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Items: 40


Interactions and activities of factors involved in the late stages of human 18S rRNA maturation.

Sloan KE, Knox AA, Wells GR, Schneider C, Watkins NJ.

RNA Biol. 2019 Jan 13:1-15. doi: 10.1080/15476286.2018.1564467. [Epub ahead of print]


The human RNA helicase DHX37 is required for release of the U3 snoRNP from pre-ribosomal particles.

Choudhury P, Hackert P, Memet I, Sloan KE, Bohnsack MT.

RNA Biol. 2018 Dec 24. doi: 10.1080/15476286.2018.1556149. [Epub ahead of print]


RNA helicases mediate structural transitions and compositional changes in pre-ribosomal complexes.

Brüning L, Hackert P, Martin R, Davila Gallesio J, Aquino GRR, Urlaub H, Sloan KE, Bohnsack MT.

Nat Commun. 2018 Dec 19;9(1):5383. doi: 10.1038/s41467-018-07783-w.


N6 -Methyladenosine-Sensitive RNA-Cleaving Deoxyribozymes.

Sednev MV, Mykhailiuk V, Choudhury P, Halang J, Sloan KE, Bohnsack MT, Höbartner C.

Angew Chem Int Ed Engl. 2018 Nov 12;57(46):15117-15121. doi: 10.1002/anie.201808745. Epub 2018 Oct 24.


The m6A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5'-3' exoribonuclease XRN1.

Kretschmer J, Rao H, Hackert P, Sloan KE, Höbartner C, Bohnsack MT.

RNA. 2018 Oct;24(10):1339-1350. doi: 10.1261/rna.064238.117. Epub 2018 Jul 3.


Modifications in small nuclear RNAs and their roles in spliceosome assembly and function.

Bohnsack MT, Sloan KE.

Biol Chem. 2018 Oct 25;399(11):1265-1276. doi: 10.1515/hsz-2018-0205. Review.


Unravelling the Mechanisms of RNA Helicase Regulation.

Sloan KE, Bohnsack MT.

Trends Biochem Sci. 2018 Apr;43(4):237-250. doi: 10.1016/j.tibs.2018.02.001. Epub 2018 Feb 24. Review.


Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs.

Warda AS, Kretschmer J, Hackert P, Lenz C, Urlaub H, Höbartner C, Sloan KE, Bohnsack MT.

EMBO Rep. 2017 Nov;18(11):2004-2014. doi: 10.15252/embr.201744940. Epub 2017 Oct 19.


The mitochondrial epitranscriptome: the roles of RNA modifications in mitochondrial translation and human disease.

Bohnsack MT, Sloan KE.

Cell Mol Life Sci. 2018 Jan;75(2):241-260. doi: 10.1007/s00018-017-2598-6. Epub 2017 Jul 27. Review.


Corrigendum: A novel translational control mechanism involving RNA structures within coding sequences.

Jungfleisch J, Nedialkova DD, Dotu I, Sloan KE, Martinez-Bosch N, Brüning L, Raineri E, Navarro P, Bohnsack MT, Leidel SA, Díez J.

Genome Res. 2017 Apr;27(4):663. doi: 10.1101/gr.222133.117. No abstract available.


Crosslinking Methods to Identify RNA Methyltransferase Targets In Vivo.

Haag S, Kretschmer J, Sloan KE, Bohnsack MT.

Methods Mol Biol. 2017;1562:269-281. doi: 10.1007/978-1-4939-6807-7_18.


In Vitro Assays for RNA Methyltransferase Activity.

Haag S, Sloan KE, Höbartner C, Bohnsack MT.

Methods Mol Biol. 2017;1562:259-268. doi: 10.1007/978-1-4939-6807-7_17.


The ribosome biogenesis factor yUtp23/hUTP23 coordinates key interactions in the yeast and human pre-40S particle and hUTP23 contains an essential PIN domain.

Wells GR, Weichmann F, Sloan KE, Colvin D, Watkins NJ, Schneider C.

Nucleic Acids Res. 2017 May 5;45(8):4796-4809. doi: 10.1093/nar/gkw1344.


Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function.

Sloan KE, Warda AS, Sharma S, Entian KD, Lafontaine DLJ, Bohnsack MT.

RNA Biol. 2017 Sep 2;14(9):1138-1152. doi: 10.1080/15476286.2016.1259781. Epub 2016 Dec 2. Review.


A novel translational control mechanism involving RNA structures within coding sequences.

Jungfleisch J, Nedialkova DD, Dotu I, Sloan KE, Martinez-Bosch N, Brüning L, Raineri E, Navarro P, Bohnsack MT, Leidel SA, Díez J.

Genome Res. 2017 Jan;27(1):95-106. doi: 10.1101/gr.209015.116. Epub 2016 Nov 7. Erratum in: Genome Res. 2017 Apr;27(4):663.


Effects of the Bowen-Conradi syndrome mutation in EMG1 on its nuclear import, stability and nucleolar recruitment.

Warda AS, Freytag B, Haag S, Sloan KE, Görlich D, Bohnsack MT.

Hum Mol Genet. 2016 Dec 15;25(24):5353-5364. doi: 10.1093/hmg/ddw351.


How RNA modification allows non-conventional decoding in mitochondria.

Sloan KE, Höbartner C, Bohnsack MT.

Cell Cycle. 2017 Jan 17;16(2):145-146. doi: 10.1080/15384101.2016.1235860. Epub 2016 Sep 29. No abstract available.


NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translation.

Haag S, Sloan KE, Ranjan N, Warda AS, Kretschmer J, Blessing C, Hübner B, Seikowski J, Dennerlein S, Rehling P, Rodnina MV, Höbartner C, Bohnsack MT.

