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Items: 1 to 50 of 745

1.

CENTRAL PRECOCIOUS PUBERTY IN TWO BOYS WITH PRADER-WILLI SYNDROME ON GROWTH HORMONE TREATMENT.

Monai E, Johansen A, Clasen-Linde E, Rajpert-De Meyts E, Skakkebæk NE, Main KM, Jørgensen A, Jensen RB.

AACE Clin Case Rep. 2019 Aug 15;5(6):e352-e356. doi: 10.4158/ACCR-2019-0245. eCollection 2019 Nov-Dec.

2.

Author Correction: Characterisation and localisation of the endocannabinoid system components in the adult human testis.

Nielsen JE, Rolland AD, Meyts ER, Janfelt C, Jørgensen A, Winge SB, Kristensen DM, Juul A, Chalmel F, Jégou B, Skakkebaek NE.

Sci Rep. 2020 Jan 22;10(1):1267. doi: 10.1038/s41598-020-58153-w.

3.

Testicular cancer incidence predictions in Europe 2010-2035: A rising burden despite population ageing.

Znaor A, Skakkebaek NE, Rajpert-De Meyts E, Laversanne M, Kuliš T, Gurney J, Sarfati D, McGlynn KA, Bray F.

Int J Cancer. 2019 Nov 26. doi: 10.1002/ijc.32810. [Epub ahead of print]

PMID:
31773729
4.

Changes in urinary excretion of phthalates, phthalate substitutes, bisphenols and other polychlorinated and phenolic substances in young Danish men; 2009-2017.

Frederiksen H, Nielsen O, Koch HM, Skakkebaek NE, Juul A, Jørgensen N, Andersson AM.

Int J Hyg Environ Health. 2020 Jan;223(1):93-105. doi: 10.1016/j.ijheh.2019.10.002. Epub 2019 Oct 25.

PMID:
31669154
5.

Characterisation and localisation of the endocannabinoid system components in the adult human testis.

Nielsen JE, Rolland AD, Rajpert-De Meyts E, Janfelt C, Jørgensen A, Winge SB, Kristensen DM, Juul A, Chalmel F, Jégou B, Skakkebaek NE.

Sci Rep. 2019 Sep 19;9(1):12866. doi: 10.1038/s41598-019-49177-y. Erratum in: Sci Rep. 2020 Jan 22;10(1):1267.

6.

High maternal age at first and subsequent child births in Denmark in the mid-1800s-Letter to the editor.

Priskorn L, Dahl CL, Pihl AS, Skakkebaek NE, Juul A.

Eur J Obstet Gynecol Reprod Biol. 2019 Oct;241:137-138. doi: 10.1016/j.ejogrb.2019.09.005. Epub 2019 Sep 9. No abstract available.

PMID:
31530417
7.

Bone mineral density is preserved in men with idiopathic infertility.

Antonio L, Priskorn L, Nordkap L, Bang AK, Jensen TK, Skakkebaek NE, Petersen JH, Vanderschueren D, Jørgensen N.

Andrology. 2019 Aug 2. doi: 10.1111/andr.12688. [Epub ahead of print]

PMID:
31373436
8.

Proposed Key Characteristics of Male Reproductive Toxicants as an Approach for Organizing and Evaluating Mechanistic Evidence in Human Health Hazard Assessments.

Arzuaga X, Smith MT, Gibbons CF, Skakkebæk NE, Yost EE, Beverly BEJ, Hotchkiss AK, Hauser R, Pagani RL, Schrader SM, Zeise L, Prins GS.

Environ Health Perspect. 2019 Jun;127(6):65001. doi: 10.1289/EHP5045. Epub 2019 Jun 14.

9.

The association between in-utero exposure to stressful life events during pregnancy and male reproductive function in a cohort of 20-year-old offspring: The Raine Study.

Bräuner EV, Hansen ÅM, Doherty DA, Dickinson JE, Handelsman DJ, Hickey M, Skakkebæk NE, Juul A, Hart R.

Hum Reprod. 2019 Jul 8;34(7):1345-1355. doi: 10.1093/humrep/dez070.

PMID:
31143949
10.

Semen quality of young men in Switzerland: a nationwide cross-sectional population-based study.

