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Items: 50

1.

Relative Abundance of Integrant-Derived Viral RNAs in Infected Tissues Harvested from Chronic Hepatitis B Virus Carriers.

Freitas N, Lukash T, Gunewardena S, Chappell B, Slagle BL, Gudima SO.

J Virol. 2018 Apr 27;92(10). pii: e02221-17. doi: 10.1128/JVI.02221-17. Print 2018 May 15.

2.

Role of HBx in hepatitis B virus persistence and its therapeutic implications.

Slagle BL, Bouchard MJ.

Curr Opin Virol. 2018 Jun;30:32-38. doi: 10.1016/j.coviro.2018.01.007. Epub 2018 Feb 20. Review.

3.

Farnesoid X receptor ablation sensitizes mice to hepatitis b virus X protein-induced hepatocarcinogenesis.

Niu Y, Xu M, Slagle BL, Huang H, Li S, Guo GL, Shi G, Qin W, Xie W.

Hepatology. 2017 Mar;65(3):893-906. doi: 10.1002/hep.28924. Epub 2017 Jan 19.

4.

Hepatitis B Virus X and Regulation of Viral Gene Expression.

Slagle BL, Bouchard MJ.

Cold Spring Harb Perspect Med. 2016 Jan 8;6(3):a021402. doi: 10.1101/cshperspect.a021402. Review.

5.

Activation of signal transduction pathways during hepatic oncogenesis.

Chung W, Kim M, de la Monte S, Longato L, Carlson R, Slagle BL, Dong X, Wands JR.

Cancer Lett. 2016 Jan 1;370(1):1-9. doi: 10.1016/j.canlet.2015.09.016. Epub 2015 Oct 1.

6.

Hepatitis B virus HBx protein interactions with the ubiquitin proteasome system.

Minor MM, Slagle BL.

Viruses. 2014 Nov 24;6(11):4683-702. doi: 10.3390/v6114683. Review.

7.

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes.

Totoki Y, Tatsuno K, Covington KR, Ueda H, Creighton CJ, Kato M, Tsuji S, Donehower LA, Slagle BL, Nakamura H, Yamamoto S, Shinbrot E, Hama N, Lehmkuhl M, Hosoda F, Arai Y, Walker K, Dahdouli M, Gotoh K, Nagae G, Gingras MC, Muzny DM, Ojima H, Shimada K, Midorikawa Y, Goss JA, Cotton R, Hayashi A, Shibahara J, Ishikawa S, Guiteau J, Tanaka M, Urushidate T, Ohashi S, Okada N, Doddapaneni H, Wang M, Zhu Y, Dinh H, Okusaka T, Kokudo N, Kosuge T, Takayama T, Fukayama M, Gibbs RA, Wheeler DA, Aburatani H, Shibata T.

Nat Genet. 2014 Dec;46(12):1267-73. doi: 10.1038/ng.3126. Epub 2014 Nov 2.

PMID:
25362482
8.

Technical standards for hepatitis B virus X protein (HBx) research.

Slagle BL, Andrisani OM, Bouchard MJ, Lee CG, Ou JH, Siddiqui A.

Hepatology. 2015 Apr;61(4):1416-24. doi: 10.1002/hep.27360. Epub 2015 Mar 9. Review.

9.

The C-terminal region of the hepatitis B virus X protein is required for its stimulation of HBV replication in primary mouse hepatocytes.

Luo N, Cai Y, Zhang J, Tang W, Slagle BL, Wu X, He S.

Virus Res. 2012 May;165(2):170-8. doi: 10.1016/j.virusres.2012.02.013. Epub 2012 Feb 23.

PMID:
22387566
10.

Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication.

Hodgson AJ, Hyser JM, Keasler VV, Cang Y, Slagle BL.

Virology. 2012 Apr 25;426(1):73-82. doi: 10.1016/j.virol.2012.01.021. Epub 2012 Feb 17.

11.

Hepatitis B virus regulatory HBx protein binds to adaptor protein IPS-1 and inhibits the activation of beta interferon.

Kumar M, Jung SY, Hodgson AJ, Madden CR, Qin J, Slagle BL.

J Virol. 2011 Jan;85(2):987-95. doi: 10.1128/JVI.01825-10. Epub 2010 Nov 10.

12.

