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Items: 1 to 50 of 176

1.

Predictive value and clinical significance of increased SSAT-1 activity in healthy adults.

Tappia PS, Maksymiuk AW, Sitar DS, Akhtar PS, Khatun N, Parveen R, Ahmed R, Ahmed RB, Cheng B, Huang G, Bach H, Hiebert B, Ramjiawan B.

Future Sci OA. 2019 Jul 1;5(7):FSO400. doi: 10.2144/fsoa-2019-0023.

2.

Liquid Biopsy in Lung Cancer Screening: The Contribution of Metabolomics. Results of A Pilot Study.

Singhal S, Rolfo C, Maksymiuk AW, Tappia PS, Sitar DS, Russo A, Akhtar PS, Khatun N, Rahnuma P, Rashiduzzaman A, Ahmed Bux R, Huang G, Ramjiawan B.

Cancers (Basel). 2019 Jul 29;11(8). pii: E1069. doi: 10.3390/cancers11081069.

3.

Use of amantadine as substrate for SSAT-1 activity as a reliable clinical diagnostic assay for breast and lung cancer.

Maksymiuk AW, Tappia PS, Sitar DS, Akhtar PS, Khatun N, Parveen R, Ahmed R, Ahmed RB, Cheng B, Huang G, Bach H, Hiebert B, Ramjiawan B.

Future Sci OA. 2018 Dec 11;5(2):FSO365. doi: 10.4155/fsoa-2018-0106. eCollection 2019 Feb.

4.

Spermidine/spermine N1-acetyltransferase-1 as a diagnostic biomarker in human cancer.

Maksymiuk AW, Sitar DS, Ahmed R, Cheng B, Bach H, Bagchi RA, Aroutiounova N, Tappia PS, Ramjiawan B.

Future Sci OA. 2018 Sep 10;4(10):FSO345. doi: 10.4155/fsoa-2018-0077. eCollection 2018 Dec.

5.

Theophylline-7β-d-Ribofuranoside (Theonosine), a New Theophylline Metabolite Generated in Human and Animal Lung Tissue.

Sitar DS, Bowen JM, He J, Tesoro A, Spino M.

Pharmaceutics. 2017 Aug 14;9(3). pii: E28. doi: 10.3390/pharmaceutics9030028.

6.

In vitro evaluation of the effect of linezolid and levofloxacin on Bacillus anthracis toxin production, spore formation and cell growth.

Head BM, Alfa M, Sitar DS, Rubinstein E, Meyers AF.

J Antimicrob Chemother. 2017 Feb;72(2):417-420. doi: 10.1093/jac/dkw427. Epub 2016 Oct 17.

PMID:
27798209
7.

Quantification of cefazolin in serum and adipose tissue by ultra high performance liquid chromatography-Tandem mass spectrometry (UHPLC-MS/MS): application to a pilot study of obese women undergoing cesarean delivery.

Lillico R, Sayre CL, Sitar DS, Davies NM, Baron CM, Lakowski TM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Sep 15;1031:94-98. doi: 10.1016/j.jchromb.2016.07.032. Epub 2016 Jul 18.

PMID:
27469905
8.

The evolving role of the Journal of Clinical Pharmacology and its contributions to the discipline.

Sitar DS.

J Clin Pharmacol. 2013 Dec;53(12):1227. doi: 10.1002/jcph.202. Epub 2013 Oct 10. No abstract available.

PMID:
24122700
9.

Clinical pharmacology confounders in older adults.

Sitar DS.

Expert Rev Clin Pharmacol. 2012 Jul;5(4):397-402. doi: 10.1586/ecp.12.32. Review.

PMID:
22943119
10.

The influence of sparse data sampling on population pharmacokinetics: a post hoc analysis of a pharmacokinetic study of morphine in healthy volunteers.

Ariano RE, Duke PC, Sitar DS.

Clin Ther. 2012 Mar;34(3):668-76. doi: 10.1016/j.clinthera.2012.01.023. Epub 2012 Feb 28.

PMID:
22381713
11.
12.

The seduction of biomarkers in the practice of medicine and the tyranny of power in the drug approval process: lessons from niacin.

Lehmann DF, Sitar DS.

J Clin Pharmacol. 2011 Nov;51(11):1496-8. doi: 10.1177/0091270011420253. No abstract available.

PMID:
21998350
13.

Optimizing drug development and use in patients with kidney disease.

Nolin TD, Arya V, Sitar DS, Pfister M.

J Clin Pharmacol. 2011 May;51(5):628-30. doi: 10.1177/0091270011402500. No abstract available.

PMID:
21525394
14.

Enteric absorption and pharmacokinetics of oseltamivir in critically ill patients with pandemic (H1N1) influenza.

