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Items: 1 to 50 of 330

1.

A randomized controlled laboratory study on the long-term effects of methylphenidate on cardiovascular function and structure in rhesus monkeys.

Wilkinson JD, Callicott R, Salminen WF, Sandhu SK, Greenhaw J, Paredes A, Davis K, Jones Y, Paule MG, Slikker W Jr, Rusconi PG, Czachor J, Bodien A, Westphal JA, Dauphin DD, Lipshultz SE.

Pediatr Res. 2019 Feb;85(3):398-404. doi: 10.1038/s41390-018-0256-9. Epub 2018 Dec 17.

PMID:
30555154
2.

Electron microscopy techniques employed to explore mitochondrial defects in the developing rat brain following ketamine treatment.

Eustaquio T, Wang C, Dugard CK, George NI, Liu F, Slikker W Jr, Paule MG, Howard PC, Paredes AM.

Exp Cell Res. 2018 Dec 15;373(1-2):164-170. doi: 10.1016/j.yexcr.2018.10.009. Epub 2018 Oct 18.

3.

Lipidomics reveals a systemic energy deficient state that precedes neurotoxicity in neonatal monkeys after sevoflurane exposure.

Wang C, Liu F, Frisch-Daiello JL, Martin S, Patterson TA, Gu Q, Liu S, Paule MG, Hanig JP, Slikker W Jr, Crawford PA, Wang C, Han X.

Anal Chim Acta. 2018 Dec 11;1037:87-96. doi: 10.1016/j.aca.2017.11.052. Epub 2017 Nov 30.

PMID:
30292318
4.

Lipidomics Reveals Changes in Metabolism, Indicative of Anesthetic-Induced Neurotoxicity in Developing Brains.

Wang C, Wang C, Liu F, Rainosek S, Patterson TA, Slikker W Jr, Han X.

Chem Res Toxicol. 2018 Sep 17;31(9):825-835. doi: 10.1021/acs.chemrestox.8b00186. Epub 2018 Sep 4.

PMID:
30132657
5.

Emerging technologies for food and drug safety.

Slikker W Jr, de Souza Lima TA, Archella D, de Silva JB Junior, Barton-Maclaren T, Bo L, Buvinich D, Chaudhry Q, Chuan P, Deluyker H, Domselaar G, Freitas M, Hardy B, Eichler HG, Hugas M, Lee K, Liao CD, Loo LH, Okuda H, Orisakwe OE, Patri A, Sactitono C, Shi L, Silva P, Sistare F, Thakkar S, Tong W, Valdez ML, Whelan M, Zhao-Wong A.

Regul Toxicol Pharmacol. 2018 Oct;98:115-128. doi: 10.1016/j.yrtph.2018.07.013. Epub 2018 Jul 23.

6.

Lipid profiling as an effective approach for identifying biomarkers/adverse events associated with pediatric anesthesia.

Wang C, Han X, Liu F, Patterson TA, Hanig JP, Paule MG, Slikker W Jr.

Toxicol Appl Pharmacol. 2018 Sep 1;354:191-195. doi: 10.1016/j.taap.2018.03.017. Epub 2018 Mar 15. Review.

PMID:
29550513
7.

Characterization of uniaxial high-speed stretch as an in vitro model of mild traumatic brain injury on the blood-brain barrier.

Rosas-Hernandez H, Cuevas E, Escudero-Lourdes C, Lantz SM, Sturdivant NM, Imam SZ, Sarkar S, Slikker W Jr, Paule MG, Balachandran K, Ali SF.

Neurosci Lett. 2018 Apr 13;672:123-129. doi: 10.1016/j.neulet.2018.02.019. Epub 2018 Feb 16.

PMID:
29458086
8.

Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study.

Imam SZ, He Z, Cuevas E, Rosas-Hernandez H, Lantz SM, Sarkar S, Raymick J, Robinson B, Hanig JP, Herr D, MacMillan D, Smith A, Liachenko S, Ferguson S, O'Callaghan J, Miller D, Somps C, Pardo ID, Slikker W Jr, B Pierson J, Roberts R, Gong B, Tong W, Aschner M, J Kallman M, Calligaro D, Paule MG.

