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The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques.

Webb GM, Molden J, Busman-Sahay K, Abdulhaqq S, Wu HL, Weber WC, Bateman KB, Reed JS, Northrup M, Maier N, Tanaka S, Gao L, Davey B, Carpenter BL, Axthelm MK, Stanton JJ, Smedley J, Greene JM, Safrit JT, Estes JD, Skinner PJ, Sacha JB.

PLoS Pathog. 2020 Mar 12;16(3):e1008339. doi: 10.1371/journal.ppat.1008339. eCollection 2020 Mar.


Transmission dynamics between infected waterfowl and terrestrial poultry: Differences between the transmission and tropism of H5N8 highly pathogenic avian influenza virus (clade among ducks, chickens and turkeys.

Puranik A, Slomka MJ, Warren CJ, Thomas SS, Mahmood S, Byrne AMP, Ramsay AM, Skinner P, Watson S, Everett HE, Núñez A, Brown IH, Brookes SM.

Virology. 2020 Feb;541:113-123. doi: 10.1016/j.virol.2019.10.014. Epub 2019 Oct 31.


Need for Bioequivalence Standards that Reflect the Clinical Importance of the Complex Pharmacokinetics of Paliperidone Palmitate Long-Acting Injectable Suspension.

Procyshyn RM, Lamoure JW, Katzman MA, Skinner PL, Sherman SE.

J Pharm Pharm Sci. 2019;22(1):548-566. doi: 10.18433/jpps30669.


Rapid Transduction and Expansion of Transduced T Cells with Maintenance of Central Memory Populations.

Pampusch MS, Haran KP, Hart GT, Rakasz EG, Rendahl AK, Berger EA, Connick E, Skinner PJ.

Mol Ther Methods Clin Dev. 2019 Sep 30;16:1-10. doi: 10.1016/j.omtm.2019.09.007. eCollection 2020 Mar 13.


Detection of Antigen-Specific T Cells Using In Situ MHC Tetramer Staining.

Abdelaal HM, Cartwright EK, Skinner PJ.

Int J Mol Sci. 2019 Oct 18;20(20). pii: E5165. doi: 10.3390/ijms20205165. Review.


Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection.

Li S, Folkvord JM, Kovacs KJ, Wagstaff RK, Mwakalundwa G, Rendahl AK, Rakasz EG, Connick E, Skinner PJ.

PLoS Pathog. 2019 Mar 21;15(3):e1007311. doi: 10.1371/journal.ppat.1007311. eCollection 2019 Mar.


Extended Treatment with Glial Cell Line-Derived Neurotrophic Factor in Parkinson's Disease.

Whone AL, Boca M, Luz M, Woolley M, Mooney L, Dharia S, Broadfoot J, Cronin D, Schroers C, Barua NU, Longpre L, Barclay CL, Boiko C, Johnson GA, Fibiger HC, Harrison R, Lewis O, Pritchard G, Howell M, Irving C, Johnson D, Kinch S, Marshall C, Lawrence AD, Blinder S, Sossi V, Stoessl AJ, Skinner P, Mohr E, Gill SS.

J Parkinsons Dis. 2019;9(2):301-313. doi: 10.3233/JPD-191576.


Randomized trial of intermittent intraputamenal glial cell line-derived neurotrophic factor in Parkinson's disease.

Whone A, Luz M, Boca M, Woolley M, Mooney L, Dharia S, Broadfoot J, Cronin D, Schroers C, Barua NU, Longpre L, Barclay CL, Boiko C, Johnson GA, Fibiger HC, Harrison R, Lewis O, Pritchard G, Howell M, Irving C, Johnson D, Kinch S, Marshall C, Lawrence AD, Blinder S, Sossi V, Stoessl AJ, Skinner P, Mohr E, Gill SS.

Brain. 2019 Mar 1;142(3):512-525. doi: 10.1093/brain/awz023.


Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques.

Wodarz D, Skinner PJ, Levy DN, Connick E.

PLoS Comput Biol. 2018 Oct 18;14(10):e1006461. doi: 10.1371/journal.pcbi.1006461. eCollection 2018 Oct.


Managing a Colonoscopic Perforation in a Patient with No Abdominal Wall.

George J, Peirson M, Birks S, Skinner P.

Case Rep Surg. 2018 Jul 10;2018:7175381. doi: 10.1155/2018/7175381. eCollection 2018.


Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T Cells Engineered to Target B Cell Follicles and Suppress SIV Replication.

Haran KP, Hajduczki A, Pampusch MS, Mwakalundwa G, Vargas-Inchaustegui DA, Rakasz EG, Connick E, Berger EA, Skinner PJ.

Front Immunol. 2018 Mar 20;9:492. doi: 10.3389/fimmu.2018.00492. eCollection 2018.


The B-Cell Follicle in HIV Infection: Barrier to a Cure.

Bronnimann MP, Skinner PJ, Connick E.

Front Immunol. 2018 Jan 25;9:20. doi: 10.3389/fimmu.2018.00020. eCollection 2018. Review.


Drought will not leave your glass empty: Low risk of hydraulic failure revealed by long-term drought observations in world's top wine regions.

Charrier G, Delzon S, Domec JC, Zhang L, Delmas CEL, Merlin I, Corso D, King A, Ojeda H, Ollat N, Prieto JA, Scholach T, Skinner P, van Leeuwen C, Gambetta GA.

Sci Adv. 2018 Jan 31;4(1):eaao6969. doi: 10.1126/sciadv.aao6969. eCollection 2018 Jan.


The human IL-15 superagonist ALT-803 directs SIV-specific CD8+ T cells into B-cell follicles.

Webb GM, Li S, Mwakalundwa G, Folkvord JM, Greene JM, Reed JS, Stanton JJ, Legasse AW, Hobbs T, Martin LD, Park BS, Whitney JB, Jeng EK, Wong HC, Nixon DF, Jones RB, Connick E, Skinner PJ, Sacha JB.

Blood Adv. 2018 Jan 23;2(2):76-84. doi: 10.1182/bloodadvances.2017012971.


Detection of HIV-1-specific gastrointestinal tissue resident CD8+ T-cells in chronic infection.

Kiniry BE, Li S, Ganesh A, Hunt PW, Somsouk M, Skinner PJ, Deeks SG, Shacklett BL.

Mucosal Immunol. 2018 May;11(3):909-920. doi: 10.1038/mi.2017.96. Epub 2017 Nov 15.


Ultrasound-Assisted Removal of A Fishbone Stuck in A Tongue in the Emergency Department.

Kanon D, Skinner P, Kennedy WA 3rd, Cirilli AR.

J Emerg Med. 2017 May;52(5):e175-e177. doi: 10.1016/j.jemermed.2017.01.002. Epub 2017 Feb 28.


Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection.

Mylvaganam GH, Rios D, Abdelaal HM, Iyer S, Tharp G, Mavigner M, Hicks S, Chahroudi A, Ahmed R, Bosinger SE, Williams IR, Skinner PJ, Velu V, Amara RR.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1976-1981. doi: 10.1073/pnas.1621418114. Epub 2017 Feb 3. Erratum in: Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):E3366. Mavinger, Maud [corrected to Mavigner, Maud].


Simian Immunodeficiency Virus-Producing Cells in Follicles Are Partially Suppressed by CD8+ Cells In Vivo.

Li S, Folkvord JM, Rakasz EG, Abdelaal HM, Wagstaff RK, Kovacs KJ, Kim HO, Sawahata R, MaWhinney S, Masopust D, Connick E, Skinner PJ.

J Virol. 2016 Nov 28;90(24):11168-11180. Print 2016 Dec 15.


Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection.

Miles B, Miller SM, Folkvord JM, Levy DN, Rakasz EG, Skinner PJ, Connick E.

PLoS Pathog. 2016 Oct 7;12(10):e1005924. doi: 10.1371/journal.ppat.1005924. eCollection 2016 Oct.


Visible Prowess?: Reading Men’s Head and Face Wounds in Early Medieval Europe to 1000 CE.

Skinner P.

In: Tracy L, DeVries K, editors. Wounds and Wound Repair in Medieval Culture. Leiden (NL): Brill; 2015 Oct. Chapter 3.


Potential approaches for heterologous prion protein treatment of prion diseases.

Seelig DM, Goodman PA, Skinner PJ.

Prion. 2016;10(1):18-24. doi: 10.1080/19336896.2015.1123372.


Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection.

Miles B, Miller SM, Folkvord JM, Kimball A, Chamanian M, Meditz AL, Arends T, McCarter MD, Levy DN, Rakasz EG, Skinner PJ, Connick E.

Nat Commun. 2015 Oct 20;6:8608. doi: 10.1038/ncomms9608.


