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Items: 30

1.

Topical delivery of Cyclosporine A into the skin using SPACE-peptide.

Chen M, Kumar S, Anselmo AC, Gupta V, Slee DH, Muraski JA, Mitragotri S.

J Control Release. 2015 Feb 10;199:190-7. doi: 10.1016/j.jconrel.2014.11.015. Epub 2014 Dec 4.

PMID:
25481447
2.

Polycyclic aromatic hydrocarbons in road-deposited sediments, water sediments, and soils in Sydney, Australia: Comparisons of concentration distribution, sources and potential toxicity.

Nguyen TC, Loganathan P, Nguyen TV, Vigneswaran S, Kandasamy J, Slee D, Stevenson G, Naidu R.

Ecotoxicol Environ Saf. 2014 Jun;104:339-48. doi: 10.1016/j.ecoenv.2014.03.010. Epub 2014 Apr 15.

PMID:
24732030
3.

Topical delivery of siRNA into skin using SPACE-peptide carriers.

Chen M, Zakrewsky M, Gupta V, Anselmo AC, Slee DH, Muraski JA, Mitragotri S.

J Control Release. 2014 Apr 10;179:33-41. doi: 10.1016/j.jconrel.2014.01.006. Epub 2014 Jan 13.

4.

In vivo measurement, in vitro estimation and fugacity prediction of PAH bioavailability in post-remediated creosote-contaminated soil.

Juhasz AL, Weber J, Stevenson G, Slee D, Gancarz D, Rofe A, Smith E.

Sci Total Environ. 2014 Mar 1;473-474:147-54. doi: 10.1016/j.scitotenv.2013.12.031. Epub 2013 Dec 22.

PMID:
24368196
5.

Discovery of NBI-77860/GSK561679, a potent corticotropin-releasing factor (CRF1) receptor antagonist with improved pharmacokinetic properties.

Tellew JE, Lanier M, Moorjani M, Lin E, Luo Z, Slee DH, Zhang X, Hoare SR, Grigoriadis DE, St Denis Y, Di Fabio R, Di Modugno E, Saunders J, Williams JP.

Bioorg Med Chem Lett. 2010 Dec 15;20(24):7259-64. doi: 10.1016/j.bmcl.2010.10.095. Epub 2010 Oct 25.

PMID:
21074436
6.

N-[6-amino-2-(heteroaryl)pyrimidin-4-yl]acetamides as A2A receptor antagonists with improved drug like properties and in vivo efficacy.

Lanier MC, Moorjani M, Luo Z, Chen Y, Lin E, Tellew JE, Zhang X, Williams JP, Gross RS, Lechner SM, Markison S, Joswig T, Kargo W, Piercey J, Santos M, Malany S, Zhao M, Petroski R, Crespo MI, Díaz JL, Saunders J, Wen J, O'Brien Z, Jalali K, Madan A, Slee DH.

J Med Chem. 2009 Feb 12;52(3):709-17. doi: 10.1021/jm800908d.

PMID:
19140664
7.

Lead optimization of 4-acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson's disease.

Zhang X, Tellew JE, Luo Z, Moorjani M, Lin E, Lanier MC, Chen Y, Williams JP, Saunders J, Lechner SM, Markison S, Joswig T, Petroski R, Piercey J, Kargo W, Malany S, Santos M, Gross RS, Wen J, Jalali K, O'Brien Z, Stotz CE, Crespo MI, Díaz JL, Slee DH.

J Med Chem. 2008 Nov 27;51(22):7099-110. doi: 10.1021/jm800851u.

PMID:
18947224
8.

2,6-Diaryl-4-acylaminopyrimidines as potent and selective adenosine A(2A) antagonists with improved solubility and metabolic stability.

Moorjani M, Luo Z, Lin E, Vong BG, Chen Y, Zhang X, Rueter JK, Gross RS, Lanier MC, Tellew JE, Williams JP, Lechner SM, Malany S, Santos M, Crespo MI, Díaz JL, Saunders J, Slee DH.

