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Items: 31


Utilizing Whole Fusobacterium Genomes To Identify, Correct, and Characterize Potential Virulence Protein Families.

Umaña A, Sanders BE, Yoo CC, Casasanta MA, Udayasuryan B, Verbridge SS, Slade DJ.

J Bacteriol. 2019 Nov 5;201(23). pii: e00273-19. doi: 10.1128/JB.00273-19. Print 2019 Dec 1.


Comparison of type 5d autotransporter phospholipases demonstrates a correlation between high activity and intracellular pathogenic lifestyle.

Trunk T, Casasanta MA, Yoo CC, Slade DJ, Leo JC.

Biochem J. 2019 Sep 24;476(18):2657-2676. doi: 10.1042/BCJ20190136.


Calcium Regulates the Nuclear Localization of Protein Arginine Deiminase 2.

Zheng L, Nagar M, Maurais AJ, Slade DJ, Parelkar SS, Coonrod SA, Weerapana E, Thompson PR.

Biochemistry. 2019 Jul 9;58(27):3042-3056. doi: 10.1021/acs.biochem.9b00225. Epub 2019 Jun 27.


Complete Genome Sequence of Fusobacterium necrophorum subsp. necrophorum ATCC 25286.

Umaña A, Lemkul JA, Slade DJ.

Microbiol Resour Announc. 2019 Feb 21;8(8). pii: e00025-19. doi: 10.1128/MRA.00025-19. eCollection 2019 Feb.


A Vector Suite for the Overexpression and Purification of Tagged Outer Membrane, Periplasmic, and Secreted Proteins in E. coli.

Casasanta MA, Slade DJ.

Methods Mol Biol. 2019;1960:123-138. doi: 10.1007/978-1-4939-9167-9_11.


Erratum for Sanders et al., "FusoPortal: an Interactive Repository of Hybrid MinION-Sequenced Fusobacterium Genomes Improves Gene Identification and Characterization".

Sanders BE, Umana A, Lemkul JA, Slade DJ.

mSphere. 2018 Jul 25;3(4). pii: e00379-18. doi: 10.1128/mSphere.00379-18. No abstract available.


Fusobacterium Genomics Using MinION and Illumina Sequencing Enables Genome Completion and Correction.

Todd SM, Settlage RE, Lahmers KK, Slade DJ.

mSphere. 2018 Jul 5;3(4). pii: e00269-18. doi: 10.1128/mSphere.00269-18.


FusoPortal: an Interactive Repository of Hybrid MinION-Sequenced Fusobacterium Genomes Improves Gene Identification and Characterization.

Sanders BE, Umana A, Lemkul JA, Slade DJ.

mSphere. 2018 Jul 5;3(4). pii: e00228-18. doi: 10.1128/mSphere.00228-18. Erratum in: mSphere. 2018 Jul 25;3(4):.


Biological Studies and Target Engagement of the 2- C-Methyl-d-Erythritol 4-Phosphate Cytidylyltransferase (IspD)-Targeting Antimalarial Agent (1 R,3 S)-MMV008138 and Analogs.

Ghavami M, Merino EF, Yao ZK, Elahi R, Simpson ME, Fernández-Murga ML, Butler JH, Casasanta MA, Krai PM, Totrov MM, Slade DJ, Carlier PR, Cassera MB.

ACS Infect Dis. 2018 Apr 13;4(4):549-559. doi: 10.1021/acsinfecdis.7b00159. Epub 2017 Nov 7.


A chemical and biological toolbox for Type Vd secretion: Characterization of the phospholipase A1 autotransporter FplA from Fusobacterium nucleatum.

Casasanta MA, Yoo CC, Smith HB, Duncan AJ, Cochrane K, Varano AC, Allen-Vercoe E, Slade DJ.

J Biol Chem. 2017 Dec 8;292(49):20240-20254. doi: 10.1074/jbc.M117.819144. Epub 2017 Oct 11.


N-(3-oxododecanoyl)-L-homoserine lactone interactions in the breast tumor microenvironment: Implications for breast cancer viability and proliferation in vitro.

Balhouse BN, Patterson L, Schmelz EM, Slade DJ, Verbridge SS.

PLoS One. 2017 Jul 10;12(7):e0180372. doi: 10.1371/journal.pone.0180372. eCollection 2017.


Enhanced Mucosal Defense and Reduced Tumor Burden in Mice with the Compromised Negative Regulator IRAK-M.

Rothschild DE, Zhang Y, Diao N, Lee CK, Chen K, Caswell CC, Slade DJ, Helm RF, LeRoith T, Li L, Allen IC.

EBioMedicine. 2017 Feb;15:36-47. doi: 10.1016/j.ebiom.2016.11.039. Epub 2016 Dec 3.


Chemical Proteomic Platform To Identify Citrullinated Proteins.

Lewallen DM, Bicker KL, Subramanian V, Clancy KW, Slade DJ, Martell J, Dreyton CJ, Sokolove J, Weerapana E, Thompson PR.

ACS Chem Biol. 2015 Nov 20;10(11):2520-8. doi: 10.1021/acschembio.5b00438. Epub 2015 Sep 23.


