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Items: 1 to 50 of 53

1.

CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression.

Westrich JA, Vermeer DW, Silva A, Bonney S, Berger JN, Cicchini L, Greer RO, Song JI, Raben D, Slansky JE, Lee JH, Spanos WC, Pyeon D.

Oncogene. 2019 Aug 15. doi: 10.1038/s41388-019-0911-6. [Epub ahead of print]

PMID:
31417179
2.

IL12 Abrogates Calcineurin-Dependent Immune Evasion during Leukemia Progression.

Rabe JL, Gardner L, Hunter R, Fonseca JA, Dougan J, Gearheart CM, Leibowitz MS, Lee-Miller C, Baturin D, Fosmire SP, Zelasko SE, Jones CL, Slansky JE, Rupji M, Dwivedi B, Henry CJ, Porter CC.

Cancer Res. 2019 Jul 15;79(14):3702-3713. doi: 10.1158/0008-5472.CAN-18-3800. Epub 2019 May 29.

PMID:
31142509
3.

Alternative Splicing in Tumors - A Path to Immunogenicity?

Slansky JE, Spellman PT.

N Engl J Med. 2019 Feb 28;380(9):877-880. doi: 10.1056/NEJMcibr1814237. No abstract available.

PMID:
30811916
4.

Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts.

Capasso A, Lang J, Pitts TM, Jordan KR, Lieu CH, Davis SL, Diamond JR, Kopetz S, Barbee J, Peterson J, Freed BM, Yacob BW, Bagby SM, Messersmith WA, Slansky JE, Pelanda R, Eckhardt SG.

J Immunother Cancer. 2019 Feb 8;7(1):37. doi: 10.1186/s40425-019-0518-z.

5.

A Role for Tryptophan-2,3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma.

Greene LI, Bruno TC, Christenson JL, D'Alessandro A, Culp-Hill R, Torkko K, Borges VF, Slansky JE, Richer JK.

Mol Cancer Res. 2019 Jan;17(1):131-139. doi: 10.1158/1541-7786.MCR-18-0362. Epub 2018 Aug 24.

PMID:
30143553
6.

Eya3 promotes breast tumor-associated immune suppression via threonine phosphatase-mediated PD-L1 upregulation.

Vartuli RL, Zhou H, Zhang L, Powers RK, Klarquist J, Rudra P, Vincent MY, Ghosh D, Costello JC, Kedl RM, Slansky JE, Zhao R, Ford HL.

J Clin Invest. 2018 Jun 1;128(6):2535-2550. doi: 10.1172/JCI96784. Epub 2018 May 14.

7.

MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection.

Rozanov DV, Rozanov ND, Chiotti KE, Reddy A, Wilmarth PA, David LL, Cha SW, Woo S, Pevzner P, Bafna V, Burrows GG, Rantala JK, Levin T, Anur P, Johnson-Camacho K, Tabatabaei S, Munson DJ, Bruno TC, Slansky JE, Kappler JW, Hirano N, Boegel S, Fox BA, Egelston C, Simons DL, Jimenez G, Lee PP, Gray JW, Spellman PT.

J Proteomics. 2018 Mar 30;176:13-23. doi: 10.1016/j.jprot.2018.01.004. Epub 2018 Jan 10.

8.

Antigen-Presenting Intratumoral B Cells Affect CD4+ TIL Phenotypes in Non-Small Cell Lung Cancer Patients.

Bruno TC, Ebner PJ, Moore BL, Squalls OG, Waugh KA, Eruslanov EB, Singhal S, Mitchell JD, Franklin WA, Merrick DT, McCarter MD, Palmer BE, Kern JA, Slansky JE.

Cancer Immunol Res. 2017 Oct;5(10):898-907. doi: 10.1158/2326-6066.CIR-17-0075. Epub 2017 Aug 28.

9.

Shared αβ TCR Usage in Lungs of Sarcoidosis Patients with Löfgren's Syndrome.

