Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 69

1.

HNF4α-deficient Fatty Liver Provides a Permissive Environment for Sex-independent Hepatocellular Carcinoma.

Fekry B, Ribas Latre A, Baumgartner C, Mohamed AMT, Kolonin MG, Sladek FM, Younes M, Eckel-Mahan KL.

Cancer Res. 2019 Oct 1. pii: canres.1277.2019. doi: 10.1158/0008-5472.CAN-19-1277. [Epub ahead of print]

PMID:
31575546
2.

Fourniers gangrene as Amyands hernia complication.

Sládek F, Krass V, Salaš O, Sutorý M, Paša L.

Rozhl Chir. 2019 Summer;98(7):291-296.

PMID:
31398990
3.

Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver.

Deol P, Yang J, Morisseau C, Hammock BD, Sladek FM.

Front Pharmacol. 2019 May 29;10:580. doi: 10.3389/fphar.2019.00580. eCollection 2019.

4.

Incompatibility of the circadian protein BMAL1 and HNF4α in hepatocellular carcinoma.

Fekry B, Ribas-Latre A, Baumgartner C, Deans JR, Kwok C, Patel P, Fu L, Berdeaux R, Sun K, Kolonin MG, Wang SH, Yoo SH, Sladek FM, Eckel-Mahan K.

Nat Commun. 2018 Oct 19;9(1):4349. doi: 10.1038/s41467-018-06648-6.

5.

Conservation of DNA and ligand binding properties of retinoid X receptor from the placozoan Trichoplax adhaerens to human.

Reitzel AM, Macrander J, Mane-Padros D, Fang B, Sladek FM, Tarrant AM.

J Steroid Biochem Mol Biol. 2018 Nov;184:3-10. doi: 10.1016/j.jsbmb.2018.02.010. Epub 2018 Mar 3. Review.

PMID:
29510228
6.

Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice.

Deol P, Fahrmann J, Yang J, Evans JR, Rizo A, Grapov D, Salemi M, Wanichthanarak K, Fiehn O, Phinney B, Hammock BD, Sladek FM.

Sci Rep. 2017 Oct 2;7(1):12488. doi: 10.1038/s41598-017-12624-9.

7.

Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs.

Allevato M, Bolotin E, Grossman M, Mane-Padros D, Sladek FM, Martinez E.

PLoS One. 2017 Jul 18;12(7):e0180147. doi: 10.1371/journal.pone.0180147. eCollection 2017.

8.

Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer.

Chellappa K, Deol P, Evans JR, Vuong LM, Chen G, Briançon N, Bolotin E, Lytle C, Nair MG, Sladek FM.

Elife. 2016 May 11;5. pii: e10903. doi: 10.7554/eLife.10903.

9.

Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.

Vuong LM, Chellappa K, Dhahbi JM, Deans JR, Fang B, Bolotin E, Titova NV, Hoverter NP, Spindler SR, Waterman ML, Sladek FM.

Mol Cell Biol. 2015 Oct;35(20):3471-90. doi: 10.1128/MCB.00030-15. Epub 2015 Aug 3.

10.

Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver.

Deol P, Evans JR, Dhahbi J, Chellappa K, Han DS, Spindler S, Sladek FM.

PLoS One. 2015 Jul 22;10(7):e0132672. doi: 10.1371/journal.pone.0132672. eCollection 2015.

11.

The yin and yang of proliferation and differentiation: cyclin D1 inhibits differentiation factors ChREBP and HNF4α.

Sladek FM.

Cell Cycle. 2012 Sep 1;11(17):3156-7. doi: 10.4161/cc.21721. Epub 2012 Aug 16. No abstract available.

12.

HNF4α: a new biomarker in colon cancer?

Chellappa K, Robertson GR, Sladek FM.

Biomark Med. 2012 Jun;6(3):297-300. doi: 10.2217/bmm.12.23. No abstract available.

13.

