Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 390


Relevance of Vitamin D in Melanoma Development, Progression and Therapy.

Brożyna AA, Hoffman RM, Slominski AT.

Anticancer Res. 2020 Jan;40(1):473-489. doi: 10.21873/anticanres.13976. Review.


Characterization of serotonin and N-acetylserotonin systems in the human epidermis and skin cells.

Slominski AT, Kim TK, Kleszczyński K, Semak I, Janjetovic Z, Sweatman T, Skobowiat C, Steketee JD, Lin Z, Postlethwaite A, Li W, Reiter RJ, Tobin DJ.

J Pineal Res. 2019 Nov 26:e12626. doi: 10.1111/jpi.12626. [Epub ahead of print]


Melatonin exerts oncostatic capacity and decreases melanogenesis in human MNT-1 melanoma cells.

Kleszczyński K, Kim TK, Bilska B, Sarna M, Mokrzynski K, Stegemann A, Pyza E, Reiter RJ, Steinbrink K, Böhm M, Slominski AT.

J Pineal Res. 2019 Nov;67(4):e12610. doi: 10.1111/jpi.12610. Epub 2019 Oct 7.


Coriolus versicolor-derived protein-bound polysaccharides trigger the caspase-independent cell death pathway in amelanotic but not melanotic melanoma cells.

Pawlikowska M, Piotrowski J, Jędrzejewski T, Kozak W, Slominski AT, Brożyna AA.

Phytother Res. 2020 Jan;34(1):173-183. doi: 10.1002/ptr.6513. Epub 2019 Sep 12.


On the relationship between VDR, RORα and RORγ receptors expression and HIF1-α levels in human melanomas.

Brożyna AA, Jóźwicki W, Jetten AM, Slominski AT.

Exp Dermatol. 2019 Sep;28(9):1036-1043. doi: 10.1111/exd.14002. Epub 2019 Aug 8.


Targeting melanocortin receptor type 1 with small peptides.

Slominski AT, Slominski RM, Zmijewski MA.

Br J Dermatol. 2019 Jul;181(1):17-18. doi: 10.1111/bjd.18022. No abstract available.


Vitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levels.

Markiewicz A, Brożyna AA, Podgórska E, Elas M, Urbańska K, Jetten AM, Slominski AT, Jóźwicki W, Orłowska-Heitzman J, Dyduch G, Romanowska-Dixon B.

Sci Rep. 2019 Jun 24;9(1):9142. doi: 10.1038/s41598-019-45161-8.


Neuroendocrine Aspects of Skin Aging.

Bocheva G, Slominski RM, Slominski AT.

Int J Mol Sci. 2019 Jun 7;20(11). pii: E2798. doi: 10.3390/ijms20112798. Review.


Essential skin shrinkage: cicatricial ectropion, a histopathologic evaluation and clinical analysis.

Culter-Peck CM, Dryden SC, Fowler BT, Kovacic D, Slominski A, Fleming JC.

Orbit. 2019 May 20:1-5. doi: 10.1080/01676830.2019.1600152. [Epub ahead of print]


Genomic Profiling of the Steroidogenic Acute Regulatory Protein in Breast Cancer: In Silico Assessments and a Mechanistic Perspective.

Manna PR, Ahmed AU, Yang S, Narasimhan M, Cohen-Tannoudji J, Slominski AT, Pruitt K.

Cancers (Basel). 2019 May 4;11(5). pii: E623. doi: 10.3390/cancers11050623.


Protective effects of novel derivatives of vitamin D3 and lumisterol against UVB-induced damage in human keratinocytes involve activation of Nrf2 and p53 defense mechanisms.

Chaiprasongsuk A, Janjetovic Z, Kim TK, Jarrett SG, D'Orazio JA, Holick MF, Tang EKY, Tuckey RC, Panich U, Li W, Slominski AT.

Redox Biol. 2019 Jun;24:101206. doi: 10.1016/j.redox.2019.101206. Epub 2019 Apr 20.


Vitamin D and its low calcemic analogs modulate the anticancer properties of cisplatin and dacarbazine in the human melanoma A375 cell line.

Piotrowska A, Wierzbicka J, Rybarczyk A, Tuckey RC, Slominski AT, Żmijewski MA.

Int J Oncol. 2019 Apr;54(4):1481-1495. doi: 10.3892/ijo.2019.4725. Epub 2019 Feb 25.


Melatonin and Its Metabolites Ameliorate UVR-Induced Mitochondrial Oxidative Stress in Human MNT-1 Melanoma Cells.

Kleszczyński K, Bilska B, Stegemann A, Flis DJ, Ziolkowski W, Pyza E, Luger TA, Reiter RJ, Böhm M, Slominski AT.

