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Items: 1 to 50 of 124

1.

Hydroxyphenylation of Histone Lysines: Post-translational Modification by Quinone Imines.

Ravindra KC, Trudel LJ, Wishnok JS, Wogan GN, Tannenbaum SR, Skipper PL.

ACS Chem Biol. 2016 May 20;11(5):1230-7. doi: 10.1021/acschembio.5b00923. Epub 2016 Feb 18.

2.

Protective effects of ascorbic acid against the genetic and epigenetic alterations induced by 3,5-dimethylaminophenol in AA8 cells.

Chao MW, Erkekoglu P, Tseng CY, Ye W, Trudel LJ, Skipper PL, Tannenbaum SR, Wogan GN.

J Appl Toxicol. 2015 May;35(5):466-77. doi: 10.1002/jat.3046. Epub 2014 Sep 1.

3.

Cytoplasmic and nuclear toxicity of 3,5-dimethylaminophenol and potential protection by selenocompounds.

Erkekoglu P, Chao MW, Ye W, Ge J, Trudel LJ, Skipper PL, Kocer-Gumusel B, Engelward BP, Wogan GN, Tannenbaum SR.

Food Chem Toxicol. 2014 Oct;72:98-110. doi: 10.1016/j.fct.2014.06.031. Epub 2014 Jul 9.

PMID:
25014158
4.

Intracellular generation of ROS by 3,5-dimethylaminophenol: persistence, cellular response, and impact of molecular toxicity.

Chao MW, Erkekoglu P, Tseng CY, Ye W, Trudel LJ, Skipper PL, Tannenbaum SR, Wogan GN.

Toxicol Sci. 2014 Sep;141(1):300-13. doi: 10.1093/toxsci/kfu127. Epub 2014 Jun 27.

5.

Single dose pharmacokinetics of oral tenofovir in plasma, peripheral blood mononuclear cells, colonic tissue, and vaginal tissue.

Louissaint NA, Cao YJ, Skipper PL, Liberman RG, Tannenbaum SR, Nimmagadda S, Anderson JR, Everts S, Bakshi R, Fuchs EJ, Hendrix CW.

AIDS Res Hum Retroviruses. 2013 Nov;29(11):1443-50. doi: 10.1089/AID.2013.0044. Epub 2013 May 29.

6.

Transimination of quinone imines: a mechanism for embedding exogenous redox activity into the nucleosome.

Ye W, Seneviratne UI, Chao MW, Ravindra KC, Wogan GN, Tannenbaum SR, Skipper PL.

Chem Res Toxicol. 2012 Dec 17;25(12):2627-9. doi: 10.1021/tx3004517. Epub 2012 Dec 3.

7.

Biphasic elimination of tenofovir diphosphate and nonlinear pharmacokinetics of zidovudine triphosphate in a microdosing study.

Chen J, Flexner C, Liberman RG, Skipper PL, Louissaint NA, Tannenbaum SR, Hendrix CW, Fuchs EJ.

J Acquir Immune Defic Syndr. 2012 Dec 15;61(5):593-9. doi: 10.1097/QAI.0b013e3182717c98.

8.

Genotoxicity of 2,6- and 3,5-dimethylaniline in cultured mammalian cells: the role of reactive oxygen species.

Chao MW, Kim MY, Ye W, Ge J, Trudel LJ, Belanger CL, Skipper PL, Engelward BP, Tannenbaum SR, Wogan GN.

Toxicol Sci. 2012 Nov;130(1):48-59. doi: 10.1093/toxsci/kfs229. Epub 2012 Jul 24.

9.

N7-glycidamide-guanine DNA adduct formation by orally ingested acrylamide in rats: a dose-response study encompassing human diet-related exposure levels.

Watzek N, Böhm N, Feld J, Scherbl D, Berger F, Merz KH, Lampen A, Reemtsma T, Tannenbaum SR, Skipper PL, Baum M, Richling E, Eisenbrand G.

Chem Res Toxicol. 2012 Feb 20;25(2):381-90. doi: 10.1021/tx200446z. Epub 2012 Jan 31.

