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Items: 1 to 50 of 197

1.

Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells.

Pothlichet J, Meunier I, Davis BK, Ting JP, Skamene E, von Messling V, Vidal SM.

PLoS Pathog. 2013;9(4):e1003256. doi: 10.1371/journal.ppat.1003256. Epub 2013 Apr 11.

2.

Genetic control of high density lipoprotein-cholesterol in AcB/BcA recombinant congenic strains of mice.

Wiltshire SA, Diez E, Miao Q, Dubé MP, Gagné M, Paquette O, Lafrenière RG, Ndao M, Castellani LW, Skamene E, Vidal SM, Fortin A.

Physiol Genomics. 2012 Sep 1;44(17):843-52. doi: 10.1152/physiolgenomics.00025.2012. Epub 2012 Jul 17.

3.

Mapping of clinical and expression quantitative trait loci in a sex-dependent effect of host susceptibility to mouse-adapted influenza H3N2/HK/1/68.

Boivin GA, Pothlichet J, Skamene E, Brown EG, Loredo-Osti JC, Sladek R, Vidal SM.

J Immunol. 2012 Apr 15;188(8):3949-60. doi: 10.4049/jimmunol.1103320. Epub 2012 Mar 16.

4.

Positional cloning of a quantitative trait locus contributing to pain sensitivity: possible mediation by Tyrp1.

Fortin A, Diez E, Ritchie J, Sotocinal SG, Dube MP, Gagne M, Paquette O, Skamene E, Mogil JS.

Genes Brain Behav. 2010 Nov;9(8):856-67. doi: 10.1111/j.1601-183X.2010.00618.x.

5.

Identification of novel chromosomal regions associated with airway hyperresponsiveness in recombinant congenic strains of mice.

Camateros P, Marino R, Fortin A, Martin JG, Skamene E, Sladek R, Radzioch D.

Mamm Genome. 2010 Feb;21(1-2):28-38. doi: 10.1007/s00335-009-9236-z. Epub 2009 Dec 15.

PMID:
20012967
6.

Genetic determinants of emotionality and stress response in AcB/BcA recombinant congenic mice and in silico evidence of convergence with cardiovascular candidate genes.

Thifault S, Ondrej S, Sun Y, Fortin A, Skamene E, Lalonde R, Tremblay J, Hamet P.

Hum Mol Genet. 2008 Feb 1;17(3):331-44. Epub 2007 Oct 3.

PMID:
17913702
7.

The AcB/BcA recombinant congenic strains of mice: strategies for phenotype dissection, mapping and cloning of quantitative trait genes.

Fortin A, Diez E, Henderson JE, Mogil JS, Gros P, Skamene E.

Novartis Found Symp. 2007;281:141-53; discussion 153-5, 208-9. Review.

PMID:
17534071
8.

Agonistic antibodies to Fas induce a breach in the endothelial lining of the liver and a breakdown in B cell tolerance.

Newkirk MM, Nowak U, Skamene E, Iera D, Desbarats J.

Clin Exp Immunol. 2007 Feb;147(2):346-51.

9.

Rheumatoid factor induction in murine models of liver injury.

Nowak U, Gill K, Skamene E, Newkirk MM.

Clin Exp Immunol. 2007 Feb;147(2):324-9.

10.

Toll-like receptors, cytokines and the immunotherapeutics of asthma.

Camateros P, Moisan J, Hénault J, De Sanctis J, Skamene E, Radzioch D.

Curr Pharm Des. 2006;12(19):2365-74. Review.

PMID:
16842184
11.

Identification of informative strains and provisional QTL mapping of amphetamine (AMPH)-induced locomotion in recombinant congenic strains (RCS) of mice.

Torkamanzehi A, Boksa P, Ayoubi M, Fortier ME, Ng Ying Kin NM, Skamene E, Rouleau G, Joober R.

Behav Genet. 2006 Nov;36(6):903-13. Epub 2006 May 19.

PMID:
16710777
12.

Mapping cis-acting regulatory variation in recombinant congenic strains.

Lee PD, Ge B, Greenwood CM, Sinnett D, Fortin Y, Brunet S, Fortin A, Takane M, Skamene E, Pastinen T, Hallett M, Hudson TJ, Sladek R.

Physiol Genomics. 2006 Apr 13;25(2):294-302. Epub 2006 Jan 31.

PMID:
16449383
13.