Marking the Face, Curing the Soul? Reading the Disfigurement of Women in the Later Middle Ages.

Skinner P.

In: Yoshikawa NK, editor. Medicine, Religion and Gender in Medieval Culture [Internet]. Suffolk (UK): Boydell & Brewer; 2015. Chapter 9.


Treatment of Prion Disease with Heterologous Prion Proteins.

Skinner PJ, Kim HO, Bryant D, Kinzel NJ, Reilly C, Priola SA, Ward AE, Goodman PA, Olson K, Seelig DM.

PLoS One. 2015 Jul 2;10(7):e0131993. doi: 10.1371/journal.pone.0131993. eCollection 2015.


In Situ Peptide-MHC-II Tetramer Staining of Antigen-Specific CD4+ T Cells in Tissues.

Dileepan T, Kim HO, Cleary PP, Skinner PJ.

PLoS One. 2015 Jun 11;10(6):e0128862. doi: 10.1371/journal.pone.0128862. eCollection 2015.


Loan program makes care more affordable.

Davidson D, Skinner P.

Revenue-cycle Strateg. 2015 Mar;12(2):5-6. No abstract available.


Comparison of Vibratome and Compresstome sectioning of fresh primate lymphoid and genital tissues for in situ MHC-tetramer and immunofluorescence staining.

Abdelaal HM, Kim HO, Wagstaff R, Sawahata R, Southern PJ, Skinner PJ.

Biol Proced Online. 2015 Jan 7;17(1):2. doi: 10.1186/s12575-014-0012-4. eCollection 2015.


Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL.

Connick E, Folkvord JM, Lind KT, Rakasz EG, Miles B, Wilson NA, Santiago ML, Schmitt K, Stephens EB, Kim HO, Wagstaff R, Li S, Abdelaal HM, Kemp N, Watkins DI, MaWhinney S, Skinner PJ.

J Immunol. 2014 Dec 1;193(11):5613-25. doi: 10.4049/jimmunol.1401161. Epub 2014 Oct 31.


Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry.

Li Q, Zeng M, Duan L, Voss JE, Smith AJ, Pambuccian S, Shang L, Wietgrefe S, Southern PJ, Reilly CS, Skinner PJ, Zupancic ML, Carlis JV, Piatak M Jr, Waterman D, Reeves RK, Masek-Hammerman K, Derdeyn CA, Alpert MD, Evans DT, Kohler H, Müller S, Robinson J, Lifson JD, Burton DR, Johnson RP, Haase AT.

J Immunol. 2014 Sep 15;193(6):3113-25. doi: 10.4049/jimmunol.1400820. Epub 2014 Aug 18.


Location and dynamics of the immunodominant CD8 T cell response to SIVΔnef immunization and SIVmac251 vaginal challenge.

Sasikala-Appukuttan AK, Kim HO, Kinzel NJ, Hong JJ, Smith AJ, Wagstaff R, Reilly C, Piatak M Jr, Lifson JD, Reeves RK, Johnson RP, Haase AT, Skinner PJ.

PLoS One. 2013 Dec 9;8(12):e81623. doi: 10.1371/journal.pone.0081623. eCollection 2013.


Intermittent convection-enhanced delivery to the brain through a novel transcutaneous bone-anchored port.

Barua NU, Woolley M, Bienemann AS, Johnson DE, Lewis O, Wyatt MJ, Irving C, O'Sullivan S, Murray G, Fennelly C, Skinner P, Gill SS.

J Neurosci Methods. 2013 Apr 15;214(2):223-32. doi: 10.1016/j.jneumeth.2013.02.007. Epub 2013 Feb 16.


(1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903): a potent GPR109a agonist that lowers free fatty acids in humans.

Boatman PD, Lauring B, Schrader TO, Kasem M, Johnson BR, Skinner P, Jung JK, Xu J, Cherrier MC, Webb PJ, Semple G, Sage CR, Knudsen J, Chen R, Luo WL, Caro L, Cote J, Lai E, Wagner J, Taggart AK, Carballo-Jane E, Hammond M, Colletti SL, Tata JR, Connolly DT, Waters MG, Richman JG.

J Med Chem. 2012 Apr 26;55(8):3644-66. doi: 10.1021/jm2010964. Epub 2012 Apr 9.


Oxford unicompartmental knee arthroplasty: medial pain and functional outcome in the medium term.

