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Items: 1 to 50 of 109

1.

Prothrombotic activity of cytokine-activated endothelial cells and shear-activated platelets in the setting of ventricular assist device support.

Apostoli A, Bianchi V, Bono N, Dimasi A, Ammann KR, Moiia YR, Montisci A, Sheriff J, Bluestein D, Fiore GB, Pappalardo F, Candiani G, Redaelli A, Slepian MJ, Consolo F.

J Heart Lung Transplant. 2019 Jun;38(6):658-667. doi: 10.1016/j.healun.2019.02.009. Epub 2019 Feb 18.

PMID:
30846234
2.

In Vitro Durability and Stability Testing of a Novel Polymeric Transcatheter Aortic Valve.

Rotman OM, Kovarovic B, Bianchi M, Slepian MJ, Bluestein D.

ASAIO J. 2019 Apr 2. doi: 10.1097/MAT.0000000000000980. [Epub ahead of print]

PMID:
30845067
3.

Device Thrombogenicity Emulation: An In Silico Predictor of In Vitro and In Vivo Ventricular Assist Device Thrombogenicity.

Chiu WC, Tran PL, Khalpey Z, Lee E, Woo YR, Slepian MJ, Bluestein D.

Sci Rep. 2019 Feb 27;9(1):2946. doi: 10.1038/s41598-019-39897-6.

4.

Surface Modification of Electrospun Scaffolds for Endothelialization of Tissue-Engineered Vascular Grafts Using Human Cord Blood-Derived Endothelial Cells.

Ardila DC, Liou JJ, Maestas D, Slepian MJ, Badowski M, Wagner WR, Harris D, Vande Geest JP.

J Clin Med. 2019 Feb 4;8(2). pii: E185. doi: 10.3390/jcm8020185.

5.

Migration versus proliferation as contributor to in vitro wound healing of vascular endothelial and smooth muscle cells.

Ammann KR, DeCook KJ, Li M, Slepian MJ.

Exp Cell Res. 2019 Mar 1;376(1):58-66. doi: 10.1016/j.yexcr.2019.01.011. Epub 2019 Jan 17.

PMID:
30660619
6.

Blood damage in Left Ventricular Assist Devices: Pump thrombosis or system thrombosis?

Selmi M, Chiu WC, Chivukula VK, Melisurgo G, Beckman JA, Mahr C, Aliseda A, Votta E, Redaelli A, Slepian MJ, Bluestein D, Pappalardo F, Consolo F.

Int J Artif Organs. 2019 Mar;42(3):113-124. doi: 10.1177/0391398818806162. Epub 2018 Oct 24. Review.

PMID:
30354870
7.

Relation between blood pressure and pulse wave velocity for human arteries.

Ma Y, Choi J, Hourlier-Fargette A, Xue Y, Chung HU, Lee JY, Wang X, Xie Z, Kang D, Wang H, Han S, Kang SK, Kang Y, Yu X, Slepian MJ, Raj MS, Model JB, Feng X, Ghaffari R, Rogers JA, Huang Y.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11144-11149. doi: 10.1073/pnas.1814392115. Epub 2018 Oct 15.

8.

Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Applications: In Vitro Hemodynamic Study.

Rotman OM, Kovarovic B, Chiu WC, Bianchi M, Marom G, Slepian MJ, Bluestein D.

Ann Biomed Eng. 2019 Jan;47(1):113-125. doi: 10.1007/s10439-018-02119-7. Epub 2018 Sep 7.

9.

Design Effect of Metallic (Durable) and Polymeric (Resorbable) Stents on Blood Flow and Platelet Activation.

Marom G, Eswaran SK, Rapoza RJ, Hossainy SFA, Slepian MJ, Bluestein D.

Artif Organs. 2018 Dec;42(12):1148-1156. doi: 10.1111/aor.13276. Epub 2018 Sep 5.

PMID:
30187513
10.

LVAD Pulsatility Assesses Cardiac Contractility: In Vitro Model Utilizing the Total Artificial Heart and Mock Circulation.

Mikail P, Crosby JR, Slepian MJ, Smith R, Khalpey Z.

ASAIO J. 2018 Aug 2. doi: 10.1097/MAT.0000000000000861. [Epub ahead of print]

PMID:
30074963
11.