NF-kappaB signaling mediates the induction of MTA1 by hepatitis B virus transactivator protein HBx.

Bui-Nguyen TM, Pakala SB, Sirigiri RD, Xia W, Hung MC, Sarin SK, Kumar V, Slagle BL, Kumar R.

Oncogene. 2010 Feb 25;29(8):1179-89. doi: 10.1038/onc.2009.404. Epub 2009 Dec 14.

13.

Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liver.

Longato L, de la Monte S, Kuzushita N, Horimoto M, Rogers AB, Slagle BL, Wands JR.

Hepatology. 2009 Jun;49(6):1935-43. doi: 10.1002/hep.22856.

14.

Hepatitis B virus HBx protein localized to the nucleus restores HBx-deficient virus replication in HepG2 cells and in vivo in hydrodynamically-injected mice.

Keasler VV, Hodgson AJ, Madden CR, Slagle BL.

Virology. 2009 Jul 20;390(1):122-9. doi: 10.1016/j.virol.2009.05.001. Epub 2009 May 23.

15.

Premature cell cycle entry induced by hepatitis B virus regulatory HBx protein during compensatory liver regeneration.

Hodgson AJ, Keasler VV, Slagle BL.

Cancer Res. 2008 Dec 15;68(24):10341-8. doi: 10.1158/0008-5472.CAN-08-2695.

16.

Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype.

Connolly E, Melegari M, Landgraf P, Tchaikovskaya T, Tennant BC, Slagle BL, Rogler LE, Zavolan M, Tuschl T, Rogler CE.

Am J Pathol. 2008 Sep;173(3):856-64. doi: 10.2353/ajpath.2008.080096. Epub 2008 Aug 7.

17.

Enhancement of hepatitis B virus replication by the regulatory X protein in vitro and in vivo.

Keasler VV, Hodgson AJ, Madden CR, Slagle BL.

J Virol. 2007 Mar;81(6):2656-62. Epub 2006 Dec 20.

18.

Increased liver pathology in hepatitis C virus transgenic mice expressing the hepatitis B virus X protein.

Keasler VV, Lerat H, Madden CR, Finegold MJ, McGarvey MJ, Mohammed EM, Forbes SJ, Lemon SM, Hadsell DL, Grona SJ, Hollinger FB, Slagle BL.

Virology. 2006 Apr 10;347(2):466-75. Epub 2006 Jan 20.

19.
20.

Enhancement of hepatitis B virus replication by its X protein in transgenic mice.

Xu Z, Yen TS, Wu L, Madden CR, Tan W, Slagle BL, Ou JH.

J Virol. 2002 Mar;76(5):2579-84.

21.

Stimulation of cellular proliferation by hepatitis B virus X protein.

Madden CR, Slagle BL.

Dis Markers. 2001;17(3):153-7. Review.

22.

DDB2 induces nuclear accumulation of the hepatitis B virus X protein independently of binding to DDB1.

Nag A, Datta A, Yoo K, Bhattacharyya D, Chakrabortty A, Wang X, Slagle BL, Costa RH, Raychaudhuri P.

J Virol. 2001 Nov;75(21):10383-92.

23.

Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue.

Jaitovich-Groisman I, Benlimame N, Slagle BL, Perez MH, Alpert L, Song DJ, Fotouhi-Ardakani N, Galipeau J, Alaoui-Jamali MA.

J Biol Chem. 2001 Apr 27;276(17):14124-32. Epub 2001 Jan 25.

24.
25.

Dissociation of DDB1-binding and transactivation properties of the hepatitis B virus X protein.

Wentz MJ, Becker SA, Slagle BL.

Virus Res. 2000 Jun;68(1):87-92.

PMID:
10930665
26.
27.

The naturally occurring mutants of DDB are impaired in stimulating nuclear import of the p125 subunit and E2F1-activated transcription.

Shiyanov P, Hayes SA, Donepudi M, Nichols AF, Linn S, Slagle BL, Raychaudhuri P.

Mol Cell Biol. 1999 Jul;19(7):4935-43.

28.

Hepatitis B virus-induced liver injury and altered expression of carcinogen metabolising enzymes: the role of the HBx protein.

Chomarat P, Rice JM, Slagle BL, Wild CP.

Toxicol Lett. 1998 Dec 28;102-103:595-601.

PMID:
10022319
29.

