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Items: 43


Repurposing existing medications as cancer therapy: design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell transplantation.

Knight JM, Kerswill SA, Hari P, Cole SW, Logan BR, D'Souza A, Shah NN, Horowitz MM, Stolley MR, Sloan EK, Giles KE, Costanzo ES, Hamadani M, Chhabra S, Dhakal B, Rizzo JD.

BMC Cancer. 2018 May 24;18(1):593. doi: 10.1186/s12885-018-4509-0.


Predicting cancer cell invasion by single-cell physical phenotyping.

Nyberg KD, Bruce SL, Nguyen AV, Chan CK, Gill NK, Kim TH, Sloan EK, Rowat AC.

Integr Biol (Camb). 2018 Apr 23;10(4):218-231. doi: 10.1039/c7ib00222j.


Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells.

Paquet-Fifield S, Koh SL, Cheng L, Beyit LM, Shembrey C, Mølck C, Behrenbruch C, Papin M, Gironella M, Guelfi S, Nasr R, Grillet F, Prudhomme M, Bourgaux JF, Castells A, Pascussi JM, Heriot AG, Puisieux A, Davis MJ, Pannequin J, Hill AF, Sloan EK, Hollande F.

Cancer Res. 2018 Jun 1;78(11):2925-2938. doi: 10.1158/0008-5472.CAN-17-1869. Epub 2018 Mar 6.


Perioperative events influence cancer recurrence risk after surgery.

Hiller JG, Perry NJ, Poulogiannis G, Riedel B, Sloan EK.

Nat Rev Clin Oncol. 2018 Apr;15(4):205-218. doi: 10.1038/nrclinonc.2017.194. Epub 2017 Dec 28. Review.


β-Adrenergic Signaling Impairs Antitumor CD8+ T-cell Responses to B-cell Lymphoma Immunotherapy.

Nissen MD, Sloan EK, Mattarollo SR.

Cancer Immunol Res. 2018 Jan;6(1):98-109. doi: 10.1158/2326-6066.CIR-17-0401. Epub 2017 Nov 16.


Implicating anaesthesia and the perioperative period in cancer recurrence and metastasis.

Dubowitz JA, Sloan EK, Riedel BJ.

Clin Exp Metastasis. 2017 Sep 11. doi: 10.1007/s10585-017-9862-x. [Epub ahead of print]


Social regulation of the lymph node transcriptome in rhesus macaques (Macaca mulatta).

Chun K, Capitanio JP, Lamkin DM, Sloan EK, Arevalo JM, Cole SW.

Psychoneuroendocrinology. 2017 Feb;76:107-113. doi: 10.1016/j.psyneuen.2016.10.029. Epub 2016 Nov 14.


Cancer cells become less deformable and more invasive with activation of β-adrenergic signaling.

Kim TH, Gill NK, Nyberg KD, Nguyen AV, Hohlbauch SV, Geisse NA, Nowell CJ, Sloan EK, Rowat AC.

J Cell Sci. 2016 Dec 15;129(24):4563-4575. Epub 2016 Nov 14.


Optimized Method for Untargeted Metabolomics Analysis of MDA-MB-231 Breast Cancer Cells.

Peterson AL, Walker AK, Sloan EK, Creek DJ.

Metabolites. 2016 Sep 22;6(4). pii: E30. doi: 10.3390/metabo6040030.


Stress-driven lymphatic dissemination: An unanticipated consequence of communication between the sympathetic nervous system and lymphatic vasculature.

Le CP, Sloan EK.

Mol Cell Oncol. 2016 May 31;3(4):e1177674. doi: 10.1080/23723556.2016.1177674. eCollection 2016 Jul.


β-Adrenergic-stimulated macrophages: Comprehensive localization in the M1-M2 spectrum.

Lamkin DM, Ho HY, Ong TH, Kawanishi CK, Stoffers VL, Ahlawat N, Ma JCY, Arevalo JMG, Cole SW, Sloan EK.

Brain Behav Immun. 2016 Oct;57:338-346. doi: 10.1016/j.bbi.2016.07.162. Epub 2016 Jul 30.


Neural regulation of cancer: from mechanobiology to inflammation.

Kim TH, Rowat AC, Sloan EK.

Clin Transl Immunology. 2016 May 13;5(5):e78. doi: 10.1038/cti.2016.18. eCollection 2016 May. Review.


β2-Adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancer.

Chang A, Le CP, Walker AK, Creed SJ, Pon CK, Albold S, Carroll D, Halls ML, Lane JR, Riedel B, Ferrari D, Sloan EK.

Brain Behav Immun. 2016 Oct;57:106-115. doi: 10.1016/j.bbi.2016.06.011. Epub 2016 Jun 16.


Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination.

Le CP, Nowell CJ, Kim-Fuchs C, Botteri E, Hiller JG, Ismail H, Pimentel MA, Chai MG, Karnezis T, Rotmensz N, Renne G, Gandini S, Pouton CW, Ferrari D, Möller A, Stacker SA, Sloan EK.

Nat Commun. 2016 Mar 1;7:10634. doi: 10.1038/ncomms10634.


β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion.

Creed SJ, Le CP, Hassan M, Pon CK, Albold S, Chan KT, Berginski ME, Huang Z, Bear JE, Lane JR, Halls ML, Ferrari D, Nowell CJ, Sloan EK.

Breast Cancer Res. 2015 Nov 25;17(1):145. doi: 10.1186/s13058-015-0655-3.


The β2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasion.

Pon CK, Lane JR, Sloan EK, Halls ML.

FASEB J. 2016 Mar;30(3):1144-54. doi: 10.1096/fj.15-277798. Epub 2015 Nov 17.


Neural Regulation of Pancreatic Cancer: A Novel Target for Intervention.

Chang A, Kim-Fuchs C, Le CP, Hollande F, Sloan EK.

Cancers (Basel). 2015 Jul 17;7(3):1292-312. doi: 10.3390/cancers7030838. Review.


Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats.

Kaminskas LM, McLeod VM, Ascher DB, Ryan GM, Jones S, Haynes JM, Trevaskis NL, Chan LJ, Sloan EK, Finnin BA, Williamson M, Velkov T, Williams ED, Kelly BD, Owen DJ, Porter CJ.

Mol Pharm. 2015 Feb 2;12(2):432-43. doi: 10.1021/mp500531e. Epub 2015 Jan 20.


α2-Adrenergic blockade mimics the enhancing effect of chronic stress on breast cancer progression.

Lamkin DM, Sung HY, Yang GS, David JM, Ma JC, Cole SW, Sloan EK.

Psychoneuroendocrinology. 2015 Jan;51:262-70. doi: 10.1016/j.psyneuen.2014.10.004. Epub 2014 Oct 12.


Chronic stress accelerates pancreatic cancer growth and invasion: a critical role for beta-adrenergic signaling in the pancreatic microenvironment.

Kim-Fuchs C, Le CP, Pimentel MA, Shackleford D, Ferrari D, Angst E, Hollande F, Sloan EK.

Brain Behav Immun. 2014 Aug;40:40-7. doi: 10.1016/j.bbi.2014.02.019. Epub 2014 Mar 17.


Lymphovascular and neural regulation of metastasis: shared tumour signalling pathways and novel therapeutic approaches.

Le CP, Karnezis T, Achen MG, Stacker SA, Sloan EK.

Best Pract Res Clin Anaesthesiol. 2013 Dec;27(4):409-25. doi: 10.1016/j.bpa.2013.10.008. Epub 2013 Oct 15. Review.


Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis.

Powell ND, Sloan EK, Bailey MT, Arevalo JM, Miller GE, Chen E, Kobor MS, Reader BF, Sheridan JF, Cole SW.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16574-9. doi: 10.1073/pnas.1310655110. Epub 2013 Sep 23.


Bioluminescent orthotopic model of pancreatic cancer progression.

Chai MG, Kim-Fuchs C, Angst E, Sloan EK.

J Vis Exp. 2013 Jun 28;(76). doi: 10.3791/50395.


PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases.

Kaminskas LM, Ascher DB, McLeod VM, Herold MJ, Le CP, Sloan EK, Porter CJ.

J Control Release. 2013 Jun 10;168(2):200-8. doi: 10.1016/j.jconrel.2013.03.006. Epub 2013 Mar 15.


Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche.

Sceneay J, Chow MT, Chen A, Halse HM, Wong CS, Andrews DM, Sloan EK, Parker BS, Bowtell DD, Smyth MJ, Möller A.

Cancer Res. 2012 Aug 15;72(16):3906-11. doi: 10.1158/0008-5472.CAN-11-3873. Epub 2012 Jul 2.


VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium.

Karnezis T, Shayan R, Caesar C, Roufail S, Harris NC, Ardipradja K, Zhang YF, Williams SP, Farnsworth RH, Chai MG, Rupasinghe TW, Tull DL, Baldwin ME, Sloan EK, Fox SB, Achen MG, Stacker SA.

Cancer Cell. 2012 Feb 14;21(2):181-95. doi: 10.1016/j.ccr.2011.12.026.


Chronic stress enhances progression of acute lymphoblastic leukemia via β-adrenergic signaling.