The transcription factor encyclopedia.

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperrière D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, Héligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW.

Genome Biol. 2012;13(3):R24. doi: 10.1186/gb-2012-13-3-r24.

14.

Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors.

Fang B, Mane-Padros D, Bolotin E, Jiang T, Sladek FM.

Nucleic Acids Res. 2012 Jul;40(12):5343-56. doi: 10.1093/nar/gks190. Epub 2012 Mar 1.

15.

Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer.

Chellappa K, Jankova L, Schnabl JM, Pan S, Brelivet Y, Fung CL, Chan C, Dent OF, Clarke SJ, Robertson GR, Sladek FM.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2302-7. doi: 10.1073/pnas.1106799109. Epub 2012 Jan 30.

16.

Nuclear receptor HNF4α binding sequences are widespread in Alu repeats.

Bolotin E, Chellappa K, Hwang-Verslues W, Schnabl JM, Yang C, Sladek FM.

BMC Genomics. 2011 Nov 15;12:560. doi: 10.1186/1471-2164-12-560.

17.

HNF4α--role in drug metabolism and potential drug target?

Hwang-Verslues WW, Sladek FM.

Curr Opin Pharmacol. 2010 Dec;10(6):698-705. doi: 10.1016/j.coph.2010.08.010. Review.

18.

What are nuclear receptor ligands?

Sladek FM.

Mol Cell Endocrinol. 2011 Mar 1;334(1-2):3-13. doi: 10.1016/j.mce.2010.06.018. Epub 2010 Jul 6. Review.

19.

Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays.

Bolotin E, Liao H, Ta TC, Yang C, Hwang-Verslues W, Evans JR, Jiang T, Sladek FM.

Hepatology. 2010 Feb;51(2):642-53. doi: 10.1002/hep.23357.

20.

Identification of an endogenous ligand bound to a native orphan nuclear receptor.

Yuan X, Ta TC, Lin M, Evans JR, Dong Y, Bolotin E, Sherman MA, Forman BM, Sladek FM.

PLoS One. 2009;4(5):e5609. doi: 10.1371/journal.pone.0005609. Epub 2009 May 19.

21.

Down-regulation of hepatic HNF4alpha gene expression during hyperinsulinemia via SREBPs.

Xie X, Liao H, Dang H, Pang W, Guan Y, Wang X, Shyy JY, Zhu Y, Sladek FM.

Mol Endocrinol. 2009 Apr;23(4):434-43. doi: 10.1210/me.2007-0531. Epub 2009 Jan 29.

22.

Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas.

Nammo T, Yamagata K, Tanaka T, Kodama T, Sladek FM, Fukui K, Katsube F, Sato Y, Miyagawa J, Shimomura I.

Gene Expr Patterns. 2008 Jan;8(2):96-106. Epub 2007 Oct 9.

PMID:
17996499
23.
24.

Phosphorylation of a conserved serine in the deoxyribonucleic acid binding domain of nuclear receptors alters intracellular localization.

Sun K, Montana V, Chellappa K, Brelivet Y, Moras D, Maeda Y, Parpura V, Paschal BM, Sladek FM.

Mol Endocrinol. 2007 Jun;21(6):1297-311. Epub 2007 Mar 27.

PMID:
17389749
25.

International Union of Pharmacology. LXVI. Orphan nuclear receptors.

Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, Muscat G, Perlmann T, Renaud JP, Schwabe J, Sladek F, Tsai MJ, Laudet V.

Pharmacol Rev. 2006 Dec;58(4):798-836. Review.

PMID:
17132856
26.
27.

Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene.

Maeda Y, Hwang-Verslues WW, Wei G, Fukazawa T, Durbin ML, Owen LB, Liu X, Sladek FM.

Biochem J. 2006 Dec 1;400(2):303-13.

28.

Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver.

Battle MA, Konopka G, Parviz F, Gaggl AL, Yang C, Sladek FM, Duncan SA.