Expression of ras, c-myc, and p53 proteins in cervical intraepithelial neoplasia.

Slagle BL, Kaufman RH, Reeves WC, Icenogle JP.

Cancer. 1998 Oct 1;83(7):1401-8.

PMID:
9762942
30.

Hepatitis B virus X protein interferes with cellular DNA repair.

Becker SA, Lee TH, Butel JS, Slagle BL.

J Virol. 1998 Jan;72(1):266-72.

31.
32.

Activation of the HTLV-I long terminal repeat by the hepatitis B virus X protein.

Marriott SJ, Lee TH, Slagle BL, Butel JS.

Virology. 1996 Oct 1;224(1):206-13.

33.

Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene.

Slagle BL, Lee TH, Medina D, Finegold MJ, Butel JS.

Mol Carcinog. 1996 Apr;15(4):261-9.

PMID:
8634084
34.

Is the DNA repair system involved in hepatitis-B-virus-mediated hepatocellular carcinogenesis?

Butel JS, Lee TH, Slagle BL.

Trends Microbiol. 1996 Mar;4(3):119-24. Review. No abstract available.

PMID:
8868091
35.

Induction of senescent cell-derived inhibitor of DNA synthesis gene, SDI1, in hepatoblastoma (HepG2) cells arrested in the G2-phase of the cell cycle by 9-nitrocamptothecin.

Khaoustov VI, Ozer A, Smith JR, Noda A, Mearns M, Krishnan B, Slagle BL, Yoffe B.

Lab Invest. 1995 Jul;73(1):118-27.

PMID:
7603034
36.

p53 mutations and hepatitis B virus: cofactors in hepatocellular carcinoma.

Slagle BL.

Hepatology. 1995 Feb;21(2):597-9. No abstract available.

PMID:
7843736
37.

Viral co-factors in liver cancer: lessons from hepatitis B virus.

Butel JS, Lee TH, Slagle BL.

Princess Takamatsu Symp. 1995;25:185-98. Review.

PMID:
8875624
38.

Allelotype and loss of heterozygosity of p53 in primary and recurrent hepatocellular carcinomas. A study of 150 patients.

Hsu HC, Peng SY, Lai PL, Sheu JC, Chen DS, Lin LI, Slagle BL, Butel JS.

Cancer. 1994 Jan 1;73(1):42-7.

PMID:
7506118
39.

Deletion of the E-cadherin gene in hepatitis B virus-positive Chinese hepatocellular carcinomas.

Slagle BL, Zhou YZ, Birchmeier W, Scorsone KA.

Hepatology. 1993 Oct;18(4):757-62.

PMID:
8104855
40.

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours.

Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA Jr, Butel JS, Bradley A.

Nature. 1992 Mar 19;356(6366):215-21.

PMID:
1552940
41.

p53 mutations cluster at codon 249 in hepatitis B virus-positive hepatocellular carcinomas from China.

Scorsone KA, Zhou YZ, Butel JS, Slagle BL.

Cancer Res. 1992 Mar 15;52(6):1635-8.

42.

Hepatitis B virus and hepatocellular carcinoma.

Slagle BL, Lee TH, Butel JS.

Prog Med Virol. 1992;39:167-203. Review. No abstract available.

PMID:
1317597
45.

Identification of a conserved sequence in the non-coding regions of many human genes.

Donehower LA, Slagle BL, Wilde M, Darlington G, Butel JS.

Nucleic Acids Res. 1989 Jan 25;17(2):699-710.

46.

Structural analysis of a hepatitis B virus genome integrated into chromosome 17p of a human hepatocellular carcinoma.

Zhou YZ, Slagle BL, Donehower LA, vanTuinen P, Ledbetter DH, Butel JS.

J Virol. 1988 Nov;62(11):4224-31.

47.

Mammary cancer stages in BALB/cV mice: mouse mammary tumor virus expression and virus-host interactions.

Slagle BL, Medina D, Butel JS.

J Natl Cancer Inst. 1987 Aug;79(2):323-35.

PMID:
3037152
49.

Molecular basis of altered mouse mammary tumor virus expression in the D-2 hyperplastic alveolar nodule line of BALB/c mice.

Slagle BL, Wheeler DA, Hager GL, Medina D, Butel JS.

Virology. 1985 May;143(1):1-15.

PMID:
2414907
50.

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