Comparative Fluid-Structure Interaction Analysis of Polymeric Transcatheter and Surgical Aortic Valves' Hemodynamics and Structural Mechanics.

Ghosh R, Marom G, Rotman O, Slepian MJ, Prabhakar S, Horner M, Bluestein D.

J Biomech Eng. 2018 Jun 25. doi: 10.1115/1.4040600. [Epub ahead of print]

PMID:
30029207
12.

Shear-Mediated Platelet Activation Enhances Thrombotic Complications in Patients With LVADs and Is Reversed After Heart Transplantation.

Consolo F, Sferrazza G, Motolone G, Pieri M, De Bonis M, Zangrillo A, Redaelli A, Slepian MJ, Pappalardo F.

ASAIO J. 2019 May/Jun;65(4):e33-e35. doi: 10.1097/MAT.0000000000000842.

PMID:
29952802
13.

Microfluidic flow-based platforms for induction and analysis of dynamic shear-mediated platelet activation-Initial validation versus the standardized hemodynamic shearing device.

Dimasi A, Roka-Moiia Y, Consolo F, Rasponi M, Fiore GB, Slepian MJ, Redaelli A.

Biomicrofluidics. 2018 May 22;12(4):042208. doi: 10.1063/1.5024500. eCollection 2018 Jul.

14.

Stretchable Electronic Wearable Motion Sensors Delineate Signatures of Human Motion Tasks.

Garlant JA, Ammann KR, Slepian MJ.

ASAIO J. 2018 May/Jun;64(3):351-359. doi: 10.1097/MAT.0000000000000784.

15.

Routine clinical anti-platelet agents have limited efficacy in modulating hypershear-mediated platelet activation associated with mechanical circulatory support.

Valerio L, Sheriff J, Tran PL, Brengle W, Redaelli A, Fiore GB, Pappalardo F, Bluestein D, Slepian MJ.

Thromb Res. 2018 Mar;163:162-171. doi: 10.1016/j.thromres.2017.12.001. Epub 2017 Dec 5.

16.

Which Antiplatelet Therapy in Patients With Left Ventricular Assist Device and Aspirin Allergy?

Consolo F, Pozzi L, Sferrazza G, Della Valle P, D'Angelo A, Slepian MJ, Pappalardo F.

Ann Thorac Surg. 2018 Feb;105(2):e47-e49. doi: 10.1016/j.athoracsur.2017.09.022.

PMID:
29362190
17.

Platelet activation is a preoperative risk factor for the development of thromboembolic complications in patients with continuous-flow left ventricular assist device.

Consolo F, Sferrazza G, Motolone G, Contri R, Valerio L, Lembo R, Pozzi L, Della Valle P, De Bonis M, Zangrillo A, Fiore GB, Redaelli A, Slepian MJ, Pappalardo F.

Eur J Heart Fail. 2018 Apr;20(4):792-800. doi: 10.1002/ejhf.1113. Epub 2017 Dec 28.

18.

Sildenafil Is Associated With Reduced Device Thrombosis and Ischemic Stroke Despite Low-Level Hemolysis on Heart Mate II Support.

Saeed O, Rangasamy S, Selevany I, Madan S, Fertel J, Eisenberg R, Aljoudi M, Patel SR, Shin J, Sims DB, Reyes Gil M, Goldstein DJ, Slepian MJ, Billett HH, Jorde UP.

Circ Heart Fail. 2017 Nov;10(11). pii: e004222. doi: 10.1161/CIRCHEARTFAILURE.117.004222.

PMID:
29092891
19.

16S rRNA gene sequencing on a benchtop sequencer: accuracy for identification of clinically important bacteria.

Watts GS, Youens-Clark K, Slepian MJ, Wolk DM, Oshiro MM, Metzger GS, Dhingra D, Cranmer LD, Hurwitz BL.

J Appl Microbiol. 2017 Dec;123(6):1584-1596. doi: 10.1111/jam.13590. Epub 2017 Nov 7.

20.

Remote Ischemic ConditioningPromising Potential in Wound Repair in Diabetes?

Boghossian JA, Joseph B, Slepian MJ, Armstrong DG.