Proc Natl Acad Sci U S A. 2006 May 30;103(22):8419-24. Epub 2006 May 19.

29.

Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon.

Garrison WD, Battle MA, Yang C, Kaestner KH, Sladek FM, Duncan SA.

Gastroenterology. 2006 Apr;130(4):1207-20.

30.

AMP-activated protein kinase is involved in endothelial NO synthase activation in response to shear stress.

Zhang Y, Lee TS, Kolb EM, Sun K, Lu X, Sladek FM, Kassab GS, Garland T Jr, Shyy JY.

Arterioscler Thromb Vasc Biol. 2006 Jun;26(6):1281-7. Epub 2006 Apr 6.

PMID:
16601232
31.

Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells.

Miura A, Yamagata K, Kakei M, Hatakeyama H, Takahashi N, Fukui K, Nammo T, Yoneda K, Inoue Y, Sladek FM, Magnuson MA, Kasai H, Miyagawa J, Gonzalez FJ, Shimomura I.

J Biol Chem. 2006 Feb 24;281(8):5246-57. Epub 2005 Dec 23.

32.

Functional characterization of the HNF4alpha isoform (HNF4alpha8) expressed in pancreatic beta-cells.

Ihara A, Yamagata K, Nammo T, Miura A, Yuan M, Tanaka T, Sladek FM, Matsuzawa Y, Miyagawa J, Shimomura I.

Biochem Biophys Res Commun. 2005 Apr 15;329(3):984-90.

PMID:
15752752
33.

Development of a cancer-targeted tissue-specific promoter system.

Fukazawa T, Maeda Y, Sladek FM, Owen-Schaub LB.

Cancer Res. 2004 Jan 1;64(1):363-9.

34.
35.

MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300.

Li QJ, Yang SH, Maeda Y, Sladek FM, Sharrocks AD, Martins-Green M.

EMBO J. 2003 Jan 15;22(2):281-91.

36.

Identifying transcription factor binding sites through Markov chain optimization.

Ellrott K, Yang C, Sladek FM, Jiang T.

Bioinformatics. 2002;18 Suppl 2:S100-9.

PMID:
12385991
38.

Desperately seeking...something.

Sladek F.

Mol Cell. 2002 Aug;10(2):219-21.

39.

Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205.

Maeda Y, Rachez C, Hawel L 3rd, Byus CV, Freedman LP, Sladek FM.

Mol Endocrinol. 2002 Jul;16(7):1502-10.

PMID:
12089346
40.
41.
42.

Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4 alpha in rat liver.

Wang B, Cai SR, Gao C, Sladek FM, Ponder KP.

Hepatology. 2001 Nov;34(5):979-89.

PMID:
11679969
43.

Novel nuclear target for thrombin: activation of the Elk1 transcription factor leads to chemokine gene expression.

Li QJ, Vaingankar S, Sladek FM, Martins-Green M.

Blood. 2000 Dec 1;96(12):3696-706.

PMID:
11090049
44.

Analysis of protein dimerization and ligand binding of orphan receptor HNF4alpha.

Bogan AA, Dallas-Yang Q, Ruse MD Jr, Maeda Y, Jiang G, Nepomuceno L, Scanlan TS, Cohen FE, Sladek FM.

J Mol Biol. 2000 Sep 29;302(4):831-51.

PMID:
10993727
45.
46.

Avoiding false positives in colony PCR.

Dallas-Yang Q, Jiang G, Sladek FM.

Biotechniques. 1998 Apr;24(4):580-2. No abstract available.

47.
48.
49.

Serine/threonine phosphorylation of orphan receptor hepatocyte nuclear factor 4.

Jiang G, Nepomuceno L, Yang Q, Sladek FM.

Arch Biochem Biophys. 1997 Apr 1;340(1):1-9.

PMID:
9126270

Supplemental Content

Loading ...
Support Center