Rahban R, Priskorn L, Senn A, Stettler E, Galli F, Vargas J, Van den Bergh M, Fusconi A, Garlantezec R, Jensen TK, Multigner L, Skakkebaek NE, Germond M, Jørgensen N, Nef S; NICER Working Group.

Andrology. 2019 Nov;7(6):818-826. doi: 10.1111/andr.12645. Epub 2019 May 21.

11.

Populations, decreasing fertility, and reproductive health.

Skakkebaek NE, Jørgensen N, Andersson AM, Juul A, Main KM, Jensen TK, Toppari J.

Lancet. 2019 Apr 13;393(10180):1500-1501. doi: 10.1016/S0140-6736(19)30690-7. No abstract available.

PMID:
30983583
12.

Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm.

Rehfeld A, Egeberg Palme DL, Almstrup K, Juul A, Skakkebaek NE.

J Vis Exp. 2019 Mar 1;(145). doi: 10.3791/59212.

PMID:
30882783
13.

Why Do Normal Children Have Acromegalic Levels of IGF-I During Puberty?

Juul A, Skakkebæk NE.

J Clin Endocrinol Metab. 2019 Jul 1;104(7):2770-2776. doi: 10.1210/jc.2018-02099.

PMID:
30840065
14.

Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy.

Assens M, Frederiksen H, Petersen JH, Larsen T, Skakkebæk NE, Juul A, Andersson AM, Main KM.

Environ Int. 2019 Feb;123:318-324. doi: 10.1016/j.envint.2018.11.047. Epub 2018 Dec 14.

15.

Anogenital distance is associated with semen quality but not reproductive hormones in 1106 young men from the general population.

Priskorn L, Bang AK, Nordkap L, Krause M, Mendiola J, Jensen TK, Juul A, Skakkebaek NE, Swan SH, Jørgensen N.

Hum Reprod. 2019 Jan 1;34(1):12-24. doi: 10.1093/humrep/dey326.

16.

Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis.

Jørgensen A, Macdonald J, Nielsen JE, Kilcoyne KR, Perlman S, Lundvall L, Langhoff Thuesen L, Juul Hare K, Frederiksen H, Andersson AM, Skakkebæk NE, Juul A, Sharpe RM, Rajpert-De Meyts E, Mitchell RT.

Cell Rep. 2018 Nov 13;25(7):1924-1937.e4. doi: 10.1016/j.celrep.2018.10.064.

17.

An update on semen quality among young Finnish men and comparison with Danish data.

Rodprasert W, Virtanen HE, Sadov S, Perheentupa A, Skakkebaek NE, Jørgensen N, Toppari J.

Andrology. 2019 Jan;7(1):15-23. doi: 10.1111/andr.12550. Epub 2018 Sep 24.

18.

Synergistic activation of CatSper Ca2+ channels in human sperm by oviductal ligands and endocrine disrupting chemicals.

Brenker C, Rehfeld A, Schiffer C, Kierzek M, Kaupp UB, Skakkebæk NE, Strünker T.

Hum Reprod. 2018 Oct 1;33(10):1915-1923. doi: 10.1093/humrep/dey275.

PMID:
30189007
19.

Dibutyl-phthalate exposure from mesalamine medications and serum thyroid hormones in men.

Nassan FL, Korevaar TIM, Coull BA, Skakkebæk NE, Krawetz SA, Estill M, Hait EJ, Korzenik JR, Ford JB, De Poortere RA, Broeren MA, Moss AC, Zoeller TR, Hauser R.

Int J Hyg Environ Health. 2019 Jan;222(1):101-110. doi: 10.1016/j.ijheh.2018.08.008. Epub 2018 Aug 28.

20.

Association of In Utero Persistent Organic Pollutant Exposure With Placental Thyroid Hormones.

Li ZM, Hernandez-Moreno D, Main KM, Skakkebæk NE, Kiviranta H, Toppari J, Feldt-Rasmussen U, Shen H, Schramm KW, De Angelis M.

Endocrinology. 2018 Oct 1;159(10):3473-3481. doi: 10.1210/en.2018-00542.

PMID:
30059991
21.

Quantification of the Leydig cell compartment in testicular biopsies and association with biochemical Leydig cell dysfunction in testicular cancer survivors.

Tarsitano MG, Bandak M, Jørgensen N, Skakkebaek NE, Juul A, Lenzi A, Daugaard G, Rajpert-De Meyts E.

