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Items: 31

1.

The Immunogenicity in Mice of HCV Core Delivered as DNA Is Modulated by Its Capacity to Induce Oxidative Stress and Oxidative Stress Response.

Jansons J, Sominskaya I, Petrakova N, Starodubova ES, Smirnova OA, Alekseeva E, Bruvere R, Eliseeva O, Skrastina D, Kashuba E, Mihailova M, Kochetkov SN, Ivanov AV, Isaguliants MG.

Cells. 2019 Feb 28;8(3). pii: E208. doi: 10.3390/cells8030208.

2.

Synthesis and Immunological Evaluation of Virus-Like Particle-Milbemycin A₃/A₄ Conjugates.

Zeltins A, Turks M, Skrastina D, Lugiņina J, Kalnciema I, Balke I, Bizdēna Ē, Skrivelis V.

Antibiotics (Basel). 2017 Sep 11;6(3). pii: E18. doi: 10.3390/antibiotics6030018.

3.

Magnetic nanoparticles for efficient cell transduction with Semliki Forest virus.

Kurena B, Vežāne A, Skrastiņa D, Trofimova O, Zajakina A.

J Virol Methods. 2017 Jul;245:28-34. doi: 10.1016/j.jviromet.2017.03.008. Epub 2017 Mar 15.

PMID:
28315379
4.

Comparative protein profiling of B16 mouse melanoma cells susceptible and non-susceptible to alphavirus infection: Effect of the tumor microenvironment.

Vasilevska J, De Souza GA, Stensland M, Skrastina D, Zhulenvovs D, Paplausks R, Kurena B, Kozlovska T, Zajakina A.

Cancer Biol Ther. 2016 Oct 2;17(10):1035-1050. doi: 10.1080/15384047.2016.1219813. Epub 2016 Sep 16. Erratum in: Cancer Biol Ther. 2017 Jan 2;18(1):76.

5.

The Hepatitis B Virus Core Variants that Expose Foreign C-Terminal Insertions on the Outer Surface of Virus-Like Particles.

Dishlers A, Skrastina D, Renhofa R, Petrovskis I, Ose V, Lieknina I, Jansons J, Pumpens P, Sominskaya I.

Mol Biotechnol. 2015 Dec;57(11-12):1038-49. doi: 10.1007/s12033-015-9895-9.

6.

Potato Virus M-Like Nanoparticles: Construction and Characterization.

Kalnciema I, Balke I, Skrastina D, Ose V, Zeltins A.

Mol Biotechnol. 2015 Dec;57(11-12):982-92. doi: 10.1007/s12033-015-9891-0.

PMID:
26346833
7.

Silica nanoparticles as the adjuvant for the immunisation of mice using hepatitis B core virus-like particles.

Skrastina D, Petrovskis I, Lieknina I, Bogans J, Renhofa R, Ose V, Dishlers A, Dekhtyar Y, Pumpens P.

PLoS One. 2014 Dec 1;9(12):e114006. doi: 10.1371/journal.pone.0114006. eCollection 2014.

8.

Characterization of human adipose-derived stem cells cultured in autologous serum after subsequent passaging and long term cryopreservation.

Bogdanova A, Berzins U, Nikulshin S, Skrastina D, Ezerta A, Legzdina D, Kozlovska T.

J Stem Cells. 2014;9(3):135-48. doi: jsc.2014.9.3.135.

PMID:
25157448
9.

High efficiency of alphaviral gene transfer in combination with 5-fluorouracil in a mouse mammary tumor model.

Zajakina A, Vasilevska J, Zhulenkovs D, Skrastina D, Spaks A, Plotniece A, Kozlovska T.

BMC Cancer. 2014 Jun 20;14:460. doi: 10.1186/1471-2407-14-460.

10.

A VLP library of C-terminally truncated Hepatitis B core proteins: correlation of RNA encapsidation with a Th1/Th2 switch in the immune responses of mice.

Sominskaya I, Skrastina D, Petrovskis I, Dishlers A, Berza I, Mihailova M, Jansons J, Akopjana I, Stahovska I, Dreilina D, Ose V, Pumpens P.

PLoS One. 2013 Sep 23;8(9):e75938. doi: 10.1371/journal.pone.0075938. eCollection 2013.

11.

Chimeric derivatives of hepatitis B virus core particles carrying major epitopes of the rubella virus E1 glycoprotein.