Ariano RE, Sitar DS, Zelenitsky SA, Zarychanski R, Pisipati A, Ahern S, Kanji S, Rello J, Kumar A.

CMAJ. 2010 Mar 9;182(4):357-63. doi: 10.1503/cmaj.092127. Epub 2010 Feb 16.

15.

Protein kinase inhibition differentially regulates organic cation transport.

Gerlyand AM, Sitar DS.

Can J Physiol Pharmacol. 2009 Oct;87(10):821-30. doi: 10.1139/Y09-072.

16.

Aging issues in drug disposition and efficacy.

Sitar DS.

Proc West Pharmacol Soc. 2007;50:16-20. Review.

PMID:
18605223
17.

Acyclovir bioavailability in patients with acute myelogenous leukemia treated with daunorubicin and cytarabine.

Sitar DS, Aoki FY, Bow EJ.

J Clin Pharmacol. 2008 Aug;48(8):995-8. doi: 10.1177/0091270008319708. Epub 2008 May 21. No abstract available.

PMID:
18495946
18.

Use of antiviral prophylaxis in influenza outbreaks in long term care facilities.

McGeer A, Sitar DS, Tamblyn SE, Faron K, Orr P, Aoki FY.

Can J Infect Dis. 2000 Jul;11(4):187-92.

19.

Adventures in drug disposition: pas seulement pâté de foie.

Sitar DS.

Can J Physiol Pharmacol. 2007 Dec;85(12):1215-25.

PMID:
18066123
20.

Protective effect of minocycline treatment on striatal ischemia.

Peeling J, Yan H, Buist R, Sitar DS, Corbett D.

J Stroke Cerebrovasc Dis. 2006 May-Jun;15(3):101-5.

PMID:
17904060
21.

British and Canadian views on the ethics of paediatric clinical trials.

Sammons HM, Malhotra J, Choonara I, Sitar DS, Matsui D, Rieder MJ.

Eur J Clin Pharmacol. 2007 May;63(5):431-6. Epub 2007 Mar 16.

PMID:
17364191
22.

Nicotine dose-concentration relationship and pregnancy outcomes in rat: biologic plausibility and implications for future research.

Hussein J, Farkas S, MacKinnon Y, Ariano RE, Sitar DS, Hasan SU.

Toxicol Appl Pharmacol. 2007 Jan 1;218(1):1-10. Epub 2006 Oct 28.

PMID:
17141291
23.

NH4+ modulates renal tubule amantadine transport independently of intracellular pH changes.

Goralski KB, Bose R, Sitar DS.

Eur J Pharmacol. 2006 Jul 10;541(1-2):87-94. Epub 2006 May 7.

PMID:
16750190
24.

Validity of a prescription claims database to estimate medication adherence in older persons.

Grymonpre R, Cheang M, Fraser M, Metge C, Sitar DS.

Med Care. 2006 May;44(5):471-7.

PMID:
16641666
25.

Prenatal cigarette smoke exposure: pregnancy outcome and gestational changes in plasma nicotine concentration, hematocrit, and carboxyhemoglobin in a newly standardized rat model.

Farkas S, Hussein J, Ariano RE, Sitar DS, Hasan SU.

Toxicol Appl Pharmacol. 2006 Jul 15;214(2):118-25. Epub 2006 Feb 13.

PMID:
16473381
26.

Adequacy of a vancomycin dosing regimen in patients receiving high-flux hemodialysis.

Ariano RE, Fine A, Sitar DS, Rexrode S, Zelenitsky SA.

Am J Kidney Dis. 2005 Oct;46(4):681-7.

PMID:
16183423
27.

An evaluation of an optimal sampling strategy for meropenem in febrile neutropenics.

Ariano RE, Zelenitsky SA, Nyhlén A, Sitar DS.

J Clin Pharmacol. 2005 Jul;45(7):832-5.

PMID:
15951473
28.

Old drugs - old people - new insights.

Sitar DS.

Can J Clin Pharmacol. 2005 Winter;12(1):e28-32. Epub 2005 Jan 10.

PMID:
15650276
29.

Pharmacokinetics and pharmacodynamics of meropenem in febrile neutropenic patients with bacteremia.

Ariano RE, Nyhlén A, Donnelly JP, Sitar DS, Harding GK, Zelenitsky SA.

Ann Pharmacother. 2005 Jan;39(1):32-8. Epub 2004 Dec 14.

PMID:
15598967
30.

Effect of anticholinergic drugs on the efficacy of activated charcoal.

Green R, Sitar DS, Tenenbein M.

J Toxicol Clin Toxicol. 2004;42(3):267-72.

PMID:
15362593
31.

Functional map of TEA transport activity in isolated rabbit renal proximal tubules.

Wright SH, Evans KK, Zhang X, Cherrington NJ, Sitar DS, Dantzler WH.