Andrology. 2018 Sep;6(5):748-755. doi: 10.1111/andr.12508. Epub 2018 Jul 6.

22.

The Possible Impact of Antenatal Exposure to Ubiquitous Phthalates Upon Male Reproductive Function at 20 Years of Age.

Hart RJ, Frederiksen H, Doherty DA, Keelan JA, Skakkebaek NE, Minaee NS, McLachlan R, Newnham JP, Dickinson JE, Pennell CE, Norman RJ, Main KM.

Front Endocrinol (Lausanne). 2018 Jun 4;9:288. doi: 10.3389/fendo.2018.00288. eCollection 2018.

23.

Parental occupational exposure to solvents and heavy metals and risk of developing testicular germ cell tumors in sons (NORD-TEST Denmark).

Olsson A, Togawa K, Schüz J, Le Cornet C, Fervers B, Oksbjerg Dalton S, Pukkala E, Maria Feychting MF, Skakkebæk NE, Hansen J.

Scand J Work Environ Health. 2018 Nov 1;44(6):658-669. doi: 10.5271/sjweh.3732. Epub 2018 Jun 7.

PMID:
29877553
24.

Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells.

Winge SB, Dalgaard MD, Belling KG, Jensen JM, Nielsen JE, Aksglaede L, Schierup MH, Brunak S, Skakkebæk NE, Juul A, Rajpert-De Meyts E, Almstrup K.

Cell Death Dis. 2018 May 22;9(6):586. doi: 10.1038/s41419-018-0671-1.

25.

Average sperm count remains unchanged despite reduction in maternal smoking: results from a large cross-sectional study with annual investigations over 21 years.

Priskorn L, Nordkap L, Bang AK, Krause M, Holmboe SA, Egeberg Palme DL, Winge SB, Mørup N, Carlsen E, Joensen UN, Blomberg Jensen M, Main KM, Juul A, Skakkebaek NE, Jensen TK, Jørgensen N.

Hum Reprod. 2018 Jun 1;33(6):998-1008. doi: 10.1093/humrep/dey090.

PMID:
29659832
26.

Postnatal Changes in Testicular Position Are Associated With IGF-I and Function of Sertoli and Leydig Cells.

Koskenniemi JJ, Virtanen HE, Wohlfahrt-Veje C, Löyttyniemi E, Skakkebaek NE, Juul A, Andersson AM, Main KM, Toppari J.

J Clin Endocrinol Metab. 2018 Apr 1;103(4):1429-1437. doi: 10.1210/jc.2017-01889.

PMID:
29408984
27.

Maternal exposure to UV filters: associations with maternal thyroid hormones, IGF-I/IGFBP3 and birth outcomes.

Krause M, Frederiksen H, Sundberg K, Jørgensen FS, Jensen LN, Nørgaard P, Jørgensen C, Ertberg P, Petersen JH, Feldt-Rasmussen U, Juul A, Drzewiecki KT, Skakkebaek NE, Andersson AM.

Endocr Connect. 2018 Feb;7(2):334-346. doi: 10.1530/EC-17-0375. Epub 2018 Jan 23.

28.

Determination of thyroid hormones in placenta using isotope-dilution liquid chromatography quadrupole time-of-flight mass spectrometry.

Li ZM, Giesert F, Vogt-Weisenhorn D, Main KM, Skakkebæk NE, Kiviranta H, Toppari J, Feldt-Rasmussen U, Shen H, Schramm KW, De Angelis M.

J Chromatogr A. 2018 Jan 26;1534:85-92. doi: 10.1016/j.chroma.2017.12.048. Epub 2017 Dec 24.

PMID:
29307529
29.

Viable acrosome-intact human spermatozoa in the ejaculate as a marker of semen quality and fertility status.

Egeberg Palme DL, Rehfeld A, Bang AK, Nikolova KA, Kjærulff S, Petersen MR, Jeppesen JV, Glensbjerg M, Juul A, Skakkebæk NE, Ziebe S, Jørgensen N, Almstrup K.

Hum Reprod. 2018 Mar 1;33(3):361-371. doi: 10.1093/humrep/dex380.

PMID:
29304248
30.

Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?

