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Items: 1 to 50 of 70

1.

Real-time optical redox imaging of cartilage metabolic response to mechanical loading.

Walsh SK, Skala MC, Henak CR.

Osteoarthritis Cartilage. 2019 Sep 9. pii: S1063-4584(19)31190-2. doi: 10.1016/j.joca.2019.08.004. [Epub ahead of print]

PMID:
31513919
2.

Tumor-on-a-chip: a microfluidic model to study cell response to environmental gradients.

Ayuso JM, Virumbrales-Munoz M, McMinn PH, Rehman S, Gomez I, Karim MR, Trusttchel R, Wisinski KB, Beebe DJ, Skala MC.

Lab Chip. 2019 Oct 9;19(20):3461-3471. doi: 10.1039/c9lc00270g.

PMID:
31506657
3.

Effects of culture method on response to EGFR therapy in head and neck squamous cell carcinoma cells.

Ayuso JM, Vitek R, Swick AD, Skala MC, Wisinski KB, Kimple RJ, Lambert PF, Beebe DJ.

Sci Rep. 2019 Aug 28;9(1):12480. doi: 10.1038/s41598-019-48764-3.

4.

Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation.

Pasch CA, Favreau PF, Yueh AE, Babiarz CP, Gillette AA, Sharick JT, Karim MR, Nickel KP, DeZeeuw AK, Sprackling CM, Emmerich PB, DeStefanis RA, Pitera RT, Payne SN, Korkos DP, Clipson L, Walsh CM, Miller D, Carchman EH, Burkard ME, Lemmon KK, Matkowskyj KA, Newton MA, Ong IM, Bassetti MF, Kimple RJ, Skala MC, Deming DA.

Clin Cancer Res. 2019 Sep 1;25(17):5376-5387. doi: 10.1158/1078-0432.CCR-18-3590. Epub 2019 Jun 7.

PMID:
31175091
5.

Photothermal Optical Coherence Tomography of Anti-Angiogenic Treatment in the Mouse Retina Using Gold Nanorods as Contrast Agents.

Gordon AY, Lapierre-Landry M, Skala MC, Penn JS.

Transl Vis Sci Technol. 2019 May 14;8(3):18. doi: 10.1167/tvst.8.3.18. eCollection 2019 May.

6.

Cellular Metabolic Heterogeneity In Vivo Is Recapitulated in Tumor Organoids.

Sharick JT, Jeffery JJ, Karim MR, Walsh CM, Esbona K, Cook RS, Skala MC.

Neoplasia. 2019 Jun;21(6):615-626. doi: 10.1016/j.neo.2019.04.004. Epub 2019 May 9.

7.

Imaging intratumoral metabolic heterogeneity.

Walsh AJ, Sharick JT, Skala MC.

Nat Biomed Eng. 2019 May;3(5):333-334. doi: 10.1038/s41551-019-0398-z. No abstract available.

PMID:
31073174
8.

Author Correction: Drug response in organoids generated from frozen primary tumor tissues.

Walsh AJ, Cook RS, Sanders ME, Arteaga CL, Skala MC.

Sci Rep. 2019 Apr 24;9(1):6517. doi: 10.1038/s41598-019-42133-w.

9.

Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model.

Ayuso JM, Truttschel R, Gong MM, Humayun M, Virumbrales-Munoz M, Vitek R, Felder M, Gillies SD, Sondel P, Wisinski KB, Patankar M, Beebe DJ, Skala MC.

Oncoimmunology. 2018 Dec 12;8(3):1553477. doi: 10.1080/2162402X.2018.1553477. eCollection 2019.

PMID:
30723584
10.

Redox imaging and optical coherence tomography of the respiratory ciliated epithelium.

Gil DA, Sharick JT, Mancha S, Gamm UA, Choma MA, Skala MC.

J Biomed Opt. 2019 Jan;24(1):1-4. doi: 10.1117/1.JBO.24.1.010501.

11.

Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines.

Capowski EE, Samimi K, Mayerl SJ, Phillips MJ, Pinilla I, Howden SE, Saha J, Jansen AD, Edwards KL, Jager LD, Barlow K, Valiauga R, Erlichman Z, Hagstrom A, Sinha D, Sluch VM, Chamling X, Zack DJ, Skala MC, Gamm DM.

Development. 2019 Jan 9;146(1). pii: dev171686. doi: 10.1242/dev.171686.

12.

Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels.

Kaushik G, Gil DA, Torr E, Berge ES, Soref C, Uhl P, Fontana G, Antosiewicz-Bourget J, Edington C, Schwartz MP, Griffith LG, Thomson JA, Skala MC, Daly WT, Murphy WL.