Exp Biol Med (Maywood). 2018 Feb;243(3):228-236. doi: 10.1177/1535370217739859. Epub 2017 Nov 6.

9.

Biomarkers and their impact on precision medicine.

Slikker W Jr.

Exp Biol Med (Maywood). 2018 Feb;243(3):211-212. doi: 10.1177/1535370217733426. Epub 2017 Sep 19. No abstract available.

10.

Characterization of Biaxial Stretch as an In Vitro Model of Traumatic Brain Injury to the Blood-Brain Barrier.

Rosas-Hernandez H, Cuevas E, Escudero-Lourdes C, Lantz SM, Gomez-Crisostomo NP, Sturdivant NM, Balachandran K, Imam SZ, Slikker W Jr, Paule MG, Ali SF.

Mol Neurobiol. 2018 Jan;55(1):258-266. doi: 10.1007/s12035-017-0738-5.

PMID:
28842857
11.

Programming microphysiological systems for children's health protection.

Knudsen TB, Klieforth B, Slikker W Jr.

Exp Biol Med (Maywood). 2017 Oct;242(16):1586-1592. doi: 10.1177/1535370217717697. Epub 2017 Jun 28.

12.

Commentary.

Slikker W Jr.

Exp Biol Med (Maywood). 2017 Jun;242(12):1213. doi: 10.1177/1535370217714404. No abstract available.

13.

Minimally invasive biomarkers of general anesthetic-induced developmental neurotoxicity.

Zhang X, Liu F, Slikker W Jr, Wang C, Paule MG.

Neurotoxicol Teratol. 2017 Mar - Apr;60:95-101. doi: 10.1016/j.ntt.2016.10.007. Epub 2016 Oct 23. Review.

PMID:
27784630
14.

Potential Reuse of Oncology Drugs in the Treatment of Rare Diseases.

Liu Z, Fang H, Slikker W, Tong W.

Trends Pharmacol Sci. 2016 Oct;37(10):843-857. doi: 10.1016/j.tips.2016.06.010. Epub 2016 Jul 22. Review.

PMID:
27461952
15.

MicroPET/CT assessment of FDG uptake in brain after long-term methylphenidate treatment in nonhuman primates.

Zhang X, Newport GD, Callicott R, Liu S, Thompson J, Berridge MS, Apana SM, Slikker W Jr, Wang C, Paule MG.

Neurotoxicol Teratol. 2016 Jul-Aug;56:68-74. doi: 10.1016/j.ntt.2016.06.005. Epub 2016 Jun 12.

PMID:
27307090
16.

Regulatory bioinformatics for food and drug safety.

Healy MJ, Tong W, Ostroff S, Eichler HG, Patak A, Neuspiel M, Deluyker H, Slikker W Jr.

Regul Toxicol Pharmacol. 2016 Oct;80:342-7. doi: 10.1016/j.yrtph.2016.05.021. Epub 2016 May 18.

17.

In Vivo Monitoring of Sevoflurane-induced Adverse Effects in Neonatal Nonhuman Primates Using Small-animal Positron Emission Tomography.

Zhang X, Liu S, Newport GD, Paule MG, Callicott R, Thompson J, Liu F, Patterson TA, Berridge MS, Apana SM, Brown CC, Maisha MP, Hanig JP, Slikker W Jr, Wang C.

Anesthesiology. 2016 Jul;125(1):133-46. doi: 10.1097/ALN.0000000000001154.

PMID:
27183169
18.

Relationship between ketamine-induced developmental neurotoxicity and NMDA receptor-mediated calcium influx in neural stem cell-derived neurons.

Wang C, Liu F, Patterson TA, Paule MG, Slikker W Jr.

Neurotoxicology. 2017 May;60:254-259. doi: 10.1016/j.neuro.2016.04.015. Epub 2016 Apr 27. Review.

PMID:
27132109
19.

Comparing Morbidities of Bone Graft Harvesting from the Olecranon Process and the Distal Radius.

Micev AJ, Kalainov DM, Slikker W 3rd, Ma M, Richer RJ, Cohen MS.

Plast Reconstr Surg Glob Open. 2016 Feb 19;4(2):e623. doi: 10.1097/GOX.0000000000000617. eCollection 2016 Feb.

