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Items: 32

1.

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals.

Mandaviya PR, Joehanes R, Brody J, Castillo-Fernandez JE, Dekkers KF, Do AN, Graff M, Hänninen IK, Tanaka T, de Jonge EAL, Kiefte-de Jong JC, Absher DM, Aslibekyan S, de Rijke YB, Fornage M, Hernandez DG, Hurme MA, Ikram MA, Jacques PF, Justice AE, Kiel DP, Lemaitre RN, Mendelson MM, Mikkilä V, Moore AZ, Pallister T, Raitakari OT, Schalkwijk CG, Sha J, Slagboom EPE, Smith CE, Stehouwer CDA, Tsai PC, Uitterlinden AG, van der Kallen CJH, van Heemst D, Arnett DK, Bandinelli S, Bell JT, Heijmans BT, Lehtimäki T, Levy D, North KE, Sotoodehnia N, van Greevenbroek MMJ, van Meurs JBJ, Heil SG.

Am J Clin Nutr. 2019 Aug 1;110(2):437-450. doi: 10.1093/ajcn/nqz031.

PMID:
31165884
2.

Annotating Transcriptional Effects of Genetic Variants in Disease-Relevant Tissue: Transcriptome-Wide Allelic Imbalance in Osteoarthritic Cartilage.

den Hollander W, Pulyakhina I, Boer C, Bomer N, van der Breggen R, Arindrarto W, Couthino de Almeida R, Lakenberg N, Sentner T, Laros JFJ, 't Hoen PAC, Slagboom EPE, Nelissen RGHH, van Meurs J, Ramos YFM, Meulenbelt I.

Arthritis Rheumatol. 2019 Apr;71(4):561-570. doi: 10.1002/art.40748. Epub 2019 Feb 23.

3.

Correction: The complex genetics of gait speed: genome-wide meta-analysis approach.

Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SLR, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G.

Aging (Albany NY). 2017 Jul;9(7):1844-1846. doi: 10.18632/aging.101260. Epub 2017 Jul 7. No abstract available.

4.

The complex genetics of gait speed: genome-wide meta-analysis approach.

Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SL, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G.

Aging (Albany NY). 2017 Jan 10;9(1):209-246. doi: 10.18632/aging.101151. Erratum in: Aging (Albany NY). 2017 Jul 7;9(7):1844-1846.

5.

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.

Castaño-Betancourt MC, Evans DS, Ramos YF, Boer CG, Metrustry S, Liu Y, den Hollander W, van Rooij J, Kraus VB, Yau MS, Mitchell BD, Muir K, Hofman A, Doherty M, Doherty S, Zhang W, Kraaij R, Rivadeneira F, Barrett-Connor E, Maciewicz RA, Arden N, Nelissen RG, Kloppenburg M, Jordan JM, Nevitt MC, Slagboom EP, Hart DJ, Lafeber F, Styrkarsdottir U, Zeggini E, Evangelou E, Spector TD, Uitterlinden AG, Lane NE, Meulenbelt I, Valdes AM, van Meurs JB.

PLoS Genet. 2016 Oct 4;12(10):e1006260. doi: 10.1371/journal.pgen.1006260. eCollection 2016 Oct.

6.

Maternal and child cytokine relationship in early life is not altered by cytokine gene polymorphisms.

Djuardi Y, Supali T, Wibowo H, Heijmans BT, Deelen J, Slagboom EP, Houwing-Duistermaat JJ, Sartono E, Yazdanbakhsh M.

Genes Immun. 2016 Dec;17(7):380-385. doi: 10.1038/gene.2016.35. Epub 2016 Sep 1.

7.

Survival analysis with delayed entry in selected families with application to human longevity.

Rodríguez-Girondo M, Deelen J, Slagboom EP, Houwing-Duistermaat JJ.

Stat Methods Med Res. 2018 Mar;27(3):933-954. doi: 10.1177/0962280216648356. Epub 2016 May 13.

8.

Associations between insulin action and integrity of brain microstructure differ with familial longevity and with age.

Akintola AA, van den Berg A, van Buchem MA, Jansen SW, Slagboom EP, Westendorp RG, van der Grond J, van Heemst D.

Front Aging Neurosci. 2015 May 28;7:92. doi: 10.3389/fnagi.2015.00092. eCollection 2015.

9.

Genetically determined prospect to become long-lived is associated with less abdominal fat and in particular less abdominal visceral fat in men.

