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Items: 12


Targeted in situ genome-wide profiling with high efficiency for low cell numbers.

Skene PJ, Henikoff JG, Henikoff S.

Nat Protoc. 2018 May;13(5):1006-1019. doi: 10.1038/nprot.2018.015. Epub 2018 Apr 12.


Transcriptional regulatory networks underlying gene expression changes in Huntington's disease.

Ament SA, Pearl JR, Cantle JP, Bragg RM, Skene PJ, Coffey SR, Bergey DE, Wheeler VC, MacDonald ME, Baliga NS, Rosinski J, Hood LE, Carroll JB, Price ND.

Mol Syst Biol. 2018 Mar 26;14(3):e7435. doi: 10.15252/msb.20167435.


An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites.

Skene PJ, Henikoff S.

Elife. 2017 Jan 16;6. pii: e21856. doi: 10.7554/eLife.21856.


A simple method for generating high-resolution maps of genome-wide protein binding.

Skene PJ, Henikoff S.

Elife. 2015 Jun 16;4:e09225. doi: 10.7554/eLife.09225.


Histones push the envelope.

Skene PJ, Henikoff S.

Nat Struct Mol Biol. 2014 Aug;21(8):651-2. doi: 10.1038/nsmb.2864. No abstract available.


The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1.

Skene PJ, Hernandez AE, Groudine M, Henikoff S.

Elife. 2014 Apr 15;3:e02042. doi: 10.7554/eLife.02042.


CpG island chromatin is shaped by recruitment of ZF-CxxC proteins.

Blackledge NP, Thomson JP, Skene PJ.

Cold Spring Harb Perspect Biol. 2013 Nov 1;5(11):a018648. doi: 10.1101/cshperspect.a018648. Review.


Histone variants in pluripotency and disease.

Skene PJ, Henikoff S.

Development. 2013 Jun;140(12):2513-24. doi: 10.1242/dev.091439. Review.


Chromatin roadblocks to reprogramming 50 years on.

Skene PJ, Henikoff S.

BMC Biol. 2012 Oct 29;10:83. doi: 10.1186/1741-7007-10-83.


Mechanism of initiation site selection promoted by the human rhinovirus 2 internal ribosome entry site.

Kaminski A, Pöyry TA, Skene PJ, Jackson RJ.

J Virol. 2010 Jul;84(13):6578-89. doi: 10.1128/JVI.00123-10. Epub 2010 Apr 28.


CpG islands influence chromatin structure via the CpG-binding protein Cfp1.

Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr AR, Deaton A, Andrews R, James KD, Turner DJ, Illingworth R, Bird A.

Nature. 2010 Apr 15;464(7291):1082-6. doi: 10.1038/nature08924.


Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.

Skene PJ, Illingworth RS, Webb S, Kerr AR, James KD, Turner DJ, Andrews R, Bird AP.

Mol Cell. 2010 Feb 26;37(4):457-68. doi: 10.1016/j.molcel.2010.01.030.

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