20.

Arthroscopic-Assisted Outside-In Repair of Triangular Fibrocartilage Complex Tears.

Frank RM, Slikker W, Al-Shihabi L, Wysocki RW.

Arthrosc Tech. 2015 Oct 21;4(5):e577-81. doi: 10.1016/j.eats.2015.06.002. eCollection 2015 Oct.

21.

Clinical Outcomes of the Flexor Carpi Ulnaris Turnover Flap for Posterior Elbow Soft Tissue Defects.

Bayne CO, Slikker W 3rd, Ma J, Ruch DS, Leversedge FJ, Cohen MS, Wysocki RW.

J Hand Surg Am. 2015 Dec;40(12):2358-63. doi: 10.1016/j.jhsa.2015.09.004.

PMID:
26612633
22.

Translational Biomarkers of Neurotoxicity: A Health and Environmental Sciences Institute Perspective on the Way Forward.

Roberts RA, Aschner M, Calligaro D, Guilarte TR, Hanig JP, Herr DW, Hudzik TJ, Jeromin A, Kallman MJ, Liachenko S, Lynch JJ 3rd, Miller DB, Moser VC, O'Callaghan JP, Slikker W Jr, Paule MG.

Toxicol Sci. 2015 Dec;148(2):332-40. doi: 10.1093/toxsci/kfv188. Review.

23.

Advancing translation of biomarkers into regulatory science.

Hong H, Slikker W Jr.

Biomark Med. 2015;9(11):1043-6. doi: 10.2217/bmm.15.104. No abstract available.

24.

Potential Adverse Effects of Prolonged Sevoflurane Exposure on Developing Monkey Brain: From Abnormal Lipid Metabolism to Neuronal Damage.

Liu F, Rainosek SW, Frisch-Daiello JL, Patterson TA, Paule MG, Slikker W Jr, Wang C, Han X.

Toxicol Sci. 2015 Oct;147(2):562-72. doi: 10.1093/toxsci/kfv150. Epub 2015 Jul 23.

25.

Total Wrist Fusion Using an Intramedullary Rod Technique With Proximal Row Carpectomy.

Frank JM, Slikker W 3rd, Al-Shihabi L, Saltzman BM, Fernandez JJ.

Tech Hand Up Extrem Surg. 2015 Sep;19(3):133-6. doi: 10.1097/BTH.0000000000000093.

PMID:
26197156
26.

Ketamine-Induced Toxicity in Neurons Differentiated from Neural Stem Cells.

Slikker W Jr, Liu F, Rainosek SW, Patterson TA, Sadovova N, Hanig JP, Paule MG, Wang C.

Mol Neurobiol. 2015 Oct;52(2):959-69. doi: 10.1007/s12035-015-9248-5. Epub 2015 Jun 9.

PMID:
26055230
27.

Effects of silver nanoparticles on human and rat embryonic neural stem cells.

Liu F, Mahmood M, Xu Y, Watanabe F, Biris AS, Hansen DK, Inselman A, Casciano D, Patterson TA, Paule MG, Slikker W Jr, Wang C.

Front Neurosci. 2015 Apr 8;9:115. doi: 10.3389/fnins.2015.00115. eCollection 2015.

28.

Genomics in the land of regulatory science.

Tong W, Ostroff S, Blais B, Silva P, Dubuc M, Healy M, Slikker W.

Regul Toxicol Pharmacol. 2015 Jun;72(1):102-6. doi: 10.1016/j.yrtph.2015.03.008. Epub 2015 Mar 18.

29.

Prevalence of Femoroacetabular Impingement Imaging Findings in Asymptomatic Volunteers: A Systematic Review.

Frank JM, Harris JD, Erickson BJ, Slikker W 3rd, Bush-Joseph CA, Salata MJ, Nho SJ.

Arthroscopy. 2015 Jun;31(6):1199-204. doi: 10.1016/j.arthro.2014.11.042. Epub 2015 Jan 28. Review.

PMID:
25636988
30.

Opportunities to integrate new approaches in genetic toxicology: an ILSI-HESI workshop report.