Skrastina D, Petrovskis I, Petraityte R, Sominskaya I, Ose V, Lieknina I, Bogans J, Sasnauskas K, Pumpens P.

Clin Vaccine Immunol. 2013 Nov;20(11):1719-28. doi: 10.1128/CVI.00533-13. Epub 2013 Sep 4.

12.

Recombinant Semliki Forest virus vectors encoding hepatitis B virus small surface and pre-S1 antigens induce broadly reactive neutralizing antibodies.

Niedre-Otomere B, Bogdanova A, Skrastina D, Zajakina A, Bruvere R, Ose V, Gerlich WH, Garoff H, Pumpens P, Glebe D, Kozlovska T.

J Viral Hepat. 2012 Sep;19(9):664-73. doi: 10.1111/j.1365-2893.2012.01594.x. Epub 2012 May 17.

PMID:
22863271
13.

Semliki Forest virus biodistribution in tumor-free and 4T1 mammary tumor-bearing mice: a comparison of transgene delivery by recombinant virus particles and naked RNA replicon.

Vasilevska J, Skrastina D, Spunde K, Garoff H, Kozlovska T, Zajakina A.

Cancer Gene Ther. 2012 Aug;19(8):579-87. doi: 10.1038/cgt.2012.37. Epub 2012 Jun 22.

PMID:
22722377
14.

Potato virus Y-like particles as a new carrier for the presentation of foreign protein stretches.

Kalnciema I, Skrastina D, Ose V, Pumpens P, Zeltins A.

Mol Biotechnol. 2012 Oct;52(2):129-39. doi: 10.1007/s12033-011-9480-9.

PMID:
22167454
15.

N-terminal myristoylation-dependent masking of neutralizing epitopes in the preS1 attachment site of hepatitis B virus.

Bremer CM, Sominskaya I, Skrastina D, Pumpens P, El Wahed AA, Beutling U, Frank R, Fritz HJ, Hunsmann G, Gerlich WH, Glebe D.

J Hepatol. 2011 Jul;55(1):29-37. doi: 10.1016/j.jhep.2010.10.019. Epub 2010 Nov 28.

PMID:
21145866
16.

Construction and immunological evaluation of multivalent hepatitis B virus (HBV) core virus-like particles carrying HBV and HCV epitopes.

Sominskaya I, Skrastina D, Dislers A, Vasiljev D, Mihailova M, Ose V, Dreilina D, Pumpens P.

Clin Vaccine Immunol. 2010 Jun;17(6):1027-33. doi: 10.1128/CVI.00468-09. Epub 2010 Apr 21.

17.

Enhancement of the expression of HCV core gene does not enhance core-specific immune response in DNA immunization: advantages of the heterologous DNA prime, protein boost immunization regimen.

Alekseeva E, Sominskaya I, Skrastina D, Egorova I, Starodubova E, Kushners E, Mihailova M, Petrakova N, Bruvere R, Kozlovskaya T, Isaguliants M, Pumpens P.

Genet Vaccines Ther. 2009 Jun 8;7:7. doi: 10.1186/1479-0556-7-7.

18.

High immunogenicity of a hydrophilic component of the hepatitis B virus preS1 sequence exposed on the surface of three virus-like particle carriers.

Skrastina D, Bulavaite A, Sominskaya I, Kovalevska L, Ose V, Priede D, Pumpens P, Sasnauskas K.

Vaccine. 2008 Apr 7;26(16):1972-81. doi: 10.1016/j.vaccine.2008.02.030. Epub 2008 Feb 26.

PMID:
18343539
19.

Recombinant virus-like particles as a carrier of B- and T-cell epitopes of hepatitis C virus (HCV).

Mihailova M, Boos M, Petrovskis I, Ose V, Skrastina D, Fiedler M, Sominskaya I, Ross S, Pumpens P, Roggendorf M, Viazov S.

Vaccine. 2006 May 15;24(20):4369-77. Epub 2006 Mar 15.

PMID:
16574285
20.

Signal sequences modulate the immunogenic performance of human hepatitis C virus E2 gene.

Sominskaya I, Alekseeva E, Skrastina D, Mokhonov V, Starodubova E, Jansons J, Levi M, Prilipov A, Kozlovska T, Smirnov V, Pumpens P, Isaguliants MG.

