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Items: 44

1.

On the use of superparamagnetic hydroxyapatite nanoparticles as an agent for magnetic and nuclear in vivo imaging.

Adamiano A, Iafisco M, Sandri M, Basini M, Arosio P, Canu T, Sitia G, Esposito A, Iannotti V, Ausanio G, Fragogeorgi E, Rouchota M, Loudos G, Lascialfari A, Tampieri A.

Acta Biomater. 2018 Jun;73:458-469. doi: 10.1016/j.actbio.2018.04.040. Epub 2018 Apr 22.

PMID:
29689381
2.

High mobility group box 1 orchestrates tissue regeneration via CXCR4.

Tirone M, Tran NL, Ceriotti C, Gorzanelli A, Canepari M, Bottinelli R, Raucci A, Di Maggio S, Santiago C, Mellado M, Saclier M, François S, Careccia G, He M, De Marchis F, Conti V, Ben Larbi S, Cuvellier S, Casalgrandi M, Preti A, Chazaud B, Al-Abed Y, Messina G, Sitia G, Brunelli S, Bianchi ME, Vénéreau E.

J Exp Med. 2018 Jan 2;215(1):303-318. doi: 10.1084/jem.20160217. Epub 2017 Dec 4.

3.

Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.

Schiroli G, Ferrari S, Conway A, Jacob A, Capo V, Albano L, Plati T, Castiello MC, Sanvito F, Gennery AR, Bovolenta C, Palchaudhuri R, Scadden DT, Holmes MC, Villa A, Sitia G, Lombardo A, Genovese P, Naldini L.

Sci Transl Med. 2017 Oct 11;9(411). pii: eaan0820. doi: 10.1126/scitranslmed.aan0820.

PMID:
29021165
4.

New players in non-alcoholic fatty liver disease induced carcinogenesis: lipid dysregulation impairs liver immune surveillance.

Tran NL, Sitia G.

Hepatobiliary Surg Nutr. 2016 Dec;5(6):511-514. doi: 10.21037/hbsn.2016.11.08. No abstract available.

5.

IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment.

Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran NL, Aiolfi R, Marra P, Esposito A, Cipriani F, Aldrighetti L, Iannacone M, Naldini L, Guidotti LG, Sitia G.

EMBO Mol Med. 2016 Feb 1;8(2):155-70. doi: 10.15252/emmm.201505395.

6.

Immunosurveillance of the liver by intravascular effector CD8(+) T cells.

Guidotti LG, Inverso D, Sironi L, Di Lucia P, Fioravanti J, Ganzer L, Fiocchi A, Vacca M, Aiolfi R, Sammicheli S, Mainetti M, Cataudella T, Raimondi A, Gonzalez-Aseguinolaza G, Protzer U, Ruggeri ZM, Chisari FV, Isogawa M, Sitia G, Iannacone M.

Cell. 2015 Apr 23;161(3):486-500. doi: 10.1016/j.cell.2015.03.005. Epub 2015 Apr 16.

7.

Towards personalized medicine in chronic HBV patients?

Sitia G.

Liver Int. 2015 Jul;35(7):1783-5. doi: 10.1111/liv.12806. No abstract available.

PMID:
25676897
8.

Chronic hepatitis B: role of anti-platelet therapy in inflammation control.

Aiolfi R, Sitia G.

Cell Mol Immunol. 2015 May;12(3):264-8. doi: 10.1038/cmi.2014.124. Epub 2015 Jan 12. Review.

9.

Platelets promote liver immunopathology contributing to hepatitis B virus-mediated hepatocarcinogenesis.

Sitia G.

Semin Oncol. 2014 Jun;41(3):402-5. doi: 10.1053/j.seminoncol.2014.04.013. Epub 2014 Apr 24. Review.

PMID:
25023356
10.

The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver.

Panattoni M, Maiorino L, Lukacs A, Zentilin L, Mazza D, Sanvito F, Sitia G, Guidotti LG, Pardi R.

Hepatology. 2014 Jun;59(6):2331-43. doi: 10.1002/hep.27028. Epub 2014 Apr 30.

PMID:
24452456
11.

Emerging role of dual antiplatelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma.

Aiolfi R, Sitia G.

J Hepatocell Carcinoma. 2014 Nov 13;1:183-6. doi: 10.2147/JHC.S48763. eCollection 2014. Review.

12.

Bisphosphonates target B cells to enhance humoral immune responses.

Tonti E, Jiménez de Oya N, Galliverti G, Moseman EA, Di Lucia P, Amabile A, Sammicheli S, De Giovanni M, Sironi L, Chevrier N, Sitia G, Gennari L, Guidotti LG, von Andrian UH, Iannacone M.

Cell Rep. 2013 Oct 31;5(2):323-30. doi: 10.1016/j.celrep.2013.09.004. Epub 2013 Oct 10.

13.

Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma.

Sitia G, Iannacone M, Guidotti LG.

J Hepatol. 2013 Nov;59(5):1135-8. doi: 10.1016/j.jhep.2013.05.040. Epub 2013 Jun 4.

