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Items: 1 to 50 of 61

1.

Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2.

Higgs MR, Sato K, Reynolds JJ, Begum S, Bayley R, Goula A, Vernet A, Paquin KL, Skalnik DG, Kobayashi W, Takata M, Howlett NG, Kurumizaka H, Kimura H, Stewart GS.

Mol Cell. 2018 Jul 5;71(1):25-41.e6. doi: 10.1016/j.molcel.2018.05.018. Epub 2018 Jun 21.

2.

Efficient differentiation of murine embryonic stem cells requires the binding of CXXC finger protein 1 to DNA or methylated histone H3-Lys4.

Mahadevan J, Skalnik DG.

Gene. 2016 Dec 5;594(1):1-9. doi: 10.1016/j.gene.2016.08.048. Epub 2016 Aug 30.

3.

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

Alicea-Velázquez NL, Shinsky SA, Loh DM, Lee JH, Skalnik DG, Cosgrove MS.

J Biol Chem. 2016 Oct 21;291(43):22357-22372. Epub 2016 Aug 25.

4.

H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass.

Fang L, Zhang J, Zhang H, Yang X, Jin X, Zhang L, Skalnik DG, Jin Y, Zhang Y, Huang X, Li J, Wong J.

Stem Cells. 2016 Mar;34(3):565-80. doi: 10.1002/stem.2250. Epub 2016 Jan 19.

5.

The epigenetic regulator CXXC finger protein 1 is essential for murine hematopoiesis.

Chun KT, Li B, Dobrota E, Tate C, Lee JH, Khan S, Haneline L, HogenEsch H, Skalnik DG.

PLoS One. 2014 Dec 3;9(12):e113745. doi: 10.1371/journal.pone.0113745. eCollection 2014.

6.
7.

Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.

Dharmarajan V, Lee JH, Patel A, Skalnik DG, Cosgrove MS.

J Biol Chem. 2012 Aug 10;287(33):27275-89. doi: 10.1074/jbc.M112.364125. Epub 2012 Jun 3.

8.

Dynamic loss of H2B ubiquitylation without corresponding changes in H3K4 trimethylation during myogenic differentiation.

Vethantham V, Yang Y, Bowman C, Asp P, Lee JH, Skalnik DG, Dynlacht BD.

Mol Cell Biol. 2012 Mar;32(6):1044-55. doi: 10.1128/MCB.06026-11. Epub 2012 Jan 17.

9.

The human immunodeficiency virus protease inhibitor ritonavir inhibits lung cancer cells, in part, by inhibition of survivin.

Srirangam A, Milani M, Mitra R, Guo Z, Rodriguez M, Kathuria H, Fukuda S, Rizzardi A, Schmechel S, Skalnik DG, Pelus LM, Potter DA.

J Thorac Oncol. 2011 Apr;6(4):661-70. doi: 10.1097/JTO.0b013e31820c9e3c.

10.

The epigenetic regulator Cfp1.

Skalnik DG.

Biomol Concepts. 2010 Dec 1;1(5-6):325-34. doi: 10.1515/bmc.2010.031.

PMID:
25962006
11.

Identification and characterization of a novel human PP1 phosphatase complex.

Lee JH, You J, Dobrota E, Skalnik DG.

J Biol Chem. 2010 Aug 6;285(32):24466-76. doi: 10.1074/jbc.M110.109801. Epub 2010 Jun 1.

12.

CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin.

Tate CM, Lee JH, Skalnik DG.

FEBS J. 2010 Jan;277(1):210-23. doi: 10.1111/j.1742-4658.2009.07475.x. Epub 2009 Nov 27. Erratum in: FEBS J. 2010 Jun;277(11):2564.

13.

Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity.

Tate CM, Fishel ML, Holleran JL, Egorin MJ, Skalnik DG.

DNA Repair (Amst). 2009 Dec 3;8(12):1411-23. doi: 10.1016/j.dnarep.2009.09.011. Epub 2009 Oct 15.

14.

CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation.

Tate CM, Lee JH, Skalnik DG.

Mol Cell Biol. 2009 Jul;29(14):3817-31. doi: 10.1128/MCB.00243-09. Epub 2009 May 11.

15.

DNA Methyltransferase protein synthesis is reduced in CXXC finger protein 1-deficient embryonic stem cells.

Butler JS, Palam LR, Tate CM, Sanford JR, Wek RC, Skalnik DG.

DNA Cell Biol. 2009 May;28(5):223-31. doi: 10.1089/dna.2009.0854.

16.

Identification of a minimal cis-element and cognate trans-factor(s) required for induction of Rac2 gene expression during K562 cell differentiation.

Muthukrishnan R, Skalnik DG.