Zeiger E, Gollapudi B, Aardema MJ, Auerbach S, Boverhof D, Custer L, Dedon P, Honma M, Ishida S, Kasinski AL, Kim JH, Manjanatha MG, Marlowe J, Pfuhler S, Pogribny I, Slikker W, Stankowski LF Jr, Tanir JY, Tice R, van Benthem J, White P, Witt KL, Thybaud V.

Environ Mol Mutagen. 2015 Apr;56(3):277-85. doi: 10.1002/em.21923. Epub 2014 Dec 6.

31.

Positron Emission Tomography with [(18)F]FLT Revealed Sevoflurane-Induced Inhibition of Neural Progenitor Cell Expansion in vivo.

Liu S, Paule MG, Zhang X, Newport GD, Patterson TA, Apana SM, Berridge MS, Maisha MP, Slikker W Jr, Wang C.

Front Neurol. 2014 Nov 17;5:234. doi: 10.3389/fneur.2014.00234. eCollection 2014.

32.

Clinical outcomes of proximal row carpectomy versus four-corner arthrodesis for post-traumatic wrist arthropathy: a systematic review.

Saltzman BM, Frank JM, Slikker W, Fernandez JJ, Cohen MS, Wysocki RW.

J Hand Surg Eur Vol. 2015 Jun;40(5):450-7. doi: 10.1177/1753193414554359. Epub 2014 Oct 7. Review.

PMID:
25294736
33.

The use of MRI to assist the section selections for classical pathology assessment of neurotoxicity.

Hanig J, Paule MG, Ramu J, Schmued L, Konak T, Chigurupati S, Slikker W Jr, Sarkar S, Liachenko S.

Regul Toxicol Pharmacol. 2014 Dec;70(3):641-7. doi: 10.1016/j.yrtph.2014.09.010. Epub 2014 Sep 28.

PMID:
25265367
34.

Quantification and correlation of hip capsular volume to demographic and radiographic predictors.

Frank JM, Lee S, McCormick FM, Jordan M, Austell B, Slikker W, Salata MJ, Nho SJ.

Knee Surg Sports Traumatol Arthrosc. 2016 Jun;24(6):2009-15. doi: 10.1007/s00167-014-3275-z. Epub 2014 Sep 14.

PMID:
25218574
35.

Development of a physiologically based model to describe the pharmacokinetics of methylphenidate in juvenile and adult humans and nonhuman primates.

Yang X, Morris SM, Gearhart JM, Ruark CD, Paule MG, Slikker W Jr, Mattison DR, Vitiello B, Twaddle NC, Doerge DR, Young JF, Fisher JW.

PLoS One. 2014 Sep 3;9(9):e106101. doi: 10.1371/journal.pone.0106101. eCollection 2014.

36.

Global Summit on Regulatory Science 2013.

Howard PC, Tong W, Weichold F, Healy M, Slikker W.

Regul Toxicol Pharmacol. 2014 Dec;70(3):728-32. doi: 10.1016/j.yrtph.2014.08.004. Epub 2014 Aug 13.

PMID:
25128336
37.

Author reply: reverse total shoulder for acute proximal humeral fracture: comparison to open reduction-internal fixation and hemiarthroplasty.

Chalmers PN, Slikker W 3rd, Mall NA, Gupta AK, Rahman Z, Enriquez D, Nicholson GP.

J Shoulder Elbow Surg. 2014 Sep;23(9):e222. doi: 10.1016/j.jse.2014.05.014. Epub 2014 Jul 24. No abstract available.

PMID:
25066822
38.

Of human-on-a-chip and humans: considerations for creating and using microphysiological systems.

Slikker W Jr.

Exp Biol Med (Maywood). 2014 Sep;239(9):1078-9. doi: 10.1177/1535370214537754. Epub 2014 Jul 8. No abstract available.

PMID:
25005165
39.

Protective effect of acetyl-L-carnitine on propofol-induced toxicity in embryonic neural stem cells.

Liu F, Rainosek SW, Sadovova N, Fogle CM, Patterson TA, Hanig JP, Paule MG, Slikker W Jr, Wang C.

Neurotoxicology. 2014 May;42:49-57. doi: 10.1016/j.neuro.2014.03.011. Epub 2014 Apr 2.