Bioorg Med Chem Lett. 2008 Oct 15;18(20):5402-5. doi: 10.1016/j.bmcl.2008.09.048. Epub 2008 Sep 14.

PMID:
18835161
9.

Drugability of extracellular targets: discovery of small molecule drugs targeting allosteric, functional, and subunit-selective sites on GPCRs and ion channels.

Grigoriadis DE, Hoare SR, Lechner SM, Slee DH, Williams JA.

Neuropsychopharmacology. 2009 Jan;34(1):106-25. doi: 10.1038/npp.2008.149. Epub 2008 Sep 17. Review.

10.

Effects of the transient receptor potential vanilloid 1 antagonist A-425619 on body temperature and thermoregulation in the rat.

Mills C, McMackin M, Jaffe R, Yu J, Zininberg E, Slee D, Gogas K, Bradbury M.

Neuroscience. 2008 Sep 22;156(1):165-74. doi: 10.1016/j.neuroscience.2008.06.069. Epub 2008 Jul 25.

PMID:
18706981
11.

Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A2A receptor antagonists.

Zhang X, Rueter JK, Chen Y, Moorjani M, Lanier MC, Lin E, Gross RS, Tellew JE, Williams JP, Lechner SM, Markison S, Joswig T, Malany S, Santos M, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Saunders J, Slee DH.

Bioorg Med Chem Lett. 2008 Mar 15;18(6):1778-83. doi: 10.1016/j.bmcl.2008.02.032. Epub 2008 Feb 16.

PMID:
18329269
12.

2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 2. Reduction of hERG activity, observed species selectivity, and structure-activity relationships.

Slee DH, Moorjani M, Zhang X, Lin E, Lanier MC, Chen Y, Rueter JK, Lechner SM, Markison S, Malany S, Joswig T, Santos M, Gross RS, Williams JP, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Jalali K, Sai Y, Zuo Z, Yang C, Wen J, O'Brien Z, Petroski R, Saunders J.

J Med Chem. 2008 Mar 27;51(6):1730-9. doi: 10.1021/jm701187w. Epub 2008 Feb 29.

PMID:
18307293
13.

2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 1. Structure-activity relationships and optimization of heterocyclic substituents.

Slee DH, Chen Y, Zhang X, Moorjani M, Lanier MC, Lin E, Rueter JK, Williams JP, Lechner SM, Markison S, Malany S, Santos M, Gross RS, Jalali K, Sai Y, Zuo Z, Yang C, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Saunders J.

J Med Chem. 2008 Mar 27;51(6):1719-29. doi: 10.1021/jm701185v. Epub 2008 Feb 29.

PMID:
18307292
14.

2,6-Diaryl-4-phenacylaminopyrimidines as potent and selective adenosine A(2A) antagonists with reduced hERG liability.

Moorjani M, Zhang X, Chen Y, Lin E, Rueter JK, Gross RS, Lanier MC, Tellew JE, Williams JP, Lechner SM, Malany S, Santos M, Ekhlassi P, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Saunders J, Slee DH.

Bioorg Med Chem Lett. 2008 Feb 15;18(4):1269-73. doi: 10.1016/j.bmcl.2008.01.036. Epub 2008 Jan 13.

PMID:
18249540
15.

Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy.

Slee DH, Zhang X, Moorjani M, Lin E, Lanier MC, Chen Y, Rueter JK, Lechner SM, Markison S, Malany S, Joswig T, Santos M, Gross RS, Williams JP, Castro-Palomino JC, Crespo MI, Prat M, Gual S, Díaz JL, Wen J, O'Brien Z, Saunders J.

J Med Chem. 2008 Feb 14;51(3):400-6. doi: 10.1021/jm070623o. Epub 2008 Jan 12.

PMID:
18189346
16.

Selection, synthesis, and structure-activity relationship of tetrahydropyrido[4,3-d]pyrimidine-2,4-diones as human GnRH receptor antagonists.

Lanier MC, Feher M, Ashweek NJ, Loweth CJ, Rueter JK, Slee DH, Williams JP, Zhu YF, Sullivan SK, Brown MS.