Gene. 2009 Jul 1;440(1-2):63-72. doi: 10.1016/j.gene.2009.04.005. Epub 2009 Apr 17.

17.

Methyl group acceptance assay for the determination of global DNA methylation levels.

Nephew KP, Balch C, Skalnik DG.

Methods Mol Biol. 2009;507:35-41. doi: 10.1007/978-1-59745-522-0_3.

PMID:
18987804
18.

CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes.

Butler JS, Lee JH, Skalnik DG.

DNA Cell Biol. 2008 Oct;27(10):533-43. doi: 10.1089/dna.2007.0714.

20.

Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex.

Lee JH, Tate CM, You JS, Skalnik DG.

J Biol Chem. 2007 May 4;282(18):13419-28. Epub 2007 Mar 13.

21.
22.

Antisense targeting of CXXC finger protein 1 inhibits genomic cytosine methylation and primitive hematopoiesis in zebrafish.

Young SR, Mumaw C, Marrs JA, Skalnik DG.

J Biol Chem. 2006 Dec 1;281(48):37034-44. Epub 2006 Oct 4.

23.

PAGE separation of hemi-methylated or unmethylated oligonucleotide substrates to distinguish between maintenance and de novo DNA methyltranferase activity.

Butler JS, Lee JH, Skalnik DG.

J Biochem Biophys Methods. 2006 Oct 31;68(3):195-9. Epub 2006 Jun 30.

PMID:
16901546
25.

Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer.

Balch C, Yan P, Craft T, Young S, Skalnik DG, Huang TH, Nephew KP.

Mol Cancer Ther. 2005 Oct;4(10):1505-14.

26.

Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein.

Carlone DL, Lee JH, Young SR, Dobrota E, Butler JS, Ruiz J, Skalnik DG.

Mol Cell Biol. 2005 Jun;25(12):4881-91.

28.

Histone deacetylase activity is required for embryonic stem cell differentiation.

Lee JH, Hart SR, Skalnik DG.

Genesis. 2004 Jan;38(1):32-8.

PMID:
14755802
29.

Identification of the human HEX1/hExo1 gene promoter and characterization of elements responsible for promoter activity.

Ladd PD, Wilson DM 3rd, Kelley MR, Skalnik DG.

DNA Repair (Amst). 2003 Feb 3;2(2):187-98.

PMID:
12531389
30.

Cloning and characterization of the gene encoding the mouse homologue of CpG binding protein.

Carlone DL, Hart SR, Ladd PD, Skalnik DG.

Gene. 2002 Jul 24;295(1):71-7.

PMID:
12242013
32.

Transcriptional mechanisms regulating myeloid-specific genes.

Skalnik DG.

Gene. 2002 Feb 6;284(1-2):1-21. Review.

PMID:
11891042
33.

CpG binding protein is crucial for early embryonic development.

Carlone DL, Skalnik DG.

Mol Cell Biol. 2001 Nov;21(22):7601-6.

34.
35.

Identification and characterization of the DNA binding domain of CpG-binding protein.

Lee JH, Voo KS, Skalnik DG.

J Biol Chem. 2001 Nov 30;276(48):44669-76. Epub 2001 Sep 25.

37.

DNA-binding properties of CCAAT displacement protein cut repeats.

Catt D, Luo W, Skalnik DG.

Cell Mol Biol (Noisy-le-grand). 1999 Dec;45(8):1149-60.

PMID:
10643964
38.

Overexpression of CCAAT displacement protein represses the promiscuously active proximal gp91(phox) promoter.

Catt D, Hawkins S, Roman A, Luo W, Skalnik DG.

Blood. 1999 Nov 1;94(9):3151-60.

PMID:
10556202
39.
41.

Identification and functional characterization of the murine Rac2 gene promoter.

Ou X, Pollock J, Dinauer MC, Gharehbaghi-Schnell E, Skalnik DG.

DNA Cell Biol. 1999 Mar;18(3):253-63.

PMID:
10098607
42.
44.

Interferon regulatory factor-2 directs transcription from the gp91phox promoter.

Luo W, Skalnik DG.

J Biol Chem. 1996 Sep 20;271(38):23445-51.

45.
47.
48.

Cloning of a cDNA encoding a human DNA-binding protein similar to ribosomal protein S1.

Eklund EA, Lee SW, Skalnik DG.

Gene. 1995 Apr 3;155(2):231-5.

PMID:
7721096
49.
50.

Sequence-specific binding of HMG-I (Y) to the proximal promoter of the gp91-phox gene.

Skalnik DG, Neufeld EJ.

Biochem Biophys Res Commun. 1993 Jan 15;190(1):308-9. No abstract available.

PMID:
8422257

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