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Items: 16

1.

Signals Getting Crossed in the Entanglement of Redox and Phosphorylation Pathways: Phosphorylation of Peroxiredoxin Proteins Sparks Cell Signaling.

Skoko JJ, Attaran S, Neumann CA.

Antioxidants (Basel). 2019 Jan 23;8(2). pii: E29. doi: 10.3390/antiox8020029. Review.

2.

Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA-damaging agents on growth of triple-negative breast cells.

Asan A, Skoko JJ, Woodcock CC, Wingert BM, Woodcock SR, Normolle D, Huang Y, Stark JM, Camacho CJ, Freeman BA, Neumann CA.

J Biol Chem. 2019 Jan 11;294(2):397-404. doi: 10.1074/jbc.AC118.005899. Epub 2018 Nov 26.

PMID:
30478172
3.

Peroxiredoxin Involvement in the Initiation and Progression of Human Cancer.

Hampton MB, Vick KA, Skoko JJ, Neumann CA.

Antioxid Redox Signal. 2018 Mar 1;28(7):591-608. doi: 10.1089/ars.2017.7422. Epub 2018 Feb 1. Review.

PMID:
29237274
4.

A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7.

Hopkins BL, Nadler M, Skoko JJ, Bertomeu T, Pelosi A, Shafaei PM, Levine K, Schempf A, Pennarun B, Yang B, Datta D, Bucur O, Ndebele K, Oesterreich S, Yang D, Giulia Rizzo M, Khosravi-Far R, Neumann CA.

Antioxid Redox Signal. 2018 Jan 1;28(1):62-77. doi: 10.1089/ars.2016.6871. Epub 2017 May 1.

5.

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms.

Palliyaguru DL, Chartoumpekis DV, Wakabayashi N, Skoko JJ, Yagishita Y, Singh SV, Kensler TW.

Free Radic Biol Med. 2016 Dec;101:116-128. doi: 10.1016/j.freeradbiomed.2016.10.003. Epub 2016 Oct 4.

6.

Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet.

Slocum SL, Skoko JJ, Wakabayashi N, Aja S, Yamamoto M, Kensler TW, Chartoumpekis DV.

Arch Biochem Biophys. 2016 Feb 1;591:57-65. doi: 10.1016/j.abb.2015.11.040. Epub 2015 Dec 14.

7.

Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity.

Skoko JJ, Wakabayashi N, Noda K, Kimura S, Tobita K, Shigemura N, Tsujita T, Yamamoto M, Kensler TW.

Toxicol Sci. 2014 Sep;141(1):112-9. doi: 10.1093/toxsci/kfu109. Epub 2014 Jun 12.

8.

Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling.

Wakabayashi N, Skoko JJ, Chartoumpekis DV, Kimura S, Slocum SL, Noda K, Palliyaguru DL, Fujimuro M, Boley PA, Tanaka Y, Shigemura N, Biswal S, Yamamoto M, Kensler TW.

Mol Cell Biol. 2014 Feb;34(4):653-63. doi: 10.1128/MCB.01408-13. Epub 2013 Dec 2.

9.

When NRF2 talks, who's listening?

Wakabayashi N, Slocum SL, Skoko JJ, Shin S, Kensler TW.

Antioxid Redox Signal. 2010 Dec 1;13(11):1649-63. doi: 10.1089/ars.2010.3216. Epub 2010 Jul 9. Review.

10.

Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B.

Keinan S, Paquette WD, Skoko JJ, Beratan DN, Yang W, Shinde S, Johnston PA, Lazo JS, Wipf P.

Org Biomol Chem. 2008 Sep 21;6(18):3256-63. doi: 10.1039/b806712k. Epub 2008 Jul 15.

11.

A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells.

Vogt A, McDonald PR, Tamewitz A, Sikorski RP, Wipf P, Skoko JJ 3rd, Lazo JS.

Mol Cancer Ther. 2008 Feb;7(2):330-40. doi: 10.1158/1535-7163.MCT-07-2165. Epub 2008 Feb 1.

13.

Development and optimization of high-throughput in vitro protein phosphatase screening assays.

Tierno MB, Johnston PA, Foster C, Skoko JJ, Shinde SN, Shun TY, Lazo JS.

Nat Protoc. 2007;2(5):1134-44.

PMID:
17546004
14.

Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library.

Lazo JS, Skoko JJ, Werner S, Mitasev B, Bakan A, Koizumi F, Yellow-Duke A, Bahar I, Brummond KM.

J Pharmacol Exp Ther. 2007 Sep;322(3):940-7. Epub 2007 May 30.

PMID:
17538006
15.

Biological evaluation of newly synthesized quinoline-5,8-quinones as Cdc25B inhibitors.

Cossy J, Belotti D, Brisson M, Skoko JJ, Wipf P, Lazo JS.

Bioorg Med Chem. 2006 Sep 15;14(18):6283-7. Epub 2006 Jun 16.

PMID:
16782352
16.

Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1.

Lazo JS, Nunes R, Skoko JJ, Queiroz de Oliveira PE, Vogt A, Wipf P.

Bioorg Med Chem. 2006 Aug 15;14(16):5643-50. Epub 2006 May 15.

PMID:
16698271

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