Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35


O-GlcNAc modification of Sox2 regulates self-renewal in pancreatic cancer by promoting its stability.

Sharma NS, Gupta VK, Dauer P, Kesh K, Hadad R, Giri B, Chandra A, Dudeja V, Slawson C, Banerjee S, Vickers SM, Saluja A, Banerjee S.

Theranostics. 2019 May 24;9(12):3410-3424. doi: 10.7150/thno.32615. eCollection 2019.


Elevated O-GlcNAcylation enhances pro-inflammatory Th17 function by altering the intracellular lipid microenvironment.

Machacek M, Saunders H, Zhang Z, Tan EP, Li J, Li T, Villar MT, Artigues A, Lydic T, Cork G, Slawson C, Fields PE.

J Biol Chem. 2019 May 31;294(22):8973-8990. doi: 10.1074/jbc.RA119.008373. Epub 2019 Apr 22.


Disruption of O-GlcNAc homeostasis during mammalian oocyte meiotic maturation impacts fertilization.

Zhou LT, Romar R, Pavone ME, Soriano-Úbeda C, Zhang J, Slawson C, Duncan FE.

Mol Reprod Dev. 2019 May;86(5):543-557. doi: 10.1002/mrd.23131. Epub 2019 Feb 21.


O-GlcNAc homeostasis contributes to cell fate decisions during hematopoiesis.

Zhang Z, Parker MP, Graw S, Novikova LV, Fedosyuk H, Fontes JD, Koestler DC, Peterson KR, Slawson C.

J Biol Chem. 2019 Jan 25;294(4):1363-1379. doi: 10.1074/jbc.RA118.005993. Epub 2018 Dec 6.


Real Talk: The Inter-play Between the mTOR, AMPK, and Hexosamine Biosynthetic Pathways in Cell Signaling.

Cork GK, Thompson J, Slawson C.

Front Endocrinol (Lausanne). 2018 Sep 6;9:522. doi: 10.3389/fendo.2018.00522. eCollection 2018. Review.


New ways of thinking about old things: the role of O-GlcNAc in cellular metabolism.

Slawson C.

J Bioenerg Biomembr. 2018 Jun;50(3):153-154. doi: 10.1007/s10863-018-9762-z. Epub 2018 May 29. No abstract available.


O-GlcNAc: a novel regulator of immunometabolism.

Machacek M, Slawson C, Fields PE.

J Bioenerg Biomembr. 2018 Jun;50(3):223-229. doi: 10.1007/s10863-018-9744-1. Epub 2018 Feb 6. Review.


Modulation of O-GlcNAc Levels in the Liver Impacts Acetaminophen-Induced Liver Injury by Affecting Protein Adduct Formation and Glutathione Synthesis.

McGreal SR, Bhushan B, Walesky C, McGill MR, Lebofsky M, Kandel SE, Winefield RD, Jaeschke H, Zachara NE, Zhang Z, Tan EP, Slawson C, Apte U.

Toxicol Sci. 2018 Apr 1;162(2):599-610. doi: 10.1093/toxsci/kfy002.


O-GlcNAc-Dependent Regulation of Progesterone Receptor Function in Breast Cancer.

Trinca GM, Goodman ML, Papachristou EK, D'Santos CS, Chalise P, Madan R, Slawson C, Hagan CR.

Horm Cancer. 2018 Feb;9(1):12-21. doi: 10.1007/s12672-017-0310-9. Epub 2017 Sep 19.


Sustained O-GlcNAcylation reprograms mitochondrial function to regulate energy metabolism.

Tan EP, McGreal SR, Graw S, Tessman R, Koppel SJ, Dhakal P, Zhang Z, Machacek M, Zachara NE, Koestler DC, Peterson KR, Thyfault JP, Swerdlow RH, Krishnamurthy P, DiTacchio L, Apte U, Slawson C.

J Biol Chem. 2017 Sep 8;292(36):14940-14962. doi: 10.1074/jbc.M117.797944. Epub 2017 Jul 24.


A bioenergetics systems evaluation of ketogenic diet liver effects.

Hutfles LJ, Wilkins HM, Koppel SJ, Weidling IW, Selfridge JE, Tan E, Thyfault JP, Slawson C, Fenton AW, Zhu H, Swerdlow RH.

Appl Physiol Nutr Metab. 2017 Sep;42(9):955-962. doi: 10.1139/apnm-2017-0068. Epub 2017 May 17.


The sweet side of the cell cycle.

Tan EP, Duncan FE, Slawson C.

Biochem Soc Trans. 2017 Apr 15;45(2):313-322. doi: 10.1042/BST20160145. Review.


Changes in O-Linked N-Acetylglucosamine (O-GlcNAc) Homeostasis Activate the p53 Pathway in Ovarian Cancer Cells.

de Queiroz RM, Madan R, Chien J, Dias WB, Slawson C.

J Biol Chem. 2016 Sep 2;291(36):18897-914. doi: 10.1074/jbc.M116.734533. Epub 2016 Jul 11.


O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2β Protein at the Aγ-Globin Promoter.

Zhang Z, Costa FC, Tan EP, Bushue N, DiTacchio L, Costello CE, McComb ME, Whelan SA, Peterson KR, Slawson C.

J Biol Chem. 2016 Jul 22;291(30):15628-40. doi: 10.1074/jbc.M116.721928. Epub 2016 May 26.


Reduced O-GlcNAcase expression promotes mitotic errors and spindle defects.

Lanza C, Tan EP, Zhang Z, Machacek M, Brinker AE, Azuma M, Slawson C.

Cell Cycle. 2016 May 18;15(10):1363-75. doi: 10.1080/15384101.2016.1167297.