Int J Mol Sci. 2018 Nov 28;19(12). pii: E3786. doi: 10.3390/ijms19123786.


Differential and Overlapping Effects of 20,23(OH)₂D3 and 1,25(OH)₂D3 on Gene Expression in Human Epidermal Keratinocytes: Identification of AhR as an Alternative Receptor for 20,23(OH)₂D3.

Slominski AT, Kim TK, Janjetovic Z, Brożyna AA, Żmijewski MA, Xu H, Sutter TR, Tuckey RC, Jetten AM, Crossman DK.

Int J Mol Sci. 2018 Oct 8;19(10). pii: E3072. doi: 10.3390/ijms19103072.


The serum vitamin D metabolome: What we know and what is still to discover.

Tuckey RC, Cheng CYS, Slominski AT.

J Steroid Biochem Mol Biol. 2019 Feb;186:4-21. doi: 10.1016/j.jsbmb.2018.09.003. Epub 2018 Sep 8. Review.


Antiproliferative Activity of Non-Calcemic Vitamin D Analogs on Human Melanoma Lines in Relation to VDR and PDIA3 Receptors.

Wasiewicz T, Piotrowska A, Wierzbicka J, Slominski AT, Zmijewski MA.

Int J Mol Sci. 2018 Aug 31;19(9). pii: E2583. doi: 10.3390/ijms19092583.


Acute hepatologic and nephrologic effects of calcitriol in Syrian golden hamster (Mesocricetus auratus).

Podgorska E, Sniegocka M, Mycinska M, Trybus W, Trybus E, Kopacz-Bednarska A, Wiechec O, Krzykawska-Serda M, Elas M, Krol T, Urbanska K, Slominski A.

Acta Biochim Pol. 2018;65(3):351-358. doi: 10.18388/abp.2018_2626. Epub 2018 Jul 17.


Calcitriol and Calcidiol Can Sensitize Melanoma Cells to Low⁻LET Proton Beam Irradiation.

Podgorska E, Drzal A, Matuszak Z, Swakon J, Slominski A, Elas M, Urbanska K.

Int J Mol Sci. 2018 Jul 31;19(8). pii: E2236. doi: 10.3390/ijms19082236.


Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function.

Singh B, Schoeb TR, Bajpai P, Slominski A, Singh KK.

Cell Death Dis. 2018 Jul 20;9(7):735. doi: 10.1038/s41419-018-0765-9.


Melatonin and its derivatives counteract the ultraviolet B radiation-induced damage in human and porcine skin ex vivo.

Skobowiat C, Brożyna AA, Janjetovic Z, Jeayeng S, Oak ASW, Kim TK, Panich U, Reiter RJ, Slominski AT.

J Pineal Res. 2018 Sep;65(2):e12501. doi: 10.1111/jpi.12501. Epub 2018 May 21.


Transplantable Melanomas in Hamsters and Gerbils as Models for Human Melanoma. Sensitization in Melanoma Radiotherapy-From Animal Models to Clinical Trials.

Śniegocka M, Podgórska E, Płonka PM, Elas M, Romanowska-Dixon B, Szczygieł M, Żmijewski MA, Cichorek M, Markiewicz A, Brożyna AA, Słominski AT, Urbańska K.

Int J Mol Sci. 2018 Apr 1;19(4). pii: E1048. doi: 10.3390/ijms19041048. Review.


Retinoic acid-related Orphan Receptor γ (RORγ): connecting sterol metabolism to regulation of the immune system and autoimmune disease.

Jetten AM, Takeda Y, Slominski A, Kang HS.

Curr Opin Toxicol. 2018 Apr;8:66-80. doi: 10.1016/j.cotox.2018.01.005. Epub 2018 Feb 1.


How UV Light Touches the Brain and Endocrine System Through Skin, and Why.

Slominski AT, Zmijewski MA, Plonka PM, Szaflarski JP, Paus R.

Endocrinology. 2018 May 1;159(5):1992-2007. doi: 10.1210/en.2017-03230. Review.


CYP27A1 acts on the pre-vitamin D3 photoproduct, lumisterol, producing biologically active hydroxy-metabolites.

Tuckey RC, Li W, Ma D, Cheng CYS, Wang KM, Kim TK, Jeayeng S, Slominski AT.

J Steroid Biochem Mol Biol. 2018 Jul;181:1-10. doi: 10.1016/j.jsbmb.2018.02.008. Epub 2018 Feb 13.


Melatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions.

Slominski AT, Hardeland R, Zmijewski MA, Slominski RM, Reiter RJ, Paus R.