Sala ML, Röell B, van der Bijl N, van der Grond J, de Craen AJ, Slagboom EP, van der Geest R, de Roos A, Kroft LJ.

Age Ageing. 2015 Jul;44(4):713-7. doi: 10.1093/ageing/afv063. Epub 2015 May 16.

PMID:
25983277
10.

Mobster: accurate detection of mobile element insertions in next generation sequencing data.

Thung DT, de Ligt J, Vissers LE, Steehouwer M, Kroon M, de Vries P, Slagboom EP, Ye K, Veltman JA, Hehir-Kwa JY.

Genome Biol. 2014;15(10):488.

11.

An alternative approach to multiple testing for methylation QTL mapping reduces the proportion of falsely identified CpGs.

Luijk R, Goeman JJ, Slagboom EP, Heijmans BT, van Zwet EW.

Bioinformatics. 2015 Feb 1;31(3):340-5. doi: 10.1093/bioinformatics/btu654. Epub 2014 Oct 4.

PMID:
25282645
12.

Latent infection with cytomegalovirus is associated with poor memory CD4 responses to influenza A core proteins in the elderly.

Derhovanessian E, Maier AB, Hähnel K, McElhaney JE, Slagboom EP, Pawelec G.

J Immunol. 2014 Oct 1;193(7):3624-31. doi: 10.4049/jimmunol.1303361. Epub 2014 Sep 3.

13.

Integrating metabolomics profiling measurements across multiple biobanks.

Dane AD, Hendriks MM, Reijmers TH, Harms AC, Troost J, Vreeken RJ, Boomsma DI, van Duijn CM, Slagboom EP, Hankemeier T.

Anal Chem. 2014 May 6;86(9):4110-4. doi: 10.1021/ac404191a. Epub 2014 Apr 16.

PMID:
24650176
14.

Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis.

Valdes AM, Meulenbelt I, Chassaing E, Arden NK, Bierma-Zeinstra S, Hart D, Hofman A, Karsdal M, Kloppenburg M, Kroon HM, Slagboom EP, Spector TD, Uitterlinden AG, van Meurs JB, Bay-Jensen AC.

Osteoarthritis Cartilage. 2014 May;22(5):683-9. doi: 10.1016/j.joca.2014.02.007. Epub 2014 Feb 25.

15.

The Genome of the Netherlands: design, and project goals.

Boomsma DI, Wijmenga C, Slagboom EP, Swertz MA, Karssen LC, Abdellaoui A, Ye K, Guryev V, Vermaat M, van Dijk F, Francioli LC, Hottenga JJ, Laros JF, Li Q, Li Y, Cao H, Chen R, Du Y, Li N, Cao S, van Setten J, Menelaou A, Pulit SL, Hehir-Kwa JY, Beekman M, Elbers CC, Byelas H, de Craen AJ, Deelen P, Dijkstra M, den Dunnen JT, de Knijff P, Houwing-Duistermaat J, Koval V, Estrada K, Hofman A, Kanterakis A, Enckevort Dv, Mai H, Kattenberg M, van Leeuwen EM, Neerincx PB, Oostra B, Rivadeneira F, Suchiman EH, Uitterlinden AG, Willemsen G, Wolffenbuttel BH, Wang J, de Bakker PI, van Ommen GJ, van Duijn CM.

Eur J Hum Genet. 2014 Feb;22(2):221-7. doi: 10.1038/ejhg.2013.118. Epub 2013 May 29.

16.

Lipidomics of familial longevity.

Gonzalez-Covarrubias V, Beekman M, Uh HW, Dane A, Troost J, Paliukhovich I, van der Kloet FM, Houwing-Duistermaat J, Vreeken RJ, Hankemeier T, Slagboom EP.

Aging Cell. 2013 Jun;12(3):426-34. doi: 10.1111/acel.12064. Epub 2013 Apr 2.

17.

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.