Mitchell AM, Kaiser Y, Falta MT, Munson DJ, Landry LG, Eklund A, Nakayama M, Slansky JE, Grunewald J, Fontenot AP.

J Immunol. 2017 Oct 1;199(7):2279-2290. doi: 10.4049/jimmunol.1700570. Epub 2017 Aug 21.

10.

Molecular Profile of Tumor-Specific CD8+ T Cell Hypofunction in a Transplantable Murine Cancer Model.

Waugh KA, Leach SM, Moore BL, Bruno TC, Buhrman JD, Slansky JE.

J Immunol. 2016 Aug 15;197(4):1477-88. doi: 10.4049/jimmunol.1600589. Epub 2016 Jul 1.

11.

Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR.

Munson DJ, Egelston CA, Chiotti KE, Parra ZE, Bruno TC, Moore BL, Nakano TA, Simons DL, Jimenez G, Yim JH, Rozanov DV, Falta MT, Fontenot AP, Reynolds PR, Leach SM, Borges VF, Kappler JW, Spellman PT, Lee PP, Slansky JE.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8272-7. doi: 10.1073/pnas.1606994113. Epub 2016 Jun 15.

12.

Tolerance of Tumor-Specific T cells in Melanoma Metastases.

Waugh KA, Leach SM, Slansky JE.

J Clin Cell Immunol. 2016 Apr;7(2). pii: 409. Epub 2016 Apr 14. No abstract available.

13.

Flow Cytometric Analysis of Mononuclear Phagocytes in Nondiseased Human Lung and Lung-Draining Lymph Nodes.

Desch AN, Gibbings SL, Goyal R, Kolde R, Bednarek J, Bruno T, Slansky JE, Jacobelli J, Mason R, Ito Y, Messier E, Randolph GJ, Prabagar M, Atif SM, Segura E, Xavier RJ, Bratton DL, Janssen WJ, Henson PM, Jakubzick CV.

Am J Respir Crit Care Med. 2016 Mar 15;193(6):614-26. doi: 10.1164/rccm.201507-1376OC.

14.

Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor Immunity.

Waugh KA, Leach SM, Slansky JE.

Vaccines (Basel). 2015 Sep 17;3(3):771-802. doi: 10.3390/vaccines3030771. Review.

15.

Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction.

Desch AN, Gibbings SL, Clambey ET, Janssen WJ, Slansky JE, Kedl RM, Henson PM, Jakubzick C.

Nat Commun. 2014 Aug 19;5:4674. doi: 10.1038/ncomms5674.

16.

Improving antigenic peptide vaccines for cancer immunotherapy using a dominant tumor-specific T cell receptor.

Buhrman JD, Jordan KR, Munson DJ, Moore BL, Kappler JW, Slansky JE.

J Biol Chem. 2013 Nov 15;288(46):33213-25. doi: 10.1074/jbc.M113.509554. Epub 2013 Oct 8.

17.

Mimotope vaccine efficacy gets a "boost" from native tumor antigens.

Buhrman JD, Slansky JE.

Oncoimmunology. 2013 Apr 1;2(4):e23492.

18.

Augmenting antitumor T-cell responses to mimotope vaccination by boosting with native tumor antigens.

Buhrman JD, Jordan KR, U'ren L, Sprague J, Kemmler CB, Slansky JE.

Cancer Res. 2013 Jan 1;73(1):74-85. doi: 10.1158/0008-5472.CAN-12-1005. Epub 2012 Nov 16.

19.

Integrated immunology in Colorado.

Slansky JE, Cohen JJ, Cambier JC.

Immunol Res. 2013 Mar;55(1-3):1-2. doi: 10.1007/s12026-012-8376-5. No abstract available.

PMID:
22975788
20.

Influence of human immune cells on cancer: studies at the University of Colorado.

Bruno TC, French JD, Jordan KR, Ramirez O, Sippel TR, Borges VF, Haugen BR, McCarter MD, Waziri A, Slansky JE.

