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Items: 1 to 50 of 547

1.

Paternal Δ9-Tetrahydrocannabinol Exposure Prior to Mating Elicits Deficits in Cholinergic Synaptic Function in the Offspring.

Slotkin TA, Skavicus S, Levin ED, Seidler FJ.

Toxicol Sci. 2020 Apr 1;174(2):210-217. doi: 10.1093/toxsci/kfaa004.

PMID:
32077955
2.

Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish.

Hawkey AB, Glazer L, Dean C, Wells CN, Odamah KA, Slotkin TA, Seidler FJ, Levin ED.

Neurotoxicol Teratol. 2020 Mar - Apr;78:106853. doi: 10.1016/j.ntt.2019.106853. Epub 2020 Jan 3.

PMID:
31911208
3.

Perinatal diazinon exposure compromises the development of acetylcholine and serotonin systems.

Slotkin TA, Skavicus S, Ko A, Levin ED, Seidler FJ.

Toxicology. 2019 Aug 1;424:152240. doi: 10.1016/j.tox.2019.152240. Epub 2019 Jun 25.

PMID:
31251962
4.

Corrigendum to "The Developmental Neurotoxicity of Tobacco Smoke Can Be Mimicked by a Combination of Nicotine and Benzo[a]pyrene: Effects on Cholinergic and Serotonergic Systems".

Slotkin TA, Skavicus S, Ko A, Levin ED, Seidler FJ.

Toxicol Sci. 2019 Mar 1;168(1):280. doi: 10.1093/toxsci/kfy304. No abstract available.

5.
6.

Critical developmental periods for effects of low-level tobacco smoke exposure on behavioral performance.

Cauley M, Hall BJ, Abreu-Villaça Y, Junaid S, White H, Kiany A, Slotkin TA, Levin ED.

Neurotoxicology. 2018 Sep;68:81-87. doi: 10.1016/j.neuro.2018.07.012. Epub 2018 Jul 20.

7.

Does growth impairment underlie the adverse effects of dexamethasone on development of noradrenergic systems?

Slotkin TA, Ko A, Seidler FJ.

Toxicology. 2018 Sep 1;408:11-21. doi: 10.1016/j.tox.2018.06.008. Epub 2018 Jun 20.

8.

Developmental neurotoxicity resulting from pharmacotherapy of preterm labor, modeled in vitro: Terbutaline and dexamethasone, separately and together.

Slotkin TA, Skavicus S, Seidler FJ.

Toxicology. 2018 May 1;400-401:57-64. doi: 10.1016/j.tox.2018.03.001. Epub 2018 Mar 7.

9.

Brominated and organophosphate flame retardants target different neurodevelopmental stages, characterized with embryonic neural stem cells and neuronotypic PC12 cells.

Slotkin TA, Skavicus S, Stapleton HM, Seidler FJ.

Toxicology. 2017 Sep 1;390:32-42. doi: 10.1016/j.tox.2017.08.009. Epub 2017 Aug 26.

10.

Diazinon and parathion diverge in their effects on development of noradrenergic systems.

Slotkin TA, Skavicus S, Seidler FJ.

Brain Res Bull. 2017 Apr;130:268-273. doi: 10.1016/j.brainresbull.2017.02.004. Epub 2017 Feb 21.

11.
12.

Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products.

England LJ, Aagaard K, Bloch M, Conway K, Cosgrove K, Grana R, Gould TJ, Hatsukami D, Jensen F, Kandel D, Lanphear B, Leslie F, Pauly JR, Neiderhiser J, Rubinstein M, Slotkin TA, Spindel E, Stroud L, Wakschlag L.

Neurosci Biobehav Rev. 2017 Jan;72:176-189. doi: 10.1016/j.neubiorev.2016.11.013. Epub 2016 Nov 24. Review.

13.

Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes.

Slotkin TA, Skavicus S, Card J, Levin ED, Seidler FJ.