Porcu E, Medici M, Pistis G, Volpato CB, Wilson SG, Cappola AR, Bos SD, Deelen J, den Heijer M, Freathy RM, Lahti J, Liu C, Lopez LM, Nolte IM, O'Connell JR, Tanaka T, Trompet S, Arnold A, Bandinelli S, Beekman M, Böhringer S, Brown SJ, Buckley BM, Camaschella C, de Craen AJ, Davies G, de Visser MC, Ford I, Forsen T, Frayling TM, Fugazzola L, Gögele M, Hattersley AT, Hermus AR, Hofman A, Houwing-Duistermaat JJ, Jensen RA, Kajantie E, Kloppenburg M, Lim EM, Masciullo C, Mariotti S, Minelli C, Mitchell BD, Nagaraja R, Netea-Maier RT, Palotie A, Persani L, Piras MG, Psaty BM, Räikkönen K, Richards JB, Rivadeneira F, Sala C, Sabra MM, Sattar N, Shields BM, Soranzo N, Starr JM, Stott DJ, Sweep FC, Usala G, van der Klauw MM, van Heemst D, van Mullem A, Vermeulen SH, Visser WE, Walsh JP, Westendorp RG, Widen E, Zhai G, Cucca F, Deary IJ, Eriksson JG, Ferrucci L, Fox CS, Jukema JW, Kiemeney LA, Pramstaller PP, Schlessinger D, Shuldiner AR, Slagboom EP, Uitterlinden AG, Vaidya B, Visser TJ, Wolffenbuttel BH, Meulenbelt I, Rotter JI, Spector TD, Hicks AA, Toniolo D, Sanna S, Peeters RP, Naitza S.

PLoS Genet. 2013;9(2):e1003266. doi: 10.1371/journal.pgen.1003266. Epub 2013 Feb 7.

18.

Lower proportion of naïve peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people.

Derhovanessian E, Maier AB, Hähnel K, Zelba H, de Craen AJ, Roelofs H, Slagboom EP, Westendorp RG, Pawelec G.

Age (Dordr). 2013 Aug;35(4):1387-99. doi: 10.1007/s11357-012-9425-7. Epub 2012 Jun 4.

19.

Distinguishing between longevity and buffered-deleterious genotypes for exceptional human longevity: the case of the MTP gene.

Huffman DM, Deelen J, Ye K, Bergman A, Slagboom EP, Barzilai N, Atzmon G.

J Gerontol A Biol Sci Med Sci. 2012 Nov;67(11):1153-60. doi: 10.1093/gerona/gls103. Epub 2012 Apr 10.

20.

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes.

Webb BT, Guo AY, Maher BS, Zhao Z, van den Oord EJ, Kendler KS, Riley BP, Gillespie NA, Prescott CA, Middeldorp CM, Willemsen G, de Geus EJ, Hottenga JJ, Boomsma DI, Slagboom EP, Wray NR, Montgomery GW, Martin NG, Wright MJ, Heath AC, Madden PA, Gelernter J, Knowles JA, Hamilton SP, Weissman MM, Fyer AJ, Huezo-Diaz P, McGuffin P, Farmer A, Craig IW, Lewis C, Sham P, Crowe RR, Flint J, Hettema JM.

Eur J Hum Genet. 2012 Oct;20(10):1078-84. doi: 10.1038/ejhg.2012.47. Epub 2012 Apr 4.

21.

Infection with cytomegalovirus but not herpes simplex virus induces the accumulation of late-differentiated CD4+ and CD8+ T-cells in humans.

Derhovanessian E, Maier AB, Hähnel K, Beck R, de Craen AJ, Slagboom EP, Westendorp RG, Pawelec G.

J Gen Virol. 2011 Dec;92(Pt 12):2746-56. doi: 10.1099/vir.0.036004-0. Epub 2011 Aug 3.

PMID:
21813708
22.

ADHD in Dutch adults: heritability and linkage study.

Saviouk V, Hottenga JJ, Slagboom EP, Distel MA, de Geus EJ, Willemsen G, Boomsma DI.

Am J Med Genet B Neuropsychiatr Genet. 2011 Apr;156B(3):352-62. doi: 10.1002/ajmg.b.31170. Epub 2011 Feb 3.

PMID:
21294247
23.

C-reactive protein and glucose regulation in familial longevity.

Rozing MP, Mooijaart SP, Beekman M, Wijsman CA, Maier AB, Bartke A, Westendorp RG, Slagboom EP, van Heemst D.

Age (Dordr). 2011 Dec;33(4):623-30. doi: 10.1007/s11357-011-9206-8. Epub 2011 Jan 19.

24.

Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis.

