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Items: 1 to 50 of 229

1.

Influenza hemagglutinin membrane anchor.

Benton DJ, Nans A, Calder LJ, Turner J, Neu U, Lin YP, Ketelaars E, Kallewaard NL, Corti D, Lanzavecchia A, Gamblin SJ, Rosenthal PB, Skehel JJ.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10112-10117. doi: 10.1073/pnas.1810927115. Epub 2018 Sep 17.

2.

Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.

Kallewaard NL, Corti D, Collins PJ, Neu U, McAuliffe JM, Benjamin E, Wachter-Rosati L, Palmer-Hill FJ, Yuan AQ, Walker PA, Vorlaender MK, Bianchi S, Guarino B, De Marco A, Vanzetta F, Agatic G, Foglierini M, Pinna D, Fernandez-Rodriguez B, Fruehwirth A, Silacci C, Ogrodowicz RW, Martin SR, Sallusto F, Suzich JA, Lanzavecchia A, Zhu Q, Gamblin SJ, Skehel JJ.

Cell. 2016 Jul 28;166(3):596-608. doi: 10.1016/j.cell.2016.05.073. Epub 2016 Jul 21.

3.

Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody.

Xiong X, Corti D, Liu J, Pinna D, Foglierini M, Calder LJ, Martin SR, Lin YP, Walker PA, Collins PJ, Monne I, Suguitan AL Jr, Santos C, Temperton NJ, Subbarao K, Lanzavecchia A, Gamblin SJ, Skehel JJ.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):9430-5. doi: 10.1073/pnas.1510816112. Epub 2015 Jul 13.

4.

Recent evolution of equine influenza and the origin of canine influenza.

Collins PJ, Vachieri SG, Haire LF, Ogrodowicz RW, Martin SR, Walker PA, Xiong X, Gamblin SJ, Skehel JJ.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11175-80. doi: 10.1073/pnas.1406606111. Epub 2014 Jul 14.

5.

Enhanced human receptor binding by H5 haemagglutinins.

Xiong X, Xiao H, Martin SR, Coombs PJ, Liu J, Collins PJ, Vachieri SG, Walker PA, Lin YP, McCauley JW, Gamblin SJ, Skehel JJ.

Virology. 2014 May;456-457:179-87. doi: 10.1016/j.virol.2014.03.008. Epub 2014 Apr 12.

6.

Receptor binding by H10 influenza viruses.

Vachieri SG, Xiong X, Collins PJ, Walker PA, Martin SR, Haire LF, Zhang Y, McCauley JW, Gamblin SJ, Skehel JJ.

Nature. 2014 Jul 24;511(7510):475-7. doi: 10.1038/nature13443.

PMID:
24870229
7.

A novel I221L substitution in neuraminidase confers high-level resistance to oseltamivir in influenza B viruses.

Escuret V, Collins PJ, Casalegno JS, Vachieri SG, Cattle N, Ferraris O, Sabatier M, Frobert E, Caro V, Skehel JJ, Gamblin S, Valla F, Valette M, Ottmann M, McCauley JW, Daniels RS, Lina B.

J Infect Dis. 2014 Oct 15;210(8):1260-9. doi: 10.1093/infdis/jiu244. Epub 2014 May 3.

8.

Recovery of an antiviral antibody response following attrition caused by unrelated infection.

Ng DH, Skehel JJ, Kassiotis G, Langhorne J.

PLoS Pathog. 2014 Jan;10(1):e1003843. doi: 10.1371/journal.ppat.1003843. Epub 2014 Jan 2.

9.

Changes in the hemagglutinin of H5N1 viruses during human infection--influence on receptor binding.

Crusat M, Liu J, Palma AS, Childs RA, Liu Y, Wharton SA, Lin YP, Coombs PJ, Martin SR, Matrosovich M, Chen Z, Stevens DJ, Hien VM, Thanh TT, Nhu le NT, Nguyet LA, Ha do Q, van Doorn HR, Hien TT, Conradt HS, Kiso M, Gamblin SJ, Chai W, Skehel JJ, Hay AJ, Farrar J, de Jong MD, Feizi T.

Virology. 2013 Dec;447(1-2):326-37. doi: 10.1016/j.virol.2013.08.010. Epub 2013 Sep 17.

10.