Slowed Diffusion and Excluded Volume Both Contribute to the Effects of Macromolecular Crowding on Alcohol Dehydrogenase Steady-State Kinetics.

Schneider SH, Lockwood SP, Hargreaves DI, Slade DJ, LoConte MA, Logan BE, McLaughlin EE, Conroy MJ, Slade KM.

Biochemistry. 2015 Sep 29;54(38):5898-906. doi: 10.1021/acs.biochem.5b00533. Epub 2015 Sep 16.


Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

Lewis HD, Liddle J, Coote JE, Atkinson SJ, Barker MD, Bax BD, Bicker KL, Bingham RP, Campbell M, Chen YH, Chung CW, Craggs PD, Davis RP, Eberhard D, Joberty G, Lind KE, Locke K, Maller C, Martinod K, Patten C, Polyakova O, Rise CE, Rüdiger M, Sheppard RJ, Slade DJ, Thomas P, Thorpe J, Yao G, Drewes G, Wagner DD, Thompson PR, Prinjha RK, Wilson DM.

Nat Chem Biol. 2015 Mar;11(3):189-91. doi: 10.1038/nchembio.1735. Epub 2015 Jan 26.


Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.

Slade DJ, Fang P, Dreyton CJ, Zhang Y, Fuhrmann J, Rempel D, Bax BD, Coonrod SA, Lewis HD, Guo M, Gross ML, Thompson PR.

ACS Chem Biol. 2015 Apr 17;10(4):1043-53. doi: 10.1021/cb500933j. Epub 2015 Jan 26.


A novel role for protein arginine deiminase 4 in pluripotency: the emerging role of citrullinated histone H1 in cellular programming.

Slade DJ, Horibata S, Coonrod SA, Thompson PR.

Bioessays. 2014 Aug;36(8):736-40. doi: 10.1002/bies.201400057. Epub 2014 May 30.


Pluripotency: citrullination unravels stem cells.

Slade DJ, Subramanian V, Thompson PR.

Nat Chem Biol. 2014 May;10(5):327-8. doi: 10.1038/nchembio.1504. No abstract available.


Chemical and biological methods to detect post-translational modifications of arginine.

Slade DJ, Subramanian V, Fuhrmann J, Thompson PR.

Biopolymers. 2014 Feb;101(2):133-43. doi: 10.1002/bip.22256. Review.


Activation of PAD4 in NET formation.

Rohrbach AS, Slade DJ, Thompson PR, Mowen KA.

Front Immunol. 2012 Nov 29;3:360. doi: 10.3389/fimmu.2012.00360. eCollection 2012.


Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation.

Zhang X, Bolt M, Guertin MJ, Chen W, Zhang S, Cherrington BD, Slade DJ, Dreyton CJ, Subramanian V, Bicker KL, Thompson PR, Mancini MA, Lis JT, Coonrod SA.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13331-6. doi: 10.1073/pnas.1203280109. Epub 2012 Aug 1.


Genetic reporter system for positioning of proteins at the bacterial pole.

Fixen KR, Janakiraman A, Garrity S, Slade DJ, Gray AN, Karahan N, Hochschild A, Goldberg MB.

MBio. 2012 Feb 28;3(2). pii: e00251-11. doi: 10.1128/mBio.00251-11. Print 2012.


Resolution of a proteinuric nephropathy associated with Babesia gibsoni infection in a dog.

Slade DJ, Lees GE, Berridge BR, Clubb FJ, Kuczynski LA, Littman MP.

J Am Anim Hosp Assoc. 2011 Nov-Dec;47(6):e138-44. doi: 10.5326/JAAHA-MS-5576.


Indazoles: regioselective protection and subsequent amine coupling reactions.

Slade DJ, Pelz NF, Bodnar W, Lampe JW, Watson PS.

J Org Chem. 2009 Aug 21;74(16):6331-4. doi: 10.1021/jo9006656.


Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit.

Slade DJ, Lovelace LL, Chruszcz M, Minor W, Lebioda L, Sodetz JM.

J Mol Biol. 2008 May 30;379(2):331-42. doi: 10.1016/j.jmb.2008.03.061. Epub 2008 Apr 3.


Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: implications for C8gamma ligand binding.

Lovelace LL, Chiswell B, Slade DJ, Sodetz JM, Lebioda L.

Mol Immunol. 2008 Feb;45(3):750-6. Epub 2007 Aug 9.


Binding of the lipocalin C8gamma to human complement protein C8alpha is mediated by loops located at the entrance to the C8gamma ligand binding site.

Chiswell B, Slade DJ, Sodetz JM.

Biochim Biophys Acta. 2006 Sep;1764(9):1518-24. Epub 2006 Jul 28.


Formal synthesis of 6-deoxyerythronolide B.

Crimmins MT, Slade DJ.

Org Lett. 2006 May 11;8(10):2191-4.


Airway remodeling from bench to bedside: current perspectives.

Slade DJ, Kraft M.

Clin Chest Med. 2006 Mar;27(1):71-85, vi. Review.


The fax-1 nuclear hormone receptor regulates axon pathfinding and neurotransmitter expression.

Much JW, Slade DJ, Klampert K, Garriga G, Wightman B.

Development. 2000 Feb;127(4):703-12.

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