Immunol Res. 2013 Mar;55(1-3):22-33. doi: 10.1007/s12026-012-8346-y. Review.

21.

Improving T cell responses to modified peptides in tumor vaccines.

Buhrman JD, Slansky JE.

Immunol Res. 2013 Mar;55(1-3):34-47. doi: 10.1007/s12026-012-8348-9. Review.

22.
23.

TCR hypervariable regions expressed by T cells that respond to effective tumor vaccines.

Jordan KR, Buhrman JD, Sprague J, Moore BL, Gao D, Kappler JW, Slansky JE.

Cancer Immunol Immunother. 2012 Oct;61(10):1627-38. Epub 2012 Feb 21.

24.

Induction of remission results in spontaneous enhancement of anti-tumor cytotoxic T-lymphocyte activity in dogs with B cell lymphoma.

Mitchell L, Dow SW, Slansky JE, Biller BJ.

Vet Immunol Immunopathol. 2012 Feb 15;145(3-4):597-603. doi: 10.1016/j.vetimm.2012.01.006. Epub 2012 Jan 14.

PMID:
22293625
25.

Elevated tumor-associated antigen expression suppresses variant peptide vaccine responses.

Kemmler CB, Clambey ET, Kedl RM, Slansky JE.

J Immunol. 2011 Nov 1;187(9):4431-9. doi: 10.4049/jimmunol.1101555. Epub 2011 Sep 21.

26.

Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma.

Tamburini BA, Phang TL, Fosmire SP, Scott MC, Trapp SC, Duckett MM, Robinson SR, Slansky JE, Sharkey LC, Cutter GR, Wojcieszyn JW, Bellgrau D, Gemmill RM, Hunter LE, Modiano JF.

BMC Cancer. 2010 Nov 9;10:619. doi: 10.1186/1471-2407-10-619.

27.

The Goldilocks model for TCR-too much attraction might not be best for vaccine design.

Slansky JE, Jordan KR.

PLoS Biol. 2010 Sep 14;8(9). pii: e1000482. doi: 10.1371/journal.pbio.1000482. No abstract available.

28.

Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens.

Jordan KR, McMahan RH, Kemmler CB, Kappler JW, Slansky JE.

Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4652-7. doi: 10.1073/pnas.0914879107. Epub 2010 Jan 26. Erratum in: Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4788-9.

29.

Vaccination of mice with baculovirus-infected insect cells expressing antigenic proteins.

Jordan KR, Crawford F, Kappler JW, Slansky JE.

Curr Protoc Immunol. 2009 Apr;Chapter 2:Unit 2.15. doi: 10.1002/0471142735.im0215s85.

30.

Monitoring antigen-specific T cells using MHC-Ig dimers.

Schneck JP, Slansky JE, O'Herrin SM, Greten TF.

Curr Protoc Immunol. 2001 May;Chapter 17:Unit 17.2. doi: 10.1002/0471142735.im1702s35.

PMID:
18432743
31.

Age-dependent tolerance to an endogenous tumor-associated antigen.

McWilliams JA, Sullivan RT, Jordan KR, McMahan RH, Kemmler CB, McDuffie M, Slansky JE.

Vaccine. 2008 Mar 28;26(15):1863-1873. doi: 10.1016/j.vaccine.2008.01.052. Epub 2008 Feb 20.

32.

Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity.

Jordan KR, McMahan RH, Oh JZ, Pipeling MR, Pardoll DM, Kedl RM, Kappler JW, Slansky JE.

J Immunol. 2008 Jan 1;180(1):188-97.

33.

Live attenuated Listeria monocytogenes effectively treats hepatic colorectal cancer metastases and is strongly enhanced by depletion of regulatory T cells.

Yoshimura K, Laird LS, Chia CY, Meckel KF, Slansky JE, Thompson JM, Jain A, Pardoll DM, Schulick RD.