Adv Healthc Mater. 2019 Jan;8(2):e1801186. doi: 10.1002/adhm.201801186. Epub 2018 Dec 19.

13.

Imaging retinal melanin: a review of current technologies.

Lapierre-Landry M, Carroll J, Skala MC.

J Biol Eng. 2018 Dec 4;12:29. doi: 10.1186/s13036-018-0124-5. eCollection 2018. Review.

14.

Organotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations.

Ayuso JM, Gillette A, Lugo-Cintrón K, Acevedo-Acevedo S, Gomez I, Morgan M, Heaster T, Wisinski KB, Palecek SP, Skala MC, Beebe DJ.

EBioMedicine. 2018 Nov;37:144-157. doi: 10.1016/j.ebiom.2018.10.046. Epub 2018 Oct 26.

15.

MTORC1/2 Inhibition as a Therapeutic Strategy for PIK3CA Mutant Cancers.

Fricke SL, Payne SN, Favreau PF, Kratz JD, Pasch CA, Foley TM, Yueh AE, Van De Hey DR, Depke MG, Korkos DP, Sha GC, DeStefanis RA, Clipson L, Burkard ME, Lemmon KK, Parsons BM, Kenny PA, Matkowskyj KA, Newton MA, Skala MC, Deming DA.

Mol Cancer Ther. 2019 Feb;18(2):346-355. doi: 10.1158/1535-7163.MCT-18-0510. Epub 2018 Nov 13.

PMID:
30425131
16.

BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML.

Zhang S, Zhao Y, Heaster TM, Fischer MA, Stengel KR, Zhou X, Ramsey H, Zhou MM, Savona MR, Skala MC, Hiebert SW.

J Cell Biochem. 2018 Nov 11. doi: 10.1002/jcb.28005. [Epub ahead of print]

PMID:
30417424
17.

Drug-Free ROS Sponge Polymeric Microspheres Reduce Tissue Damage from Ischemic and Mechanical Injury.

O'Grady KP, Kavanaugh TE, Cho H, Ye H, Gupta MK, Madonna MC, Lee J, O'Brien CM, Skala MC, Hasty KA, Duvall CL.

ACS Biomater Sci Eng. 2018 Apr 9;4(4):1251-1264. doi: 10.1021/acsbiomaterials.6b00804. Epub 2017 Apr 6.

18.

Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography.

Lapierre-Landry M, Huckenpahler AL, Link BA, Collery RF, Carroll J, Skala MC.

Transl Vis Sci Technol. 2018 Sep 4;7(5):4. doi: 10.1167/tvst.7.5.4. eCollection 2018.

19.

Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells.

Zhang Q, Jeppesen DK, Higginbotham JN, Demory Beckler M, Poulin EJ, Walsh AJ, Skala MC, McKinley ET, Manning HC, Hight MR, Schulte ML, Watt KR, Ayers GD, Wolf MM, Andrejeva G, Rathmell JC, Franklin JL, Coffey RJ.

Cell Mol Gastroenterol Hepatol. 2018 Jan 31;5(4):627-629.e6. doi: 10.1016/j.jcmgh.2018.01.013. eCollection 2018. No abstract available.

20.

Photothermal optical coherence tomography of indocyanine green in ex vivo eyes.

Lapierre-Landry M, Connor TB, Carroll J, Tao YK, Skala MC.

Opt Lett. 2018 Jun 1;43(11):2470-2473. doi: 10.1364/OL.43.002470.

PMID:
29856406
21.

Quantifying optical properties with visible and near-infrared optical coherence tomography to visualize esophageal microwave ablation zones.

Niemeier RC, Etoz S, Gil DA, Skala MC, Brace CL, Rogers JD.

Biomed Opt Express. 2018 Mar 13;9(4):1648-1663. doi: 10.1364/BOE.9.001648. eCollection 2018 Apr 1.

22.

Protein-bound NAD(P)H Lifetime is Sensitive to Multiple Fates of Glucose Carbon.

Sharick JT, Favreau PF, Gillette AA, Sdao SM, Merrins MJ, Skala MC.

Sci Rep. 2018 Apr 3;8(1):5456. doi: 10.1038/s41598-018-23691-x.

23.

Oxidative stress via inhibition of the mitochondrial electron transport and Nrf-2-mediated anti-oxidative response regulate the cytotoxic activity of plumbagin.

