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Items: 7

1.

Haplosaurus computes protein haplotypes for use in precision drug design.

Spooner W, McLaren W, Slidel T, Finch DK, Butler R, Campbell J, Eghobamien L, Rider D, Kiefer CM, Robinson MJ, Hardman C, Cunningham F, Vaughan T, Flicek P, Huntington CC.

Nat Commun. 2018 Oct 8;9(1):4128. doi: 10.1038/s41467-018-06542-1.

2.

A Framework for Multi-Omic Prediction of Treatment Response to Biologic Therapy for Psoriasis.

Foulkes AC, Watson DS, Carr DF, Kenny JG, Slidel T, Parslew R, Pirmohamed M; PSORT Consortium, Anders S, Reynolds NJ, Griffiths CEM, Warren RB, Barnes MR.

J Invest Dermatol. 2019 Jan;139(1):100-107. doi: 10.1016/j.jid.2018.04.041. Epub 2018 Jul 17.

PMID:
30030151
3.

Engineering the expression of an anti-interleukin-13 antibody through rational design and mutagenesis.

Popovic B, Gibson S, Senussi T, Carmen S, Kidd S, Slidel T, Strickland I, Jianqing X, Spooner J, Lewis A, Hudson N, Mackenzie L, Keen J, Kemp B, Hardman C, Hatton D, Wilkinson T, Vaughan T, Lowe D.

Protein Eng Des Sel. 2017 Apr 1;30(4):303-311. doi: 10.1093/protein/gzx001.

PMID:
28130326
4.

Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893.

Tabor DE, Yu L, Mok H, Tkaczyk C, Sellman BR, Wu Y, Oganesyan V, Slidel T, Jafri H, McCarthy M, Bradford P, Esser MT.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5312-21. doi: 10.1128/AAC.00357-16. Print 2016 Sep.

5.

Predicting the expression of recombinant monoclonal antibodies in Chinese hamster ovary cells based on sequence features of the CDR3 domain.

Pybus LP, James DC, Dean G, Slidel T, Hardman C, Smith A, Daramola O, Field R.

Biotechnol Prog. 2014 Jan-Feb;30(1):188-97. doi: 10.1002/btpr.1839. Epub 2013 Dec 6.

PMID:
24311306
6.

Recognizing the fold of a protein structure.

Harrison A, Pearl F, Sillitoe I, Slidel T, Mott R, Thornton J, Orengo C.

Bioinformatics. 2003 Sep 22;19(14):1748-59.

PMID:
14512345
7.

Protein structural topology: Automated analysis and diagrammatic representation.

Westhead DR, Slidel TW, Flores TP, Thornton JM.

Protein Sci. 1999 Apr;8(4):897-904.

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