Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 42

1.

Correction: A 32 kb Critical Region Excluding Y402H in CFH Mediates Risk for Age-Related Macular Degeneration.

Sivakumaran TA, Igo RP Jr, Kidd JM, Itsara A, Kopplin LJ, Chen W, Hagstrom SA, Peachey NS, Francis PJ, Klein ML, Chew EY, Ramprasad VL, Tay WT, Mitchell P, Seielstad M, Stambolian DE, Edwards AO, Lee KE, Leontiev DV, Jun G, Wang Y, Tian L, Qiu F, Henning AK, LaFramboise T, Sen P, Aarthi M, George R, Raman R, Das MK, Vijaya L, Kumaramanickavel G, Wong TY, Swaroop A, Abecasis GR, Klein R, Klein BEK, Nickerson DA, Eichler EE, Iyengar SK.

PLoS One. 2018 Dec 20;13(12):e0209943. doi: 10.1371/journal.pone.0209943. eCollection 2018.

2.

Characterization of Squamous Cell Lung Cancers from Appalachian Kentucky.

Liu J, Murali T, Yu T, Liu C, Sivakumaran TA, Moseley HNB, Zhulin IB, Weiss HL, Durbin EB, Ellingson SR, Liu J, Huang B, Hallahan BJ, Horbinski CM, Hodges K, Napier DL, Bocklage T, Mueller J, Vanderford NL, Fardo DW, Wang C, Arnold SM.

Cancer Epidemiol Biomarkers Prev. 2019 Feb;28(2):348-356. doi: 10.1158/1055-9965.EPI-17-0984. Epub 2018 Oct 30.

PMID:
30377206
3.

Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer.

Zaytseva YY, Rychahou PG, Le AT, Scott TL, Flight RM, Kim JT, Harris J, Liu J, Wang C, Morris AJ, Sivakumaran TA, Fan T, Moseley H, Gao T, Lee EY, Weiss HL, Heuer TS, Kemble G, Evers M.

Oncotarget. 2018 May 15;9(37):24787-24800. doi: 10.18632/oncotarget.25361. eCollection 2018 May 15.

4.

Small Drusen and Age-Related Macular Degeneration: The Beaver Dam Eye Study.

Klein R, Myers CE, Lee KE, Gangnon RE, Sivakumaran TA, Iyengar SK, Klein BE.

J Clin Med. 2015 Mar;4(3):424-40. doi: 10.3390/jcm4030425.

5.

Severity of age-related macular degeneration in 1 eye and the incidence and progression of age-related macular degeneration in the fellow eye: the Beaver Dam Eye Study.

Gangnon RE, Lee KE, Klein BE, Iyengar SK, Sivakumaran TA, Klein R.

JAMA Ophthalmol. 2015 Feb;133(2):125-32. doi: 10.1001/jamaophthalmol.2014.4252.

6.

Sunlight exposure, pigmentation, and incident age-related macular degeneration.

Klein BE, Howard KP, Iyengar SK, Sivakumaran TA, Meyers KJ, Cruickshanks KJ, Klein R.

Invest Ophthalmol Vis Sci. 2014 Aug 14;55(9):5855-61. doi: 10.1167/iovs.14-14602.

7.

Hematogones in the peripheral blood of a 5½-month-old boy with cyclic neutropenia due to heterozygous, novel ELANE gene mutation p.Q97P, c.290 A>C.

Juranovic T, O'Suoji CC, Sivakumaran TA, Zhang K, Estallila OC, Jelic TM.

Pediatr Dev Pathol. 2014 Sep-Oct;17(5):393-9. doi: 10.2350/14-03-1448-CR.1. Epub 2014 Jul 14.

PMID:
25019553
8.

Cigarette smoking and the natural history of age-related macular degeneration: the Beaver Dam Eye Study.

Myers CE, Klein BE, Gangnon R, Sivakumaran TA, Iyengar SK, Klein R.

Ophthalmology. 2014 Oct;121(10):1949-55. doi: 10.1016/j.ophtha.2014.04.040. Epub 2014 Jun 20.

9.

Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortium.

Klein R, Myers CE, Buitendijk GH, Rochtchina E, Gao X, de Jong PT, Sivakumaran TA, Burlutsky G, McKean-Cowdin R, Hofman A, Iyengar SK, Lee KE, Stricker BH, Vingerling JR, Mitchell P, Klein BE, Klaver CC, Wang JJ.

