Slupphaug G, Schär P.

EMBO J. 2019 Jan 3;38(1). pii: e99242. doi: 10.15252/embj.201899242. Epub 2018 Dec 6.

PMID:
30523148
2.

Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity.

Souza RWA, Alves CRR, Medeiros A, Rolim N, Silva GJJ, Moreira JBN, Alves MN, Wohlwend M, Gebriel M, Hagen L, Sharma A, Koch LG, Britton SL, Slupphaug G, Wisløff U, Brum PC.

Sci Rep. 2018 Dec 11;8(1):17772. doi: 10.1038/s41598-018-35728-2.

3.

Characterization of the proteome and lipidome profiles of human lung cells after low dose and chronic exposure to multiwalled carbon nanotubes.

Phuyal S, Kasem M, Knittelfelder O, Sharma A, Fonseca DM, Vebraite V, Shaposhnikov S, Slupphaug G, Skaug V, Zienolddiny S.

Nanotoxicology. 2018 Mar;12(2):138-152. doi: 10.1080/17435390.2018.1425500. Epub 2018 Jan 19.

PMID:
29350075
4.

A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair.

Brickner JR, Soll JM, Lombardi PM, Vågbø CB, Mudge MC, Oyeniran C, Rabe R, Jackson J, Sullender ME, Blazosky E, Byrum AK, Zhao Y, Corbett MA, Gécz J, Field M, Vindigni A, Slupphaug G, Wolberger C, Mosammaparast N.

Nature. 2017 Nov 16;551(7680):389-393. doi: 10.1038/nature24484. Epub 2017 Nov 8.

5.

Backbone 1H, 13C and 15N chemical shift assignment of full-length human uracil DNA glycosylase UNG2.

Buchinger E, Wiik SÅ, Kusnierczyk A, Rabe R, Aas PA, Kavli B, Slupphaug G, Aachmann FL.

Biomol NMR Assign. 2018 Apr;12(1):15-22. doi: 10.1007/s12104-017-9772-5. Epub 2017 Sep 6.

PMID:
28879561
6.

No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice.

Rolseth V, Luna L, Olsen AK, Suganthan R, Scheffler K, Neurauter CG, Esbensen Y, Kuśnierczyk A, Hildrestrand GA, Graupner A, Andersen JM, Slupphaug G, Klungland A, Nilsen H, Bjørås M.

Sci Rep. 2017 Jun 29;7(1):4384. doi: 10.1038/s41598-017-04472-4.

7.

Changes in cellular signaling proteins in extracts from A549, H460, and U2OS cells treated with cisplatin or docetaxel.

Petrovic V, Olaisen C, Sharma A, Nepal A, Bugge S, Sundby E, Hoff BH, Slupphaug G, Otterlei M.

Data Brief. 2017 Mar 18;12:18-21. doi: 10.1016/j.dib.2017.03.023. eCollection 2017 Jun.

8.

Novel UCHL1 mutations reveal new insights into ubiquitin processing.

Rydning SL, Backe PH, Sousa MML, Iqbal Z, Øye AM, Sheng Y, Yang M, Lin X, Slupphaug G, Nordenmark TH, Vigeland MD, Bjørås M, Tallaksen CM, Selmer KK.

Hum Mol Genet. 2017 Mar 15;26(6):1217-1218. doi: 10.1093/hmg/ddx072. No abstract available.

PMID:
28334853
9.

On-column trypsinization allows for re-use of matrix in modified multiplexed inhibitor beads assay.

Petrovic V, Olaisen C, Sharma A, Nepal A, Bugge S, Sundby E, Hoff BH, Slupphaug G, Otterlei M.

Anal Biochem. 2017 Apr 15;523:10-16. doi: 10.1016/j.ab.2017.01.027. Epub 2017 Feb 3.

10.

NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture.

Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JDS, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P, Yndestad A, Aukrust P, Bjørås M, Finsen AV.

Cell Rep. 2017 Jan 3;18(1):82-92. doi: 10.1016/j.celrep.2016.12.009.

11.

Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia.

Zatula A, Dikic A, Mulder C, Sharma A, Vågbø CB, Sousa MML, Waage A, Slupphaug G.

Oncotarget. 2017 Mar 21;8(12):19427-19442. doi: 10.18632/oncotarget.14294.

12.

Novel UCHL1 mutations reveal new insights into ubiquitin processing.

Rydning SL, Backe PH, Sousa MML, Iqbal Z, Øye AM, Sheng Y, Yang M, Lin X, Slupphaug G, Nordenmark TH, Vigeland MD, Bjørås M, Tallaksen CM, Selmer KK.

Hum Mol Genet. 2017 Mar 15;26(6):1031-1040. doi: 10.1093/hmg/ddw391. Erratum in: Hum Mol Genet. 2017 Mar 15;26(6):1217-1218.

