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Items: 19


Generation of a PAX6 knockout glioblastoma cell line with changes in cell cycle distribution and sensitivity to oxidative stress.

Hegge B, Sjøttem E, Mikkola I.

BMC Cancer. 2018 May 2;18(1):496. doi: 10.1186/s12885-018-4394-6.


TRIM50 regulates Beclin 1 proautophagic activity.

Fusco C, Mandriani B, Di Rienzo M, Micale L, Malerba N, Cocciadiferro D, Sjøttem E, Augello B, Squeo GM, Pellico MT, Jain A, Johansen T, Fimia GM, Merla G.

Biochim Biophys Acta Mol Cell Res. 2018 Jun;1865(6):908-919. doi: 10.1016/j.bbamcr.2018.03.011. Epub 2018 Mar 29.


FKBP8 recruits LC3A to mediate Parkin-independent mitophagy.

Bhujabal Z, Birgisdottir ÅB, Sjøttem E, Brenne HB, Øvervatn A, Habisov S, Kirkin V, Lamark T, Johansen T.

EMBO Rep. 2017 Jun;18(6):947-961. doi: 10.15252/embr.201643147. Epub 2017 Apr 5.


ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.

Skytte Rasmussen M, Mouilleron S, Kumar Shrestha B, Wirth M, Lee R, Bowitz Larsen K, Abudu Princely Y, O'Reilly N, Sjøttem E, Tooze SA, Lamark T, Johansen T.

Autophagy. 2017 May 4;13(5):834-853. doi: 10.1080/15548627.2017.1287651. Epub 2017 Feb 15.


p62/Sequestosome-1, Autophagy-related Gene 8, and Autophagy in Drosophila Are Regulated by Nuclear Factor Erythroid 2-related Factor 2 (NRF2), Independent of Transcription Factor TFEB.

Jain A, Rusten TE, Katheder N, Elvenes J, Bruun JA, Sjøttem E, Lamark T, Johansen T.

J Biol Chem. 2015 Jun 12;290(24):14945-62. doi: 10.1074/jbc.M115.656116. Epub 2015 Apr 30.


SPBP is a sulforaphane induced transcriptional coactivator of NRF2 regulating expression of the autophagy receptor p62/SQSTM1.

Darvekar SR, Elvenes J, Brenne HB, Johansen T, Sjøttem E.

PLoS One. 2014 Jan 9;9(1):e85262. doi: 10.1371/journal.pone.0085262. eCollection 2014.


A phylogenetic study of SPBP and RAI1: evolutionary conservation of chromatin binding modules.

Darvekar S, Rekdal C, Johansen T, Sjøttem E.

PLoS One. 2013 Oct 18;8(10):e78907. doi: 10.1371/journal.pone.0078907. eCollection 2013.


Identification of two independent nucleosome-binding domains in the transcriptional co-activator SPBP.

Darvekar S, Johnsen SS, Eriksen AB, Johansen T, Sjøttem E.

Biochem J. 2012 Feb 15;442(1):65-75. doi: 10.1042/BJ20111230.


Pax6 represses androgen receptor-mediated transactivation by inhibiting recruitment of the coactivator SPBP.

Elvenes J, Thomassen EI, Johnsen SS, Kaino K, Sjøttem E, Johansen T.

PLoS One. 2011;6(9):e24659. doi: 10.1371/journal.pone.0024659. Epub 2011 Sep 15.


Transforming growth factor-β-inducible early response gene 1 is a novel substrate for atypical protein kinase Cs.

Alemu EA, Sjøttem E, Outzen H, Larsen KB, Holm T, Bjørkøy G, Johansen T.

Cell Mol Life Sci. 2011 Jun;68(11):1953-68. doi: 10.1007/s00018-010-0541-1. Epub 2010 Oct 17.


Pax6 localizes to chromatin-rich territories and displays a slow nuclear mobility altered by disease mutations.

Elvenes J, Sjøttem E, Holm T, Bjørkøy G, Johansen T.

Cell Mol Life Sci. 2010 Dec;67(23):4079-94. doi: 10.1007/s00018-010-0429-0. Epub 2010 Jun 25.


p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.

Jain A, Lamark T, Sjøttem E, Larsen KB, Awuh JA, Øvervatn A, McMahon M, Hayes JD, Johansen T.

J Biol Chem. 2010 Jul 16;285(29):22576-91. doi: 10.1074/jbc.M110.118976. Epub 2010 May 7.


The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription.

Sjøttem E, Rekdal C, Svineng G, Johnsen SS, Klenow H, Uglehus RD, Johansen T.

Nucleic Acids Res. 2007;35(19):6648-62. Epub 2007 Oct 2.


In vivo expression of a group I intron HEG from the antisense strand of Didymium ribosomal DNA.

Johansen SD, Vader A, Sjøttem E, Nielsen H.

RNA Biol. 2006 Oct;3(4):157-62. Epub 2006 Oct 5.


The recent transfer of a homing endonuclease gene.

Haugen P, Wikmark OG, Vader A, Coucheron DH, Sjøttem E, Johansen SD.

Nucleic Acids Res. 2005 May 12;33(8):2734-41. Print 2005.


Structural and functional analyses of DNA bending induced by Sp1 family transcription factors.

Sjøttem E, Andersen C, Johansen T.

J Mol Biol. 1997 Apr 4;267(3):490-504.


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