Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 1
2009 1
2010 2
2011 4
2012 5
2013 6
2014 10
2015 5
2016 7
2017 7
2018 11
2019 11
2020 13
2021 11
2022 13
2023 9
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

99 results

Results by year

Filters applied: . Clear all
Page 1
SLC17A9-PTHLH-EMT axis promotes proliferation and invasion of clear renal cell carcinoma.
Li W, Xu N, Meng X, Yuan H, Yu T, Miao Q, Yang H, Hai B, Xiao W, Zhang X. Li W, et al. iScience. 2022 Dec 9;26(1):105764. doi: 10.1016/j.isci.2022.105764. eCollection 2023 Jan 20. iScience. 2022. PMID: 36590170 Free PMC article.
The overexpression of SLC17A9 in vivo could significantly contribute to the growth of tumors. Finally, we found that SLC17A9 might be related to the drug resistance of vorinostat. Cumulatively, this study demonstrated that the SLC17A9-PTHLH-EMT axis could pro …
The overexpression of SLC17A9 in vivo could significantly contribute to the growth of tumors. Finally, we found that SLC17A9 m …
SLC17A9 as a prognostic biomarker correlated with immune infiltrates in human non-small cell lung cancer.
Gao Y, Chen Y, Liu M, Zeng D, Tan F, Wan H, Liu X, Su S, Zhang Y, Zhang Y, Ke C, Pei Z. Gao Y, et al. Am J Cancer Res. 2023 Sep 15;13(9):3963-3982. eCollection 2023. Am J Cancer Res. 2023. PMID: 37818081 Free PMC article.
Integrative bioinformatics analysis was performed to investigate the prognostic significance and underlying mechanisms of SLC17A9 in patients with NSCLC. Here, we found that SLC17A9 up-regulation was significantly correlated with overall survival in LUAD and LUSC (P …
Integrative bioinformatics analysis was performed to investigate the prognostic significance and underlying mechanisms of SLC17A9 in …
NLRP3 Inflammasome Activation Through Heart-Brain Interaction Initiates Cardiac Inflammation and Hypertrophy During Pressure Overload.
Higashikuni Y, Liu W, Numata G, Tanaka K, Fukuda D, Tanaka Y, Hirata Y, Imamura T, Takimoto E, Komuro I, Sata M. Higashikuni Y, et al. Circulation. 2023 Jan 24;147(4):338-355. doi: 10.1161/CIRCULATIONAHA.122.060860. Epub 2022 Nov 28. Circulation. 2023. PMID: 36440584
METHODS: C57BL/6 mice, knockout mouse strains for NLRP3 and P2RX7 (P2X purinoceptor 7), and adrenergic neuron-specific knockout mice for SLC17A9, a secretory vesicle protein responsible for the storage and release of ATP, were used for analysis. ...
METHODS: C57BL/6 mice, knockout mouse strains for NLRP3 and P2RX7 (P2X purinoceptor 7), and adrenergic neuron-specific knockout mice for …
High SLC17A9 expression correlates with poor survival in gastric carcinoma.
Li J, Su T, Yang L, Deng L, Zhang C, He Y. Li J, et al. Future Oncol. 2019 Dec;15(36):4155-4166. doi: 10.2217/fon-2019-0283. Epub 2019 Dec 4. Future Oncol. 2019. PMID: 31799885 Free article.
Aim: To elucidate the clinicopathological significance and prognostic value of SLC17A9 expression in gastric carcinoma (GC). Methods: SLC17A9 mRNA level and its relationship with TP53 mutation was analyzed. SLC17A9 protein expression was examined by immunohis …
Aim: To elucidate the clinicopathological significance and prognostic value of SLC17A9 expression in gastric carcinoma (GC). Methods: …
Lysosomal ATP Transporter SLC17A9 Controls Cell Viability via Regulating Cathepsin D.
Huang P, Cao Q, Xu M, Dong XP. Huang P, et al. Cells. 2022 Mar 4;11(5):887. doi: 10.3390/cells11050887. Cells. 2022. PMID: 35269509 Free PMC article.
Interestingly, Cathepsin D, a lysosomal aspartic protease, is inhibited by SLC17A9 deficiency. Heterologous expression of Cathepsin D successfully rescues lysosomal dysfunction and cell death induced by SLC17A9 deficiency. On the other hand, the activity of Cathepsi …
Interestingly, Cathepsin D, a lysosomal aspartic protease, is inhibited by SLC17A9 deficiency. Heterologous expression of Cathepsin D …
Expression of SLC17A9 in hepatocellular carcinoma and its clinical significance.
Wu J, Yang Y, Song J. Wu J, et al. Oncol Lett. 2020 Nov;20(5):182. doi: 10.3892/ol.2020.12043. Epub 2020 Aug 31. Oncol Lett. 2020. PMID: 32934749 Free PMC article.
The tumor-free survival (P=0.03) and overall survival (P=0.01) of SLC17A9-high expression patients were significantly lower than those in SLC17A9-low expression patients. ...In conclusion, SLC17A9 can be used as a new molecular marker to predict the poor prog …
The tumor-free survival (P=0.03) and overall survival (P=0.01) of SLC17A9-high expression patients were significantly lower than thos …
Comprehensive Analysis of SLC17A9 and Its Prognostic Value in Hepatocellular Carcinoma.
Kui XY, Gao Y, Liu XS, Zeng J, Yang JW, Zhou LM, Liu XY, Zhang Y, Zhang YH, Pei ZJ. Kui XY, et al. Front Oncol. 2022 Jul 25;12:809847. doi: 10.3389/fonc.2022.809847. eCollection 2022. Front Oncol. 2022. PMID: 35957868 Free PMC article.