PMID:
28007905
13.

Pso p27, a SERPINB3/B4-derived protein, is most likely a common autoantigen in chronic inflammatory diseases.

Iversen OJ, Lysvand H, Slupphaug G.

Clin Immunol. 2017 Jan;174:10-17. doi: 10.1016/j.clim.2016.11.006. Epub 2016 Nov 15. Review.

14.

Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA.

Skarpengland T, Dahl TB, Skjelland M, Scheffler K, de Sousa MML, Gregersen I, Kuśnierczyk A, Sharma A, Slupphaug G, Eide L, Segers FM, Skagen KR, Dahl CP, Russell D, Folkersen L, Krohg-Sørensen K, Holm S, Bjørås M, Aukrust P, Halvorsen B.

Free Radic Biol Med. 2016 Aug;97:386-397. doi: 10.1016/j.freeradbiomed.2016.07.001. Epub 2016 Jul 2.

PMID:
27381496
15.

Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.

Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A, Folkersen L, Ueland T, Berge RK, Hansson GK, Biessen EA, Halvorsen B, Bjørås M, Aukrust P.

Sci Rep. 2016 Jun 22;6:28337. doi: 10.1038/srep28337.

16.

Photodynamic treatment with hexyl-aminolevulinate mediates reversible thiol oxidation in core oxidative stress signaling proteins.

Helander L, Sharma A, Krokan HE, Plaetzer K, Krammer B, Tortik N, Gederaas OA, Slupphaug G, Hagen L.

Mol Biosyst. 2016 Mar;12(3):796-805. doi: 10.1039/c5mb00744e.

PMID:
26742548
17.

Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice.

Bjørge MD, Hildrestrand GA, Scheffler K, Suganthan R, Rolseth V, Kuśnierczyk A, Rowe AD, Vågbø CB, Vetlesen S, Eide L, Slupphaug G, Nakabeppu Y, Bredy TW, Klungland A, Bjørås M.

Cell Rep. 2015 Dec 29;13(12):2671-8. doi: 10.1016/j.celrep.2015.12.001. Epub 2015 Dec 17.

18.

Aerobic interval training reduces inducible ventricular arrhythmias in diabetic mice after myocardial infarction.

Rolim N, Skårdal K, Høydal M, Sousa MM, Malmo V, Kaurstad G, Ingul CB, Hansen HE, Alves MN, Thuen M, Haraldseth O, Brum PC, Slupphaug G, Loennechen JP, Stølen T, Wisløff U.

Basic Res Cardiol. 2015;110(4):44. doi: 10.1007/s00395-015-0502-9. Epub 2015 Jun 26.

PMID:
26112154
19.

Psoriasis pathogenesis - Pso p27 constitutes a compact structure forming large aggregates.

Lysvand H, Helland R, Hagen L, Slupphaug G, Iversen OJ.

Biochem Biophys Rep. 2015 Jun 9;2:132-136. doi: 10.1016/j.bbrep.2015.06.001. eCollection 2015 Jul.

20.

Cell cycle regulation of human DNA repair and chromatin remodeling genes.

Mjelle R, Hegre SA, Aas PA, Slupphaug G, Drabløs F, Saetrom P, Krokan HE.

DNA Repair (Amst). 2015 Jun;30:53-67. doi: 10.1016/j.dnarep.2015.03.007. Epub 2015 Mar 28.

21.

Modulation of cell metabolic pathways and oxidative stress signaling contribute to acquired melphalan resistance in multiple myeloma cells.

Zub KA, Sousa MM, Sarno A, Sharma A, Demirovic A, Rao S, Young C, Aas PA, Ericsson I, Sundan A, Jensen ON, Slupphaug G.

PLoS One. 2015 Mar 13;10(3):e0119857. doi: 10.1371/journal.pone.0119857. eCollection 2015.

22.

Protein phosphatase 2A holoenzyme is targeted to peroxisomes by piggybacking and positively affects peroxisomal β-oxidation.

Kataya AR, Heidari B, Hagen L, Kommedal R, Slupphaug G, Lillo C.

Plant Physiol. 2015 Feb;167(2):493-506. doi: 10.1104/pp.114.254409. Epub 2014 Dec 8.

23.

AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.

Pettersen HS, Galashevskaya A, Doseth B, Sousa MM, Sarno A, Visnes T, Aas PA, Liabakk NB, Slupphaug G, Sætrom P, Kavli B, Krokan HE.

DNA Repair (Amst). 2015 Jan;25:60-71. doi: 10.1016/j.dnarep.2014.11.006. Epub 2014 Nov 24.

24.

Off-target responses in the HeLa proteome subsequent to transient plasmid-mediated transfection.

Hagen L, Sharma A, Aas PA, Slupphaug G.