Lamkin DM, Sloan EK, Patel AJ, Chiang BS, Pimentel MA, Ma JC, Arevalo JM, Morizono K, Cole SW.

Brain Behav Immun. 2012 May;26(4):635-41. doi: 10.1016/j.bbi.2012.01.013. Epub 2012 Jan 25.


Modulation of protein tyrosine phosphorylation in gastric mucosa during re-epithelization processes.

Bogdanova OV, Kot LI, Lavrova KV, Bogdanov VB, Sloan EK, Beregova TV, Ostapchenko LI.

World J Biol Chem. 2010 Nov 26;1(11):338-47. doi: 10.4331/wjbc.v1.i11.338.


Health-related quality of life in non-small-cell lung cancer: an update of a systematic review on methodologic issues in randomized controlled trials.

Claassens L, van Meerbeeck J, Coens C, Quinten C, Ghislain I, Sloan EK, Wang XS, Velikova G, Bottomley A.

J Clin Oncol. 2011 May 20;29(15):2104-20. doi: 10.1200/JCO.2010.32.3683. Epub 2011 Apr 4. Review.


The sympathetic nervous system induces a metastatic switch in primary breast cancer.

Sloan EK, Priceman SJ, Cox BF, Yu S, Pimentel MA, Tangkanangnukul V, Arevalo JM, Morizono K, Karanikolas BD, Wu L, Sood AK, Cole SW.

Cancer Res. 2010 Sep 15;70(18):7042-52. doi: 10.1158/0008-5472.CAN-10-0522. Epub 2010 Sep 7.


Computational identification of gene-social environment interaction at the human IL6 locus.

Cole SW, Arevalo JM, Takahashi R, Sloan EK, Lutgendorf SK, Sood AK, Sheridan JF, Seeman TE.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5681-6. doi: 10.1073/pnas.0911515107. Epub 2010 Feb 22.


Stromal cell expression of caveolin-1 predicts outcome in breast cancer.

Sloan EK, Ciocca DR, Pouliot N, Natoli A, Restall C, Henderson MA, Fanelli MA, Cuello-Carrión FD, Gago FE, Anderson RL.

Am J Pathol. 2009 Jun;174(6):2035-43. doi: 10.2353/ajpath.2009.080924. Epub 2009 May 1.


To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers.

O'Connor MF, Bower JE, Cho HJ, Creswell JD, Dimitrov S, Hamby ME, Hoyt MA, Martin JL, Robles TF, Sloan EK, Thomas KS, Irwin MR.

Brain Behav Immun. 2009 Oct;23(7):887-97. doi: 10.1016/j.bbi.2009.04.005. Epub 2009 Apr 21.


Social temperament and lymph node innervation.

Sloan EK, Capitanio JP, Tarara RP, Cole SW.

Brain Behav Immun. 2008 Jul;22(5):717-26. Epub 2007 Dec 18.


SIV infection decreases sympathetic innervation of primate lymph nodes: the role of neurotrophins.

Sloan EK, Nguyen CT, Cox BF, Tarara RP, Capitanio JP, Cole SW.

Brain Behav Immun. 2008 Feb;22(2):185-94. Epub 2007 Sep 17.


Social stress enhances sympathetic innervation of primate lymph nodes: mechanisms and implications for viral pathogenesis.

Sloan EK, Capitanio JP, Tarara RP, Mendoza SP, Mason WA, Cole SW.

J Neurosci. 2007 Aug 15;27(33):8857-65.


Stress-induced remodeling of lymphoid innervation.

Sloan EK, Capitanio JP, Cole SW.

Brain Behav Immun. 2008 Jan;22(1):15-21. Epub 2007 Aug 13. Review.


Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone.

Sloan EK, Pouliot N, Stanley KL, Chia J, Moseley JM, Hards DK, Anderson RL.

Breast Cancer Res. 2006;8(2):R20. Epub 2006 Apr 11.


Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix.

Eckhardt BL, Parker BS, van Laar RK, Restall CM, Natoli AL, Tavaria MD, Stanley KL, Sloan EK, Moseley JM, Anderson RL.

Mol Cancer Res. 2005 Jan;3(1):1-13.


Caveolin-1 inhibits breast cancer growth and metastasis.

Sloan EK, Stanley KL, Anderson RL.

Oncogene. 2004 Oct 14;23(47):7893-7.


Genes involved in breast cancer metastasis to bone.

Sloan EK, Anderson RL.

Cell Mol Life Sci. 2002 Sep;59(9):1491-502. Review.


The role of CD45 and CD45-associated molecules in T cell activation.

Altin JG, Sloan EK.

Immunol Cell Biol. 1997 Oct;75(5):430-45. Review.


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