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Items: 1 to 50 of 91

1.

In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images.

Christiansen EM, Yang SJ, Ando DM, Javaherian A, Skibinski G, Lipnick S, Mount E, O'Neil A, Shah K, Lee AK, Goyal P, Fedus W, Poplin R, Esteva A, Berndl M, Rubin LL, Nelson P, Finkbeiner S.

Cell. 2018 Apr 19;173(3):792-803.e19. doi: 10.1016/j.cell.2018.03.040. Epub 2018 Apr 12.

2.

iPS cells in the study of PD molecular pathogenesis.

Cobb MM, Ravisankar A, Skibinski G, Finkbeiner S.

Cell Tissue Res. 2018 Jul;373(1):61-77. doi: 10.1007/s00441-017-2749-y. Epub 2017 Dec 12. Review.

3.

Nrf2 mitigates LRRK2- and α-synuclein-induced neurodegeneration by modulating proteostasis.

Skibinski G, Hwang V, Ando DM, Daub A, Lee AK, Ravisankar A, Modan S, Finucane MM, Shaby BA, Finkbeiner S.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1165-1170. doi: 10.1073/pnas.1522872114. Epub 2016 Dec 27.

4.

A three-groups model for high-throughput survival screens.

Shaby BA, Skibinski G, Ando M, LaDow ES, Finkbeiner S.

Biometrics. 2016 Sep;72(3):936-44. doi: 10.1111/biom.12479. Epub 2016 Jan 28.

5.

Epidermal Growth Factor Removal or Tyrphostin AG1478 Treatment Reduces Goblet Cells & Mucus Secretion of Epithelial Cells from Asthmatic Children Using the Air-Liquid Interface Model.

Parker JC, Douglas I, Bell J, Comer D, Bailie K, Skibinski G, Heaney LG, Shields MD.

PLoS One. 2015 Jun 9;10(6):e0129546. doi: 10.1371/journal.pone.0129546. eCollection 2015.

6.

Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease.

Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, Callaway K, Anderson JP, Jobling MF, Buell AK, Yednock TA, Knowles TP, Vendruscolo M, Christodoulou J, Dobson CM, Schenk D, McConlogue L.

PLoS One. 2014 Feb 14;9(2):e87133. doi: 10.1371/journal.pone.0087133. eCollection 2014. Erratum in: PLoS One. 2014;9(5):e99274.

7.

Nasal epithelial cells can act as a physiological surrogate for paediatric asthma studies.

Thavagnanam S, Parker JC, McBrien ME, Skibinski G, Shields MD, Heaney LG.

PLoS One. 2014 Jan 27;9(1):e85802. doi: 10.1371/journal.pone.0085802. eCollection 2014.

8.

Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies.

Skibinski G, Nakamura K, Cookson MR, Finkbeiner S.

J Neurosci. 2014 Jan 8;34(2):418-33. doi: 10.1523/JNEUROSCI.2712-13.2014.

9.

Chronic IL9 and IL-13 exposure leads to an altered differentiation of ciliated cells in a well-differentiated paediatric bronchial epithelial cell model.

Parker JC, Thavagnanam S, Skibinski G, Lyons J, Bell J, Heaney LG, Shields MD.

PLoS One. 2013 May 9;8(5):e61023. doi: 10.1371/journal.pone.0061023. Print 2013.

10.

The link between antibodies to OxLDL and natural protection against pneumococci depends on D(H) gene conservation.

Vale AM, Kapoor P, Skibinski GA, Elgavish A, Mahmoud TI, Zemlin C, Zemlin M, Burrows PD, Nobrega A, Kearney JF, Briles DE, Schroeder HW Jr.

J Exp Med. 2013 May 6;210(5):875-90.

11.

Longitudinal measures of proteostasis in live neurons: features that determine fate in models of neurodegenerative disease.

Skibinski G, Finkbeiner S.

FEBS Lett. 2013 Apr 17;587(8):1139-46. doi: 10.1016/j.febslet.2013.02.043. Epub 2013 Mar 1. Review.

12.
13.

In vitro modeling of respiratory syncytial virus infection of pediatric bronchial epithelium, the primary target of infection in vivo.

Villenave R, Thavagnanam S, Sarlang S, Parker J, Douglas I, Skibinski G, Heaney LG, McKaigue JP, Coyle PV, Shields MD, Power UF.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5040-5. doi: 10.1073/pnas.1110203109. Epub 2012 Mar 12.

14.

IL-31 does not induce normal human ciliated epithelial cells to differentiate into a phenotype consistent with the pathophysiology of asthma.