14.

Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity.

Castagnaro L, Lenti E, Maruzzelli S, Spinardi L, Migliori E, Farinello D, Sitia G, Harrelson Z, Evans SM, Guidotti LG, Harvey RP, Brendolan A.

Immunity. 2013 Apr 18;38(4):782-91. doi: 10.1016/j.immuni.2012.12.005.

15.

Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.

Sitia G, Aiolfi R, Di Lucia P, Mainetti M, Fiocchi A, Mingozzi F, Esposito A, Ruggeri ZM, Chisari FV, Iannacone M, Guidotti LG.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):E2165-72. doi: 10.1073/pnas.1209182109. Epub 2012 Jul 2.

16.

AAV6-mediated systemic shRNA delivery reverses disease in a mouse model of facioscapulohumeral muscular dystrophy.

Bortolanza S, Nonis A, Sanvito F, Maciotta S, Sitia G, Wei J, Torrente Y, Di Serio C, Chamberlain JR, Gabellini D.

Mol Ther. 2011 Nov;19(11):2055-64. doi: 10.1038/mt.2011.153. Epub 2011 Aug 9.

17.

Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis.

Sitia G, Iannacone M, Aiolfi R, Isogawa M, van Rooijen N, Scozzesi C, Bianchi ME, von Andrian UH, Chisari FV, Guidotti LG.

PLoS Pathog. 2011 Jun;7(6):e1002061. doi: 10.1371/journal.ppat.1002061. Epub 2011 Jun 2.

18.

Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation.

Tomasoni R, Basso V, Pilipow K, Sitia G, Saccani S, Agresti A, Mietton F, Natoli G, Colombetti S, Mondino A.

Eur J Immunol. 2011 Jul;41(7):2086-96. doi: 10.1002/eji.201041130.

19.

Role of CCL2/MCP-1 in islet transplantation.

Melzi R, Mercalli A, Sordi V, Cantarelli E, Nano R, Maffi P, Sitia G, Guidotti LG, Secchi A, Bonifacio E, Piemonti L.

Cell Transplant. 2010;19(8):1031-46. doi: 10.3727/096368910X514639. Epub 2010 Jun 11.

PMID:
20546673
20.

Bone marrow as an alternative site for islet transplantation.

Cantarelli E, Melzi R, Mercalli A, Sordi V, Ferrari G, Lederer CW, Mrak E, Rubinacci A, Ponzoni M, Sitia G, Guidotti LG, Bonifacio E, Piemonti L.

Blood. 2009 Nov 12;114(20):4566-74. doi: 10.1182/blood-2009-03-209973. Epub 2009 Sep 22.

21.

On the role of platelets in the pathogenesis of viral hepatitis.

Iannacone M, Sitia G, Guidotti LG.

J Hepatol. 2009 Sep;51(3):599-600. doi: 10.1016/j.jhep.2009.05.005. Epub 2009 May 21. No abstract available.

22.

Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.

De Palma M, Mazzieri R, Politi LS, Pucci F, Zonari E, Sitia G, Mazzoleni S, Moi D, Venneri MA, Indraccolo S, Falini A, Guidotti LG, Galli R, Naldini L.

Cancer Cell. 2008 Oct 7;14(4):299-311. doi: 10.1016/j.ccr.2008.09.004.

23.

Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.

Iannacone M, Sitia G, Isogawa M, Whitmire JK, Marchese P, Chisari FV, Ruggeri ZM, Guidotti LG.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):629-34. doi: 10.1073/pnas.0711200105. Epub 2008 Jan 9.

24.

Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus.

Iannacone M, Sitia G, Narvaiza I, Ruggeri ZM, Guidotti LG.

Clin Vaccine Immunol. 2007 Nov;14(11):1532-5. Epub 2007 Sep 19.

25.

A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.

Ivanov S, Dragoi AM, Wang X, Dallacosta C, Louten J, Musco G, Sitia G, Yap GS, Wan Y, Biron CA, Bianchi ME, Wang H, Chu WM.

Blood. 2007 Sep 15;110(6):1970-81. Epub 2007 Jun 4.

26.

HBV pathogenesis in animal models: recent advances on the role of platelets.

Iannacone M, Sitia G, Ruggeri ZM, Guidotti LG.

J Hepatol. 2007 Apr;46(4):719-26. Epub 2007 Jan 29. Review.

27.

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance.

Brown BD, Sitia G, Annoni A, Hauben E, Sergi LS, Zingale A, Roncarolo MG, Guidotti LG, Naldini L.

Blood. 2007 Apr 1;109(7):2797-805.

28.

[Innate immunity restoration in patients with HIV/AIDS infection associated with antiretroviral therapy].

Afani A, Jiusán L, Raby P, Sitia G, Puente J, Sepúlveda C, Miranda D, Cabrera R, Guidotti L, Lanza P.

Rev Med Chil. 2006 Jun;134(6):689-96. Epub 2006 Aug 14. Spanish.