Recognition of sulphated and fucosylated receptor sialosides by A/Vietnam/1194/2004 (H5N1) influenza virus.

Xiong X, Tuzikov A, Coombs PJ, Martin SR, Walker PA, Gamblin SJ, Bovin N, Skehel JJ.

Virus Res. 2013 Dec 5;178(1):12-4. doi: 10.1016/j.virusres.2013.08.007. Epub 2013 Sep 10. No abstract available.

PMID:
24036174
11.

Receptor binding by an H7N9 influenza virus from humans.

Xiong X, Martin SR, Haire LF, Wharton SA, Daniels RS, Bennett MS, McCauley JW, Collins PJ, Walker PA, Skehel JJ, Gamblin SJ.

Nature. 2013 Jul 25;499(7459):496-9. doi: 10.1038/nature12372.

PMID:
23787694
12.

Receptor binding by a ferret-transmissible H5 avian influenza virus.

Xiong X, Coombs PJ, Martin SR, Liu J, Xiao H, McCauley JW, Locher K, Walker PA, Collins PJ, Kawaoka Y, Skehel JJ, Gamblin SJ.

Nature. 2013 May 16;497(7449):392-6. doi: 10.1038/nature12144. Epub 2013 Apr 24.

PMID:
23615615
13.

Evolution of the receptor binding properties of the influenza A(H3N2) hemagglutinin.

Lin YP, Xiong X, Wharton SA, Martin SR, Coombs PJ, Vachieri SG, Christodoulou E, Walker PA, Liu J, Skehel JJ, Gamblin SJ, Hay AJ, Daniels RS, McCauley JW.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21474-9. doi: 10.1073/pnas.1218841110. Epub 2012 Dec 10. Erratum in: Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2677.

14.

H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis.

van der Vries E, Collins PJ, Vachieri SG, Xiong X, Liu J, Walker PA, Haire LF, Hay AJ, Schutten M, Osterhaus AD, Martin SR, Boucher CA, Skehel JJ, Gamblin SJ.

PLoS Pathog. 2012 Sep;8(9):e1002914. doi: 10.1371/journal.ppat.1002914. Epub 2012 Sep 20.

15.

A human antibody recognizing a conserved epitope of H5 hemagglutinin broadly neutralizes highly pathogenic avian influenza H5N1 viruses.

Hu H, Voss J, Zhang G, Buchy P, Zuo T, Wang L, Wang F, Zhou F, Wang G, Tsai C, Calder L, Gamblin SJ, Zhang L, Deubel V, Zhou B, Skehel JJ, Zhou P.

J Virol. 2012 Mar;86(6):2978-89. doi: 10.1128/JVI.06665-11. Epub 2012 Jan 11.

16.

A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins.

Corti D, Voss J, Gamblin SJ, Codoni G, Macagno A, Jarrossay D, Vachieri SG, Pinna D, Minola A, Vanzetta F, Silacci C, Fernandez-Rodriguez BM, Agatic G, Bianchi S, Giacchetto-Sasselli I, Calder L, Sallusto F, Collins P, Haire LF, Temperton N, Langedijk JP, Skehel JJ, Lanzavecchia A.

Science. 2011 Aug 12;333(6044):850-6. doi: 10.1126/science.1205669. Epub 2011 Jul 28.

17.

Influenza hemagglutinin and neuraminidase membrane glycoproteins.

Gamblin SJ, Skehel JJ.

J Biol Chem. 2010 Sep 10;285(37):28403-9. doi: 10.1074/jbc.R110.129809. Epub 2010 Jun 10. Review.

18.

Structural basis for oseltamivir resistance of influenza viruses.

Collins PJ, Haire LF, Lin YP, Liu J, Russell RJ, Walker PA, Martin SR, Daniels RS, Gregory V, Skehel JJ, Gamblin SJ, Hay AJ.

Vaccine. 2009 Oct 23;27(45):6317-23. doi: 10.1016/j.vaccine.2009.07.017.

PMID:
19840667
19.

Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957.

Liu J, Stevens DJ, Haire LF, Walker PA, Coombs PJ, Russell RJ, Gamblin SJ, Skehel JJ.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17175-80. doi: 10.1073/pnas.0906849106. Epub 2009 Sep 28.

20.

Composition and functions of the influenza fusion peptide.