PMID:
24704589
40.

Porcine brain microvessel endothelial cells show pro-inflammatory response to the size and composition of metallic nanoparticles.

Trickler WJ, Lantz-McPeak SM, Robinson BL, Paule MG, Slikker W Jr, Biris AS, Schlager JJ, Hussain SM, Kanungo J, Gonzalez C, Ali SF.

Drug Metab Rev. 2014 May;46(2):224-31. doi: 10.3109/03602532.2013.873450. Epub 2013 Dec 31. Review.

41.

Reverse total shoulder arthroplasty for acute proximal humeral fracture: comparison to open reduction-internal fixation and hemiarthroplasty.

Chalmers PN, Slikker W 3rd, Mall NA, Gupta AK, Rahman Z, Enriquez D, Nicholson GP.

J Shoulder Elbow Surg. 2014 Feb;23(2):197-204. doi: 10.1016/j.jse.2013.07.044. Epub 2013 Sep 27.

PMID:
24076000
42.

Pathways of neurotoxicity and innovative neuroprotective strategies. Preface.

Patterson TA, Wood WG, Andrews RJ, Slikker W Jr.

Mol Neurobiol. 2013 Oct;48(2):271-3. doi: 10.1007/s12035-013-8513-8. Epub 2013 Jul 26. No abstract available.

PMID:
23884619
43.

Routine complete capsular closure during hip arthroscopy.

Harris JD, Slikker W 3rd, Gupta AK, McCormick FM, Nho SJ.

Arthrosc Tech. 2013 Mar 17;2(2):e89-94. doi: 10.1016/j.eats.2012.11.007. Print 2013 May.

44.

Evidence of capsular defect following hip arthroscopy.

McCormick F, Slikker W 3rd, Harris JD, Gupta AK, Abrams GD, Frank J, Bach BR Jr, Nho SJ.

Knee Surg Sports Traumatol Arthrosc. 2014 Apr;22(4):902-5. doi: 10.1007/s00167-013-2591-z. Epub 2013 Jul 13.

PMID:
23851921
45.

Utilization of neural stem cell-derived models to study anesthesia-related toxicity and preventative approaches.

Wang C, Liu F, Patterson TA, Paule MG, Slikker W Jr.

Mol Neurobiol. 2013 Oct;48(2):302-7. doi: 10.1007/s12035-013-8501-z. Epub 2013 Jul 12. Review.

PMID:
23846129
46.

The use of double-loaded suture anchors for labral repair and capsular repair during hip arthroscopy.

Slikker W 3rd, Van Thiel GS, Chahal J, Nho SJ.

Arthrosc Tech. 2012 Nov 2;1(2):e213-7. doi: 10.1016/j.eats.2012.08.002. Print 2012 Dec.

47.

Neuroprotective efficacy of a new brain-penetrating C-Abl inhibitor in a murine Parkinson's disease model.

Imam SZ, Trickler W, Kimura S, Binienda ZK, Paule MG, Slikker W Jr, Li S, Clark RA, Ali SF.

PLoS One. 2013 May 31;8(5):e65129. doi: 10.1371/journal.pone.0065129. Print 2013.

48.

Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.

Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW, Ma D, Orser BA, Planel E, Slikker W Jr, Soriano SG, Stratmann G, Vutskits L, Xie Z, Hemmings HC Jr.

Br J Anaesth. 2013 Aug;111(2):143-51. doi: 10.1093/bja/aet177. Epub 2013 May 30.

49.

Preclinical assessment of ketamine.

Wang C, Liu F, Patterson TA, Paule MG, Slikker W Jr.

CNS Neurosci Ther. 2013 Jun;19(6):448-53. doi: 10.1111/cns.12079. Epub 2013 Mar 6. Review.

PMID:
23462308
50.

Application of microPET imaging approaches in the study of pediatric anesthetic-induced neuronal toxicity.

Zhang X, Paule MG, Wang C, Slikker W Jr.

J Appl Toxicol. 2013 Sep;33(9):861-8. doi: 10.1002/jat.2857. Epub 2013 Feb 11. Review.

PMID:
23400798

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