Biochim Biophys Acta. 2015 Jan;1854(1):84-90. doi: 10.1016/j.bbapap.2014.10.016. Epub 2014 Nov 5.

PMID:
25448019
25.

Error-free versus mutagenic processing of genomic uracil--relevance to cancer.

Krokan HE, Sætrom P, Aas PA, Pettersen HS, Kavli B, Slupphaug G.

DNA Repair (Amst). 2014 Jul;19:38-47. doi: 10.1016/j.dnarep.2014.03.028. Epub 2014 Apr 18. Review.

26.

Psoriasis pathogenesis - Pso p27 is generated from SCCA1 with chymase.

Lysvand H, Hagen L, Klubicka L, Slupphaug G, Iversen OJ.

Biochim Biophys Acta. 2014 May;1842(5):734-8. doi: 10.1016/j.bbadis.2014.02.005. Epub 2014 Feb 18.

27.

Atrial myocyte function and Ca2+ handling is associated with inborn aerobic capacity.

Johnsen AB, Rolim NP, Stølen T, Alves M, Sousa MM, Slupphaug G, Britton SL, Koch LG, Smith GL, Wisløff U, Høydal MA.

PLoS One. 2013 Oct 16;8(10):e76568. doi: 10.1371/journal.pone.0076568. eCollection 2013.

28.

A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported.

Galashevskaya A, Sarno A, Vågbø CB, Aas PA, Hagen L, Slupphaug G, Krokan HE.

DNA Repair (Amst). 2013 Sep;12(9):699-706. doi: 10.1016/j.dnarep.2013.05.002. Epub 2013 Jun 3.

29.

An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells.

Sousa MM, Zub KA, Aas PA, Hanssen-Bauer A, Demirovic A, Sarno A, Tian E, Liabakk NB, Slupphaug G.

PLoS One. 2013;8(2):e55493. doi: 10.1371/journal.pone.0055493. Epub 2013 Feb 6.

30.

A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching.

Hu Y, Ericsson I, Torseth K, Methot SP, Sundheim O, Liabakk NB, Slupphaug G, Di Noia JM, Krokan HE, Kavli B.

J Mol Biol. 2013 Jan 23;425(2):424-43. doi: 10.1016/j.jmb.2012.11.026. Epub 2012 Nov 23.

PMID:
23183374
31.

Eating behavior and glucagon-like peptide-1-producing cells in interposed ileum and pancreatic islets in rats subjected to ileal interposition associated with sleeve gastrectomy.

Johannessen H, Kodama Y, Zhao CM, Sousa MM, Slupphaug G, Kulseng B, Chen D.

Obes Surg. 2013 Jan;23(1):39-49. doi: 10.1007/s11695-012-0750-9.

PMID:
22949011
32.

The UNG2 Arg88Cys variant abrogates RPA-mediated recruitment of UNG2 to single-stranded DNA.

Torseth K, Doseth B, Hagen L, Olaisen C, Liabakk NB, Græsmann H, Durandy A, Otterlei M, Krokan HE, Kavli B, Slupphaug G.

DNA Repair (Amst). 2012 Jun 1;11(6):559-69. doi: 10.1016/j.dnarep.2012.03.006. Epub 2012 Apr 20.

PMID:
22521144
33.

Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase.

Roberts VA, Pique ME, Hsu S, Li S, Slupphaug G, Rambo RP, Jamison JW, Liu T, Lee JH, Tainer JA, Ten Eyck LF, Woods VL Jr.

Nucleic Acids Res. 2012 Jul;40(13):6070-81. Epub 2012 Apr 6.

34.

Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil.

Doseth B, Ekre C, Slupphaug G, Krokan HE, Kavli B.

DNA Repair (Amst). 2012 Jun 1;11(6):587-93. doi: 10.1016/j.dnarep.2012.03.003. Epub 2012 Apr 6.

PMID:
22483865
35.

mtSSB may sequester UNG1 at mitochondrial ssDNA and delay uracil processing until the dsDNA conformation is restored.

Wollen Steen K, Doseth B, P Westbye M, Akbari M, Kang D, Falkenberg M, Slupphaug G.

DNA Repair (Amst). 2012 Jan 2;11(1):82-91. doi: 10.1016/j.dnarep.2011.10.026. Epub 2011 Dec 5.

36.
37.

XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage.

Hanssen-Bauer A, Solvang-Garten K, Sundheim O, Peña-Diaz J, Andersen S, Slupphaug G, Krokan HE, Wilson DM 3rd, Akbari M, Otterlei M.

Environ Mol Mutagen. 2011 Oct;52(8):623-35. doi: 10.1002/em.20663. Epub 2011 Jul 22.

38.

UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.

Pettersen HS, Visnes T, Vågbø CB, Svaasand EK, Doseth B, Slupphaug G, Kavli B, Krokan HE.