Am J Ophthalmol. 2014 Sep;158(3):513-24.e3. doi: 10.1016/j.ajo.2014.05.027. Epub 2014 May 28. Review.

10.

Misclassification can explain most apparent regression of age-related macular degeneration: results from multistate models with misclassification.

Gangnon RE, Lee KE, Klein BE, Iyengar SK, Sivakumaran TA, Klein R.

Invest Ophthalmol Vis Sci. 2014 Mar 20;55(3):1780-6. doi: 10.1167/iovs.13-12375.

11.

Markers of inflammation, oxidative stress, and endothelial dysfunction and the 20-year cumulative incidence of early age-related macular degeneration: the Beaver Dam Eye Study.

Klein R, Myers CE, Cruickshanks KJ, Gangnon RE, Danforth LG, Sivakumaran TA, Iyengar SK, Tsai MY, Klein BE.

JAMA Ophthalmol. 2014 Apr 1;132(4):446-55. doi: 10.1001/jamaophthalmol.2013.7671.

12.

Abnormalities in the alternative pathway of complement in children with hematopoietic stem cell transplant-associated thrombotic microangiopathy.

Jodele S, Licht C, Goebel J, Dixon BP, Zhang K, Sivakumaran TA, Davies SM, Pluthero FG, Lu L, Laskin BL.

Blood. 2013 Sep 19;122(12):2003-7. doi: 10.1182/blood-2013-05-501445. Epub 2013 Jun 27.

13.

Genetic analysis through OtoSeq of Pakistani families segregating prelingual hearing loss.

Shahzad M, Sivakumaran TA, Qaiser TA, Schultz JM, Hussain Z, Flanagan M, Bhinder MA, Kissell D, Greinwald JH Jr, Khan SN, Friedman TB, Zhang K, Riazuddin S, Riazuddin S, Ahmed ZM.

Otolaryngol Head Neck Surg. 2013 Sep;149(3):478-87. doi: 10.1177/0194599813493075. Epub 2013 Jun 14.

14.

Performance evaluation of the next-generation sequencing approach for molecular diagnosis of hereditary hearing loss.

Sivakumaran TA, Husami A, Kissell D, Zhang W, Keddache M, Black AP, Tinkle BT, Greinwald JH Jr, Zhang K.

Otolaryngol Head Neck Surg. 2013 Jun;148(6):1007-16. doi: 10.1177/0194599813482294. Epub 2013 Mar 22.

PMID:
23525850
15.

Risk alleles in CFH and ARMS2 and the long-term natural history of age-related macular degeneration: the Beaver Dam Eye Study.

Klein R, Myers CE, Meuer SM, Gangnon RE, Sivakumaran TA, Iyengar SK, Lee KE, Klein BE.

JAMA Ophthalmol. 2013 Mar;131(3):383-92. doi: 10.1001/jamaophthalmol.2013.713.

16.

Seven new loci associated with age-related macular degeneration.

Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, Igo RP Jr, Buitendijk GH, Sim X, Weeks DE, Guymer RH, Merriam JE, Francis PJ, Hannum G, Agarwal A, Armbrecht AM, Audo I, Aung T, Barile GR, Benchaboune M, Bird AC, Bishop PN, Branham KE, Brooks M, Brucker AJ, Cade WH, Cain MS, Campochiaro PA, Chan CC, Cheng CY, Chew EY, Chin KA, Chowers I, Clayton DG, Cojocaru R, Conley YP, Cornes BK, Daly MJ, Dhillon B, Edwards AO, Evangelou E, Fagerness J, Ferreyra HA, Friedman JS, Geirsdottir A, George RJ, Gieger C, Gupta N, Hagstrom SA, Harding SP, Haritoglou C, Heckenlively JR, Holz FG, Hughes G, Ioannidis JP, Ishibashi T, Joseph P, Jun G, Kamatani Y, Katsanis N, N Keilhauer C, Khan JC, Kim IK, Kiyohara Y, Klein BE, Klein R, Kovach JL, Kozak I, Lee CJ, Lee KE, Lichtner P, Lotery AJ, Meitinger T, Mitchell P, Mohand-Saïd S, Moore AT, Morgan DJ, Morrison MA, Myers CE, Naj AC, Nakamura Y, Okada Y, Orlin A, Ortube MC, Othman MI, Pappas C, Park KH, Pauer GJ, Peachey NS, Poch O, Priya RR, Reynolds R, Richardson AJ, Ripp R, Rudolph G, Ryu E, Sahel JA, Schaumberg DA, Scholl HP, Schwartz SG, Scott WK, Shahid H, Sigurdsson H, Silvestri G, Sivakumaran TA, Smith RT, Sobrin L, Souied EH, Stambolian DE, Stefansson H, Sturgill-Short GM, Takahashi A, Tosakulwong N, Truitt BJ, Tsironi EE, Uitterlinden AG, van Duijn CM, Vijaya L, Vingerling JR, Vithana EN, Webster AR, Wichmann HE, Winkler TW, Wong TY, Wright AF, Zelenika D, Zhang M, Zhao L, Zhang K, Klein ML, Hageman GS, Lathrop GM, Stefansson K, Allikmets R, Baird PN, Gorin MB, Wang JJ, Klaver CC, Seddon JM, Pericak-Vance MA, Iyengar SK, Yates JR, Swaroop A, Weber BH, Kubo M, Deangelis MM, Léveillard T, Thorsteinsdottir U, Haines JL, Farrer LA, Heid IM, Abecasis GR; AMD Gene Consortium.