EMBO J. 2016 Oct 4;35(19):2104-2119. Epub 2016 Aug 5.


The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans.

Wells GR, Weichmann F, Colvin D, Sloan KE, Kudla G, Tollervey D, Watkins NJ, Schneider C.

Nucleic Acids Res. 2016 Oct 14;44(18):9016. Epub 2016 Jul 14. No abstract available.


The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans.

Wells GR, Weichmann F, Colvin D, Sloan KE, Kudla G, Tollervey D, Watkins NJ, Schneider C.

Nucleic Acids Res. 2016 Jun 20;44(11):5399-409. doi: 10.1093/nar/gkw213. Epub 2016 Mar 31. Erratum in: Nucleic Acids Res. 2016 Oct 14;44(18):9016.


Protein cofactor competition regulates the action of a multifunctional RNA helicase in different pathways.

Heininger AU, Hackert P, Andreou AZ, Boon KL, Memet I, Prior M, Clancy A, Schmidt B, Urlaub H, Schleiff E, Sloan KE, Deckers M, Lührmann R, Enderlein J, Klostermeier D, Rehling P, Bohnsack MT.

RNA Biol. 2016;13(3):320-30. doi: 10.1080/15476286.2016.1142038. Epub 2016 Jan 29.


Nucleocytoplasmic Transport of RNAs and RNA-Protein Complexes.

Sloan KE, Gleizes PE, Bohnsack MT.

J Mol Biol. 2016 May 22;428(10 Pt A):2040-59. doi: 10.1016/j.jmb.2015.09.023. Epub 2015 Oct 3. Review.


The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX21.

Sloan KE, Leisegang MS, Doebele C, Ramírez AS, Simm S, Safferthal C, Kretschmer J, Schorge T, Markoutsa S, Haag S, Karas M, Ebersberger I, Schleiff E, Watkins NJ, Bohnsack MT.

Nucleic Acids Res. 2015 Jan;43(1):553-64. doi: 10.1093/nar/gku1291. Epub 2014 Dec 4.


A pre-ribosomal RNA interaction network involving snoRNAs and the Rok1 helicase.

Martin R, Hackert P, Ruprecht M, Simm S, Brüning L, Mirus O, Sloan KE, Kudla G, Schleiff E, Bohnsack MT.

RNA. 2014 Aug;20(8):1173-82. doi: 10.1261/rna.044669.114. Epub 2014 Jun 19.


The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA.

Sloan KE, Bohnsack MT, Schneider C, Watkins NJ.

RNA. 2014 Apr;20(4):540-50. doi: 10.1261/rna.043471.113. Epub 2014 Feb 18.


The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress.

Sloan KE, Bohnsack MT, Watkins NJ.

Cell Rep. 2013 Oct 17;5(1):237-47. doi: 10.1016/j.celrep.2013.08.049. Epub 2013 Oct 10.


Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing.

Sloan KE, Mattijssen S, Lebaron S, Tollervey D, Pruijn GJ, Watkins NJ.

J Cell Biol. 2013 Mar 4;200(5):577-88. doi: 10.1083/jcb.201207131. Epub 2013 Feb 25.


Comparison of the yeast and human nuclear exosome complexes.

Sloan KE, Schneider C, Watkins NJ.

Biochem Soc Trans. 2012 Aug;40(4):850-5. doi: 10.1042/BST20120061. Review.


Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing.

van Nues RW, Granneman S, Kudla G, Sloan KE, Chicken M, Tollervey D, Watkins NJ.

EMBO J. 2011 May 10;30(12):2420-30. doi: 10.1038/emboj.2011.148.


Variation in age and physical status prior to total knee and hip replacement surgery: a comparison of centers in Australia and Europe.

Ackerman IN, Dieppe PA, March LM, Roos EM, Nilsdotter AK, Brown GC, Sloan KE, Osborne RH.

Arthritis Rheum. 2009 Feb 15;61(2):166-73. doi: 10.1002/art.24215.


Computer navigation of the acetabular component: a cadaver reliability study.

Spencer JM, Day RE, Sloan KE, Beaver RJ.

J Bone Joint Surg Br. 2006 Jul;88(7):972-5.


CD155/PVR enhances glioma cell dispersal by regulating adhesion signaling and focal adhesion dynamics.

Sloan KE, Stewart JK, Treloar AF, Matthews RT, Jay DG.

Cancer Res. 2005 Dec 1;65(23):10930-7.


Functional proteomic screen identifies a modulating role for CD44 in death receptor-mediated apoptosis.

Hauptschein RS, Sloan KE, Torella C, Moezzifard R, Giel-Moloney M, Zehetmeier C, Unger C, Ilag LL, Jay DG.

Cancer Res. 2005 Mar 1;65(5):1887-96.


CD155/PVR plays a key role in cell motility during tumor cell invasion and migration.

Sloan KE, Eustace BK, Stewart JK, Zehetmeier C, Torella C, Simeone M, Roy JE, Unger C, Louis DN, Ilag LL, Jay DG.

BMC Cancer. 2004 Oct 7;4:73.


Inhibition of alpha4 integrin protects against transient focal cerebral ischemia in normotensive and hypertensive rats.

Relton JK, Sloan KE, Frew EM, Whalley ET, Adams SP, Lobb RR.

Stroke. 2001 Jan;32(1):199-205.


Musculoskeletal effects of an electrical stimulation induced cycling programme in the spinal injured.

Sloan KE, Bremner LA, Byrne J, Day RE, Scull ER.

Paraplegia. 1994 Jun;32(6):407-15.


A clinical exercise system for paraplegics using functional electrical stimulation.

Bremner LA, Sloan KE, Day RE, Scull ER, Ackland T.

Paraplegia. 1992 Sep;30(9):647-55.


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