Cross KJ, Langley WA, Russell RJ, Skehel JJ, Steinhauer DA.

Protein Pept Lett. 2009;16(7):766-78. Review.

PMID:
19601906
21.

Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion.

Russell RJ, Kerry PS, Stevens DJ, Steinhauer DA, Martin SR, Gamblin SJ, Skehel JJ.

Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17736-41. doi: 10.1073/pnas.0807142105. Epub 2008 Nov 12.

22.

Single-particle kinetics of influenza virus membrane fusion.

Floyd DL, Ragains JR, Skehel JJ, Harrison SC, van Oijen AM.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15382-7. doi: 10.1073/pnas.0807771105. Epub 2008 Sep 30.

23.

Fred Brown: 31 January 1925 - 20 February 2004.

Rowlands DJ, Skehel JJ.

Biogr Mem Fellows R Soc. 2007;53:93-108.

PMID:
18543464
24.

Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.

Collins PJ, Haire LF, Lin YP, Liu J, Russell RJ, Walker PA, Skehel JJ, Martin SR, Hay AJ, Gamblin SJ.

Nature. 2008 Jun 26;453(7199):1258-61. doi: 10.1038/nature06956. Epub 2008 May 14.

PMID:
18480754
25.

Infectivity studies of influenza virus hemagglutinin receptor binding site mutants in mice.

Meisner J, Szretter KJ, Bradley KC, Langley WA, Li ZN, Lee BJ, Thoennes S, Martin J, Skehel JJ, Russell RJ, Katz JM, Steinhauer DA.

J Virol. 2008 May;82(10):5079-83. doi: 10.1128/JVI.01958-07. Epub 2008 Mar 19.

26.

Analysis of residues near the fusion peptide in the influenza hemagglutinin structure for roles in triggering membrane fusion.

Thoennes S, Li ZN, Lee BJ, Langley WA, Skehel JJ, Russell RJ, Steinhauer DA.

Virology. 2008 Jan 20;370(2):403-14. Epub 2007 Oct 23.

27.

High level expression of soluble glycoproteins in the allantoic fluid of embryonated chicken eggs using a Sendai virus minigenome system.

Corral T, Ver LS, Mottet G, Cano O, García-Barreno B, Calder LJ, Skehel JJ, Roux L, Melero JA.

BMC Biotechnol. 2007 Apr 5;7:17.

28.

Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors.

Yamada S, Suzuki Y, Suzuki T, Le MQ, Nidom CA, Sakai-Tagawa Y, Muramoto Y, Ito M, Kiso M, Horimoto T, Shinya K, Sawada T, Kiso M, Usui T, Murata T, Lin Y, Hay A, Haire LF, Stevens DJ, Russell RJ, Gamblin SJ, Skehel JJ, Kawaoka Y.

Nature. 2006 Nov 16;444(7117):378-82.

PMID:
17108965
29.

Variation and infectivity neutralization in influenza.

Knossow M, Skehel JJ.

Immunology. 2006 Sep;119(1):1-7. Review.

30.

The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.

Russell RJ, Haire LF, Stevens DJ, Collins PJ, Lin YP, Blackburn GM, Hay AJ, Gamblin SJ, Skehel JJ.

Nature. 2006 Sep 7;443(7107):45-9. Epub 2006 Aug 16.

PMID:
16915235
31.

Sequence elements of the fusion peptide of human respiratory syncytial virus fusion protein required for activity.

Martín D, Calder LJ, García-Barreno B, Skehel JJ, Melero JA.

J Gen Virol. 2006 Jun;87(Pt 6):1649-58.

PMID:
16690930
32.

Avian and human receptor binding by hemagglutinins of influenza A viruses.

Russell RJ, Stevens DJ, Haire LF, Gamblin SJ, Skehel JJ.

Glycoconj J. 2006 Feb;23(1-2):85-92.

PMID:
16575525
33.

Structure of an unliganded simian immunodeficiency virus gp120 core.

Chen B, Vogan EM, Gong H, Skehel JJ, Wiley DC, Harrison SC.

Nature. 2005 Feb 24;433(7028):834-41.

PMID:
15729334
34.

Determining the structure of an unliganded and fully glycosylated SIV gp120 envelope glycoprotein.