RESULTS: SLC17A9 expression in LIHC tissues was higher than in normal liver tissues (p < 0.001), and SLC17A9 was related to sex, DSS (disease-specific survival), and PFI (progression-free interval) (p = 0.015, 0.006, and 0.023). ...GGI showed that SLC17A9

…

RESULTS: SLC17A9 expression in LIHC tissues was higher than in normal liver tissues (p < 0.001), and SLC17A9 was related to

…
VNUT/SLC17A9, a vesicular nucleotide transporter, regulates osteoblast differentiation.
Inoue A, Nakao-Kuroishi K, Kometani-Gunjigake K, Mizuhara M, Shirakawa T, Ito-Sago M, Yasuda K, Nakatomi M, Matsubara T, Tada-Shigeyama Y, Morikawa K, Kokabu S, Kawamoto T. Inoue A, et al. FEBS Open Bio. 2020 Aug;10(8):1612-1623. doi: 10.1002/2211-5463.12918. Epub 2020 Jul 12. FEBS Open Bio. 2020. PMID: 32592329 Free PMC article.
Recently, a vesicular nucleotide transporter [VNUT, solute carrier family 17 member 9 (SLC17A9)] that preserves ATP in vesicles has been identified. The purpose of this study was to elucidate the role of VNUT in osteoblast bone metabolism. mRNA and protein expression of VN …
Recently, a vesicular nucleotide transporter [VNUT, solute carrier family 17 member 9 (SLC17A9)] that preserves ATP in vesicles has b …
High expression of SLC17A9 correlates with poor prognosis in colorectal cancer.
Yang L, Chen Z, Xiong W, Ren H, Zhai E, Xu K, Yang H, Zhang Z, Ding L, He Y, Song X, Liu J. Yang L, et al. Hum Pathol. 2019 Feb;84:62-70. doi: 10.1016/j.humpath.2018.09.002. Epub 2018 Sep 18. Hum Pathol. 2019. PMID: 30236596
Solute carrier family 17 member 9 (SLC17A9) is a member of the family of transmembrane proteins that are involved in the transport of small molecules. The role of SLC17A9 in colorectal cancer (CRC) remains poorly understood. The present study aimed to demonstrate th …
Solute carrier family 17 member 9 (SLC17A9) is a member of the family of transmembrane proteins that are involved in the transport of …
SLC17A9 protein functions as a lysosomal ATP transporter and regulates cell viability.
Cao Q, Zhao K, Zhong XZ, Zou Y, Yu H, Huang P, Xu TL, Dong XP. Cao Q, et al. J Biol Chem. 2014 Aug 15;289(33):23189-23199. doi: 10.1074/jbc.M114.567107. Epub 2014 Jun 24. J Biol Chem. 2014. PMID: 24962569 Free PMC article.
Here, using mammalian cell lines, we report that SLC17A9 is highly enriched in lysosomes and functions as an ATP transporter in those organelles. SLC17A9 deficiency reduced lysosome ATP accumulation and compromised lysosome function, resulting in cell death. ...
Here, using mammalian cell lines, we report that SLC17A9 is highly enriched in lysosomes and functions as an ATP transporter in those …
99 results