PMID:
22211389
10.

Cytochrome P450-mediated metabolism and DNA binding of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline and its carcinogenic isomer 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in mice.

Turesky RJ, Bessette EE, Dunbar D, Liberman RG, Skipper PL.

Chem Res Toxicol. 2012 Feb 20;25(2):410-21. doi: 10.1021/tx2004536. Epub 2011 Dec 28.

11.

Lycopene bioavailability and metabolism in humans: an accelerator mass spectrometry study.

Ross AB, Vuong le T, Ruckle J, Synal HA, Schulze-König T, Wertz K, Rümbeli R, Liberman RG, Skipper PL, Tannenbaum SR, Bourgeois A, Guy PA, Enslen M, Nielsen IL, Kochhar S, Richelle M, Fay LB, Williamson G.

Am J Clin Nutr. 2011 Jun;93(6):1263-73. doi: 10.3945/ajcn.110.008375. Epub 2011 May 4.

PMID:
21543537
12.

BEAMS Lab at MIT: Status report.

Liberman RG, Skipper PL, Tannenbaum SR.

Nucl Instrum Methods Phys Res B. 2010 Apr 1;263(7-8):887-890.

13.

Monocyclic aromatic amines as potential human carcinogens: old is new again.

Skipper PL, Kim MY, Sun HL, Wogan GN, Tannenbaum SR.

Carcinogenesis. 2010 Jan;31(1):50-8. doi: 10.1093/carcin/bgp267. Epub 2009 Nov 3. Review.

14.

Are the new oral anticoagulant agents easy to use? Report from an orthopaedic ward.

Turner LL, Lovell M, Skipper P, Shiach CR.

Br J Haematol. 2009 Aug;146(4):461-4. doi: 10.1111/j.1365-2141.2009.07801.x. Epub 2009 Jul 9. No abstract available.

PMID:
19604231
15.

An assay for botulinum toxin types A, B and F that requires both functional binding and catalytic activities within the neurotoxin.

Evans ER, Skipper PJ, Shone CC.

J Appl Microbiol. 2009 Oct;107(4):1384-91. doi: 10.1111/j.1365-2672.2009.04325.x. Epub 2009 Apr 22.

16.

Integration of continuous-flow accelerator mass spectrometry with chromatography and mass-selective detection.

Flarakos J, Liberman RG, Tannenbaum SR, Skipper PL.

Anal Chem. 2008 Jul 1;80(13):5079-85. doi: 10.1021/ac800286g. Epub 2008 May 22.

PMID:
18494504
17.

Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin-10(3H)-one}, by accelerator mass spectrometry.

Knutson CG, Skipper PL, Liberman RG, Tannenbaum SR, Marnett LJ.

Chem Res Toxicol. 2008 Jun;21(6):1290-4. doi: 10.1021/tx800049v. Epub 2008 May 8.

18.

Identification of adducts formed by reaction of N-acetoxy-3,5-dimethylaniline with DNA.

Cui L, Sun HL, Wishnok JS, Tannenbaum SR, Skipper PL.

Chem Res Toxicol. 2007 Nov;20(11):1730-6.

19.
20.

Environmental tobacco smoke and bladder cancer risk in never smokers of Los Angeles County.

Jiang X, Yuan JM, Skipper PL, Tannenbaum SR, Yu MC.

Cancer Res. 2007 Aug 1;67(15):7540-5.

21.

Application of liquid chromatography-accelerator mass spectrometry (LC-AMS) to evaluate the metabolic profiles of a drug candidate in human urine and plasma.

Prakash C, Shaffer CL, Tremaine LM, Liberman RG, Skipper PL, Flarakos J, Tannenbaum SR.

Drug Metab Lett. 2007 Aug;1(3):226-31.

PMID:
19356047
22.
23.

Detection and quantification of 4-ABP adducts in DNA from bladder cancer patients.

Zayas B, Stillwell SW, Wishnok JS, Trudel LJ, Skipper P, Yu MC, Tannenbaum SR, Wogan GN.