Bioorg Med Chem. 2007 Aug 15;15(16):5590-603. Epub 2007 May 17.

PMID:
17561404
17.

The development of a cocktail CYP2B6, CYP2C8, and CYP3A5 inhibition assay and a preliminary assessment of utility in a drug discovery setting.

O'Donnell CJ, Grime K, Courtney P, Slee D, Riley RJ.

Drug Metab Dispos. 2007 Mar;35(3):381-5. Epub 2006 Dec 1.

PMID:
17142561
18.

The tyranny of the diagnosis code.

Slee VN, Slee D, Schmidt HJ.

N C Med J. 2005 Sep-Oct;66(5):331-7.

PMID:
16323579
19.

Identification of chlorfenvinphos toxicity in a municipal effluent in Sydney, New South Wales, Australia.

Bailey HC, Elphick JR, Krassoi R, Mulhall AM, Lovell AJ, Slee DJ.

Environ Toxicol Chem. 2005 Jul;24(7):1773-8.

PMID:
16050596
20.

Inhibition of fructose-1,6-bisphosphatase by a new class of allosteric effectors.

Choe JY, Nelson SW, Arienti KL, Axe FU, Collins TL, Jones TK, Kimmich RD, Newman MJ, Norvell K, Ripka WC, Romano SJ, Short KM, Slee DH, Fromm HJ, Honzatko RB.

J Biol Chem. 2003 Dec 19;278(51):51176-83. Epub 2003 Oct 6.

21.

Pyrrolopyrazinedione-based inhibitors of human hormone-sensitive lipase.

Slee DH, Bhat AS, Nguyen TN, Kish M, Lundeen K, Newman MJ, McConnell SJ.

J Med Chem. 2003 Mar 27;46(7):1120-2.

PMID:
12646020
22.

Targeting selectins for the treatment of respiratory diseases.

Romano SJ, Slee DH.

Curr Opin Investig Drugs. 2001 Jul;2(7):907-13. Review.

PMID:
11757789
23.

Development of potent non-carbohydrate imidazole-based small molecule selectin inhibitors with antiinflammatory activity.

Slee DH, Romano SJ, Yu J, Nguyen TN, John JK, Raheja NK, Axe FU, Jones TK, Ripka WC.

J Med Chem. 2001 Jun 21;44(13):2094-107.

PMID:
11405647
24.

[Acute hemorrhagic edema in children: excellent prognosis].

Slee DS, Lagro SW, Frenkel J.

Ned Tijdschr Geneeskd. 2001 Apr 28;145(17):830-4. Dutch.

PMID:
11370430
25.

[Fabry disease: data from four families].

Slee PH, van Boven LJ, Slee DS.

Ned Tijdschr Geneeskd. 2000 Dec 9;144(50):2412-5. Dutch.

PMID:
11145098
26.

[Following Gerard van Swieten's footsteps].

Slee DS, Slee PH.

Ned Tijdschr Geneeskd. 1996 Dec 21;140(51):2574-7. Dutch. No abstract available.

PMID:
9053752
27.

Hydroxyethylation of hemoglobin by 1-(2-chloroethyl)-1-nitrosoureas.

Bailey E, Farmer PB, Tang YS, Vangikar H, Gray A, Slee D, Ings RM, Campbell DB, McVie JG, Dubbelman R.

Chem Res Toxicol. 1991 Jul-Aug;4(4):462-6.

PMID:
1912334
28.

Proinsulin processing in electrically permeabilized rat islets of Langerhans.

Slee DJ, Jones PM, Howell SL.

J Mol Endocrinol. 1990 Dec;5(3):275-80.

PMID:
2288639
29.

Quality assurance in health care. Confidentiality of information and immunity for participants.

Southwick AF, Slee DA.

J Leg Med. 1984 Sep;5(3):343-97. Review. No abstract available.

PMID:
6389738
30.

A need to know.

Slee DM, Ryan AJ, Biancardi AE, Stauffer LW.

Phys Sportsmed. 1977 Feb;5(2):94. doi: 10.1080/00913847.1977.11710521. No abstract available.

PMID:
27398966

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