Toxicology. 2016 Nov 30;372:42-51. doi: 10.1016/j.tox.2016.10.015. Epub 2016 Nov 2.

14.

Is There a Critical Period for the Developmental Neurotoxicity of Low-Level Tobacco Smoke Exposure?

Slotkin TA, Stadler A, Skavicus S, Card J, Ruff J, Levin ED, Seidler FJ.

Toxicol Sci. 2017 Jan;155(1):75-84. doi: 10.1093/toxsci/kfw180. Epub 2016 Sep 14.

15.

Adolescents and adults differ in the immediate and long-term impact of nicotine administration and withdrawal on cardiac norepinephrine.

Slotkin TA, Stadler A, Skavicus S, Seidler FJ.

Brain Res Bull. 2016 Apr;122:71-5. doi: 10.1016/j.brainresbull.2016.03.006. Epub 2016 Mar 15.

16.

Cognitive and Behavioral Impairments Evoked by Low-Level Exposure to Tobacco Smoke Components: Comparison with Nicotine Alone.

Hall BJ, Cauley M, Burke DA, Kiany A, Slotkin TA, Levin ED.

Toxicol Sci. 2016 Jun;151(2):236-44. doi: 10.1093/toxsci/kfw042. Epub 2016 Feb 26.

17.

Prenatal drug exposures sensitize noradrenergic circuits to subsequent disruption by chlorpyrifos.

Slotkin TA, Skavicus S, Seidler FJ.

Toxicology. 2015 Dec 2;338:8-16. doi: 10.1016/j.tox.2015.09.005. Epub 2015 Sep 28.

18.

Developmental Neurotoxicity of Tobacco Smoke Directed Toward Cholinergic and Serotonergic Systems: More Than Just Nicotine.

Slotkin TA, Skavicus S, Card J, Stadler A, Levin ED, Seidler FJ.

Toxicol Sci. 2015 Sep;147(1):178-89. doi: 10.1093/toxsci/kfv123. Epub 2015 Jun 16.

19.

Amelioration strategies fail to prevent tobacco smoke effects on neurodifferentiation: Nicotinic receptor blockade, antioxidants, methyl donors.

Slotkin TA, Skavicus S, Card J, Levin ED, Seidler FJ.

Toxicology. 2015 Jul 3;333:63-75. doi: 10.1016/j.tox.2015.04.005. Epub 2015 Apr 17.

20.

Prenatal nicotine changes the response to postnatal chlorpyrifos: Interactions targeting serotonergic synaptic function and cognition.

Slotkin TA, Skavicus S, Levin ED, Seidler FJ.

Brain Res Bull. 2015 Feb;111:84-96. doi: 10.1016/j.brainresbull.2015.01.003. Epub 2015 Jan 12.

21.

Prenatal nicotine alters the developmental neurotoxicity of postnatal chlorpyrifos directed toward cholinergic systems: better, worse, or just "different?".

Slotkin TA, Seidler FJ.

Brain Res Bull. 2015 Jan;110:54-67. doi: 10.1016/j.brainresbull.2014.12.003. Epub 2014 Dec 12.

22.

Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene.

Slotkin TA, Card J, Stadler A, Levin ED, Seidler FJ.

Neurotoxicol Teratol. 2014 May-Jun;43:19-24. doi: 10.1016/j.ntt.2014.03.002. Epub 2014 Mar 15.

23.
24.

Prenatal dexamethasone, as used in preterm labor, worsens the impact of postnatal chlorpyrifos exposure on serotonergic pathways.

Slotkin TA, Card J, Seidler FJ.

Brain Res Bull. 2014 Jan;100:44-54. doi: 10.1016/j.brainresbull.2013.10.014. Epub 2013 Nov 23.

25.

Prenatal dexamethasone augments the neurobehavioral teratology of chlorpyrifos: significance for maternal stress and preterm labor.

Levin ED, Cauley M, Johnson JE, Cooper EM, Stapleton HM, Ferguson PL, Seidler FJ, Slotkin TA.

