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Items: 24


A data-mining approach for multiple structural alignment of proteins.

Siu WY, Mamoulis N, Yiu SM, Chan HL.

Bioinformation. 2010 Feb 28;4(8):366-70.


Evaluation of a school-based internship program for Chinese immigrant adolescents in the United States.

Ching AM, Yeh CJ, Siu WY, Wu KA, Okubo Y.

Adolescence. 2009 Autumn;44(175):601-20.


Polyploidization increases the sensitivity to DNA-damaging agents in mammalian cells.

Hau PM, Siu WY, Wong N, Lai PB, Poon RY.

FEBS Lett. 2006 Aug 21;580(19):4727-36. Epub 2006 Jul 28.


Stalled replication induces p53 accumulation through distinct mechanisms from DNA damage checkpoint pathways.

Ho CC, Siu WY, Lau A, Chan WM, Arooz T, Poon RY.

Cancer Res. 2006 Feb 15;66(4):2233-41.


Ubiquitination of p53 at multiple sites in the DNA-binding domain.

Chan WM, Mak MC, Fung TK, Lau A, Siu WY, Poon RY.

Mol Cancer Res. 2006 Jan;4(1):15-25.


The relative contribution of CHK1 and CHK2 to Adriamycin-induced checkpoint.

Ho CC, Siu WY, Chow JP, Lau A, Arooz T, Tong HY, Ng IO, Poon RY.

Exp Cell Res. 2005 Mar 10;304(1):1-15. Epub 2004 Nov 21.


How many mutant p53 molecules are needed to inactivate a tetramer?

Chan WM, Siu WY, Lau A, Poon RY.

Mol Cell Biol. 2004 Apr;24(8):3536-51.


Differential mode of regulation of the checkpoint kinases CHK1 and CHK2 by their regulatory domains.

Ng CP, Lee HC, Ho CW, Arooz T, Siu WY, Lau A, Poon RY.

J Biol Chem. 2004 Mar 5;279(10):8808-19. Epub 2003 Dec 16.


ING1b decreases cell proliferation through p53-dependent and -independent mechanisms.

Tsang FC, Po LS, Leung KM, Lau A, Siu WY, Poon RY.

FEBS Lett. 2003 Oct 23;553(3):277-85.


DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.

Chow JP, Siu WY, Fung TK, Chan WM, Lau A, Arooz T, Ng CP, Yamashita K, Poon RY.

Mol Biol Cell. 2003 Oct;14(10):3989-4002. Epub 2003 Jul 25.


Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.

Chow JP, Siu WY, Ho HT, Ma KH, Ho CC, Poon RY.

J Biol Chem. 2003 Oct 17;278(42):40815-28. Epub 2003 Aug 11.


The candidate tumor suppressor ING1b can stabilize p53 by disrupting the regulation of p53 by MDM2.

Leung KM, Po LS, Tsang FC, Siu WY, Lau A, Ho HT, Poon RY.

Cancer Res. 2002 Sep 1;62(17):4890-3.


Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins.

Fung TK, Siu WY, Yam CH, Lau A, Poon RY.

J Biol Chem. 2002 Sep 20;277(38):35140-9. Epub 2002 Jul 16.


MDM2 and MDMX can interact differently with ARF and members of the p53 family.

Wang X, Arooz T, Siu WY, Chiu CH, Lau A, Yamashita K, Poon RY.

FEBS Lett. 2001 Feb 16;490(3):202-8.


Cleavage of cyclin A at R70/R71 by the bacterial protease OmpT.

Yam CH, Siu WY, Kaganovich D, Ruderman JV, Poon RY.

Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):497-501. Epub 2001 Jan 2.


On the concentrations of cyclins and cyclin-dependent kinases in extracts of cultured human cells.

Arooz T, Yam CH, Siu WY, Lau A, Li KK, Poon RY.

Biochemistry. 2000 Aug 8;39(31):9494-501.


Degradation of cyclin A does not require its phosphorylation by CDC2 and cyclin-dependent kinase 2.

Yam CH, Siu WY, Lau A, Poon RY.

J Biol Chem. 2000 Feb 4;275(5):3158-67.


G1 versus G2 cell cycle arrest after adriamycin-induced damage in mouse Swiss3T3 cells.

Siu WY, Yam CH, Poon RY.

FEBS Lett. 1999 Nov 19;461(3):299-305.


MDM2 and MDMX inhibit the transcriptional activity of ectopically expressed SMAD proteins.

Yam CH, Siu WY, Arooz T, Chiu CH, Lau A, Wang XQ, Poon RY.

Cancer Res. 1999 Oct 15;59(20):5075-8.


MDM2 and MDMX bind and stabilize the p53-related protein p73.

Ongkeko WM, Wang XQ, Siu WY, Lau AW, Yamashita K, Harris AL, Cox LS, Poon RY.

Curr Biol. 1999 Jul 29-Aug 12;9(15):829-32.


Differential responses of proliferating versus quiescent cells to adriamycin.

Siu WY, Arooz T, Poon RY.

Exp Cell Res. 1999 Jul 10;250(1):131-41.


Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2.

Yam CH, Ng RW, Siu WY, Lau AW, Poon RY.

Mol Cell Biol. 1999 Jan;19(1):635-45.


Supplementation with vitamins C and E enhances cytokine production by peripheral blood mononuclear cells in healthy adults.

Jeng KC, Yang CS, Siu WY, Tsai YS, Liao WJ, Kuo JS.

Am J Clin Nutr. 1996 Dec;64(6):960-5.


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