Mol Immunol. 2006 May;43(12):1941-52. Epub 2006 Jan 25.

PMID:
16442623
21.

Assembly of bacteriophage Qbeta virus-like particles in yeast Saccharomyces cerevisiae and Pichia pastoris.

Freivalds J, Dislers A, Ose V, Skrastina D, Cielens I, Pumpens P, Sasnauskas K, Kazaks A.

J Biotechnol. 2006 May 29;123(3):297-303. Epub 2006 Jan 6.

PMID:
16406160
22.

A hantavirus nucleocapsid protein segment exposed on hepatitis B virus core particles is highly immunogenic in mice when applied without adjuvants or in the presence of pre-existing anti-core antibodies.

Geldmacher A, Skrastina D, Borisova G, Petrovskis I, Krüger DH, Pumpens P, Ulrich R.

Vaccine. 2005 Jun 10;23(30):3973-83. Epub 2005 Mar 16.

PMID:
15917119
23.

Mosaic hepatitis B virus core particles presenting the complete preS sequence of the viral envelope on their surface.

Kazaks A, Borisova G, Cvetkova S, Kovalevska L, Ose V, Sominskaya I, Pumpens P, Skrastina D, Dislers A.

J Gen Virol. 2004 Sep;85(Pt 9):2665-70.

PMID:
15302960
24.

An amino-terminal segment of hantavirus nucleocapsid protein presented on hepatitis B virus core particles induces a strong and highly cross-reactive antibody response in mice.

Geldmacher A, Skrastina D, Petrovskis I, Borisova G, Berriman JA, Roseman AM, Crowther RA, Fischer J, Musema S, Gelderblom HR, Lundkvist A, Renhofa R, Ose V, Krüger DH, Pumpens P, Ulrich R.

Virology. 2004 May 20;323(1):108-19.

25.

Stop codon insertion restores the particle formation ability of hepatitis B virus core-hantavirus nucleocapsid protein fusions.

Kazaks A, Lachmann S, Koletzki D, Petrovskis I, Dislers A, Ose V, Skrastina D, Gelderblom HR, Lundkvist A, Meisel H, Borisova G, Krüger DH, Pumpens P, Ulrich R.

Intervirology. 2002;45(4-6):340-9.

PMID:
12602354
26.

Chimeric bacteriophage fr virus-like particles harboring the immunodominant C-terminal region of hamster polyomavirus VP1 induce a strong VP1-specific antibody response in rabbits and mice.

Voronkova T, Grosch A, Kazaks A, Ose V, Skrastina D, Sasnauskas K, Jandrig B, Arnold W, Scherneck S, Pumpens P, Ulrich R.

Viral Immunol. 2002;15(4):627-43.

PMID:
12513932
27.

Evaluation of HBs, HBc, and frCP virus-like particles for expression of human papillomavirus 16 E7 oncoprotein epitopes.

Pumpens P, Razanskas R, Pushko P, Renhof R, Gusars I, Skrastina D, Ose V, Borisova G, Sominskaya I, Petrovskis I, Jansons J, Sasnauskas K.

Intervirology. 2002;45(1):24-32.

PMID:
11937768
28.

Behavior of a short preS1 epitope on the surface of hepatitis B core particles.

Borisova G, Borschukova O, Skrastina D, Dislers A, Ose V, Pumpens P, Grens E.

Biol Chem. 1999 Mar;380(3):315-24.

PMID:
10223334
29.

T cell-independent type I antibody response against B cell epitopes expressed repetitively on recombinant virus particles.

Fehr T, Skrastina D, Pumpens P, Zinkernagel RM.

Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9477-81.

30.

Spatial structure and insertion capacity of immunodominant region of hepatitis B core antigen.

Borisova G, Borschukova Wanst O, Mezule G, Skrastina D, Petrovskis I, Dislers A, Pumpens P, Grens E.

Intervirology. 1996;39(1-2):16-22. Review.

PMID:
8957665
31.

Hybrid hepatitis B virus nucleocapsid bearing an immunodominant region from hepatitis B virus surface antigen.

Borisova G, Arya B, Dislers A, Borschukova O, Tsibinogin V, Skrastina D, Eldarov MA, Pumpens P, Skryabin KG, Grens E.

J Virol. 1993 Jun;67(6):3696-701.

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