J Invest Dermatol. 2018 Mar;138(3):490-499. doi: 10.1016/j.jid.2017.10.025. Epub 2018 Feb 7. Review.


CKS1 expression in melanocytic nevi and melanoma.

Brożyna AA, Aplin A, Cohen C, Carlson G, Page AJ, Murphy M, Slominski AT, Carlson JA.

Oncotarget. 2017 Dec 23;9(3):4173-4187. doi: 10.18632/oncotarget.23648. eCollection 2018 Jan 9.


Investigation of 20S-hydroxyvitamin D3 analogs and their 1α-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities.

Lin Z, Marepally SR, Goh ESY, Cheng CYS, Janjetovic Z, Kim TK, Miller DD, Postlethwaite AE, Slominski AT, Tuckey RC, Peluso-Iltis C, Rochel N, Li W.

Sci Rep. 2018 Jan 24;8(1):1478. doi: 10.1038/s41598-018-19183-7.


Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols.

Slominski AT, Kim TK, Hobrath JV, Janjetovic Z, Oak ASW, Postlethwaite A, Lin Z, Li W, Takeda Y, Jetten AM, Tuckey RC.

Sci Rep. 2017 Sep 12;7(1):11434. doi: 10.1038/s41598-017-10202-7.


1α,20S-Dihydroxyvitamin D3 Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis.

Lin Z, Chen H, Belorusova AY, Bollinger JC, Tang EKY, Janjetovic Z, Kim TK, Wu Z, Miller DD, Slominski AT, Postlethwaite AE, Tuckey RC, Rochel N, Li W.

Sci Rep. 2017 Aug 31;7(1):10193. doi: 10.1038/s41598-017-10917-7.


Pigmented Epithelioid Melanocytoma (PEM)/Animal Type Melanoma (ATM): Quest for an Origin. Report of One Unusual Case Indicating Follicular Origin and Another Arising in an Intradermal Nevus.

Tarasen A, Carlson JA, Leonard MK, Merlino G, Kaetzel D, Slominski AT.

Int J Mol Sci. 2017 Aug 15;18(8). pii: E1769. doi: 10.3390/ijms18081769.


Melatonin, mitochondria, and the skin.

Slominski AT, Zmijewski MA, Semak I, Kim TK, Janjetovic Z, Slominski RM, Zmijewski JW.

Cell Mol Life Sci. 2017 Nov;74(21):3913-3925. doi: 10.1007/s00018-017-2617-7. Epub 2017 Aug 12. Review.


The HGF/SF Mouse Model of UV-Induced Melanoma as an In Vivo Sensor for Metastasis-Regulating Gene.

Leonard MK, Pamidimukkala N, Puts GS, Snyder DE, Slominski AT, Kaetzel DM.

Int J Mol Sci. 2017 Jul 28;18(8). pii: E1647. doi: 10.3390/ijms18081647. Review.


Cutaneous Glucocorticoidogenesis and Cortisol Signaling Are Defective in Psoriasis.

Slominski AT, Brożyna AA, Tuckey RC.

J Invest Dermatol. 2017 Aug;137(8):1609-1611. doi: 10.1016/j.jid.2017.04.004. Review.


Properties of purified CYP2R1 in a reconstituted membrane environment and its 25-hydroxylation of 20-hydroxyvitamin D3.

Cheng CYS, Kim TK, Jeayeng S, Slominski AT, Tuckey RC.

J Steroid Biochem Mol Biol. 2018 Mar;177:59-69. doi: 10.1016/j.jsbmb.2017.07.011. Epub 2017 Jul 14.


Melanin pigmentation and melanoma.

Picardo M, Slominski AT.

Exp Dermatol. 2017 Jul;26(7):555-556. doi: 10.1111/exd.13400. No abstract available.


On the role of classical and novel forms of vitamin D in melanoma progression and management.

Slominski AT, Brożyna AA, Skobowiat C, Zmijewski MA, Kim TK, Janjetovic Z, Oak AS, Jozwicki W, Jetten AM, Mason RS, Elmets C, Li W, Hoffman RM, Tuckey RC.

J Steroid Biochem Mol Biol. 2018 Mar;177:159-170. doi: 10.1016/j.jsbmb.2017.06.013. Epub 2017 Jul 1. Review.


Inflammatory melanoma in transit metastases with complete response to talimogene laherparepvec.

Blackmon JT, Stratton MS, Kwak Y, Pavlidakey PG, Slominski AT, McKee SB, Viator TM, Kim JY, Huang CC, Conry RM.

JAAD Case Rep. 2017 Jun 16;3(4):280-283. doi: 10.1016/j.jdcr.2017.02.011. eCollection 2017 Jul. No abstract available.