Neurotoxicol Teratol. 2014 Jan-Feb;41:35-42. doi: 10.1016/j.ntt.2013.10.004. Epub 2013 Oct 28.

26.

Maternal smoking and conduct disorder in the offspring.

Slotkin TA.

JAMA Psychiatry. 2013 Sep;70(9):901-2. No abstract available.

PMID:
23884399
27.

Does thyroid disruption contribute to the developmental neurotoxicity of chlorpyrifos?

Slotkin TA, Cooper EM, Stapleton HM, Seidler FJ.

Environ Toxicol Pharmacol. 2013 Sep;36(2):284-287. doi: 10.1016/j.etap.2013.04.003. Epub 2013 Apr 21.

28.

Adverse benzo[a]pyrene effects on neurodifferentiation are altered by other neurotoxicant coexposures: interactions with dexamethasone, chlorpyrifos, or nicotine in PC12 cells.

Slotkin TA, Card J, Seidler FJ.

Environ Health Perspect. 2013 Jul;121(7):825-31. doi: 10.1289/ehp.1306528. Epub 2013 Apr 19.

29.

BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells.

Slotkin TA, Card J, Infante A, Seidler FJ.

Neurotoxicol Teratol. 2013 May-Jun;37:13-7. doi: 10.1016/j.ntt.2013.02.001. Epub 2013 Feb 16.

30.

Prenatal dexamethasone augments the sex-selective developmental neurotoxicity of chlorpyrifos: implications for vulnerability after pharmacotherapy for preterm labor.

Slotkin TA, Card J, Infante A, Seidler FJ.

Neurotoxicol Teratol. 2013 May-Jun;37:1-12. doi: 10.1016/j.ntt.2013.02.002. Epub 2013 Feb 14.

31.

Branched-chain amino acids alter neurobehavioral function in rats.

Coppola A, Wenner BR, Ilkayeva O, Stevens RD, Maggioni M, Slotkin TA, Levin ED, Newgard CB.

Am J Physiol Endocrinol Metab. 2013 Feb 15;304(4):E405-13. doi: 10.1152/ajpendo.00373.2012. Epub 2012 Dec 18.

32.

Evaluation of the association between maternal smoking, childhood obesity, and metabolic disorders: a national toxicology program workshop review.

Behl M, Rao D, Aagaard K, Davidson TL, Levin ED, Slotkin TA, Srinivasan S, Wallinga D, White MF, Walker VR, Thayer KA, Holloway AC.

Environ Health Perspect. 2013 Feb;121(2):170-80. doi: 10.1289/ehp.1205404. Epub 2012 Dec 11. Review.

33.
34.

Chlorpyrifos developmental neurotoxicity: interaction with glucocorticoids in PC12 cells.

Slotkin TA, Card J, Seidler FJ.

Neurotoxicol Teratol. 2012 Sep-Oct;34(5):505-12. doi: 10.1016/j.ntt.2012.07.002. Epub 2012 Jul 14.

35.

Brain anomalies in children exposed prenatally to a common organophosphate pesticide.

Rauh VA, Perera FP, Horton MK, Whyatt RM, Bansal R, Hao X, Liu J, Barr DB, Slotkin TA, Peterson BS.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):7871-6. doi: 10.1073/pnas.1203396109. Epub 2012 Apr 30.

36.

Does mechanism matter? Unrelated neurotoxicants converge on cell cycle and apoptosis during neurodifferentiation.

Slotkin TA, Seidler FJ.

Neurotoxicol Teratol. 2012 Jul;34(4):395-402. doi: 10.1016/j.ntt.2012.04.008. Epub 2012 Apr 24.

37.

Developmental neurotoxicity of organophosphates targets cell cycle and apoptosis, revealed by transcriptional profiles in vivo and in vitro.

Slotkin TA, Seidler FJ.