Nat Genet. 2013 Apr;45(4):433-9, 439e1-2. doi: 10.1038/ng.2578. Epub 2013 Mar 3.

17.

The relationship of atherosclerosis to the 10-year cumulative incidence of age-related macular degeneration: the Beaver Dam studies.

Klein R, Cruickshanks KJ, Myers CE, Sivakumaran TA, Iyengar SK, Meuer SM, Schubert CR, Gangnon RE, Klein BE.

Ophthalmology. 2013 May;120(5):1012-9. doi: 10.1016/j.ophtha.2012.11.003. Epub 2013 Feb 8.

18.

Effect of the Y402H variant in the complement factor H gene on the incidence and progression of age-related macular degeneration: results from multistate models applied to the Beaver Dam Eye Study.

Gangnon RE, Lee KE, Klein BE, Iyengar SK, Sivakumaran TA, Klein R.

Arch Ophthalmol. 2012 Sep;130(9):1169-76. doi: 10.1001/archophthalmol.2012.693.

19.

Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma.

Vithana EN, Khor CC, Qiao C, Nongpiur ME, George R, Chen LJ, Do T, Abu-Amero K, Huang CK, Low S, Tajudin LA, Perera SA, Cheng CY, Xu L, Jia H, Ho CL, Sim KS, Wu RY, Tham CCY, Chew PTK, Su DH, Oen FT, Sarangapani S, Soumittra N, Osman EA, Wong HT, Tang G, Fan S, Meng H, Huong DTL, Wang H, Feng B, Baskaran M, Shantha B, Ramprasad VL, Kumaramanickavel G, Iyengar SK, How AC, Lee KY, Sivakumaran TA, Yong VHK, Ting SML, Li Y, Wang YX, Tay WT, Sim X, Lavanya R, Cornes BK, Zheng YF, Wong TT, Loon SC, Yong VKY, Waseem N, Yaakub A, Chia KS, Allingham RR, Hauser MA, Lam DSC, Hibberd ML, Bhattacharya SS, Zhang M, Teo YY, Tan DT, Jonas JB, Tai ES, Saw SM, Hon DN, Al-Obeidan SA, Liu J, Chau TNB, Simmons CP, Bei JX, Zeng YX, Foster PJ, Vijaya L, Wong TY, Pang CP, Wang N, Aung T.

Nat Genet. 2012 Oct;44(10):1142-1146. doi: 10.1038/ng.2390. Epub 2012 Aug 26.

20.

The relationship of cataract and cataract extraction to age-related macular degeneration: the Beaver Dam Eye Study.

Klein BE, Howard KP, Lee KE, Iyengar SK, Sivakumaran TA, Klein R.

Ophthalmology. 2012 Aug;119(8):1628-33. doi: 10.1016/j.ophtha.2012.01.050. Epub 2012 May 11.

21.

A 32 kb critical region excluding Y402H in CFH mediates risk for age-related macular degeneration.