Carcinogenesis. 2007 Feb;28(2):342-9. Epub 2006 Aug 21.

PMID:
16926175
24.

DNA adduct formation by 2,6-dimethyl-, 3,5-dimethyl-, and 3-ethylaniline in vivo in mice.

Skipper PL, Trudel LJ, Kensler TW, Groopman JD, Egner PA, Liberman RG, Wogan GN, Tannenbaum SR.

Chem Res Toxicol. 2006 Aug;19(8):1086-90.

PMID:
16918249
25.

DNA adducts formed by a novel antitumor agent 11beta-dichloro in vitro and in vivo.

Hillier SM, Marquis JC, Zayas B, Wishnok JS, Liberman RG, Skipper PL, Tannenbaum SR, Essigmann JM, Croy RG.

Mol Cancer Ther. 2006 Apr;5(4):977-84.

26.

Quantification of DNA strand breaks and abasic sites by oxime derivatization and accelerator mass spectrometry: application to gamma-radiation and peroxynitrite.

Zhou X, Liberman RG, Skipper PL, Margolin Y, Tannenbaum SR, Dedon PC.

Anal Biochem. 2005 Aug 1;343(1):84-92.

PMID:
15964542
27.

Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450.

Choi MH, Skipper PL, Wishnok JS, Tannenbaum SR.

Drug Metab Dispos. 2005 Jun;33(6):714-8. Epub 2005 Mar 11.

PMID:
15764715
28.

Alkylaniline-hemoglobin adducts and risk of non-smoking-related bladder cancer.

Gan J, Skipper PL, Gago-Dominguez M, Arakawa K, Ross RK, Yu MC, Tannenbaum SR.

J Natl Cancer Inst. 2004 Oct 6;96(19):1425-31.

PMID:
15467031
29.

Carotenoids/vitamin C and smoking-related bladder cancer.

Castelao JE, Yuan JM, Gago-Dominguez M, Skipper PL, Tannenbaum SR, Chan KK, Watson MA, Bell DA, Coetzee GA, Ross RK, Yu MC.

Int J Cancer. 2004 Jun 20;110(3):417-23.

30.

An interface for direct analysis of (14)c in nonvolatile samples by accelerator mass spectrometry.

Liberman RG, Tannenbaum SR, Hughey BJ, Shefer RE, Klinkowstein RE, Prakash C, Harriman SP, Skipper PL.

Anal Chem. 2004 Jan 15;76(2):328-34.

PMID:
14719879
31.

Nonsmoking-related arylamine exposure and bladder cancer risk.

Skipper PL, Tannenbaum SR, Ross RK, Yu MC.

Cancer Epidemiol Biomarkers Prev. 2003 Jun;12(6):503-7.

32.

Precision and sensitivity of aminobiphenyl hemoglobin adduct assays in a long-term population study.

Skipper PL.

J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Oct 5;778(1-2):375-81.

PMID:
12376142
33.

Arylamine exposures and bladder cancer risk.

Yu MC, Skipper PL, Tannenbaum SR, Chan KK, Ross RK.

Mutat Res. 2002 Sep 30;506-507:21-8. Review.

PMID:
12351141
34.

Oxidation of 2,6-dimethylaniline by recombinant human cytochrome P450s and human liver microsomes.

Gan J, Skipper PL, Tannenbaum SR.

Chem Res Toxicol. 2001 Jun;14(6):672-7.

PMID:
11409937
35.

Site-selective nitration of tyrosine in human serum albumin by peroxynitrite.

Jiao K, Mandapati S, Skipper PL, Tannenbaum SR, Wishnok JS.

Anal Biochem. 2001 Jun 1;293(1):43-52.

PMID:
11373077
36.

Gender- and smoking-related bladder cancer risk.

Castelao JE, Yuan JM, Skipper PL, Tannenbaum SR, Gago-Dominguez M, Crowder JS, Ross RK, Yu MC.

J Natl Cancer Inst. 2001 Apr 4;93(7):538-45.

PMID:
11287448
37.
38.

N-acetyltransferase 2 phenotype but not NAT1*10 genotype affects aminobiphenyl-hemoglobin adduct levels.