Neurotoxicol Teratol. 2012 Mar;34(2):232-41. doi: 10.1016/j.ntt.2011.12.001. Epub 2011 Dec 28.

38.

Developmental exposure to organophosphates triggers transcriptional changes in genes associated with Parkinson's disease in vitro and in vivo.

Slotkin TA, Seidler FJ.

Brain Res Bull. 2011 Nov 25;86(5-6):340-7. doi: 10.1016/j.brainresbull.2011.09.017. Epub 2011 Sep 28.

39.

Mimicking maternal smoking and pharmacotherapy of preterm labor: fetal nicotine exposure enhances the effect of late gestational dexamethasone treatment on noradrenergic circuits.

Slotkin TA, Seidler FJ.

Brain Res Bull. 2011 Nov 25;86(5-6):435-40. doi: 10.1016/j.brainresbull.2011.08.009. Epub 2011 Aug 19.

40.

Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by allographic transplantation of adult subventricular zone-derived neural stem cells.

Turgeman G, Pinkas A, Slotkin TA, Tfilin M, Langford R, Yanai J.

J Neurosci Res. 2011 Aug;89(8):1185-93. doi: 10.1002/jnr.22631. Epub 2011 Apr 21.

PMID:
21520219
41.

Developmental neurotoxicity targeting hepatic and cardiac sympathetic innervation: effects of organophosphates are distinct from those of glucocorticoids.

Seidler FJ, Slotkin TA.

Brain Res Bull. 2011 May 30;85(3-4):225-30. doi: 10.1016/j.brainresbull.2011.03.021. Epub 2011 Mar 29.

42.
43.

Silver nanoparticles alter zebrafish development and larval behavior: distinct roles for particle size, coating and composition.

Powers CM, Slotkin TA, Seidler FJ, Badireddy AR, Padilla S.

Neurotoxicol Teratol. 2011 Nov-Dec;33(6):708-14. doi: 10.1016/j.ntt.2011.02.002. Epub 2011 Feb 22.

44.

Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells.

Dishaw LV, Powers CM, Ryde IT, Roberts SC, Seidler FJ, Slotkin TA, Stapleton HM.

Toxicol Appl Pharmacol. 2011 Nov 1;256(3):281-9. doi: 10.1016/j.taap.2011.01.005. Epub 2011 Jan 19.

45.

Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes.

Powers CM, Levin ED, Seidler FJ, Slotkin TA.

Neurotoxicol Teratol. 2011 Mar-Apr;33(2):329-32. doi: 10.1016/j.ntt.2010.10.006. Epub 2010 Oct 28.

46.

Does early-life exposure to organophosphate insecticides lead to prediabetes and obesity?

Slotkin TA.

Reprod Toxicol. 2011 Apr;31(3):297-301. doi: 10.1016/j.reprotox.2010.07.012. Epub 2010 Sep 17. Review.

47.

Silver nanoparticles compromise neurodevelopment in PC12 cells: critical contributions of silver ion, particle size, coating, and composition.

Powers CM, Badireddy AR, Ryde IT, Seidler FJ, Slotkin TA.

Environ Health Perspect. 2011 Jan;119(1):37-44. doi: 10.1289/ehp.1002337. Epub 2010 Sep 14.

49.

Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants.

Slotkin TA, Lobner D, Seidler FJ.

Brain Res Bull. 2010 Aug 30;83(1-2):76-83. doi: 10.1016/j.brainresbull.2010.06.010. Epub 2010 Jun 25.

50.

Acute spinal cord injury persistently reduces R/G RNA editing of AMPA receptors.

Barbon A, Fumagalli F, Caracciolo L, Madaschi L, Lesma E, Mora C, Carelli S, Slotkin TA, Racagni G, Di Giulio AM, Gorio A, Barlati S.

J Neurochem. 2010 Jul;114(2):397-407. doi: 10.1111/j.1471-4159.2010.06767.x. Epub 2010 Apr 23.

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