Bang AK, Busch AS, Almstrup K, Gromoll J, Kliesch S, Rajpert-De Meyts E, Skakkebaek NE, Juul A, Tüttelmann F, Jørgensen N.

Andrology. 2018 Jan;6(1):176-183. doi: 10.1111/andr.12440. Epub 2017 Nov 27.

31.

Anogenital distance as a phenotypic signature through infancy.

Priskorn L, Petersen JH, Jørgensen N, Kyhl HB, Andersen MS, Main KM, Andersson AM, Skakkebaek NE, Jensen TK.

Pediatr Res. 2018 Mar;83(3):573-579. doi: 10.1038/pr.2017.287. Epub 2017 Dec 20.

PMID:
29155806
32.

Presence of benzophenones commonly used as UV filters and absorbers in paired maternal and fetal samples.

Krause M, Frederiksen H, Sundberg K, Jørgensen FS, Jensen LN, Nørgaard P, Jørgensen C, Ertberg P, Juul A, Drzewiecki KT, Skakkebaek NE, Andersson AM.

Environ Int. 2018 Jan;110:51-60. doi: 10.1016/j.envint.2017.10.005.

PMID:
29100749
33.

Individual testosterone decline and future mortality risk in men.

Holmboe SA, Skakkebæk NE, Juul A, Scheike T, Jensen TK, Linneberg A, Thuesen BH, Andersson AM.

Eur J Endocrinol. 2018 Jan;178(1):123-130. doi: 10.1530/EJE-17-0280. Epub 2017 Oct 24.

PMID:
29066571
34.

Germ Cell Neoplasia in Situ and Preserved Fertility Despite Suppressed Gonadotropins in a Patient With Testotoxicosis.

Juel Mortensen L, Blomberg Jensen M, Christiansen P, Rønholt AM, Jørgensen A, Frederiksen H, Nielsen JE, Loya AC, Grønkær Toft B, Skakkebæk NE, Rajpert-De Meyts E, Juul A.

J Clin Endocrinol Metab. 2017 Dec 1;102(12):4411-4416. doi: 10.1210/jc.2017-01761.

PMID:
29029242
35.

Sperm counts, testicular cancers, and the environment.

Skakkebaek NE.

BMJ. 2017 Oct 10;359:j4517. doi: 10.1136/bmj.j4517. No abstract available.

PMID:
29017996
36.

Possible involvement of the glucocorticoid receptor (NR3C1) and selected NR3C1 gene variants in regulation of human testicular function.

Nordkap L, Almstrup K, Nielsen JE, Bang AK, Priskorn L, Krause M, Holmboe SA, Winge SB, Egeberg Palme DL, Mørup N, Petersen JH, Juul A, Skakkebaek NE, Rajpert-De Meyts E, Jørgensen N.

Andrology. 2017 Nov;5(6):1105-1114. doi: 10.1111/andr.12418. Epub 2017 Oct 9.

37.

A crossover-crossback prospective study of dibutyl-phthalate exposure from mesalamine medications and serum reproductive hormones in men.

Nassan FL, Coull BA, Skakkebaek NE, Andersson AM, Williams MA, Mínguez-Alarcón L, Krawetz SA, Hall JE, Hait EJ, Korzenik JR, Ford JB, Moss AC, Hauser R.

Environ Res. 2018 Jan;160:121-131. doi: 10.1016/j.envres.2017.09.025. Epub 2017 Oct 1.

38.

Parental Occupational Exposure to Organic Solvents and Testicular Germ Cell Tumors in their Offspring: NORD-TEST Study.

Le Cornet C, Fervers B, Pukkala E, Tynes T, Feychting M, Hansen J, Togawa K, Nordby KC, Oksbjerg Dalton S, Uuksulainen S, Wiebert P, Woldbæk T, Skakkebæk NE, Olsson A, Schüz J.

Environ Health Perspect. 2017 Jun 30;125(6):067023. doi: 10.1289/EHP864.

39.

Personal Care Product Use in Men and Urinary Concentrations of Select Phthalate Metabolites and Parabens: Results from the Environment And Reproductive Health (EARTH) Study.

Nassan FL, Coull BA, Gaskins AJ, Williams MA, Skakkebaek NE, Ford JB, Ye X, Calafat AM, Braun JM, Hauser R.