Parker JC, Thavagnanam S, Skibinski G, McBrien M, Heaney LG, Shields MD.

Results Immunol. 2012 May 15;2:104-11. doi: 10.1016/j.rinim.2012.05.001. eCollection 2012.

15.

Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma.

Butler CA, McQuaid S, Taggart CC, Weldon S, Carter R, Skibinski G, Warke TJ, Choy DF, McGarvey LP, Bradding P, Arron JR, Heaney LG.

Thorax. 2012 May;67(5):392-8. doi: 10.1136/thoraxjnl-2011-200760. Epub 2011 Dec 8.

PMID:
22156779
16.

Drug discovery in Parkinson's disease-Update and developments in the use of cellular models.

Skibinski G, Finkbeiner S.

Int J High Throughput Screen. 2011 Jun;2011(2):15-25.

17.

Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein.

Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH.

J Biol Chem. 2011 Jun 10;286(23):20710-26. doi: 10.1074/jbc.M110.213538. Epub 2011 Apr 13.

18.

Differential cytopathogenesis of respiratory syncytial virus prototypic and clinical isolates in primary pediatric bronchial epithelial cells.

Villenave R, O'Donoghue D, Thavagnanam S, Touzelet O, Skibinski G, Heaney LG, McKaigue JP, Coyle PV, Shields MD, Power UF.

Virol J. 2011 Jan 27;8:43. doi: 10.1186/1743-422X-8-43.

19.

Inhibition of Experimental Autoimmune Encephalomyelitis in Human C-Reactive Protein Transgenic Mice Is FcγRIIB Dependent.

Hu XZ, Wright TT, Jones NR, Ramos TN, Skibinski GA, McCrory MA, Barnum SR, Szalai AJ.

Autoimmune Dis. 2010 Oct 12;2011:484936. doi: 10.4061/2011/484936.

20.

Effects of IL-13 on mucociliary differentiation of pediatric asthmatic bronchial epithelial cells.

Thavagnanam S, Parker JC, McBrien ME, Skibinski G, Heaney LG, Shields MD.

Pediatr Res. 2011 Feb;69(2):95-100. doi: 10.1203/PDR.0b013e318204edb5.

PMID:
21076368
21.

Cytopathogenesis of Sendai virus in well-differentiated primary pediatric bronchial epithelial cells.

Villenave R, Touzelet O, Thavagnanam S, Sarlang S, Parker J, Skibinski G, Heaney LG, McKaigue JP, Coyle PV, Shields MD, Power UF.

J Virol. 2010 Nov;84(22):11718-28. doi: 10.1128/JVI.00798-10. Epub 2010 Sep 1.

22.

Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis.

Barmada SJ, Skibinski G, Korb E, Rao EJ, Wu JY, Finkbeiner S.

J Neurosci. 2010 Jan 13;30(2):639-49. doi: 10.1523/JNEUROSCI.4988-09.2010.

23.

Wild-type measles virus infection of primary epithelial cells occurs via the basolateral surface without syncytium formation or release of infectious virus.

Ludlow M, Rennick LJ, Sarlang S, Skibinski G, McQuaid S, Moore T, de Swart RL, Duprex WP.

J Gen Virol. 2010 Apr;91(Pt 4):971-9. doi: 10.1099/vir.0.016428-0. Epub 2009 Nov 18.

PMID:
19923259
24.

A 3-D well-differentiated model of pediatric bronchial epithelium demonstrates unstimulated morphological differences between asthmatic and nonasthmatic cells.

Parker J, Sarlang S, Thavagnanam S, Williamson G, O'donoghue D, Villenave R, Power U, Shields M, Heaney L, Skibinski G.

Pediatr Res. 2010 Jan;67(1):17-22. doi: 10.1203/PDR.0b013e3181c0b200. Erratum in: Pediatr Res. 2014 Nov;76(5):498.

PMID:
19755931
25.

Exaggerated neointima formation in human C-reactive protein transgenic mice is IgG Fc receptor type I (Fc gamma RI)-dependent.

Xing D, Hage FG, Chen YF, McCrory MA, Feng W, Skibinski GA, Majid-Hassan E, Oparil S, Szalai AJ.

Am J Pathol. 2008 Jan;172(1):22-30. Epub 2007 Dec 6.

26.

Bronchial epithelial cell growth regulation in fibroblast cocultures: the role of hepatocyte growth factor.

Skibinski G, Elborn JS, Ennis M.

Am J Physiol Lung Cell Mol Physiol. 2007 Jul;293(1):L69-76. Epub 2007 Mar 23.