Linkage of leprosy susceptibility to Parkinson's disease genes.

Buschman E, Skamene E.

Int J Lepr Other Mycobact Dis. 2004 Jun;72(2):169-70.

PMID:
15301585
14.

Leprosy susceptibility revealed.

Buschman E, Skamene E.

Int J Lepr Other Mycobact Dis. 2003 Jun;71(2):115-8.

PMID:
12914135
15.

Anti-tumour necrosis factor agents and tuberculosis risk: mechanisms of action and clinical management.

Gardam MA, Keystone EC, Menzies R, Manners S, Skamene E, Long R, Vinh DC.

Lancet Infect Dis. 2003 Mar;3(3):148-55. Review.

PMID:
12614731
16.

Recombinant congenic strains of mice: a new tool for the genetic dissection of efficacy and toxicity of adjuvants.

Di Marco S, Moisan J, Boghdady ML, Skamene E, Radzioch D.

Vaccine. 2003 Feb 14;21(9-10):832-5.

PMID:
12547590
17.

Provisional mapping of quantitative trait loci modulating the acoustic startle response and prepulse inhibition of acoustic startle.

Joober R, Zarate JM, Rouleau GA, Skamene E, Boksa P.

Neuropsychopharmacology. 2002 Nov;27(5):765-81.

18.

Forward genetics of infectious diseases: immunological impact.

Casanova JL, Schurr E, Abel L, Skamene E.

Trends Immunol. 2002 Oct;23(10):469-72. No abstract available.

PMID:
12297411
19.
21.

Genetic analysis of influences on survival following Toxoplasma gondii infection.

Johnson J, Suzuki Y, Mack D, Mui E, Estes R, David C, Skamene E, Forman J, McLeod R.

Int J Parasitol. 2002 Feb;32(2):179-85.

PMID:
11812495
22.

Clearance of infection with Mycobacterium bovis BCG in mice is enhanced by treatment with S28463 (R-848), and its efficiency depends on expression of wild-type Nramp1 (resistance allele).

Moisan J, Wojciechowski W, Guilbault C, Lachance C, Di Marco S, Skamene E, Matlashewski G, Radzioch D.

Antimicrob Agents Chemother. 2001 Nov;45(11):3059-64.

23.

Identification of a new malaria susceptibility locus (Char4) in recombinant congenic strains of mice.

Fortin A, Cardon LR, Tam M, Skamene E, Stevenson MM, Gros P.

Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10793-8. Epub 2001 Sep 4. Erratum in: Proc Natl Acad Sci U S A 2001 Dec 4;98(25):14744.

24.

Recombinant congenic strains derived from A/J and C57BL/6J: a tool for genetic dissection of complex traits.

Fortin A, Diez E, Rochefort D, Laroche L, Malo D, Rouleau GA, Gros P, Skamene E.

Genomics. 2001 May 15;74(1):21-35.

PMID:
11374899
25.

From Bcg/Lsh/Ity to Nramp1: three decades of search and research.

Buschman E, Skamene E.

Drug Metab Dispos. 2001 Apr;29(4 Pt 2):471-3. No abstract available.

PMID:
11259334
26.

Cloning and characterization of the murine toll-like receptor 5 (Tlr5) gene: sequence and mRNA expression studies in Salmonella-susceptible MOLF/Ei mice.

Sebastiani G, Leveque G, Larivière L, Laroche L, Skamene E, Gros P, Malo D.

Genomics. 2000 Mar 15;64(3):230-40.

PMID:
10756091
27.

Variants of the human NRAMP1 gene and altered human immunodeficiency virus infection susceptibility.

Marquet S, Sánchez FO, Arias M, Rodríguez J, París SC, Skamene E, Schurr E, García LF.

J Infect Dis. 1999 Nov;180(5):1521-5.

PMID:
10515811
29.

Comparative genomics and host resistance against infectious diseases.

Qureshi ST, Skamene E, Malo D.

Emerg Infect Dis. 1999 Jan-Feb;5(1):36-47. Review.

30.

Genetic control of susceptibility to infections with intracellular pathogens.

Skamene E.

Pathol Biol (Paris). 1998 Nov;46(9):689-92. Review. English, French. No abstract available.

PMID:
9885818
31.
32.

Impaired ability of Cftr knockout mice to control lung infection with Pseudomonas aeruginosa.

Gosselin D, Stevenson MM, Cowley EA, Griesenbach U, Eidelman DH, Boulé M, Tam MF, Kent G, Skamene E, Tsui LC, Radzioch D.