Chen B, Vogan EM, Gong H, Skehel JJ, Wiley DC, Harrison SC.

Structure. 2005 Feb;13(2):197-211. Erratum in: Structure (Camb). 2005 Mar;13(3):493.

35.

Influenza a viruses with mutations in the m1 helix six domain display a wide variety of morphological phenotypes.

Burleigh LM, Calder LJ, Skehel JJ, Steinhauer DA.

J Virol. 2005 Jan;79(2):1262-70.

36.

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins.

Blixt O, Head S, Mondala T, Scanlan C, Huflejt ME, Alvarez R, Bryan MC, Fazio F, Calarese D, Stevens J, Razi N, Stevens DJ, Skehel JJ, van Die I, Burton DR, Wilson IA, Cummings R, Bovin N, Wong CH, Paulson JC.

Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17033-8. Epub 2004 Nov 24.

37.

Thermostability of the human respiratory syncytial virus fusion protein before and after activation: implications for the membrane-fusion mechanism.

Ruiz-Argüello MB, Martín D, Wharton SA, Calder LJ, Martín SR, Cano O, Calero M, García-Barreno B, Skehel JJ, Melero JA.

J Gen Virol. 2004 Dec;85(Pt 12):3677-87.

PMID:
15557241
38.

Plasticity of influenza haemagglutinin fusion peptides and their interaction with lipid bilayers.

Vaccaro L, Cross KJ, Kleinjung J, Straus SK, Thomas DJ, Wharton SA, Skehel JJ, Fraternali F.

Biophys J. 2005 Jan;88(1):25-36. Epub 2004 Oct 8.

39.

H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes.

Russell RJ, Gamblin SJ, Haire LF, Stevens DJ, Xiao B, Ha Y, Skehel JJ.

Virology. 2004 Aug 1;325(2):287-96.

40.

Full-length influenza hemagglutinin HA2 refolds into the trimeric low-pH-induced conformation.

Swalley SE, Baker BM, Calder LJ, Harrison SC, Skehel JJ, Wiley DC.

Biochemistry. 2004 May 18;43(19):5902-11.

PMID:
15134464
41.

A chimeric protein of simian immunodeficiency virus envelope glycoprotein gp140 and Escherichia coli aspartate transcarbamoylase.

Chen B, Cheng Y, Calder L, Harrison SC, Reinherz EL, Skehel JJ, Wiley DC.

J Virol. 2004 May;78(9):4508-16.

42.

The structure and receptor binding properties of the 1918 influenza hemagglutinin.

Gamblin SJ, Haire LF, Russell RJ, Stevens DJ, Xiao B, Ha Y, Vasisht N, Steinhauer DA, Daniels RS, Elliot A, Wiley DC, Skehel JJ.

Science. 2004 Mar 19;303(5665):1838-42. Epub 2004 Feb 5.

43.
44.

Mechanism of neutralization of influenza virus infectivity by antibodies.

Knossow M, Gaudier M, Douglas A, Barrère B, Bizebard T, Barbey C, Gigant B, Skehel JJ.

Virology. 2002 Oct 25;302(2):294-8.

45.

Genetics of influenza viruses.

Steinhauer DA, Skehel JJ.

Annu Rev Genet. 2002;36:305-32. Epub 2002 Jun 11. Review.

PMID:
12429695
46.

Effect of proteolytic processing at two distinct sites on shape and aggregation of an anchorless fusion protein of human respiratory syncytial virus and fate of the intervening segment.

Begoña Ruiz-Argüello M, González-Reyes L, Calder LJ, Palomo C, Martín D, Saíz MJ, García-Barreno B, Skehel JJ, Melero JA.

Virology. 2002 Jul 5;298(2):317-26.

47.

Influenza haemagglutinin.

Skehel JJ, Wiley DC.

Vaccine. 2002 May 15;20 Suppl 2:S51-4.

PMID:
12110258
48.

An antibody that prevents the hemagglutinin low pH fusogenic transition.

Barbey-Martin C, Gigant B, Bizebard T, Calder LJ, Wharton SA, Skehel JJ, Knossow M.

Virology. 2002 Mar 1;294(1):70-4.

49.
50.

X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs.

Ha Y, Stevens DJ, Skehel JJ, Wiley DC.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11181-6. Epub 2001 Sep 18.

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