Environ Health Perspect. 2017 Aug 18;125(8):087012. doi: 10.1289/EHP1374.

40.

EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner.

Rehfeld A, Egeberg DL, Almstrup K, Petersen JH, Dissing S, Skakkebæk NE.

Endocr Connect. 2018 Jan;7(1):16-25. doi: 10.1530/EC-17-0156. Epub 2017 Sep 5.

41.

Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study.

Mogensen DM, Pihl MB, Skakkebæk NE, Andersen HR, Juul A, Kyhl HB, Swan S, Kristensen DM, Andersen MS, Lind DV, Jensen TK.

Environ Health. 2017 Jun 21;16(1):68. doi: 10.1186/s12940-017-0263-z.

42.

Exposure to phenols, parabens and UV filters: Associations with loss-of-function mutations in the filaggrin gene in men from the general population.

Joensen UN, Jørgensen N, Thyssen JP, Petersen JH, Szecsi PB, Stender S, Andersson AM, Skakkebæk NE, Frederiksen H.

Environ Int. 2017 Aug;105:105-111. doi: 10.1016/j.envint.2017.05.013. Epub 2017 May 17.

PMID:
28525834
43.

Influence of marital status on testosterone levels-A ten year follow-up of 1113 men.

Holmboe SA, Priskorn L, Jørgensen N, Skakkebaek NE, Linneberg A, Juul A, Andersson AM.

Psychoneuroendocrinology. 2017 Jun;80:155-161. doi: 10.1016/j.psyneuen.2017.03.010. Epub 2017 Mar 10.

PMID:
28376340
44.

Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity.

Belling K, Russo F, Jensen AB, Dalgaard MD, Westergaard D, Rajpert-De Meyts E, Skakkebæk NE, Juul A, Brunak S.

Hum Mol Genet. 2017 Apr 1;26(7):1219-1229. doi: 10.1093/hmg/ddx014.

45.

Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window.

van den Driesche S, Kilcoyne KR, Wagner I, Rebourcet D, Boyle A, Mitchell R, McKinnell C, Macpherson S, Donat R, Shukla CJ, Jorgensen A, Meyts ER, Skakkebaek NE, Sharpe RM.

JCI Insight. 2017 Mar 23;2(6):e91204. doi: 10.1172/jci.insight.91204.

46.

Assumed non-persistent environmental chemicals in human adipose tissue; matrix stability and correlation with levels measured in urine and serum.

Artacho-Cordón F, Arrebola JP, Nielsen O, Hernández P, Skakkebaek NE, Fernández MF, Andersson AM, Olea N, Frederiksen H.

Environ Res. 2017 Jul;156:120-127. doi: 10.1016/j.envres.2017.03.030. Epub 2017 Mar 22.

PMID:
28342347
47.

Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents.

Lottrup G, Belling K, Leffers H, Nielsen JE, Dalgaard MD, Juul A, Skakkebæk NE, Brunak S, Rajpert-De Meyts E.

Mol Hum Reprod. 2017 May 1;23(5):339-354. doi: 10.1093/molehr/gax012.

PMID:
28333300
48.

Validation of image cytometry for sperm concentration measurement: Comparison with manual counting of 4010 human semen samples.

Egeberg Palme DL, Johannsen TH, Petersen JH, Skakkebæk NE, Juul A, Jørgensen N, Almstrup K.

Clin Chim Acta. 2017 May;468:114-119. doi: 10.1016/j.cca.2017.02.014. Epub 2017 Feb 27.

PMID:
28242391
49.

Leydig cell clustering and Reinke crystal distribution in relation to hormonal function in adult patients with testicular dysgenesis syndrome (TDS) including cryptorchidism.

Soerensen RR, Johannsen TH, Skakkebaek NE, Rajpert-De Meyts E.

Hormones (Athens). 2016 Oct;15(4):518-526. doi: 10.14310/horm.2002.1708.

50.

Chromosome-wise Protein Interaction Patterns and Their Impact on Functional Implications of Large-Scale Genomic Aberrations.

Kirk IK, Weinhold N, Belling K, Skakkebæk NE, Jensen TS, Leffers H, Juul A, Brunak S.

Cell Syst. 2017 Mar 22;4(3):357-364.e3. doi: 10.1016/j.cels.2017.01.001. Epub 2017 Feb 15.

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