Sivakumaran TA, Igo RP Jr, Kidd JM, Itsara A, Kopplin LJ, Chen W, Hagstrom SA, Peachey NS, Francis PJ, Klein ML, Chew EY, Ramprasad VL, Tay WT, Mitchell P, Seielstad M, Stambolian DE, Edwards AO, Lee KE, Leontiev DV, Jun G, Wang Y, Tian L, Qiu F, Henning AK, LaFramboise T, Sen P, Aarthi M, George R, Raman R, Das MK, Vijaya L, Kumaramanickavel G, Wong TY, Swaroop A, Abecasis GR, Klein R, Klein BE, Nickerson DA, Eichler EE, Iyengar SK.

PLoS One. 2011;6(10):e25598. doi: 10.1371/journal.pone.0025598. Epub 2011 Oct 12. Erratum in: PLoS One. 2018 Dec 20;13(12):e0209943.

22.

Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.

Ikram MK, Sim X, Jensen RA, Cotch MF, Hewitt AW, Ikram MA, Wang JJ, Klein R, Klein BE, Breteler MM, Cheung N, Liew G, Mitchell P, Uitterlinden AG, Rivadeneira F, Hofman A, de Jong PT, van Duijn CM, Kao L, Cheng CY, Smith AV, Glazer NL, Lumley T, McKnight B, Psaty BM, Jonasson F, Eiriksdottir G, Aspelund T; Global BPgen Consortium, Harris TB, Launer LJ, Taylor KD, Li X, Iyengar SK, Xi Q, Sivakumaran TA, Mackey DA, Macgregor S, Martin NG, Young TL, Bis JC, Wiggins KL, Heckbert SR, Hammond CJ, Andrew T, Fahy S, Attia J, Holliday EG, Scott RJ, Islam FM, Rotter JI, McAuley AK, Boerwinkle E, Tai ES, Gudnason V, Siscovick DS, Vingerling JR, Wong TY.

PLoS Genet. 2010 Oct 28;6(10):e1001184. doi: 10.1371/journal.pgen.1001184. Erratum in: PLoS Genet. 2010;6(11). doi: 10.1371/annotation/841bfadf-85d1-4059-894f-2863d73fa963. Xueling, Sim [corrected to Sim, Xueling].

23.

Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration.

Kopplin LJ, Igo RP Jr, Wang Y, Sivakumaran TA, Hagstrom SA, Peachey NS, Francis PJ, Klein ML, SanGiovanni JP, Chew EY, Pauer GJ, Sturgill GM, Joshi T, Tian L, Xi Q, Henning AK, Lee KE, Klein R, Klein BE, Iyengar SK.

Genes Immun. 2010 Dec;11(8):609-21. doi: 10.1038/gene.2010.39. Epub 2010 Sep 23.

24.

Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration.

SanGiovanni JP, Arking DE, Iyengar SK, Elashoff M, Clemons TE, Reed GF, Henning AK, Sivakumaran TA, Xu X, DeWan A, Agrón E, Rochtchina E, Sue CM, Wang JJ, Mitchell P, Hoh J, Francis PJ, Klein ML, Chew EY, Chakravarti A.

PLoS One. 2009;4(5):e5508. doi: 10.1371/journal.pone.0005508. Epub 2009 May 12.

25.

Combined effects of complement factor H genotypes, fish consumption, and inflammatory markers on long-term risk for age-related macular degeneration in a cohort.

Wang JJ, Rochtchina E, Smith W, Klein R, Klein BE, Joshi T, Sivakumaran TA, Iyengar S, Mitchell P.

Am J Epidemiol. 2009 Mar 1;169(5):633-41. doi: 10.1093/aje/kwn358. Epub 2008 Dec 13.

26.

A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction.

Robertson NG, Jones SM, Sivakumaran TA, Giersch AB, Jurado SA, Call LM, Miller CE, Maison SF, Liberman MC, Morton CC.

Hum Mol Genet. 2008 Nov 1;17(21):3426-34. doi: 10.1093/hmg/ddn236. Epub 2008 Aug 12.

27.

Impairment of SLC17A8 encoding vesicular glutamate transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice.

Ruel J, Emery S, Nouvian R, Bersot T, Amilhon B, Van Rybroek JM, Rebillard G, Lenoir M, Eybalin M, Delprat B, Sivakumaran TA, Giros B, El Mestikawy S, Moser T, Smith RJ, Lesperance MM, Puel JL.

Am J Hum Genet. 2008 Aug;83(2):278-92. doi: 10.1016/j.ajhg.2008.07.008.

28.

Toll-like receptor polymorphisms and age-related macular degeneration.