29.

Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients.

Trifari S, Sitia G, Aiuti A, Scaramuzza S, Marangoni F, Guidotti LG, Martino S, Saracco P, Notarangelo LD, Roncarolo MG, Dupré L.

J Immunol. 2006 Nov 15;177(10):7451-61.

30.

Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice.

Sitia G, Iannacone M, Müller S, Bianchi ME, Guidotti LG.

J Leukoc Biol. 2007 Jan;81(1):100-7. Epub 2006 Aug 25.

PMID:
16935945
31.

Reduced severity of liver ischemia/reperfusion injury following hepatic resection in humans is associated with enhanced intrahepatic expression of Th2 cytokines.

Pulitanò C, Sitia G, Aldrighetti L, Finazzi R, Arru M, Catena M, Guidotti LG, Ferla G.

Hepatol Res. 2006 Sep;36(1):20-6. Epub 2006 Jul 10.

PMID:
16831568
32.

Naive HIV/HCV-coinfected patients have higher intrahepatic pro-inflammatory cytokines than coinfected patients treated with antiretroviral therapy.

Sitia G, De Bona A, Bagaglio S, Galli L, Paties CT, Uberti-Foppa C, Guidotti LG, Lazzarin A, Morsica G.

Antivir Ther. 2006;11(3):385-9.

PMID:
16759056
33.

Liver fibrosis in HIV-positive patients with hepatitis C virus: role of persistently normal alanine aminotransferase levels.

Uberti-Foppa C, De Bona A, Galli L, Sitia G, Gallotta G, Sagnelli C, Paties C, Lazzarin A.

J Acquir Immune Defic Syndr. 2006 Jan 1;41(1):63-7.

PMID:
16340475
34.

Platelets mediate cytotoxic T lymphocyte-induced liver damage.

Iannacone M, Sitia G, Isogawa M, Marchese P, Castro MG, Lowenstein PR, Chisari FV, Ruggeri ZM, Guidotti LG.

Nat Med. 2005 Nov;11(11):1167-9. Epub 2005 Oct 30.

35.

MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs.

Sitia G, Isogawa M, Iannacone M, Campbell IL, Chisari FV, Guidotti LG.

J Clin Invest. 2004 Apr;113(8):1158-67.

36.

Impact of HAART on liver histology of HIV/HCV coinfected patients.

De Bona A, Sitia G, Uberti-Foppa C, Galli L, Ciuffreda D, Gallotta G, Paties C, Lazzarin A.

J Biol Regul Homeost Agents. 2003 Apr-Jun;17(2):195-7.

PMID:
14518723
37.

Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes.

Sitia G, Isogawa M, Kakimi K, Wieland SF, Chisari FV, Guidotti LG.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13717-22. Epub 2002 Oct 4.

38.

Mother-to-child transmission of TT virus: sequence analysis of non-coding region of TT virus in infected mother-infant pairs.

Bagaglio S, Sitia G, Prati D, Cella D, Hasson H, Novati R, Lazzarin A, Morsica G.

Arch Virol. 2002 Apr;147(4):803-12.

PMID:
12038689
39.

Evolution of the E2 region of hepatitis C virus in an infant infected by mother-to-infant transmission.

Sitia G, Cella D, De Mitri MS, Novati R, Foppa CU, Perackis K, Bianchi C, Lazzarin A, Morsica G.

J Med Virol. 2001 Aug;64(4):476-81.

PMID:
11468732
40.

Acute self-limiting hepatitis C after possible sexual exposure: sequence analysis of the E-2 region of the infected patient and sexual partner.

Morsica G, Sitia G, Bernardi MT, Tambussi G, Novati R, De Bona A, Gianotti N, Lazzarin A.

Scand J Infect Dis. 2001;33(2):116-20.

PMID:
11233845
41.

Ribavirin therapy for chronic hepatitis C does not modify HIV viral load in HIV-1 positive patients under antiretroviral treatment.

Morsica G, De Bona A, Foppa CU, Sitia G, Finazzi R, Lazzarin A.

AIDS. 2000 Jul 28;14(11):1656-8. No abstract available.

PMID:
10983654
42.

GB virus C and hepatitis C virus infection in patients with mixed cryoglobulinemia.

Morsica G, Sitia G, Roccatello D.

Ann Intern Med. 2000 Sep 5;133(5):394-5. No abstract available.

PMID:
10979891
43.

Effect of increasing dose of interferon on the evolution of hepatitis C virus 1b quasispecies.

De Mitri MS, Mele L, Morsica G, Chen CH, Sitia G, Gramenzi A, Andreone P, Alberti A, Bernardi M, Pisi E.

J Med Virol. 2000 Feb;60(2):133-8.

PMID:
10596011
44.

Replication of hepatitis C virus in B lymphocytes (CD19+)

Morsica G, Tambussi G, Sitia G, Novati R, Lazzarin A, Lopalco L, Mukenge S.

Blood. 1999 Aug 1;94(3):1138-9. No abstract available.

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