Kerkhof HJ, Meulenbelt I, Carr A, Gonzalez A, Hart D, Hofman A, Kloppenburg M, Lane NE, Loughlin J, Nevitt MC, Pols HA, Rivadeneira F, Slagboom EP, Spector TD, Stolk L, Tsezou A, Uitterlinden AG, Valdes AM, van Meurs JB.

BMC Med Genet. 2010 Nov 16;11:164. doi: 10.1186/1471-2350-11-164.

25.

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.

Kerkhof HJ, Lories RJ, Meulenbelt I, Jonsdottir I, Valdes AM, Arp P, Ingvarsson T, Jhamai M, Jonsson H, Stolk L, Thorleifsson G, Zhai G, Zhang F, Zhu Y, van der Breggen R, Carr A, Doherty M, Doherty S, Felson DT, Gonzalez A, Halldorsson BV, Hart DJ, Hauksson VB, Hofman A, Ioannidis JP, Kloppenburg M, Lane NE, Loughlin J, Luyten FP, Nevitt MC, Parimi N, Pols HA, Rivadeneira F, Slagboom EP, Styrkársdóttir U, Tsezou A, van de Putte T, Zmuda J, Spector TD, Stefansson K, Uitterlinden AG, van Meurs JB.

Arthritis Rheum. 2010 Feb;62(2):499-510. doi: 10.1002/art.27184.

26.

Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations.

Meulenbelt I, Chapman K, Dieguez-Gonzalez R, Shi D, Tsezou A, Dai J, Malizos KN, Kloppenburg M, Carr A, Nakajima M, van der Breggen R, Lakenberg N, Gomez-Reino JJ, Jiang Q, Ikegawa S, Gonzalez A, Loughlin J, Slagboom EP.

Hum Mol Genet. 2009 Apr 15;18(8):1518-23. doi: 10.1093/hmg/ddp053. Epub 2009 Jan 30.

PMID:
19181678
27.

Genome-wide association scan for five major dimensions of personality.

Terracciano A, Sanna S, Uda M, Deiana B, Usala G, Busonero F, Maschio A, Scally M, Patriciu N, Chen WM, Distel MA, Slagboom EP, Boomsma DI, Villafuerte S, Sliwerska E, Burmeister M, Amin N, Janssens AC, van Duijn CM, Schlessinger D, Abecasis GR, Costa PT Jr.

Mol Psychiatry. 2010 Jun;15(6):647-56. doi: 10.1038/mp.2008.113. Epub 2008 Oct 28.

28.

Testing the druggable endothelial differentiation gene 2 knee osteoarthritis genetic factor for replication in a wide range of sample collections.

Dieguez-Gonzalez R, Calaza M, Shi D, Meulenbelt I, Loughlin J, Tsezou A, Dai J, Malizos KN, Slagboom EP, Kloppenburg M, Chapman K, Jiang Q, Kremer D, Gomez-Reino JJ, Nakajima N, Ikegawa S, Gonzalez A.

Ann Rheum Dis. 2009 Jun;68(6):1017-21. doi: 10.1136/ard.2008.093641. Epub 2008 Jul 14.

PMID:
18625619
29.

Amino acid profiling in urine by capillary zone electrophoresis - mass spectrometry.

Mayboroda OA, Neusüss C, Pelzing M, Zurek G, Derks R, Meulenbelt I, Kloppenburg M, Slagboom EP, Deelder AM.

J Chromatogr A. 2007 Aug 3;1159(1-2):149-53. Epub 2007 Apr 29.

PMID:
17540385
30.

A unified approach to modelling linkage to quantitative and qualitative traits.

Houwing-Duistermaat JJ, Bijkerk C, Hsu L, Stijnen T, Slagboom EP, van Duijn CM.

Ann Hum Genet. 2003 Sep;67(Pt 5):457-63.

PMID:
12940918
31.

Mortality risk in men is associated with a common mutation in the methylene-tetrahydrofolate reductase gene (MTHFR).

Heijmans BT, Gussekloo J, Kluft C, Droog S, Lagaay AM, Knook DL, Westendorp RG, Slagboom EP.

Eur J Hum Genet. 1999 Feb-Mar;7(2):197-204.

32.

Genome scanning by two-dimensional DNA typing: the use of repetitive DNA sequences for rapid mapping of genetic traits.

Uitterlinden AG, Slagboom EP, Mullaart E, Meulenbelt I, Vijg J.

Electrophoresis. 1991 Feb-Mar;12(2-3):119-34.

PMID:
1674908

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