Nucleic Acids Res. 2011 Oct;39(19):8430-44. doi: 10.1093/nar/gkr563. Epub 2011 Jul 10.

39.

Uracil-DNA glycosylase in base excision repair and adaptive immunity: species differences between man and mouse.

Doseth B, Visnes T, Wallenius A, Ericsson I, Sarno A, Pettersen HS, Flatberg A, Catterall T, Slupphaug G, Krokan HE, Kavli B.

J Biol Chem. 2011 May 13;286(19):16669-80. doi: 10.1074/jbc.M111.230052. Epub 2011 Mar 23.

40.

Photodynamic therapy with hexyl aminolevulinate induces carbonylation, posttranslational modifications and changed expression of proteins in cell survival and cell death pathways.

Baglo Y, Sousa MM, Slupphaug G, Hagen L, Håvåg S, Helander L, Zub KA, Krokan HE, Gederaas OA.

Photochem Photobiol Sci. 2011 Jul;10(7):1137-45. doi: 10.1039/c0pp00369g. Epub 2011 Mar 30.

PMID:
21448498
41.

Uracil DNA N-glycosylase promotes assembly of human centromere protein A.

Zeitlin SG, Chapados BR, Baker NM, Tai C, Slupphaug G, Wang JY.

PLoS One. 2011 Mar 2;6(3):e17151. doi: 10.1371/journal.pone.0017151.

42.

Divergent ß-hairpins determine double-strand versus single-strand substrate recognition of human AlkB-homologues 2 and 3.

Monsen VT, Sundheim O, Aas PA, Westbye MP, Sousa MM, Slupphaug G, Krokan HE.

Nucleic Acids Res. 2010 Oct;38(19):6447-55. doi: 10.1093/nar/gkq518. Epub 2010 Jun 4.

43.

Identification of a novel in vivo virus-targeted phosphorylation site in interferon regulatory factor-3 (IRF3).

Bergstroem B, Johnsen IB, Nguyen TT, Hagen L, Slupphaug G, Thommesen L, Anthonsen MW.

J Biol Chem. 2010 Aug 6;285(32):24904-14. doi: 10.1074/jbc.M109.084822. Epub 2010 May 28.

44.

Identification of a novel, widespread, and functionally important PCNA-binding motif.

Gilljam KM, Feyzi E, Aas PA, Sousa MM, Müller R, Vågbø CB, Catterall TC, Liabakk NB, Slupphaug G, Drabløs F, Krokan HE, Otterlei M.

J Cell Biol. 2009 Sep 7;186(5):645-54. doi: 10.1083/jcb.200903138.

45.

Human immunodeficiency virus type 1 Vpr modulates cellular expression of UNG2 via a negative transcriptional effect.

Langevin C, Maidou-Peindara P, Aas PA, Jacquot G, Otterlei M, Slupphaug G, Benichou S.

J Virol. 2009 Oct;83(19):10256-63. doi: 10.1128/JVI.02654-08. Epub 2009 Jul 22.

46.

Opposite-base dependent excision of 5-formyluracil from DNA by hSMUG1.

Knaevelsrud I, Slupphaug G, Leiros I, Matsuda A, Ruoff P, Bjelland S.

Int J Radiat Biol. 2009 May;85(5):413-20. doi: 10.1080/09553000902818915.

PMID:
19365746
47.

Uracil in DNA and its processing by different DNA glycosylases.

Visnes T, Doseth B, Pettersen HS, Hagen L, Sousa MM, Akbari M, Otterlei M, Kavli B, Slupphaug G, Krokan HE.

Philos Trans R Soc Lond B Biol Sci. 2009 Mar 12;364(1517):563-8. doi: 10.1098/rstb.2008.0186. Review.

48.

AlkB demethylases flip out in different ways.

Sundheim O, Talstad VA, Vågbø CB, Slupphaug G, Krokan HE.

DNA Repair (Amst). 2008 Nov 1;7(11):1916-23. doi: 10.1016/j.dnarep.2008.07.015. Epub 2008 Sep 6. Review.

PMID:
18723127
49.

The rate of base excision repair of uracil is controlled by the initiating glycosylase.

Visnes T, Akbari M, Hagen L, Slupphaug G, Krokan HE.

DNA Repair (Amst). 2008 Nov 1;7(11):1869-81. doi: 10.1016/j.dnarep.2008.07.012. Epub 2008 Sep 4.

PMID:
18721906
50.

Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.

Westbye MP, Feyzi E, Aas PA, Vågbø CB, Talstad VA, Kavli B, Hagen L, Sundheim O, Akbari M, Liabakk NB, Slupphaug G, Otterlei M, Krokan HE.

J Biol Chem. 2008 Sep 5;283(36):25046-56. doi: 10.1074/jbc.M803776200. Epub 2008 Jul 3.

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