J Am Podiatr Med Assoc. 2017 Jul;107(4):313-317. doi: 10.7547/15-172. Review.

PMID:
28880591
21.

Microfludic platforms for the evaluation of anti-platelet agent efficacy under hyper-shear conditions associated with ventricular assist devices.

Dimasi A, Rasponi M, Consolo F, Fiore GB, Bluestein D, Slepian MJ, Redaelli A.

Med Eng Phys. 2017 Oct;48:31-38. doi: 10.1016/j.medengphy.2017.08.005. Epub 2017 Aug 30.

22.

High Frequency Components of Hemodynamic Shear Stress Profiles are a Major Determinant of Shear-Mediated Platelet Activation in Therapeutic Blood Recirculating Devices.

Consolo F, Sheriff J, Gorla S, Magri N, Bluestein D, Pappalardo F, Slepian MJ, Fiore GB, Redaelli A.

Sci Rep. 2017 Jul 10;7(1):4994. doi: 10.1038/s41598-017-05130-5.

23.

Bifidobacterium animalis subsp. lactis 420 mitigates the pathological impact of myocardial infarction in the mouse.

Danilo CA, Constantopoulos E, McKee LA, Chen H, Regan JA, Lipovka Y, Lahtinen S, Stenman LK, Nguyen TV, Doyle KP, Slepian MJ, Khalpey ZI, Konhilas JP.

Benef Microbes. 2017 Apr 26;8(2):257-269. doi: 10.3920/BM2016.0119. Epub 2017 Apr 14.

24.

Epidermal mechano-acoustic sensing electronics for cardiovascular diagnostics and human-machine interfaces.

Liu Y, Norton JJ, Qazi R, Zou Z, Ammann KR, Liu H, Yan L, Tran PL, Jang KI, Lee JW, Zhang D, Kilian KA, Jung SH, Bretl T, Xiao J, Slepian MJ, Huang Y, Jeong JW, Rogers JA.

Sci Adv. 2016 Nov 16;2(11):e1601185. doi: 10.1126/sciadv.1601185. eCollection 2016 Nov.

25.

A Physical Heart Failure Simulation System Utilizing the Total Artificial Heart and Modified Donovan Mock Circulation.

Crosby JR, DeCook KJ, Tran PL, Betterton E, Smith RG, Larson DF, Khalpey ZI, Burkhoff D, Slepian MJ.

Artif Organs. 2017 Jul;41(7):E52-E65. doi: 10.1111/aor.12808. Epub 2016 Dec 9.

26.

Ventricular Assist Device Implantation Configurations Impact Overall Mechanical Circulatory Support System Thrombogenic Potential.

Chiu WC, Alemu Y, McLarty AJ, Einav S, Slepian MJ, Bluestein D.

ASAIO J. 2017 May/Jun;63(3):285-292. doi: 10.1097/MAT.0000000000000488.

27.

Effect of Balloon-Expandable Transcatheter Aortic Valve Replacement Positioning: A Patient-Specific Numerical Model.

Bianchi M, Marom G, Ghosh RP, Fernandez HA, Taylor JR Jr, Slepian MJ, Bluestein D.

Artif Organs. 2016 Dec;40(12):E292-E304. doi: 10.1111/aor.12806.

28.

A multiscale biomechanical model of platelets: Correlating with in-vitro results.

Zhang P, Zhang L, Slepian MJ, Deng Y, Bluestein D.

J Biomech. 2017 Jan 4;50:26-33. doi: 10.1016/j.jbiomech.2016.11.019. Epub 2016 Nov 11.

29.

Shear-mediated platelet activation in the free flow: Perspectives on the emerging spectrum of cell mechanobiological mechanisms mediating cardiovascular implant thrombosis.

Slepian MJ, Sheriff J, Hutchinson M, Tran P, Bajaj N, Garcia JGN, Scott Saavedra S, Bluestein D.

J Biomech. 2017 Jan 4;50:20-25. doi: 10.1016/j.jbiomech.2016.11.016. Epub 2016 Nov 10.

30.

A soft, wearable microfluidic device for the capture, storage, and colorimetric sensing of sweat.