Edwards AO, Chen D, Fridley BL, James KM, Wu Y, Abecasis G, Swaroop A, Othman M, Branham K, Iyengar SK, Sivakumaran TA, Klein R, Klein BE, Tosakulwong N.

Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1652-9. doi: 10.1167/iovs.07-1378.

PMID:
18385087
29.

Complement factor H polymorphisms, renal phenotypes and age-related macular degeneration: the Blue Mountains Eye Study.

Xing C, Sivakumaran TA, Wang JJ, Rochtchina E, Joshi T, Smith W, Mitchell P, Iyengar SK.

Genes Immun. 2008 Apr;9(3):231-9. doi: 10.1038/gene.2008.10. Epub 2008 Mar 13.

PMID:
18340363
30.

Characterization of an abundant COL9A1 transcript in the cochlea with a novel 3' UTR: Expression studies and detection of miRNA target sequence.

Sivakumaran TA, Resendes BL, Robertson NG, Giersch AB, Morton CC.

J Assoc Res Otolaryngol. 2006 Jun;7(2):160-72. Epub 2006 Apr 19.

31.

Conservation of the RB1 gene in human and primates.

Sivakumaran TA, Shen P, Wall DP, Do BH, Kucheria K, Oefner PJ.

Hum Mutat. 2005 Apr;25(4):396-409. Erratum in: Hum Mutat. 2005 May;25(5):501.

PMID:
15776430
32.

A gene responsible for autosomal dominant auditory neuropathy (AUNA1) maps to 13q14-21.

Kim TB, Isaacson B, Sivakumaran TA, Starr A, Keats BJ, Lesperance MM.

J Med Genet. 2004 Nov;41(11):872-6. No abstract available.

33.

Haplotype and linkage disequilibrium analysis of the CRMP1 and EVC genes.

Sivakumaran TA, Lesperance MM.

Int J Mol Med. 2004 Nov;14(5):903-7.

PMID:
15492864
34.

Nongonadal neoplasia in patients with Turner syndrome.

Sivakumaran TA, Ghose S, Kumar H, Singha U, Kucheria K.

J Environ Pathol Toxicol Oncol. 1999;18(4):339-47. Review.

PMID:
15281247
35.

Mutational spectrum of the WFS1 gene in Wolfram syndrome, nonsyndromic hearing impairment, diabetes mellitus, and psychiatric disease.

Cryns K, Sivakumaran TA, Van den Ouweland JM, Pennings RJ, Cremers CW, Flothmann K, Young TL, Smith RJ, Lesperance MM, Van Camp G.

Hum Mutat. 2003 Oct;22(4):275-87. Review.

PMID:
12955714
36.

Human molecular cytogenetics: diagnosis, prognosis, and disease management.

Kucheria K, Jobanputra V, Talwar R, Ahmad ME, Dada R, Sivakumaran TA.

Teratog Carcinog Mutagen. 2003;Suppl 1:225-33.

PMID:
12616613
37.
38.

Mutations in the Wolfram syndrome 1 gene (WFS1) are a common cause of low frequency sensorineural hearing loss.

Bespalova IN, Van Camp G, Bom SJ, Brown DJ, Cryns K, DeWan AT, Erson AE, Flothmann K, Kunst HP, Kurnool P, Sivakumaran TA, Cremers CW, Leal SM, Burmeister M, Lesperance MM.

Hum Mol Genet. 2001 Oct 15;10(22):2501-8.

39.

Parental age in Indian patients with sporadic hereditary retinoblastoma.

Sivakumaran TA, Ghose S, Kumar H, A S, Kucheria K.

Ophthalmic Epidemiol. 2000 Dec;7(4):285-91.

PMID:
11262675
40.

Genetics of otosclerosis.

Sabitha R, Ramalingam R, Ramalingam KK, Sivakumaran TA, Ramesh A.

J Laryngol Otol. 1997 Feb;111(2):109-12.

PMID:
9102432
41.

Absence of pericentromeric heterochromatin (9qh-) in a patient with bilateral retinoblastoma.

Sivakumaran TA, Ghose S, Kumar H, Singha U, Kucheria K.

Acta Genet Med Gemellol (Roma). 1997;46(4):193-8.

PMID:
9862007
42.

Effects of inbreeding on reproductive losses in Kota tribe.

Sivakumaran TA, Karthikeyan S.

Acta Genet Med Gemellol (Roma). 1997;46(2):123-8.

PMID:
9492894

Supplemental Content

Loading ...
Support Center