Probst-Hensch NM, Bell DA, Watson MA, Skipper PL, Tannenbaum SR, Chan KK, Ross RK, Yu MC.

Cancer Epidemiol Biomarkers Prev. 2000 Jun;9(6):619-23.

39.

Biomonitoring of heterocyclic aromatic amine metabolites in human urine.

Stillwell WG, Turesky RJ, Sinha R, Skipper PL, Tannenbaum SR.

Cancer Lett. 1999 Sep 1;143(2):145-8.

PMID:
10503894
40.

DNA adduct formation by secondary metabolites of cyclopenta[cd]pyrene in vitro.

Hsu CH, Skipper PL, Tannenbaum SR.

Cancer Lett. 1999 Mar 1;136(2):137-41.

PMID:
10355742
41.

Urinary excretion of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in White, African-American, and Asian-American men in Los Angeles County.

Kidd LC, Stillwell WG, Yu MC, Wishnok JS, Skipper PL, Ross RK, Henderson BE, Tannenbaum SR.

Cancer Epidemiol Biomarkers Prev. 1999 May;8(5):439-45.

42.

Molecular and genetic damage from environmental tobacco smoke in young children.

Tang D, Warburton D, Tannenbaum SR, Skipper P, Santella RM, Cereijido GS, Crawford FG, Perera FP.

Cancer Epidemiol Biomarkers Prev. 1999 May;8(5):427-31.

43.

Identification of subdomain IB in human serum albumin as a major binding site for polycyclic aromatic hydrocarbon epoxides.

Brunmark P, Harriman S, Skipper PL, Wishnok JS, Amin S, Tannenbaum SR.

Chem Res Toxicol. 1997 Aug;10(8):880-6.

PMID:
9282837
44.

Characterization of DNA adducts formed by cyclopenta[cd]pyrene epoxide.

Hsu CH, Skipper PL, Harris TM, Tannenbaum SR.

Chem Res Toxicol. 1997 Feb;10(2):248-53.

PMID:
9049438
45.

Cytochrome P4501A2: enzyme induction and genetic control in determining 4-aminobiphenyl-hemoglobin adduct levels.

Landi MT, Zocchetti C, Bernucci I, Kadlubar FF, Tannenbaum S, Skipper P, Bartsch H, Malaveille C, Shields P, Caporaso NE, Vineis P.

Cancer Epidemiol Biomarkers Prev. 1996 Sep;5(9):693-8.

46.

Influence of tertiary structure on nucleophilic substitution reactions of proteins.

Skipper PL.

Chem Res Toxicol. 1996 Sep;9(6):918-23. Review. No abstract available.

PMID:
8870977
47.

Glutathione S-transferase M1 genotype affects aminobiphenyl-hemoglobin adduct levels in white, black and Asian smokers and nonsmokers.

Yu MC, Ross RK, Chan KK, Henderson BE, Skipper PL, Tannenbaum SR, Coetzee GA.

Cancer Epidemiol Biomarkers Prev. 1995 Dec;4(8):861-4.

48.

Lysine adducts between methyltetrahydrophthalic anhydride and collagen in guinea pig lung.

Jönsson BA, Wishnok JS, Skipper PL, Stillwell WG, Tannenbaum SR.

Toxicol Appl Pharmacol. 1995 Nov;135(1):156-62.

PMID:
7482535
49.

Altered aromatic amine metabolism in epileptic patients treated with phenobarbital.

Wallin H, Skipper PL, Tannenbaum SR, Jensen JP, Rylander L, Olsen JH.

Cancer Epidemiol Biomarkers Prev. 1995 Oct-Nov;4(7):771-3.

50.

MeIQx (2-amino-3,8-dimethylimidazo [4,5-f]quinoxaline): metabolism in humans and urinary metabolites in human populations.

Tannenbaum SR, Stillwell WG, Ji H, Skipper PL, Yu MC, Ross RK, Henderson BE, Turesky RJ, Gross GA.

Princess Takamatsu Symp. 1995;23:197-206.

PMID:
8844811

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