Koh A, Kang D, Xue Y, Lee S, Pielak RM, Kim J, Hwang T, Min S, Banks A, Bastien P, Manco MC, Wang L, Ammann KR, Jang KI, Won P, Han S, Ghaffari R, Paik U, Slepian MJ, Balooch G, Huang Y, Rogers JA.

Sci Transl Med. 2016 Nov 23;8(366):366ra165.

31.

Plantar Fat Grafting and Tendon Balancing for the Diabetic Foot Ulcer in Remission.

Luu CA, Larson E, Rankin TM, Pappalardo JL, Slepian MJ, Armstrong DG.

Plast Reconstr Surg Glob Open. 2016 Jul 20;4(7):e810. doi: 10.1097/GOX.0000000000000813. eCollection 2016 Jul.

32.

Reactive oxygen species-associated molecular signature predicts survival in patients with sepsis.

Bime C, Zhou T, Wang T, Slepian MJ, Garcia JG, Hecker L.

Pulm Circ. 2016 Jun;6(2):196-201. doi: 10.1086/685547.

33.

Microfluidic approaches for the assessment of blood cell trauma: a focus on thrombotic risk in mechanical circulatory support devices.

Consolo F, Dimasi A, Rasponi M, Valerio L, Pappalardo F, Bluestein D, Slepian MJ, Fiore GB, Redaelli A.

Int J Artif Organs. 2016 Jun 15;39(4):184-93. doi: 10.5301/ijao.5000485. Epub 2016 Mar 30.

PMID:
27034318
34.

Aspirin has limited ability to modulate shear-mediated platelet activation associated with elevated shear stress of ventricular assist devices.

Valerio L, Tran PL, Sheriff J, Brengle W, Ghosh R, Chiu WC, Redaelli A, Fiore GB, Pappalardo F, Bluestein D, Slepian MJ.

Thromb Res. 2016 Apr;140:110-117. doi: 10.1016/j.thromres.2016.01.026. Epub 2016 Feb 1.

35.

First North American 50 cc Total Artificial Heart Experience: Conversion from a 70 cc Total Artificial Heart.

Khalpey Z, Kazui T, Ferng AS, Connell A, Tran PL, Meyer M, Rawashdeh B, Smith RG, Sweitzer NK, Friedman M, Lick S, Slepian MJ, Copeland JG.

ASAIO J. 2016 Sep-Oct;62(5):e43-5. doi: 10.1097/MAT.0000000000000352.

PMID:
26809081
36.

Simulation of Transcatheter Aortic Valve Replacement in patient-specific aortic roots: Effect of crimping and positioning on device performance.

Bianchi M, Ghosh RP, Marom G, Slepian MJ, Bluestein D.

Conf Proc IEEE Eng Med Biol Soc. 2015;2015:282-5. doi: 10.1109/EMBC.2015.7318355.

PMID:
26736255
37.

The platelet hammer: In vitro platelet activation under repetitive hypershear.

Sheriff J, Tran PL, Hutchinson M, DeCook T, Slepian MJ, Bluestein D, Jesty J.

Conf Proc IEEE Eng Med Biol Soc. 2015;2015:262-5. doi: 10.1109/EMBC.2015.7318350.

PMID:
26736250
38.

Epidermal devices for noninvasive, precise, and continuous mapping of macrovascular and microvascular blood flow.

Webb RC, Ma Y, Krishnan S, Li Y, Yoon S, Guo X, Feng X, Shi Y, Seidel M, Cho NH, Kurniawan J, Ahad J, Sheth N, Kim J, Taylor JG 6th, Darlington T, Chang K, Huang W, Ayers J, Gruebele A, Pielak RM, Slepian MJ, Huang Y, Gorbach AM, Rogers JA.

Sci Adv. 2015 Oct 30;1(9):e1500701. doi: 10.1126/sciadv.1500701. eCollection 2015 Oct.

39.

Hemolysate-mediated platelet aggregation: an additional risk mechanism contributing to thrombosis of continuous flow ventricular assist devices.

Tran PL, Pietropaolo MG, Valerio L, Brengle W, Wong RK, Kazui T, Khalpey ZI, Redaelli A, Sheriff J, Bluestein D, Slepian MJ.

Perfusion. 2016 Jul;31(5):401-8. doi: 10.1177/0267659115615206. Epub 2015 Nov 20.

40.