Kapur A, Beres T, Rathi K, Nayak AP, Czarnecki A, Felder M, Gillette A, Ericksen SS, Sampene E, Skala MC, Barroilhet L, Patankar MS.

Sci Rep. 2018 Jan 18;8(1):1073. doi: 10.1038/s41598-018-19261-w.

24.

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.

Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, Kondo J, Coffey RJ, Johnson MO, Rathmell JC, Sharick JT, Skala MC, Smith JA, Berlin J, Washington MK, Nickels ML, Manning HC.

Nat Med. 2018 Feb;24(2):194-202. doi: 10.1038/nm.4464. Epub 2018 Jan 15.

25.

In vivo photothermal optical coherence tomography of endogenous and exogenous contrast agents in the eye.

Lapierre-Landry M, Gordon AY, Penn JS, Skala MC.

Sci Rep. 2017 Aug 23;7(1):9228. doi: 10.1038/s41598-017-10050-5.

26.

Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension.

Egnatchik RA, Brittain EL, Shah AT, Fares WH, Ford HJ, Monahan K, Kang CJ, Kocurek EG, Zhu S, Luong T, Nguyen TT, Hysinger E, Austin ED, Skala MC, Young JD, Roberts LJ 2nd, Hemnes AR, West J, Fessel JP.

Pulm Circ. 2017 Feb 1;7(1):186-199. doi: 10.1086/690236. eCollection 2017 Mar.

27.

Autofluorescence imaging captures heterogeneous drug response differences between 2D and 3D breast cancer cultures.

Cannon TM, Shah AT, Skala MC.

Biomed Opt Express. 2017 Feb 28;8(3):1911-1925. doi: 10.1364/BOE.8.001911. eCollection 2017 Mar 1.

28.

Functional Optical Imaging of Primary Human Tumor Organoids: Development of a Personalized Drug Screen.

Walsh AJ, Cook RS, Skala MC.

J Nucl Med. 2017 Sep;58(9):1367-1372. doi: 10.2967/jnumed.117.192534. Epub 2017 Jun 6. Review.

29.

Autofluorescence imaging identifies tumor cell-cycle status on a single-cell level.

Heaster TM, Walsh AJ, Zhao Y, Hiebert SW, Skala MC.

J Biophotonics. 2018 Jan;11(1). doi: 10.1002/jbio.201600276. Epub 2017 May 9.

30.

Metabolic Imaging of Head and Neck Cancer Organoids.

Shah AT, Heaster TM, Skala MC.

PLoS One. 2017 Jan 18;12(1):e0170415. doi: 10.1371/journal.pone.0170415. eCollection 2017.

31.

Autofluorescence flow sorting of breast cancer cell metabolism.

Shah AT, Cannon TM, Higginbotham JN, Coffey RJ, Skala MC.

J Biophotonics. 2017 Aug;10(8):1026-1033. doi: 10.1002/jbio.201600128. Epub 2016 Oct 12.

32.

Copolymer-Mediated Cell Aggregation Promotes a Proangiogenic Stem Cell Phenotype In Vitro and In Vivo.

Crowder SW, Balikov DA, Boire TC, McCormack D, Lee JB, Gupta MK, Skala MC, Sung HJ.

Adv Healthc Mater. 2016 Nov;5(22):2866-2871. doi: 10.1002/adhm.201600819. Epub 2016 Sep 26.

33.

Depth-resolved analytical model and correction algorithm for photothermal optical coherence tomography.

Lapierre-Landry M, Tucker-Schwartz JM, Skala MC.

Biomed Opt Express. 2016 Jun 16;7(7):2607-22. doi: 10.1364/BOE.7.002607. eCollection 2016 Jul 1.

34.

Temporal binning of time-correlated single photon counting data improves exponential decay fits and imaging speed.

Walsh AJ, Sharick JT, Skala MC, Beier HT.

Biomed Opt Express. 2016 Mar 18;7(4):1385-99. doi: 10.1364/BOE.7.001385. eCollection 2016 Apr 1.

35.

Drug response in organoids generated from frozen primary tumor tissues.

Walsh AJ, Cook RS, Sanders ME, Arteaga CL, Skala MC.

Sci Rep. 2016 Jan 7;6:18889. doi: 10.1038/srep18889. Erratum in: Sci Rep. 2019 Apr 24;9(1):6517.

36.

In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment.

Shah AT, Diggins KE, Walsh AJ, Irish JM, Skala MC.

Neoplasia. 2015 Dec;17(12):862-870. doi: 10.1016/j.neo.2015.11.006.

37.

Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response.