Nrf2 in keratinocytes modulates UVB-induced DNA damage and apoptosis in melanocytes through MAPK signaling.

Jeayeng S, Wongkajornsilp A, Slominski AT, Jirawatnotai S, Sampattavanich S, Panich U.

Free Radic Biol Med. 2017 Jul;108:918-928. doi: 10.1016/j.freeradbiomed.2017.05.009. Epub 2017 May 8.


Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways.

Janjetovic Z, Jarrett SG, Lee EF, Duprey C, Reiter RJ, Slominski AT.

Sci Rep. 2017 Apr 28;7(1):1274. doi: 10.1038/s41598-017-01305-2.


Glucocorticoids Inhibit Wound Healing: Novel Mechanism of Action.

Slominski AT, Zmijewski MA.

J Invest Dermatol. 2017 May;137(5):1012-1014. doi: 10.1016/j.jid.2017.01.024.


Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management.

Slominski AT, Brożyna AA, Zmijewski MA, Jóźwicki W, Jetten AM, Mason RS, Tuckey RC, Elmets CA.

Lab Invest. 2017 Jun;97(6):706-724. doi: 10.1038/labinvest.2017.3. Epub 2017 Feb 20. Review.


Noncalcemic 20-hydroxyvitamin D3 inhibits human melanoma growth in in vitro and in vivo models.

Skobowiat C, Oak AS, Kim TK, Yang CH, Pfeffer LM, Tuckey RC, Slominski AT.

Oncotarget. 2017 Feb 7;8(6):9823-9834. doi: 10.18632/oncotarget.14193.


TRPM1 (melastatin) expression is an independent predictor of overall survival in clinical AJCC stage I and II melanoma patients.

Brożyna AA, Guo H, Yang SE, Cornelius L, Linette G, Murphy M, Sheehan C, Ross J, Slominski A, Carlson JA.

J Cutan Pathol. 2017 Apr;44(4):328-337. doi: 10.1111/cup.12872. Epub 2017 Jan 26.


Skin Exposure to Ultraviolet B Rapidly Activates Systemic Neuroendocrine and Immunosuppressive Responses.

Skobowiat C, Postlethwaite AE, Slominski AT.

Photochem Photobiol. 2017 Jul;93(4):1008-1015. doi: 10.1111/php.12642. Epub 2016 Nov 1.


Skin steroidogenesis in health and disease.

Nikolakis G, Stratakis CA, Kanaki T, Slominski A, Zouboulis CC.

Rev Endocr Metab Disord. 2016 Sep;17(3):247-258. Review.


Giant Basal Cell Carcinomas Express Neuroactive Mediators and Show a High Growth Rate: A Case-Control Study and Meta-Analysis of Etiopathogenic and Prognostic Factors.

Yazdani Abyaneh MA, Engel P, Slominski A, Ragsdale B, Agag R, Cramer D, Carlson JA.

Am J Dermatopathol. 2017 Mar;39(3):189-194. doi: 10.1097/DAD.0000000000000640.


RORα is not a receptor for melatonin (response to DOI 10.1002/bies.201600018).

Slominski AT, Zmijewski MA, Jetten AM.

Bioessays. 2016 Dec;38(12):1193-1194. doi: 10.1002/bies.201600204. Epub 2016 Oct 14. No abstract available.


Endogenously produced nonclassical vitamin D hydroxy-metabolites act as "biased" agonists on VDR and inverse agonists on RORα and RORγ.

Slominski AT, Kim TK, Hobrath JV, Oak ASW, Tang EKY, Tieu EW, Li W, Tuckey RC, Jetten AM.

J Steroid Biochem Mol Biol. 2017 Oct;173:42-56. doi: 10.1016/j.jsbmb.2016.09.024. Epub 2016 Sep 28. Review.


Pregnancy-driven cardiovascular maternal miR-29 plasticity in obesity.

Schlabritz-Loutsevitch N, Apostolakis-Kyrus K, Krutilina R, Hubbard G, Kocak M, Janjetovic Z, Sathanandam S, Slominski AT, Mari G, Dick E Jr.

J Med Primatol. 2016 Dec;45(6):297-303. doi: 10.1111/jmp.12236. Epub 2016 Sep 15.


Metabolism of melatonin in the skin: Why is it important?

Slominski AT, Semak I, Fischer TW, Kim TK, Kleszczyński K, Hardeland R, Reiter RJ.

Exp Dermatol. 2017 Jul;26(7):563-568. doi: 10.1111/exd.13208. Epub 2017 Mar 23.

Supplemental Content

Loading ...
Support Center