Am J Physiol Renal Physiol. 2004 Sep;287(3):F442-51. Epub 2004 May 4.

32.

An amantadine hydrochloride dosing program adjusted for renal function during an influenza outbreak in elderly institutionalized patients.

Kolbe F, Sitar DS, Papaioannou A, Campbell G.

Can J Clin Pharmacol. 2003 Fall;10(3):119-22.

PMID:
14506511
33.

Bayesian pharmacokinetic analysis of a gentamicin nomogram in neonates: a retrospective study.

Ariano RE, Sitar DS, Davi M, Zelenitsky SA.

Curr Ther Res Clin Exp. 2003 Mar;64(3):178-88. doi: 10.1016/S0011-393X(03)00022-5.

34.

Activation of phospholipases A2 and D of a human neuroblastoma cell line (LA-N-2) by N-dodecyl-L-lysine amide (compound 24), a putative G protein activator: characteristics of inhibition by (-)-nicotine.

Garnham BM, Fitzpatrick-Wong S, Schunack W, Nürnberg B, Sorrentino G, Parkinson FE, Kanfer JN, Sitar DS.

Neurochem Res. 2002 Dec;27(12):1613-8.

PMID:
12515313
35.

The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.

Goralski KB, Lou G, Prowse MT, Gorboulev V, Volk C, Koepsell H, Sitar DS.

J Pharmacol Exp Ther. 2002 Dec;303(3):959-68.

PMID:
12438515
36.

NMDA receptor antagonists to characterize rat renal organic cation transporter function.

Fourie J, Escobar MR, Sitar DS.

Eur J Pharmacol. 2002 Sep 27;452(1):1-10.

PMID:
12323380
37.

How long after drug ingestion is activated charcoal still effective?

Green R, Grierson R, Sitar DS, Tenenbein M.

J Toxicol Clin Toxicol. 2001;39(6):601-5.

PMID:
11762668
38.
39.

Interaction between N-acetylcysteine and activated charcoal: implications for the treatment of acetaminophen poisoning.

Tenenbein PK, Sitar DS, Tenenbein M.

Pharmacotherapy. 2001 Nov;21(11):1331-6.

PMID:
11714205
40.

Population pharmacokinetics of fentanyl in healthy volunteers.

Ariano RE, Duke PC, Sitar DS.

J Clin Pharmacol. 2001 Jul;41(7):757-63.

PMID:
11452708
41.

Safe use of the CXCR4 inhibitor ALX40-4C in humans.

Doranz BJ, Filion LG, Diaz-Mitoma F, Sitar DS, Sahai J, Baribaud F, Orsini MJ, Benovic JL, Cameron W, Doms RW.

AIDS Res Hum Retroviruses. 2001 Apr 10;17(6):475-86.

PMID:
11350661
42.

Vitamin A and risk of HIV-1 seroconversion among Kenyan men with genital ulcers.

MacDonald KS, Malonza I, Chen DK, Nagelkerke NJ, Nasio JM, Ndinya-Achola J, Bwayo JJ, Sitar DS, Aoki FY, Plummer FA.

AIDS. 2001 Mar 30;15(5):635-9.

PMID:
11317002
43.

Spermidine/spermine n(1)-acetyltransferase catalyzes amantadine acetylation.

Bras AP, Jänne J, Porter CW, Sitar DS.

Drug Metab Dispos. 2001 May;29(5):676-80.

PMID:
11302933
45.
46.

Short course antibiotics for acute otitis media.

Kozyrskyj AL, Hildes-Ripstein GE, Longstaffe SE, Wincott JL, Sitar DS, Klassen TP, Moffatt ME.

Cochrane Database Syst Rev. 2000;(2):CD001095. Review. Update in: Cochrane Database Syst Rev. 2010;(9):CD001095.

PMID:
10796591
47.

Gastric lavage for liquid poisons.

Grierson R, Green R, Sitar DS, Tenenbein M.

Ann Emerg Med. 2000 May;35(5):435-9.

PMID:
10783405
48.

Antibiotic-heparin lock: in vitro antibiotic stability combined with heparin in a central venous catheter.

Vercaigne LM, Sitar DS, Penner SB, Bernstein K, Wang GQ, Burczynski FJ.

Pharmacotherapy. 2000 Apr;20(4):394-9.

PMID:
10772369
49.

'Pseudo' treatment failure of pulmonary tuberculosis in association with a tuberculoma.

Long R, Chomyc S, Der E, Sitar DS.

Can Respir J. 2000 Jan-Feb;7(1):79-83.

50.

Amyloid beta peptide membrane perturbation is the basis for its biological effects.

Kanfer JN, Sorrentino G, Sitar DS.

Neurochem Res. 1999 Dec;24(12):1621-30. Review.

PMID:
10591414

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