Am J Respir Crit Care Med. 1998 Apr;157(4 Pt 1):1253-62.

PMID:
9563748
33.
34.

Phenotypic difference between Bcg(r) and Bcg(s) macrophages is related to differences in protein-kinase-C-dependent signalling.

Olivier M, Cook P, Desanctis J, Hel Z, Wojciechowski W, Reiner NE, Skamene E, Radzioch D.

Eur J Biochem. 1998 Feb 1;251(3):734-43.

35.

Mapping of genetic modulators of natural resistance to infection with Salmonella typhimurium in wild-derived mice.

Sebastiani G, Olien L, Gauthier S, Skamene E, Morgan K, Gros P, Malo D.

Genomics. 1998 Jan 15;47(2):180-6.

PMID:
9479490
36.

Susceptibility to leprosy is linked to the human NRAMP1 gene.

Abel L, Sánchez FO, Oberti J, Thuc NV, Hoa LV, Lap VD, Skamene E, Lagrange PH, Schurr E.

J Infect Dis. 1998 Jan;177(1):133-45.

PMID:
9419180
37.

Genetic control of blood parasitaemia in mouse malaria maps to chromosome 8.

Fortin A, Belouchi A, Tam MF, Cardon L, Skamene E, Stevenson MM, Gros P.

Nat Genet. 1997 Dec;17(4):382-3. No abstract available.

PMID:
9398835
38.

Genetically regulated response to intravesical bacillus Calmette Guerin immunotherapy of orthotopic murine bladder tumor.

Kadhim SA, Chin JL, Batislam E, Karlik SJ, Garcia B, Skamene E.

J Urol. 1997 Aug;158(2):646-52.

PMID:
9224385
39.

The in vivo antibody response against exogenous antigens is not influenced by the mouse Bcg (Nramp1) gene.

Sírová M, Hovorka O, Ríha I, Ríhová B, Baudys M, Kim SW, Skamene E.

Immunology. 1997 Apr;90(4):626-31.

40.

Nonspecific resistance to Mycobacteria: the role of the Nramp1 gene.

Buschman E, Vidal S, Skamene E.

Behring Inst Mitt. 1997 Mar;(99):51-7. Review.

PMID:
9303202
41.

I-A beta gene expression regulation in macrophages derived from mice susceptible or resistant to infection with M. bovis BCG.

Barrera LF, Kramnik I, Skamene E, Radzioch D.

Mol Immunol. 1997 Mar;34(4):343-55.

PMID:
9244347
42.

High-resolution linkage map of mouse chromosome 13 in the vicinity of the host resistance locus Lgn1.

Beckers MC, Ernst E, Diez E, Morissette C, Gervais F, Hunter K, Housman D, Yoshida S, Skamene E, Gros P.

Genomics. 1997 Feb 1;39(3):254-63.

PMID:
9119362
44.

The Bcg/Ity/Lsh locus: genetic transfer of resistance to infections in C57BL/6J mice transgenic for the Nramp1 Gly169 allele.

Govoni G, Vidal S, Gauthier S, Skamene E, Malo D, Gros P.

Infect Immun. 1996 Aug;64(8):2923-9.

45.

PCR-analyzed microsatellites for the inbred mouse strain 129/Sv, the strain most commonly used in gene knockout technology.

Matouk C, Gosselin D, Malo D, Skamene E, Radzioch D.

Mamm Genome. 1996 Aug;7(8):603-5. No abstract available.

PMID:
8678982
46.

A high-resolution map in the chromosomal region surrounding the Lps locus.

Qureshi ST, Larivière L, Sebastiani G, Clermont S, Skamene E, Gros P, Malo D.

Genomics. 1996 Feb 1;31(3):283-94.

PMID:
8838309
47.
48.

Genetic and physical mapping of the natural resistance-associated macrophage protein 1 (NRAMP1) in chicken.

Hu J, Bumstead N, Burke D, Ponce de León FA, Skamene E, Gros P, Malo D.

Mamm Genome. 1995 Nov;6(11):809-15.

PMID:
8597640
49.
50.

The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene.

Vidal S, Tremblay ML, Govoni G, Gauthier S, Sebastiani G, Malo D, Skamene E, Olivier M, Jothy S, Gros P.

J Exp Med. 1995 Sep 1;182(3):655-66.

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