27.

Staphylococcus aureus enterotoxins induce IL-8 secretion by human nasal epithelial cells.

O'Brien GJ, Riddell G, Elborn JS, Ennis M, Skibinski G.

Respir Res. 2006 Sep 4;7:115.

28.

ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B).

Parkinson N, Ince PG, Smith MO, Highley R, Skibinski G, Andersen PM, Morrison KE, Pall HS, Hardiman O, Collinge J, Shaw PJ, Fisher EM; MRC Proteomics in ALS Study; FReJA Consortium.

Neurology. 2006 Sep 26;67(6):1074-7. Epub 2006 Jun 28.

PMID:
16807408
29.

Induction of leptin resistance through direct interaction of C-reactive protein with leptin.

Chen K, Li F, Li J, Cai H, Strom S, Bisello A, Kelley DE, Friedman-Einat M, Skibinski GA, McCrory MA, Szalai AJ, Zhao AZ.

Nat Med. 2006 Apr;12(4):425-32. Epub 2006 Apr 2.

PMID:
16582918
30.

Estrogen treatment abrogates neointima formation in human C-reactive protein transgenic mice.

Wang D, Oparil S, Chen YF, McCrory MA, Skibinski GA, Feng W, Szalai AJ.

Arterioscler Thromb Vasc Biol. 2005 Oct;25(10):2094-9. Epub 2005 Jul 28.

PMID:
16051879
31.

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia.

Skibinski G, Parkinson NJ, Brown JM, Chakrabarti L, Lloyd SL, Hummerich H, Nielsen JE, Hodges JR, Spillantini MG, Thusgaard T, Brandner S, Brun A, Rossor MN, Gade A, Johannsen P, Sørensen SA, Gydesen S, Fisher EM, Collinge J.

Nat Genet. 2005 Aug;37(8):806-8. Epub 2005 Jul 24.

PMID:
16041373
32.

Frontotemporal dementia linked to chromosome 3.

Brown J, Gydesen S, Johannsen P, Gade A, Skibinski G, Chakrabarti L, Brun A, Spillantini M, Yancopoulou D, Thusgaard T, Sorensen A, Fisher E, Collinge J; FReJA (Frontotemporal Dementia Research in Jutland Association).

Dement Geriatr Cogn Disord. 2004;17(4):274-6.

PMID:
15178935
33.

The role of hepatocyte growth factor/c-met interactions in the immune system.

Skibinski G.

Arch Immunol Ther Exp (Warsz). 2003;51(5):277-82. Review.

PMID:
14626426
34.

Non-bronchoscopic sampling and culture of bronchial epithelial cells in children.

Doherty GM, Christie SN, Skibinski G, Puddicombe SM, Warke TJ, de Courcey F, Cross AL, Lyons JD, Ennis M, Shields MD, Heaney LG.

Clin Exp Allergy. 2003 Sep;33(9):1221-5.

PMID:
12956742
35.
38.

Disruption of auxin transport is associated with aberrant leaf development in maize

Tsiantis M, Brown MI, Skibinski G, Langdale JA.

Plant Physiol. 1999 Dec;121(4):1163-8.

40.

Enhancement of terminal B lymphocyte differentiation in vitro by fibroblast-like stromal cells from human spleen.

Skibinski G, Skibinska A, Stewart GD, James K.

Eur J Immunol. 1998 Dec;28(12):3940-8.

41.
42.

An exploratory study of sex differences in orientation to clinical practice.

Pardeck JT, Skibinski GJ.

Psychol Rep. 1997 Dec;81(3 Pt 2):1392-4.

PMID:
9461775
43.
44.

Tonsil stromal cell lines expressing follicular dendritic cell-like properties--isolation, characterization and interaction with B lymphocytes.

Skibinski G, Skibinska A, James K.

Biochem Soc Trans. 1997 May;25(2):233S. No abstract available.

PMID:
9191277
45.

IL-6, DHEA and the ageing process.

James K, Premchand N, Skibinska A, Skibinski G, Nicol M, Mason JI.

Mech Ageing Dev. 1997 Feb;93(1-3):15-24.

PMID:
9089567
46.

The use of tissue slices in immunological investigations.

Skibiński G, James K.

Arch Immunol Ther Exp (Warsz). 1997;45(5-6):411-7. Review.

PMID:
9437496
49.
50.

Organ culture of human lymphoid tissue. I. Characteristics of the system.

Hoffmann P, Skibinski G, James K.

J Immunol Methods. 1995 Feb 13;179(1):37-49.

PMID:
7868923

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