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Items: 21


MAGI-2 scaffold protein is critical for kidney barrier function.

Balbas MD, Burgess MR, Murali R, Wongvipat J, Skaggs BJ, Mundel P, Weins A, Sawyers CL.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14876-81. doi: 10.1073/pnas.1417297111. Epub 2014 Sep 30.


Laquinimod delays and suppresses nephritis in lupus-prone mice and affects both myeloid and lymphoid immune cells.

Lourenço EV, Wong M, Hahn BH, Palma-Diaz MF, Skaggs BJ.

Arthritis Rheumatol. 2014 Mar;66(3):674-85. doi: 10.1002/art.38259.


A panel of biomarkers is associated with increased risk of the presence and progression of atherosclerosis in women with systemic lupus erythematosus.

McMahon M, Skaggs BJ, Grossman JM, Sahakian L, Fitzgerald J, Wong WK, Lourenco EV, Ragavendra N, Charles-Schoeman C, Gorn A, Karpouzas GA, Taylor MB, Watson KE, Weisman MH, Wallace DJ, Hahn BH.

Arthritis Rheumatol. 2014 Jan;66(1):130-9. doi: 10.1002/art.38204.


Accelerated atherosclerosis in patients with SLE--mechanisms and management.

Skaggs BJ, Hahn BH, McMahon M.

Nat Rev Rheumatol. 2012 Feb 14;8(4):214-23. doi: 10.1038/nrrheum.2012.14. Review.


High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids.

McMahon M, Skaggs BJ, Sahakian L, Grossman J, FitzGerald J, Ragavendra N, Charles-Schoeman C, Chernishof M, Gorn A, Witztum JL, Wong WK, Weisman M, Wallace DJ, La Cava A, Hahn BH.

Ann Rheum Dis. 2011 Sep;70(9):1619-24. doi: 10.1136/ard.2010.142737. Epub 2011 Jun 13.


Systemic lupus erythematosus and cardiovascular disease: prediction and potential for therapeutic intervention.

McMahon M, Hahn BH, Skaggs BJ.

Expert Rev Clin Immunol. 2011 Mar;7(2):227-41. doi: 10.1586/eci.10.98. Review.


Dysfunctional, pro-inflammatory HDL directly upregulates monocyte PDGFRβ, chemotaxis and TNFα production.

Skaggs BJ, Hahn BH, Sahakian L, Grossman J, McMahon M.

Clin Immunol. 2010 Oct;137(1):147-56. doi: 10.1016/j.clim.2010.06.014. Epub 2010 Jul 15.


CD8+ Tregs in lupus, autoimmunity, and beyond.

Dinesh RK, Skaggs BJ, La Cava A, Hahn BH, Singh RP.

Autoimmun Rev. 2010 Jun;9(8):560-8. doi: 10.1016/j.autrev.2010.03.006. Epub 2010 Apr 10. Review.


Maximal entropy inference of oncogenicity from phosphorylation signaling.

Graeber TG, Heath JR, Skaggs BJ, Phelps ME, Remacle F, Levine RD.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6112-7. doi: 10.1073/pnas.1001149107. Epub 2010 Mar 11.


Low physical activity is associated with proinflammatory high-density lipoprotein and increased subclinical atherosclerosis in women with systemic lupus erythematosus.

Volkmann ER, Grossman JM, Sahakian LJ, Skaggs BJ, FitzGerald J, Ragavendra N, Charles-Schoeman C, Chen W, Gorn A, Karpouzas G, Weisman M, Wallace DJ, Hahn BH, McMahon M.

Arthritis Care Res (Hoboken). 2010 Feb;62(2):258-65. doi: 10.1002/acr.20076.


Altered lipoprotein metabolism in chronic inflammatory states: proinflammatory high-density lipoprotein and accelerated atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis.

Hahn BH, Grossman J, Ansell BJ, Skaggs BJ, McMahon M.

Arthritis Res Ther. 2008;10(4):213. doi: 10.1186/ar2471. Epub 2008 Aug 29. Review.


Induction of immune tolerance by activation of CD8+ T suppressor/regulatory cells in lupus-prone mice.

Skaggs BJ, Singh RP, Hahn BH.

Hum Immunol. 2008 Nov;69(11):790-6. doi: 10.1016/j.humimm.2008.08.284. Epub 2008 Sep 24. Review.


IkappaB kinase beta inhibition induces cell death in Imatinib-resistant and T315I Dasatinib-resistant BCR-ABL+ cells.

Duncan EA, Goetz CA, Stein SJ, Mayo KJ, Skaggs BJ, Ziegelbauer K, Sawyers CL, Baldwin AS.

Mol Cancer Ther. 2008 Feb;7(2):391-7. doi: 10.1158/1535-7163.MCT-07-0305. Epub 2008 Feb 1.


Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency.

Shah NP, Skaggs BJ, Branford S, Hughes TP, Nicoll JM, Paquette RL, Sawyers CL.

J Clin Invest. 2007 Sep;117(9):2562-9.


Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants.

Skaggs BJ, Gorre ME, Ryvkin A, Burgess MR, Xie Y, Han Y, Komisopoulou E, Brown LM, Loo JA, Landaw EM, Sawyers CL, Graeber TG.

Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19466-71. Epub 2006 Dec 12.


Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance.

Burgess MR, Skaggs BJ, Shah NP, Lee FY, Sawyers CL.

Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3395-400. Epub 2005 Feb 10.


The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways.

Kabak S, Skaggs BJ, Gold MR, Affolter M, West KL, Foster MS, Siemasko K, Chan AC, Aebersold R, Clark MR.

Mol Cell Biol. 2002 Apr;22(8):2524-35.


Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha.

Siemasko K, Skaggs BJ, Kabak S, Williamson E, Brown BK, Song W, Clark MR.

J Immunol. 2002 Mar 1;168(5):2127-38.


Grassroots lobbying: a nurse's responsibility.

Skaggs BJ.

Am Nurse. 1994 Oct;26(9):5-6. No abstract available.


Moving from corkboard to an electronic bulletin board for nursing.

Skaggs BJ.

Am J Nurs. 1989 Jun;89(6):858. No abstract available.


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