Walsh AJ, Castellanos JA, Nagathihalli NS, Merchant NB, Skala MC.

Pancreas. 2016 Jul;45(6):863-9. doi: 10.1097/MPA.0000000000000543.

38.

Deconvolution of fluorescence lifetime imaging microscopy by a library of exponentials.

Campos-Delgado DU, Navarro OG, Arce-Santana ER, Walsh AJ, Skala MC, Jo JA.

Opt Express. 2015 Sep 7;23(18):23748-67. doi: 10.1364/OE.23.023748.

39.

Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.

Nagathihalli NS, Castellanos JA, Shi C, Beesetty Y, Reyzer ML, Caprioli R, Chen X, Walsh AJ, Skala MC, Moses HL, Merchant NB.

Gastroenterology. 2015 Dec;149(7):1932-1943.e9. doi: 10.1053/j.gastro.2015.07.058. Epub 2015 Aug 7.

40.

Blind deconvolution estimation of fluorescence measurements through quadratic programming.

Campos-Delgado DU, Gutierrez-Navarro O, Arce-Santana ER, Skala MC, Walsh AJ, Jo JA.

J Biomed Opt. 2015 Jul;20(7):075010. doi: 10.1117/1.JBO.20.7.075010.

41.

Photothermal optical lock-in optical coherence tomography for in vivo imaging.

Tucker-Schwartz JM, Lapierre-Landry M, Patil CA, Skala MC.

Biomed Opt Express. 2015 May 27;6(6):2268-82. doi: 10.1364/BOE.6.002268. eCollection 2015 Jun 1.

42.

Optical metabolic imaging quantifies heterogeneous cell populations.

Walsh AJ, Skala MC.

Biomed Opt Express. 2015 Jan 15;6(2):559-73. doi: 10.1364/BOE.6.000559. eCollection 2015 Feb 1.

43.

Collagen density and alignment in responsive and resistant trastuzumab-treated breast cancer xenografts.

Walsh AJ, Cook RS, Lee JH, Arteaga CL, Skala MC.

J Biomed Opt. 2015 Feb;20(2):26004. doi: 10.1117/1.JBO.20.2.026004.

44.

High-throughput measurements of the optical redox ratio using a commercial microplate reader.

Cannon TM, Shah AT, Walsh AJ, Skala MC.

J Biomed Opt. 2015 Jan;20(1):010503. doi: 10.1117/1.JBO.20.1.010503.

45.

Quantifying the vascular response to ischemia with speckle variance optical coherence tomography.

Poole KM, McCormack DR, Patil CA, Duvall CL, Skala MC.

Biomed Opt Express. 2014 Nov 3;5(12):4118-30. doi: 10.1364/BOE.5.004118. eCollection 2014 Dec 1.

46.

ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease.

Poole KM, Nelson CE, Joshi RV, Martin JR, Gupta MK, Haws SC, Kavanaugh TE, Skala MC, Duvall CL.

Biomaterials. 2015 Feb;41:166-75. doi: 10.1016/j.biomaterials.2014.11.016. Epub 2014 Dec 9.

47.

Uncoupling angiogenesis and inflammation in peripheral artery disease with therapeutic peptide-loaded microgels.

Zachman AL, Wang X, Tucker-Schwartz JM, Fitzpatrick ST, Lee SH, Guelcher SA, Skala MC, Sung HJ.

Biomaterials. 2014 Dec;35(36):9635-48. doi: 10.1016/j.biomaterials.2014.08.011. Epub 2014 Aug 22.

48.

Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer.

Walsh AJ, Cook RS, Sanders ME, Aurisicchio L, Ciliberto G, Arteaga CL, Skala MC.

Cancer Res. 2014 Sep 15;74(18):5184-94. doi: 10.1158/0008-5472.CAN-14-0663. Epub 2014 Aug 6.

49.

In vivo hyperspectral imaging of microvessel response to trastuzumab treatment in breast cancer xenografts.

McCormack DR, Walsh AJ, Sit W, Arteaga CL, Chen J, Cook RS, Skala MC.

Biomed Opt Express. 2014 Jun 16;5(7):2247-61. doi: 10.1364/BOE.5.002247. eCollection 2014 Jul 1.

50.

In vivo imaging of nanoparticle delivery and tumor microvasculature with multimodal optical coherence tomography.

Tucker-Schwartz JM, Beavers KR, Sit WW, Shah AT, Duvall CL, Skala MC.

Biomed Opt Express. 2014 May 1;5(6):1731-43. doi: 10.1364/BOE.5.001731. eCollection 2014 Jun 1.

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