Cancer Res. 2007 Oct 15;67(20):10058-66.

34.

Mobilizing the low-avidity T cell repertoire to kill tumors.

McMahan RH, Slansky JE.

Semin Cancer Biol. 2007 Aug;17(4):317-29. Epub 2007 Jun 23. Review.

35.

Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines.

McMahan RH, McWilliams JA, Jordan KR, Dow SW, Wilson DB, Slansky JE.

J Clin Invest. 2006 Sep;116(9):2543-51. Epub 2006 Aug 24.

36.
37.

Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands.

Crawford F, Jordan KR, Stadinski B, Wang Y, Huseby E, Marrack P, Slansky JE, Kappler JW.

Immunol Rev. 2006 Apr;210:156-70. Review.

PMID:
16623770
38.

Selective targeting of antitumor immune responses with engineered live-attenuated Listeria monocytogenes.

Yoshimura K, Jain A, Allen HE, Laird LS, Chia CY, Ravi S, Brockstedt DG, Giedlin MA, Bahjat KS, Leong ML, Slansky JE, Cook DN, Dubensky TW, Pardoll DM, Schulick RD.

Cancer Res. 2006 Jan 15;66(2):1096-104.

39.

Antigen-specific T cells: analyses of the needles in the haystack.

Slansky JE.

PLoS Biol. 2003 Dec;1(3):E78. Epub 2003 Dec 22. Review. No abstract available.

40.
41.

Identification and characterization of the immunodominant rat HER-2/neu MHC class I epitope presented by spontaneous mammary tumors from HER-2/neu-transgenic mice.

Ercolini AM, Machiels JP, Chen YC, Slansky JE, Giedlen M, Reilly RT, Jaffee EM.

J Immunol. 2003 Apr 15;170(8):4273-80.

42.

Successful therapy of metastatic cancer using tumor vaccines in mixed allogeneic bone marrow chimeras.

Luznik L, Slansky JE, Jalla S, Borrello I, Levitsky HI, Pardoll DM, Fuchs EJ.

Blood. 2003 Feb 15;101(4):1645-52. Epub 2002 Oct 24.

PMID:
12406877
43.

Antigen-specific blockade of T cells in vivo using dimeric MHC peptide.

O'Herrin SM, Slansky JE, Tang Q, Markiewicz MA, Gajewski TF, Pardoll DM, Schneck JP, Bluestone JA.

J Immunol. 2001 Sep 1;167(5):2555-60.

44.

B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells.

Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, Shalabi A, Shin T, Pardoll DM, Tsuchiya H.

J Exp Med. 2001 Apr 2;193(7):839-46.

45.

Enhanced antigen-specific antitumor immunity with altered peptide ligands that stabilize the MHC-peptide-TCR complex.

Slansky JE, Rattis FM, Boyd LF, Fahmy T, Jaffee EM, Schneck JP, Margulies DH, Pardoll DM.

Immunity. 2000 Oct;13(4):529-38.

46.

Direct visualization of antigen-specific T cells: HTLV-1 Tax11-19- specific CD8(+) T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients.

Greten TF, Slansky JE, Kubota R, Soldan SS, Jaffee EM, Leist TP, Pardoll DM, Jacobson S, Schneck JP.

Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7568-73.

47.
48.

Transcriptional regulation of the dihydrofolate reductase gene.

Slansky JE, Farnham PJ.

Bioessays. 1996 Jan;18(1):55-62. Review.

PMID:
8593164
49.

Introduction to the E2F family: protein structure and gene regulation.

Slansky JE, Farnham PJ.

Curr Top Microbiol Immunol. 1996;208:1-30. Review.

PMID:
8575210
50.

Cloning, chromosomal location, and characterization of mouse E2F1.

Li Y, Slansky JE, Myers DJ, Drinkwater NR, Kaelin WG, Farnham PJ.

Mol Cell Biol. 1994 Mar;14(3):1861-9.

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