Edmondson MC, Isaac D, Wijeratna M, Brink S, Gibb P, Skinner P.

J Orthop Surg Res. 2011 Oct 10;6:52. doi: 10.1186/1749-799X-6-52.


GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo.

Vojnov L, Martins MA, Almeida JR, Ende Z, Rakasz EG, Reynolds MR, Leon EJ, Weisgrau KL, Burwitz BJ, Folkvord JM, de Santana MG, Neves PC, Connick E, Skinner PJ, Gostick E, O'Connor DH, Wilson NA, Bonaldo MC, Galler R, Price DA, Douek DC, Watkins DI.

PLoS One. 2011;6(8):e23515. doi: 10.1371/journal.pone.0023515. Epub 2011 Aug 26.


Transperitoneal removal of an intrapelvic acetabular component after total hip replacement and salvage of a destroyed acetabulum.

Sarasin SM, Karthikeyan R, Skinner P, Nassef A, Stockley I.

J Bone Joint Surg Br. 2011 Jun;93(6):844-6. doi: 10.1302/0301-620X.93B6.26323.


Selection and characterization of DNA aptamers against PrP(Sc).

Wang P, Hatcher KL, Bartz JC, Chen SG, Skinner P, Richt J, Liu H, Sreevatsan S.

Exp Biol Med (Maywood). 2011 Apr 1;236(4):466-76. doi: 10.1258/ebm.2011.010323. Epub 2011 Mar 28.


Ischiorectal fossa phosphaturic mesenchymal tumour excised using intra-operative endoanal ultrasonography.

Tiernan JP, Klucinski A, Peel NF, Skinner PP.

Colorectal Dis. 2011 Aug;13(8):e250-1. doi: 10.1111/j.1463-1318.2010.02430.x. No abstract available.


Excellent outcomes after emergency groin hernia repair.

Tiernan JP, Katsarelis H, Garner JP, Skinner PP.

Hernia. 2010 Oct;14(5):485-8. doi: 10.1007/s10029-010-0667-y. Epub 2010 May 5.


Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a).

Boatman PD, Schrader TO, Kasem M, Johnson BR, Skinner PJ, Jung JK, Xu J, Cherrier MC, Webb PJ, Semple G, Sage CR, Knudsen J, Chen R, Taggart AK, Carballo-Jane E, Richman JG.

Bioorg Med Chem Lett. 2010 May 1;20(9):2797-800. doi: 10.1016/j.bmcl.2010.03.062. Epub 2010 Mar 20.


UK coloproctologists' current opinions on anastomotic technique and configuration.

Shariff U, Narula H, Skinner P.

Colorectal Dis. 2010 Jul;12(7):708-9. doi: 10.1111/j.1463-1318.2010.02226.x. Epub 2010 Jan 27. No abstract available.


A technique to simultaneously visualize virus-specific CD8+ T cells and virus-infected cells in situ.

Li Q, Skinner PJ, Duan L, Haase AT.

J Vis Exp. 2009 Aug 13;(30). pii: 1561. doi: 10.3791/1561.


5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109b.

Skinner PJ, Webb PJ, Sage CR, Dang TH, Pride CC, Chen R, Tamura SY, Richman JG, Connolly DT, Semple G.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4207-9. doi: 10.1016/j.bmcl.2009.05.108. Epub 2009 May 30.


Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection.

Li Q, Skinner PJ, Ha SJ, Duan L, Mattila TL, Hage A, White C, Barber DL, O'Mara L, Southern PJ, Reilly CS, Carlis JV, Miller CJ, Ahmed R, Haase AT.

Science. 2009 Mar 27;323(5922):1726-9. doi: 10.1126/science.1168676.


Localized populations of CD8 MHC class I tetramer SIV-specific T cells in lymphoid follicles and genital epithelium.

Hong JJ, Reynolds MR, Mattila TL, Hage A, Watkins DI, Miller CJ, Skinner PJ.

PLoS One. 2009;4(1):e4131. doi: 10.1371/journal.pone.0004131. Epub 2009 Jan 5.


Protective attenuated lentivirus immunization induces SIV-specific T cells in the genital tract of rhesus monkeys.

Genescà M, Skinner PJ, Bost KM, Lu D, Wang Y, Rourke TL, Haase AT, McChesney MB, Miller CJ.

Mucosal Immunol. 2008 May;1(3):219-28. doi: 10.1038/mi.2008.6. Epub 2008 Mar 5.


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