Sweet action: The dynamics of O-GlcNAcylation during meiosis in mouse oocytes.

Slawson C, Duncan FE.

Mol Reprod Dev. 2015 Dec;82(12):915. doi: 10.1002/mrd.22577. Review. No abstract available.


Removal of Abnormal Myofilament O-GlcNAcylation Restores Ca2+ Sensitivity in Diabetic Cardiac Muscle.

Ramirez-Correa GA, Ma J, Slawson C, Zeidan Q, Lugo-Fagundo NS, Xu M, Shen X, Gao WD, Caceres V, Chakir K, DeVine L, Cole RN, Marchionni L, Paolocci N, Hart GW, Murphy AM.

Diabetes. 2015 Oct;64(10):3573-87. doi: 10.2337/db14-1107. Epub 2015 Jun 24.


O-GlcNAcase Expression is Sensitive to Changes in O-GlcNAc Homeostasis.

Zhang Z, Tan EP, VandenHull NJ, Peterson KR, Slawson C.

Front Endocrinol (Lausanne). 2014 Dec 1;5:206. doi: 10.3389/fendo.2014.00206. eCollection 2014.


Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure.

Selfridge JE, Wilkins HM, E L, Carl SM, Koppel S, Funk E, Fields T, Lu J, Tang EP, Slawson C, Wang W, Zhu H, Swerdlow RH.

J Bioenerg Biomembr. 2015 Apr;47(1-2):1-11. doi: 10.1007/s10863-014-9570-z. Epub 2014 Aug 8.


Altering O-linked β-N-acetylglucosamine cycling disrupts mitochondrial function.

Tan EP, Villar MT, E L, Lu J, Selfridge JE, Artigues A, Swerdlow RH, Slawson C.

J Biol Chem. 2014 May 23;289(21):14719-30. doi: 10.1074/jbc.M113.525790. Epub 2014 Apr 8.


O-linked N-acetylglucosamine cycling regulates mitotic spindle organization.

Tan EP, Caro S, Potnis A, Lanza C, Slawson C.

J Biol Chem. 2013 Sep 20;288(38):27085-99. doi: 10.1074/jbc.M113.470187. Epub 2013 Aug 14.


NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-κB activation.

Gao X, Wang X, Pham TH, Feuerbacher LA, Lubos ML, Huang M, Olsen R, Mushegian A, Slawson C, Hardwidge PR.

Cell Host Microbe. 2013 Jan 16;13(1):87-99. doi: 10.1016/j.chom.2012.11.010. Epub 2013 Jan 16. Erratum in: Cell Host Microbe. 2013 Mar 13;13(3):371-2.


O-GlcNAc signalling: implications for cancer cell biology.

Slawson C, Hart GW.

Nat Rev Cancer. 2011 Aug 18;11(9):678-84. doi: 10.1038/nrc3114. Review.


Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease.

Hart GW, Slawson C, Ramirez-Correa G, Lagerlof O.

Annu Rev Biochem. 2011;80:825-58. doi: 10.1146/annurev-biochem-060608-102511. Review.


The E2F-1 associated retinoblastoma-susceptibility gene product is modified by O-GlcNAc.

Wells L, Slawson C, Hart GW.

Amino Acids. 2011 Mar;40(3):877-83. doi: 10.1007/s00726-010-0709-x. Epub 2010 Aug 1.


O-GlcNAc signaling: a metabolic link between diabetes and cancer?

Slawson C, Copeland RJ, Hart GW.

Trends Biochem Sci. 2010 Oct;35(10):547-55. doi: 10.1016/j.tibs.2010.04.005. Epub 2010 May 11. Review.


Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesis.

Wang Z, Udeshi ND, Slawson C, Compton PD, Sakabe K, Cheung WD, Shabanowitz J, Hunt DF, Hart GW.

Sci Signal. 2010 Jan 12;3(104):ra2. doi: 10.1126/scisignal.2000526.


O-linked N-acetylglucosamine modification on CCAAT enhancer-binding protein beta: role during adipocyte differentiation.

Li X, Molina H, Huang H, Zhang YY, Liu M, Qian SW, Slawson C, Dias WB, Pandey A, Hart GW, Lane MD, Tang QQ.

J Biol Chem. 2009 Jul 17;284(29):19248-54. doi: 10.1074/jbc.M109.005678. Epub 2009 May 28.


A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin.

Slawson C, Lakshmanan T, Knapp S, Hart GW.

Mol Biol Cell. 2008 Oct;19(10):4130-40. doi: 10.1091/mbc.E07-11-1146. Epub 2008 Jul 23.


Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins.

Hart GW, Housley MP, Slawson C.

Nature. 2007 Apr 26;446(7139):1017-22. Review.


O-GlcNAc cycling: how a single sugar post-translational modification is changing the way we think about signaling networks.

Slawson C, Housley MP, Hart GW.

J Cell Biochem. 2006 Jan 1;97(1):71-83. Review.


Perturbations in O-linked beta-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis.

Slawson C, Zachara NE, Vosseller K, Cheung WD, Lane MD, Hart GW.

J Biol Chem. 2005 Sep 23;280(38):32944-56. Epub 2005 Jul 18.


Dynamic interplay between O-GlcNAc and O-phosphate: the sweet side of protein regulation.

Slawson C, Hart GW.

Curr Opin Struct Biol. 2003 Oct;13(5):631-6. Review.


Characterization of the O-GlcNAc protein modification in Xenopus laevis oocyte during oogenesis and progesterone-stimulated maturation.

Slawson C, Shafii S, Amburgey J, Potter R.

Biochim Biophys Acta. 2002 Nov 14;1573(2):121-9.


Supplemental Content

Loading ...
Support Center