Microfluidic emulation of mechanical circulatory support device shear-mediated platelet activation.

Dimasi A, Rasponi M, Sheriff J, Chiu WC, Bluestein D, Tran PL, Slepian MJ, Redaelli A.

Biomed Microdevices. 2015 Dec;17(6):117. doi: 10.1007/s10544-015-0015-1.

41.

Case Report: Disparate flow in HeartMate II patient with extensive left ventricle repair.

Tran PL, Kazui T, Perovic V, Mikail P, Lick S, Smith R, Betterton EW, Venkat R, Iwanski J, Wong RK, Slepian MJ, Khalpey Z.

Perfusion. 2016 May;31(4):349-52. doi: 10.1177/0267659115614639. Epub 2015 Nov 2.

PMID:
26531760
42.

Repetitive Hypershear Activates and Sensitizes Platelets in a Dose-Dependent Manner.

Sheriff J, Tran PL, Hutchinson M, DeCook T, Slepian MJ, Bluestein D, Jesty J.

Artif Organs. 2016 Jun;40(6):586-95. doi: 10.1111/aor.12602. Epub 2015 Nov 3.

43.

Biomechanical Comparison of Glutaraldehyde-Crosslinked Gelatin Fibrinogen Electrospun Scaffolds to Porcine Coronary Arteries.

Tamimi E, Ardila DC, Haskett DG, Doetschman T, Slepian MJ, Kellar RS, Vande Geest JP.

J Biomech Eng. 2016 Jan;138(1). doi: 10.1115/1.4031847.

44.

Collective cell migration of smooth muscle and endothelial cells: impact of injury versus non-injury stimuli.

Ammann KR, DeCook KJ, Tran PL, Merkle VM, Wong PK, Slepian MJ.

J Biol Eng. 2015 Oct 15;9:19. doi: 10.1186/s13036-015-0015-y. eCollection 2015.

45.

Physical Characterization and Platelet Interactions under Shear Flows of a Novel Thermoset Polyisobutylene-based Co-polymer.

Sheriff J, Claiborne TE, Tran PL, Kothadia R, George S, Kato YP, Pinchuk L, Slepian MJ, Bluestein D.

ACS Appl Mater Interfaces. 2015 Oct 7;7(39):22058-66. doi: 10.1021/acsami.5b07254. Epub 2015 Sep 23.

46.

Hemodynamic and thrombogenic analysis of a trileaflet polymeric valve using a fluid-structure interaction approach.

Piatti F, Sturla F, Marom G, Sheriff J, Claiborne TE, Slepian MJ, Redaelli A, Bluestein D.

J Biomech. 2015 Oct 15;48(13):3641-9. doi: 10.1016/j.jbiomech.2015.08.009. Epub 2015 Aug 21.

47.

Core-shell PVA/gelatin electrospun nanofibers promote human umbilical vein endothelial cell and smooth muscle cell proliferation and migration.

Merkle VM, Tran PL, Hutchinson M, Ammann KR, DeCook K, Wu X, Slepian MJ.

Acta Biomater. 2015 Nov;27:77-87. doi: 10.1016/j.actbio.2015.08.044. Epub 2015 Aug 28.

PMID:
26320540
48.

Cybersecurity Regulation of Wireless Devices for Performance and Assurance in the Age of "Medjacking".

Armstrong DG, Kleidermacher DN, Klonoff DC, Slepian MJ.

J Diabetes Sci Technol. 2015 Aug 27;10(2):435-8. doi: 10.1177/1932296815602100.

49.

Dielectrophoresis-Mediated Electrodeformation as a Means of Determining Individual Platelet Stiffness.

Leung SL, Lu Y, Bluestein D, Slepian MJ.

Ann Biomed Eng. 2016 Apr;44(4):903-13. doi: 10.1007/s10439-015-1383-7. Epub 2015 Jul 23.

50.

Regulation of Cardiac Autonomic Nervous System Control across Frailty Statuses: A Systematic Review.

Parvaneh S, Howe CL, Toosizadeh N, Honarvar B, Slepian MJ, Fain M, Mohler J, Najafi B.

Gerontology. 2015;62(1):3-15. doi: 10.1159/000431285. Epub 2015 Jul 3. Review.

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